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Items: 1 to 20 of 21

1.
Modulation of tau tubulin kinases (TTBK1 and TTBK2) impacts ciliogenesis
Frances M. Bashore, Ariana B. Marquez, Apirat Chaikuad, Stefanie Howell, Andrea S. Dunn, Alvaro A. Beltran, Jeffery L. Smith, David H. Drewry, Adriana S. Beltran, Alison D. Axtman
Sci Rep. 2023; 13: 6118. Published online 2023 Apr 14. doi: 10.1038/s41598-023-32854-4
PMCID:
PMC10104807
AbstractArticlePDF–3.8M
2.
Loss of RPS27a expression regulates the cell cycle, apoptosis, and proliferation via the RPL11-MDM2-p53 pathway in lung adenocarcinoma cells
Hongyan Li, Hong Zhang, Guomin Huang, Zhitong Bing, Duling Xu, Jiadi Liu, Hongtao Luo, Xiaoli An
J Exp Clin Cancer Res. 2022; 41: 33. Published online 2022 Jan 24. doi: 10.1186/s13046-021-02230-z
PMCID:
PMC8785590
AbstractArticlePDF–9.6M
3.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
4.
Tau‐Tubulin Kinase 1 Expression, Phosphorylation and Co‐Localization with Phospho‐Ser422 Tau in the Alzheimer's Disease Brain
Harald Lund, Richard F. Cowburn, Elin Gustafsson, Kia Strömberg, Anne Svensson, Leif Dahllund, David Malinowsky, Dan Sunnemark
Brain Pathol. 2013 Jul; 23(4): 378–389. Published online 2012 Nov 20. doi: 10.1111/bpa.12001
PMCID:
PMC8029021
AbstractArticlePDF–1.8M
5.
Adult onset pan-neuronal human tau tubulin kinase 1 expression causes severe cerebellar neurodegeneration in mice
Pamela McMillan, Jeanna Wheeler, Rachel E. Gatlin, Laura Taylor, Tim Strovas, Misa Baum, Thomas D. Bird, Caitlin Latimer, C. Dirk Keene, Brian C. Kraemer, Nicole F. Liachko
Acta Neuropathol Commun. 2020; 8: 200. Published online 2020 Nov 23. doi: 10.1186/s40478-020-01073-7
PMCID:
PMC7684928
AbstractArticlePDF–2.7M
6.
Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development
Pu Wang, Feng Yan, Zhijun Li, Yanbao Yu, Scott E. Parnell, Yue Xiong
J Clin Invest. 2019 Oct 1; 129(10): 4393–4407. Published online 2019 Sep 9. doi: 10.1172/JCI129107
PMCID:
PMC6763242
AbstractArticlePDF–12M
7.
Spatial Learning Impairment, Enhanced CDK5/p35 Activity, and Downregulation of NMDA Receptor Expression in Transgenic Mice Expressing Tau-Tubulin Kinase 1
Shinji Sato, Jiqing Xu, Satoshi Okuyama, Lindsey B. Martinez, Shannon M. Walsh, Michael T. Jacobsen, Russell J. Swan, Joshua D. Schlautman, Pawel Ciborowski, Tsuneya Ikezu
J Neurosci. 2008 Dec 31; 28(53): 14511–14521. doi: 10.1523/JNEUROSCI.3417-08.2008
PMCID:
PMC6671237
AbstractArticlePDF–709K
8.
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei
Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck
Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924
PMCID:
PMC6166682
AbstractArticlePDF–3.8M
9.
Pathological phosphorylation of tau and TDP-43 by TTBK1 and TTBK2 drives neurodegeneration
Laura M. Taylor, Pamela J. McMillan, Nicole F. Liachko, Timothy J. Strovas, Bernardino Ghetti, Thomas D. Bird, C. Dirk Keene, Brian C. Kraemer
Mol Neurodegener. 2018; 13: 7. Published online 2018 Feb 6. doi: 10.1186/s13024-018-0237-9
PMCID:
PMC5802059
AbstractArticlePDF–2.5M
10.
A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals Molecular Determinants of Redox Homeostasis and NF-κB Signaling
Ramy H. Malty, Hiroyuki Aoki, Ashwani Kumar, Sadhna Phanse, Shahreen Amin, Qingzhou Zhang, Zoran Minic, Florian Goebels, Gabriel Musso, Zhuoran Wu, Hosam Abou-tok, Michael Meyer, Viktor Deineko, Sandy Kassir, Vishaldeep Sidhu, Matthew Jessulat, Nichollas E. Scott, Xuejian Xiong, James Vlasblom, Bhanu Prasad, Leonard J. Foster, Tiziana Alberio, Barbara Garavaglia, Haiyuan Yu, Gary D. Bader, Ken Nakamura, John Parkinson, Mohan Babu
Cell Syst. Author manuscript; available in PMC 2018 Dec 27.
Published in final edited form as: Cell Syst. 2017 Dec 27; 5(6): 564–577.e12. Published online 2017 Nov 8. doi: 10.1016/j.cels.2017.10.010
PMCID:
PMC5746455
AbstractArticlePDF–3.3M
11.
Roles of tau protein in health and disease
Tong Guo, Wendy Noble, Diane P. Hanger
Acta Neuropathol. 2017; 133(5): 665–704. Published online 2017 Apr 6. doi: 10.1007/s00401-017-1707-9
PMCID:
PMC5390006
AbstractArticlePDF–1.4M
12.
Panorama of ancient metazoan macromolecular complexes
Cuihong Wan, Blake Borgeson, Sadhna Phanse, Fan Tu, Kevin Drew, Greg Clark, Xuejian Xiong, Olga Kagan, Julian Kwan, Alexandr Berzginov, Kyle Chessman, Swati Pal, Graham Cromar, Ophelia Papoulas, Zuyao Ni, Daniel R. Boutz, Snejana Stoilova, Pierre C. Havugimana, Xinghua Guo, Ramy H. Malty, Mihail Sarov, Jack Greenblatt, Mohan Babu, Brent Derry, Elisabeth Tillier, John B. Wallingford, John Parkinson, Edward M. Marcotte, Andrew Emili
Nature. Author manuscript; available in PMC 2016 Sep 26.
Published in final edited form as: Nature. 2015 Sep 17; 525(7569): 339–344. Published online 2015 Sep 7. doi: 10.1038/nature14877
PMCID:
PMC5036527
AbstractArticlePDF–4.7M
13.
De novo variants in sporadic cases of childhood onset schizophrenia
Amirthagowri Ambalavanan, Simon L Girard, Kwangmi Ahn, Sirui Zhou, Alexandre Dionne-Laporte, Dan Spiegelman, Cynthia V Bourassa, Julie Gauthier, Fadi F Hamdan, Lan Xiong, Patrick A Dion, Ridha Joober, Judith Rapoport, Guy A Rouleau
Eur J Hum Genet. 2016 Jun; 24(6): 944–948. Published online 2015 Oct 28. doi: 10.1038/ejhg.2015.218
PMCID:
PMC4867457
AbstractArticlePDF–680K
14.
TTBK2 with EB1/3 regulates microtubule dynamics in migrating cells through KIF2A phosphorylation
Takashi Watanabe, Mai Kakeno, Toshinori Matsui, Ikuko Sugiyama, Nariko Arimura, Kenji Matsuzawa, Aya Shirahige, Fumiyoshi Ishidate, Tomoki Nishioka, Shinichiro Taya, Mikio Hoshino, Kozo Kaibuchi
J Cell Biol. 2015 Aug 31; 210(5): 737–751. doi: 10.1083/jcb.201412075
PMCID:
PMC4555816
AbstractArticlePDF–3.4M
15.
Phosphorylation of Synaptic Vesicle Protein 2A at Thr84 by Casein Kinase 1 Family Kinases Controls the Specific Retrieval of Synaptotagmin-1
Ning Zhang, Sarah L. Gordon, Maximilian J. Fritsch, Noor Esoof, David G. Campbell, Robert Gourlay, Srikannathasan Velupillai, Thomas Macartney, Mark Peggie, Daan M.F. van Aalten, Michael A. Cousin, Dario R. Alessi
J Neurosci. 2015 Feb 11; 35(6): 2492–2507. doi: 10.1523/JNEUROSCI.4248-14.2015
PMCID:
PMC4323530
AbstractArticlePDF–3.6M
16.
The Tau Tubulin Kinases TTBK1/2 Promote Accumulation of Pathological TDP-43
Nicole F. Liachko, Pamela J. McMillan, Timothy J. Strovas, Elaine Loomis, Lynne Greenup, Jill R. Murrell, Bernardino Ghetti, Murray A. Raskind, Thomas J. Montine, Thomas D. Bird, James B. Leverenz, Brian C. Kraemer
PLoS Genet. 2014 Dec; 10(12): e1004803. Published online 2014 Dec 4. doi: 10.1371/journal.pgen.1004803
PMCID:
PMC4256087
AbstractArticlePDF–1.4M
17.
The structure of human tau-tubulin kinase 1 both in the apo form and in complex with an inhibitor
Susan E. Kiefer, ChiehYing J. Chang, S. Roy Kimura, Mian Gao, Dianlin Xie, Yaqun Zhang, Guifen Zhang, Martin B. Gill, Harold Mastalerz, Lorin A. Thompson, Angela M. Cacace, Steven Sheriff
Acta Crystallogr F Struct Biol Commun. 2014 Feb 1; 70(Pt 2): 173–181. Published online 2014 Jan 21. doi: 10.1107/S2053230X14000144
PMCID:
PMC3936456
AbstractArticlePDF–1.4M
18.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
19.
Large-scale mapping of human protein–protein interactions by mass spectrometry
Rob M Ewing, Peter Chu, Fred Elisma, Hongyan Li, Paul Taylor, Shane Climie, Linda McBroom-Cerajewski, Mark D Robinson, Liam O'Connor, Michael Li, Rod Taylor, Moyez Dharsee, Yuen Ho, Adrian Heilbut, Lynda Moore, Shudong Zhang, Olga Ornatsky, Yury V Bukhman, Martin Ethier, Yinglun Sheng, Julian Vasilescu, Mohamed Abu-Farha, Jean-Philippe Lambert, Henry S Duewel, Ian I Stewart, Bonnie Kuehl, Kelly Hogue, Karen Colwill, Katharine Gladwish, Brenda Muskat, Robert Kinach, Sally-Lin Adams, Michael F Moran, Gregg B Morin, Thodoros Topaloglou, Daniel Figeys
Mol Syst Biol. 2007; 3: 89. Published online 2007 Mar 13. doi: 10.1038/msb4100134
PMCID:
PMC1847948
AbstractArticlePDF–440K
20.
The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)
Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504
Correction in:
Genome Res. 2006 Jun; 16(6): 804.
PMCID:
PMC528928
AbstractArticlePDF–140K

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