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Select item 106472201.

Candidate Genes for IgA Nephropathy in Pediatric Patients: Exome-Wide Association Study

Anastasiia A. Buianova, Mariia V. Proskura, Valery V. Cheranev, Vera A. Belova, Anna O. Shmitko, Anna S. Pavlova, Iuliia A. Vasiliadis, Oleg N. Suchalko, Denis V. Rebrikov, Edita K. Petrosyan, Dmitriy O. Korostin

Int J Mol Sci. 2023 Nov; 24(21): 15984. Published online 2023 Nov 5. doi: 10.3390/ijms242115984

PMCID:: PMC10647220

Abstract Article PDF–3.7M

Select item 102374222.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 101516153.

Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell

Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low

Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120

PMCID:: PMC10151615

Abstract Article PDF–2.9M

Select item 81650304.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 58982665.

ZFP36L2 is a cell cycle-regulated CCCH protein necessary for DNA lesion-induced S-phase arrest

Aya Noguchi, Shungo Adachi, Naoto Yokota, Tomohisa Hatta, Tohru Natsume, Hiroyuki Kawahara

Biol Open. 2018 Mar 15; 7(3): bio031575. Published online 2018 Feb 15. doi: 10.1242/bio.031575

PMCID:: PMC5898266

Abstract Article PDF–3.4M

Select item 58269266.

VIRMA mediates preferential m⁶A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation

Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu

Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0

PMCID:: PMC5826926

Abstract Article PDF–2.3M

Select item 55316117.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 48266148.

?F508 CFTR interactome remodeling promotes rescue of Cystic Fibrosis

Sandra Pankow, Casimir Bamberger, Diego Calzolari, Salvador Martínez-Bartolomé, Mathieu Lavallée-Adam, William E. Balch, John R. Yates, III

Nature. Author manuscript; available in PMC 2016 May 30.

Published in final edited form as: Nature. 2015 Dec 24; 528(7583): 510–516. Published online 2015 Nov 30. doi: 10.1038/nature15729

PMCID:: PMC4826614

Abstract Article PDF–5.7M

Select item 46172119.

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2016 Jul 16.

Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043

PMCID:: PMC4617211

Abstract Article PDF–2.2M

Select item 461467910.

The melanoma-associated antigen 1 (MAGEA1) protein stimulates the E3 ubiquitin-ligase activity of TRIM31 within a TRIM31-MAGEA1-NSE4 complex

Lucie Kozakova, Lucie Vondrova, Karel Stejskal, Panagoula Charalabous, Peter Kolesar, Alan R Lehmann, Stjepan Uldrijan, Christopher M Sanderson, Zbynek Zdrahal, Jan J Palecek

Cell Cycle. 2015 Mar 15; 14(6): 920–930. Published online 2015 Jan 15. doi: 10.1080/15384101.2014.1000112

PMCID:: PMC4614679

Abstract Article PDF–558K

Select item 456891911.

Cardiac Na_v1.5 is modulated by ubiquitin protein ligase E3 component n-recognin UBR3 and 6

Chunxia Zhao, Lijie Wang, Xiue Ma, Weidong Zhu, Lei Yao, Yingyu Cui, Yi Liu, Jun Li, Xingqun Liang, Yunfu Sun, Li Li, Yi-Han Chen

J Cell Mol Med. 2015 Sep; 19(9): 2143–2152. Published online 2015 Jun 7. doi: 10.1111/jcmm.12588

PMCID:: PMC4568919

Abstract Article PDF–669K

Select item 434998612.

KCMF1 (potassium channel modulatory factor 1) Links RAD6 to UBR4 (ubiquitin N-recognin domain-containing E3 ligase 4) and Lysosome-Mediated Degradation

Jenny H. Hong, Lilia Kaustov, Etienne Coyaud, Tharan Srikumar, Janet Wan, Cheryl Arrowsmith, Brian Raught

Mol Cell Proteomics. 2015 Mar; 14(3): 674–685. Published online 2015 Jan 12. doi: 10.1074/mcp.M114.042168

PMCID:: PMC4349986

Abstract Article PDF–3.4M

Select item 410402713.

Cytosolic Quality Control of Mislocalized Proteins Requires RNF126 Recruitment to Bag6

Monica C. Rodrigo-Brenni, Erik Gutierrez, Ramanujan S. Hegde

Mol Cell. 2014 Jul 17; 55(2): 227–237. doi: 10.1016/j.molcel.2014.05.025

PMCID:: PMC4104027

Abstract Article

Select item 339495214.

Systematic Analysis of Dimeric E3-RING Interactions Reveals Increased Combinatorial Complexity in Human Ubiquitination Networks

Jonathan Woodsmith, Robert C. Jenn, Chris M. Sanderson

Mol Cell Proteomics. 2012 Jul; 11(7): M111.016162. Published online 2012 Apr 5. doi: 10.1074/mcp.M111.016162

PMCID:: PMC3394952

Abstract Article PDF–3.3M

Select item 325813615.

Ubiquitin ligase UBR3 regulates cellular levels of the essential DNA repair protein APE1 and is required for genome stability

Cornelia Meisenberg, Phillip S. Tait, Irina I. Dianova, Katherine Wright, Mariola J. Edelmann, Nicola Ternette, Takafumi Tasaki, Benedikt M. Kessler, Jason L. Parsons, Yong Tae Kwon, Grigory L. Dianov

Nucleic Acids Res. 2012 Jan; 40(2): 701–711. Published online 2011 Sep 20. doi: 10.1093/nar/gkr744

PMCID:: PMC3258136

Abstract Article PDF–3.7M

Select item 317805916.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 315148717.

Alternative Ubiquitin Activation/Conjugation Cascades Interact with N-end rule Ubiquitin Ligases to Control Degradation of RGS Proteins

Peter C.W. Lee, Mathew E. Sowa, Steven P. Gygi, J. Wade Harper

Mol Cell. Author manuscript; available in PMC 2012 Aug 5.

Published in final edited form as: Mol Cell. 2011 Aug 5; 43(3): 392–405. doi: 10.1016/j.molcel.2011.05.034

PMCID:: PMC3151487

Abstract Article PDF–2.6M

Select item 276528018.

Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network

Gabriel Markson, Christina Kiel, Russell Hyde, Stephanie Brown, Panagoula Charalabous, Anja Bremm, Jennifer Semple, Jonathan Woodsmith, Simon Duley, Kourosh Salehi-Ashtiani, Marc Vidal, David Komander, Luis Serrano, Paul Lehner, Christopher M. Sanderson

Genome Res. 2009 Oct; 19(10): 1905–1911. doi: 10.1101/gr.093963.109

PMCID:: PMC2765280

Abstract Article PDF–425K

Select item 222443719.

Human Immunodeficiency Virus Type 1 Vpr Links Proteasomal Degradation and Checkpoint Activation

Jason L. DeHart, Vicente Planelles

J Virol. 2008 Feb; 82(3): 1066–1072. Published online 2007 Sep 12. doi: 10.1128/JVI.01628-07

PMCID:: PMC2224437

Article PDF–222K

Select item 182072020.

HIV-1 Vpr function is mediated by interaction with the damage-specific DNA-binding protein DDB1

Bärbel Schröfelbauer, Yoshiyuki Hakata, Nathaniel R. Landau

Proc Natl Acad Sci U S A. 2007 Mar 6; 104(10): 4130–4135. Published online 2007 Feb 28. doi: 10.1073/pnas.0610167104

PMCID:: PMC1820720

Abstract Article PDF–500K

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