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Select item 72501641.

MEF2c-dependent downregulation of Myocilin mediates cancer-induced muscle wasting and associates with cachexia in cancer patients

Sarah M. Judge, Michael R. Deyhle, Daria Neyroud, Rachel L. Nosacka, Andrew C. D’Lugos, Miles E. Cameron, Ravneet S. Vohra, Ashley J. Smuder, Brandon M. Roberts, Chandler S. Callaway, Patrick W. Underwood, Stephen M. Chrzanowski, Abhinandan Batra, Meghan E. Murphy, Jonathan D. Heaven, Glenn A. Walter, Jose G. Trevino, Andrew R. Judge

Cancer Res. Author manuscript; available in PMC 2020 Nov 1.

Published in final edited form as: Cancer Res. 2020 May 1; 80(9): 1861–1874. Published online 2020 Mar 4. doi: 10.1158/0008-5472.CAN-19-1558

PMCID:: PMC7250164

Abstract Article PDF–2.3M

Select item 68151012.

Differential misfolding properties of glaucoma-associated olfactomedin domains from human and mouse

Athéna C. Patterson-Orazem, Shannon E. Hill, Yiming Wang, Iramofu M. Dominic, Carol K. Hall, Raquel L. Lieberman

Biochemistry. Author manuscript; available in PMC 2020 Apr 2.

Published in final edited form as: Biochemistry. 2019 Apr 2; 58(13): 1718–1727. Published online 2019 Mar 12. doi: 10.1021/acs.biochem.8b01309

PMCID:: PMC6815101

Abstract Article PDF–1.7M

Select item 66748793.

Expression of Mutated Mouse Myocilin Induces Open-Angle Glaucoma in Transgenic Mice

Vladimir Senatorov, Irina Malyukova, Robert Fariss, Eric F. Wawrousek, Srividya Swaminathan, Shyam K. Sharan, Stanislav Tomarev

J Neurosci. 2006 Nov 15; 26(46): 11903–11914. doi: 10.1523/JNEUROSCI.3020-06.2006

PMCID:: PMC6674879

Abstract Article PDF–1.6M

Select item 66024074.

Altered keratinocyte differentiation is an early driver of keratin mutation-based palmoplantar keratoderma

Abigail G Zieman, Brian G Poll, Jingqun Ma, Pierre A Coulombe

Hum Mol Genet. 2019 Jul 1; 28(13): 2255–2270. Published online 2019 Mar 20. doi: 10.1093/hmg/ddz050

PMCID:: PMC6602407

Abstract Article PDF–3.5M

Select item 63114995.

Binding of a glaucoma-associated myocilin variant to the αB-crystallin chaperone impedes protein clearance in trabecular meshwork cells

Jeffrey M. Lynch, Bing Li, Parvaneh Katoli, Chuanxi Xiang, Barrett Leehy, Nalini Rangaswamy, Veronica Saenz-Vash, Y. Karen Wang, Hong Lei, Thomas B. Nicholson, Erik Meredith, Dennis S. Rice, Ganesh Prasanna, Amy Chen

J Biol Chem. 2018 Dec 28; 293(52): 20137–20156. Published online 2018 Nov 2. doi: 10.1074/jbc.RA118.004325

PMCID:: PMC6311499

Abstract Article PDF–4.6M

Select item 62180656.

Mutant myocilin impacts sarcomere ultrastructure in mouse gastrocnemius muscle

Jeffrey M. Lynch, Andrew J. Dolman, Chenying Guo, Katie Dolan, Chuanxi Xiang, Samir Reda, Bing Li, Ganesh Prasanna

PLoS One. 2018; 13(11): e0206801. Published online 2018 Nov 5. doi: 10.1371/journal.pone.0206801

PMCID:: PMC6218065

Abstract Article PDF–2.4M

Select item 58635287.

Lmx1b is required for murine trabecular meshwork formation and for maintenance of corneal transparency

Pu Liu, Randy L. Johnson

Dev Dyn. Author manuscript; available in PMC 2018 Mar 22.

Published in final edited form as: Dev Dyn. 2010 Aug; 239(8): 2161–2171. doi: 10.1002/dvdy.22347

PMCID:: PMC5863528

Abstract Article PDF–1.7M

Select item 56447068.

Myocilin Regulates Metalloprotease 2 Activity Through Interaction With TIMP3

Myung Kuk Joe, Raquel L. Lieberman, Naoki Nakaya, Stanislav I. Tomarev

Invest Ophthalmol Vis Sci. 2017 Oct; 58(12): 5308–5318. doi: 10.1167/iovs.16-20336

PMCID:: PMC5644706

Abstract Article PDF–1.1M

Select item 53976789.

Dexamethasone-Induced Ocular Hypertension in Mice: Effects of Myocilin and Route of Administration

Gaurang C. Patel, Tien N. Phan, Prabhavathi Maddineni, Ramesh B. Kasetti, J. Cameron Millar, Abbot F. Clark, Gulab S. Zode

Am J Pathol. 2017 Apr; 187(4): 713–723. doi: 10.1016/j.ajpath.2016.12.003

PMCID:: PMC5397678

Abstract Article PDF–1.5M

Select item 510256610.

Expression of Mutant Myocilin Induces Abnormal Intracellular Accumulation of Selected Extracellular Matrix Proteins in the Trabecular Meshwork

Ramesh B. Kasetti, Tien N. Phan, J. Cameron Millar, Gulab S. Zode

Invest Ophthalmol Vis Sci. 2016 Nov; 57(14): 6058–6069. doi: 10.1167/iovs.16-19610

PMCID:: PMC5102566

Abstract Article PDF–3.4M

Select item 444788911.

Mutated myocilin and heterozygous Sod2 deficiency act synergistically in a mouse model of open-angle glaucoma

Myung Kuk Joe, Naoki Nakaya, Mones Abu-Asab, Stanislav I. Tomarev

Hum Mol Genet. 2015 Jun 15; 24(12): 3322–3334. Published online 2015 Mar 3. doi: 10.1093/hmg/ddv082

PMCID:: PMC4447889

Abstract Article PDF–2.0M

Select item 431955912.

A high resolution spatiotemporal atlas of gene expression of the developing mouse brain

Carol L. Thompson, Lydia Ng, Vilas Menon, Salvador Martinez, Chang-Kyu Lee, Katie Glattfelder, Susan M. Sunkin, Alex Henry, Christopher Lau, Chinh Dang, Raquel Garcia-Lopez, Almudena Martinez-Ferre, Ana Pombero, John L.R. Rubenstein, Wayne B. Wakeman, John Hohmann, Nick Dee, Andrew J. Sodt, Rob Young, Kimberly Smith, Thuc-Nghi Nguyen, Jolene Kidney, Leonard Kuan, Andreas Jeromin, Ajamete Kaykas, Jeremy Miller, Damon Page, Geri Orta, Amy Bernard, Zackery Riley, Simon Smith, Paul Wohnoutka, Mike Hawrylycz, Luis Puelles, Allan R. Jones

Neuron. Author manuscript; available in PMC 2015 Jul 16.

Published in final edited form as: Neuron. 2014 Jul 16; 83(2): 309–323. Published online 2014 Jun 19. doi: 10.1016/j.neuron.2014.05.033