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Items: 1 to 20 of 131

1.
PML::RARA and GATA2 proteins interact via DNA templates to induce aberrant self-renewal in mouse and human hematopoietic cells
Casey D. S. Katerndahl, Olivia R. S. Rogers, Ryan B. Day, Ziheng Xu, Nichole M. Helton, Sai Mukund Ramakrishnan, Christopher A. Miller, Timothy J. Ley
Proc Natl Acad Sci U S A. 2024 Apr 30; 121(18): e2317690121. Published online 2024 Apr 22. doi: 10.1073/pnas.2317690121
PMCID:
PMC11067031
AbstractArticlePDF–7.2M
2.
Y chromosome damage underlies testicular abnormalities in ATR-X syndrome
Nayla Y. León, Thanh Nha Uyen Le, Andrew Garvie, Lee H. Wong, Stefan Bagheri-Fam, Vincent R. Harley
iScience. 2024 May 17; 27(5): 109629. Published online 2024 Mar 28. doi: 10.1016/j.isci.2024.109629
PMCID:
PMC11015497
AbstractArticlePDF–4.6M
3.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
4.
The Paget's disease of bone risk gene PML is a negative regulator of osteoclast differentiation and bone resorption
Sachin Wani, Anna Daroszewska, Donald M. Salter, Rob J. van ‘t Hof, Stuart H. Ralston, Omar M. E. Albagha
Dis Model Mech. 2022 Apr 1; 15(4): dmm049318. Published online 2022 Apr 26. doi: 10.1242/dmm.049318
PMCID:
PMC9066519
AbstractArticle
5.
Promyelocytic leukemia protein targets MK2 to promote cytotoxicity
I‐Ting Chen, Hsiao‐Chi Chen, Yu‐Hsun Lo, Peng‐Yeh Lai, Fu‐Yi Hsieh, Yung‐Hsuan Wu, Hsiu‐Ming Shih, Ming‐Zong Lai
EMBO Rep. 2021 Dec 6; 22(12): e52254. Published online 2021 Oct 11. doi: 10.15252/embr.202052254
PMCID:
PMC8647022
AbstractArticlePDF–3.1M
6.
Robust p53 stabilization is dispensable for its activation and tumor suppressor function
Ning Kon, Michael Churchill, Huan Li, Siddhartha Mukherjee, James J. Manfredi, Wei Gu
Cancer Res. Author manuscript; available in PMC 2021 Aug 15.
Published in final edited form as: Cancer Res. 2021 Feb 15; 81(4): 935–944. Published online 2020 Dec 15. doi: 10.1158/0008-5472.CAN-20-1804
PMCID:
PMC8026563
AbstractArticlePDF–1.5M
7.
Usp11 controls cortical neurogenesis and neuronal migration through Sox11 stabilization
Shang-Yin Chiang, Hsin-Chieh Wu, Shu-Yu Lin, Hsin-Yi Chen, Chia-Fang Wang, Nai-Hsing Yeh, Jou-Ho Shih, Yi-Shuian Huang, Hung-Chih Kuo, Shen-Ju Chou, Ruey-Hwa Chen
Sci Adv. 2021 Feb; 7(7): eabc6093. Published online 2021 Feb 12. doi: 10.1126/sciadv.abc6093
PMCID:
PMC7880594
AbstractArticlePDF–6.1M
8.
JAK2V617F myeloproliferative neoplasm eradication by a novel interferon/arsenic therapy involves PML
Tracy Dagher, Nabih Maslah, Valérie Edmond, Bruno Cassinat, William Vainchenker, Stéphane Giraudier, Florence Pasquier, Emmanuelle Verger, Michiko Niwa-Kawakita, Valérie Lallemand-Breitenbach, Isabelle Plo, Jean-Jacques Kiladjian, Jean-Luc Villeval, Hugues de Thé
J Exp Med. 2021 Feb 1; 218(2): e20201268. Published online 2020 Oct 19. doi: 10.1084/jem.20201268
PMCID:
PMC7579737
AbstractArticlePDF–3.9M
9.
An aberrant SREBP-dependent lipogenic program promotes metastatic prostate cancer
Ming Chen, Jiangwen Zhang, Katia Sampieri, John G. Clohessy, Lourdes Mendez, Enrique Gonzalez-Billalabeitia, Xue-Song Liu, Yu-Ru Lee, Jacqueline Fung, Jesse M. Katon, Archita Venugopal Menon, Kaitlyn A. Webster, Christopher Ng, Maria Dilia Palumbieri, Moussa S. Diolombi, Susanne B. Breitkopf, Julie Teruya-Feldstein, Sabina Signoretti, Roderick T. Bronson, John M. Asara, Mireia Castillo-Martin, Carlos Cordon-Cardo, Pier Paolo Pandolfi
Nat Genet. Author manuscript; available in PMC 2019 Aug 29.
Published in final edited form as: Nat Genet. 2018 Feb; 50(2): 206–218. Published online 2018 Jan 15. doi: 10.1038/s41588-017-0027-2
PMCID:
PMC6714980
AbstractArticlePDF–1.6M
10.
Loss of SET reveals both the p53-dependent and the p53-independent functions in vivo
Ning Kon, Donglai Wang, Wei Gu
Cell Death Dis. 2019 Mar; 10(3): 237. Published online 2019 Mar 11. doi: 10.1038/s41419-019-1484-6
PMCID:
PMC6411979
AbstractArticlePDF–2.3M
11.
Pml nuclear body disruption cooperates in APL pathogenesis and impairs DNA damage repair pathways in mice
Edwige Voisset, Eva Moravcsik, Eva W. Stratford, Amie Jaye, Christopher J. Palgrave, Robert K. Hills, Paolo Salomoni, Scott C. Kogan, Ellen Solomon, David Grimwade
Blood. 2018 Feb 8; 131(6): 636–648. Prepublished online 2017 Nov 30. doi: 10.1182/blood-2017-07-794784
PMCID:
PMC5805489
AbstractArticle
12.
A Functional Screen to Identify Novel Effectors of Hematopoietic Stem Cell Activity
Eric Deneault, Sonia Cellot, Amélie Faubert, Jean-Philippe Laverdure, Mélanie Fréchette, Jalila Chagraoui, Nadine Mayotte, Martin Sauvageau, Stephen B. Ting, Guy Sauvageau
Cell. Author manuscript; available in PMC 2018 Jan 16.
Published in final edited form as: Cell. 2009 Apr 17; 137(2): 369–379. doi: 10.1016/j.cell.2009.03.026
PMCID:
PMC5770201
AbstractArticlePDF–1.6M
13.
A non-cell-autonomous role for Pml in the maintenance of leukemia from the niche
Jlenia Guarnerio, Lourdes Maria Mendez, Noboru Asada, Archita Venugopal Menon, Jacqueline Fung, Kelsey Berry, Paul S. Frenette, Keisuke Ito, Pier Paolo Pandolfi
Nat Commun. 2018; 9: 66. Published online 2018 Jan 4. doi: 10.1038/s41467-017-02427-x
PMCID:
PMC5754357
AbstractArticlePDF–2.5M
14.
PML is a ROS sensor activating p53 upon oxidative stress
Michiko Niwa-Kawakita, Omar Ferhi, Hassane Soilihi, Morgane Le Bras, Valérie Lallemand-Breitenbach, Hugues de Thé
J Exp Med. 2017 Nov 6; 214(11): 3197–3206. doi: 10.1084/jem.20160301
PMCID:
PMC5679165
AbstractArticlePDF–1.9M
15.
Dual regulation of Stat1 and Stat3 by the tumor suppressor protein PML contributes to interferon α-mediated inhibition of angiogenesis
Kuo-Sheng Hsu, Xuan Zhao, Xiwen Cheng, Dongyin Guan, Ganapati H. Mahabeleshwar, Yu Liu, Ernest Borden, Mukesh K. Jain, Hung-Ying Kao
J Biol Chem. 2017 Jun 16; 292(24): 10048–10060. Published online 2017 Apr 21. doi: 10.1074/jbc.M116.771071
PMCID:
PMC5473212
AbstractArticlePDF–2.4M
16.
PML protein organizes heterochromatin domains where it regulates histone H3.3 deposition by ATRX/DAXX
Erwan Delbarre, Kristina Ivanauskiene, Jane Spirkoski, Akshay Shah, Kristin Vekterud, Jan Øivind Moskaug, Stig Ove Bøe, Lee H. Wong, Thomas Küntziger, Philippe Collas
Genome Res. 2017 Jun; 27(6): 913–921. doi: 10.1101/gr.215830.116
PMCID:
PMC5453325
AbstractArticlePDF–1.0M
17.
Myogenic differentiation triggers PML nuclear body loss and DAXX relocalization to chromocentres
Jayme Salsman, Lindsy M Rapkin, Nandini N Margam, Roy Duncan, David P Bazett-Jones, Graham Dellaire
Cell Death Dis. 2017 Mar; 8(3): e2724. Published online 2017 Mar 30. doi: 10.1038/cddis.2017.151
PMCID:
PMC5386546
AbstractArticlePDF–4.3M
18.
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function
Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang
Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626
PMCID:
PMC5381226
AbstractArticlePDF–1.4M
19.
Manipulating PML SUMOylation via Silencing UBC9 and RNF4 Regulates Cardiac Fibrosis
Yu Liu, Dan Zhao, Fang Qiu, Ling-Ling Zhang, Shang-Kun Liu, Yuan-Yuan Li, Mei-Tong Liu, Di Wu, Jia-Xin Wang, Xiao-Qing Ding, Yan-Xin Liu, Chang-Jiang Dong, Xiao-Qi Shao, Bao-Feng Yang, Wen-Feng Chu
Mol Ther. 2017 Mar 1; 25(3): 666–678. Published online 2017 Jan 28. doi: 10.1016/j.ymthe.2016.12.021
PMCID:
PMC5363217
AbstractArticlePDF–4.5M
20.
Latency Entry of Herpes Simplex Virus 1 Is Determined by the Interaction of Its Genome with the Nuclear Environment
Mohamed Ali Maroui, Aleth Callé, Camille Cohen, Nathalie Streichenberger, Pascale Texier, Julie Takissian, Antoine Rousseau, Nolwenn Poccardi, Jérémy Welsch, Armelle Corpet, Laurent Schaeffer, Marc Labetoulle, Patrick Lomonte
PLoS Pathog. 2016 Sep; 12(9): e1005834. Published online 2016 Sep 12. doi: 10.1371/journal.ppat.1005834
PMCID:
PMC5019400
AbstractArticlePDF–14M

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