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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 105454372.

DOT1L deletion impairs the development of cortical parvalbumin-expressing interneurons

Arquimedes Cheffer, Marta Garcia-Miralles, Esther Maier, Ipek Akol, Henriette Franz, Vandana Shree Vedartham Srinivasan, Tanja Vogel

Cereb Cortex. 2023 Oct 1; 33(19): 10272–10285. Published online 2023 Aug 11. doi: 10.1093/cercor/bhad281

PMCID:: PMC10545437

Abstract Article PDF–2.8M

Select item 94340833.

Schwann cell precursors represent a neural crest‐like state with biased multipotency

Maria Eleni Kastriti, Louis Faure, Dorothea Von Ahsen, Thibault Gerald Bouderlique, Johan Boström, Tatiana Solovieva, Cameron Jackson, Marianne Bronner, Dies Meijer, Saida Hadjab, Francois Lallemend, Alek Erickson, Marketa Kaucka, Viacheslav Dyachuk, Thomas Perlmann, Laura Lahti, Jan Krivanek, Jean‐Francois Brunet, Kaj Fried, Igor Adameyko

EMBO J. 2022 Sep; 41(17): e108780. Published online 2022 Jul 11. doi: 10.15252/embj.2021108780

PMCID:: PMC9434083

Abstract Article PDF–8.4M

Select item 91330024.

Serotonin limits generation of chromaffin cells during adrenal organ development

Polina Kameneva, Victoria I. Melnikova, Maria Eleni Kastriti, Anastasia Kurtova, Emil Kryukov, Aliia Murtazina, Louis Faure, Irina Poverennaya, Artem V. Artemov, Tatiana S. Kalinina, Nikita V. Kudryashov, Michael Bader, Jan Skoda, Petr Chlapek, Lucie Curylova, Lukas Sourada, Jakub Neradil, Marketa Tesarova, Massimo Pasqualetti, Patricia Gaspar, Vasily D. Yakushov, Boris I. Sheftel, Tomas Zikmund, Jozef Kaiser, Kaj Fried, Natalia Alenina, Elena E. Voronezhskaya, Igor Adameyko

Nat Commun. 2022; 13: 2901. Published online 2022 May 25. doi: 10.1038/s41467-022-30438-w

PMCID:: PMC9133002

Abstract Article PDF–8.9M

Select item 84905185.

Upregulated NMDAR-mediated GABAergic transmission underlies autistic-like deficits in Htr3a knockout mice

Lang Huang, Jing Wang, Guanmei Liang, Yue Gao, Shi-Yang Jin, Jian Hu, Xiaoxue Yang, Jianpei Lao, Jinfa Chen, Zhou-Cai Luo, Cuixia Fan, Li Xiong, Xinhong Zhu, Tian-Ming Gao, Mei Zhong, Xinping Yang

Theranostics. 2021; 11(19): 9296–9310. Published online 2021 Sep 7. doi: 10.7150/thno.60531

PMCID:: PMC8490518

Abstract Article PDF–2.2M

Select item 83132396.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 78872237.

Asymmetric opening of the homopentameric 5-HT_3A serotonin receptor in lipid bilayers

Yingyi Zhang, Patricia M. Dijkman, Rongfeng Zou, Martina Zandl-Lang, Ricardo M. Sanchez, Luise Eckhardt-Strelau, Harald Köfeler, Horst Vogel, Shuguang Yuan, Mikhail Kudryashev

Nat Commun. 2021; 12: 1074. Published online 2021 Feb 16. doi: 10.1038/s41467-021-21016-7

PMCID:: PMC7887223

Abstract Article PDF–6.7M

Select item 76551098.

High-resolution structures of multiple 5-HT_3AR-setron complexes reveal a novel mechanism of competitive inhibition

Sandip Basak, Arvind Kumar, Steven Ramsey, Eric Gibbs, Abhijeet Kapoor, Marta Filizola, Sudha Chakrapani

eLife. 2020; 9: e57870. Published online 2020 Oct 16. doi: 10.7554/eLife.57870

PMCID:: PMC7655109

Abstract Article PDF–7.6M

Select item 69714879.

Serotonin Regulates Adult β-Cell Mass by Stimulating Perinatal β-Cell Proliferation

Joon Ho Moon, Yeong Gi Kim, Kyuho Kim, Sho Osonoi, Shuang Wang, Diane C. Saunders, Juehu Wang, Katherine Yang, Hyeongseok Kim, Junguee Lee, Ji-Seon Jeong, Ronadip R. Banerjee, Seung K. Kim, Yingjie Wu, Hiroki Mizukami, Alvin C. Powers, Michael S. German, Hail Kim

Diabetes. 2020 Feb; 69(2): 205–214. Published online 2019 Dec 5. doi: 10.2337/db19-0546

PMCID:: PMC6971487

Abstract Article PDF–2.0M

Select item 695537910.

Microsecond-timescale simulations suggest 5-HT–mediated preactivation of the 5-HT_3A serotonin receptor

Nicholas B. Guros, Arvind Balijepalli, Jeffery B. Klauda

Proc Natl Acad Sci U S A. 2020 Jan 7; 117(1): 405–414. Published online 2019 Dec 23. doi: 10.1073/pnas.1908848117

PMCID:: PMC6955379

Abstract Article PDF–1.9M

Select item 675850311.

The 5-HT₃ Subtype of Serotonin Receptor Contributes to Nociceptive Processing via a Novel Subset of Myelinated and Unmyelinated Nociceptors

Karla P. Zeitz, Nicolas Guy, Annika B. Malmberg, Sahera Dirajlal, William J. Martin, Linda Sun, Douglas W. Bonhaus, Cheryl L. Stucky, David Julius, Allan I. Basbaum

J Neurosci. 2002 Feb 1; 22(3): 1010–1019. doi: 10.1523/JNEUROSCI.22-03-01010.2002

PMCID:: PMC6758503

Abstract Article PDF–482K

Select item 672932412.

Uropathic Observations in Mice Expressing a Constitutively Active Point Mutation in the 5-HT_3A Receptor Subunit

Anindya Bhattacharya, Hong Dang, Quan-Ming Zhu, Birthe Schnegelsberg, Nora Rozengurt, Gary Cain, Rachelle Prantil, David A. Vorp, Nicholas Guy, David Julius, Anthony P. D. W. Ford, Henry A. Lester, Debra A. Cockayne

J Neurosci. 2004 Jun 16; 24(24): 5537–5548. doi: 10.1523/JNEUROSCI.5658-03.2004

PMCID:: PMC6729324

Abstract Article PDF–593K

Select item 661404413.

Conformational transitions of the serotonin 5-HT3 receptor

Lucie Polovinkin, Ghérici Hassaine, Jonathan Perot, Emmanuelle Neumann, Anders A. Jensen, Solène Lefebvre, Pierre-Jean Corringer, Jacques Neyton, Christophe Chipot, Francois Dehez, Guy Schoehn, Hugues Nury

Nature. Author manuscript; available in PMC 2019 Jul 8.

Published in final edited form as: Nature. 2018 Nov 1; 563(7730): 275–279. Published online 2018 Oct 31. doi: 10.1038/s41586-018-0672-3

PMCID:: PMC6614044

Abstract Article PDF–7.6M

Select item 642805014.

The Evf2 ultraconserved enhancer lncRNA functionally and spatially organizes multi-megabase distant genes in developing forebrain

Ivelisse Cajigas, Abhijit Chakraborty, Kelsey R. Swyter, Hao Luo, Monique Bastidas, Maximilliano Nigro, Elizabeth R. Morris, Sean Chen, Michael J. W. VanGompel, David Leib, Sara J. Kohtz, Marco Martina, Sooky Koh, Ferhat Ay, Jhumku D. Kohtz

Mol Cell. Author manuscript; available in PMC 2019 Sep 20.

Published in final edited form as: Mol Cell. 2018 Sep 20; 71(6): 956–972.e9. Published online 2018 Aug 23. doi: 10.1016/j.molcel.2018.07.024