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Select item 107883401.

Force-induced Caspase-1-dependent pyroptosis regulates orthodontic tooth movement

Liyuan Chen, Huajie Yu, Zixin Li, Yu Wang, Shanshan Jin, Min Yu, Lisha Zhu, Chengye Ding, Xiaolan Wu, Tianhao Wu, Chunlei Xun, Yanheng Zhou, Danqing He, Yan Liu

Int J Oral Sci. 2024; 16: 3. Published online 2024 Jan 15. doi: 10.1038/s41368-023-00268-7

PMCID:: PMC10788340

Abstract Article PDF–8.3M

Select item 102833442.

Role of Proinflammatory Cytokines IL-18 and IL-1β in Bleomycin-Induced Lung Injury in Humans and Mice

Tomoaki Hoshino, Masaki Okamoto, Yuki Sakazaki, Seiya Kato, Howard A. Young, Hisamichi Aizawa

Am J Respir Cell Mol Biol. Author manuscript; available in PMC 2023 Jun 21.

Published in final edited form as: Am J Respir Cell Mol Biol. 2009 Dec; 41(6): 661–670. Published online 2009 Mar 5. doi: 10.1165/rcmb.2008-0182OC

PMCID:: PMC10283344

Abstract Article PDF–1.4M

Select item 95270893.

High Ca²⁺ Influx During Traumatic Brain Injury Leads to Caspase-1-Dependent Neuroinflammation and Cell Death

P. M. Abdul-Muneer, Mathew Long, Adriano Andrea Conte, Vijayalakshmi Santhakumar, Bryan J. Pfister

Mol Neurobiol. Author manuscript; available in PMC 2022 Oct 2.

Published in final edited form as: Mol Neurobiol. 2017 Aug; 54(6): 3964–3975. Published online 2016 Jun 11. doi: 10.1007/s12035-016-9949-4

PMCID:: PMC9527089

Abstract Article PDF–1.4M

Select item 93448164.

Activation of adenosine A3 receptor attenuates progression of osteoarthritis through inhibiting the NLRP3/caspase‐1/GSDMD induced signalling

Hui Bai, Zhiheng Zhang, Lin Liu, Xinyu Wang, Xiaopeng Song, Li Gao

J Cell Mol Med. 2022 Aug; 26(15): 4230–4243. Published online 2022 Jun 30. doi: 10.1111/jcmm.17438

PMCID:: PMC9344816

Abstract Article PDF–15M

Select item 72727455.

cAMP signaling primes lung endothelial cells to activate caspase-1 during Pseudomonas aeruginosa infection

Phoibe Renema, Kierra S. Hardy, Nicole Housley, Grace Dunbar, Naga Annamdevula, Andrea Britain, Domenico Spadafora, Silas Leavesley, Thomas Rich, Jonathon P. Audia, Diego F. Alvarez

Am J Physiol Lung Cell Mol Physiol. 2020 May 1; 318(5): L1074–L1083. Published online 2020 Mar 18. doi: 10.1152/ajplung.00185.2019

PMCID:: PMC7272745

Abstract Article

Select item 66705836.

A Molecular Platform in Neurons Regulates Inflammation after Spinal Cord Injury

Juan Pablo de Rivero Vaccari, George Lotocki, Alex E. Marcillo, W. Dalton Dietrich, Robert W. Keane

J Neurosci. 2008 Mar 26; 28(13): 3404–3414. doi: 10.1523/JNEUROSCI.0157-08.2008

PMCID:: PMC6670583

Abstract Article PDF–826K

Select item 55152297.

The NALP1 inflammasome controls cytokine production and nociception in a rat fracture model of complex regional pain syndrome

Wen-Wu Li, Tian-Zhi Guo, Deyong Liang, Xiaoyou Shi, Tzuping Wei, Wade S. Kingery, J. David Clark

Pain. Author manuscript; available in PMC 2017 Jul 18.

Published in final edited form as: Pain. 2009 Dec 15; 147(1-3): 277–286. Published online 2009 Oct 22. doi: 10.1016/j.pain.2009.09.032

PMCID:: PMC5515229

Abstract Article PDF–1.2M

Select item 48565358.

Molecular basis of caspase-1 polymerization and its inhibition by a novel capping mechanism

Alvin Lu, Yang Li, Florian I. Schmidt, Qian Yin, Shuobing Chen, Tian-Min Fu, Alexander B. Tong, Hidde L. Ploegh, Youdong Mao, Hao Wu

Nat Struct Mol Biol. Author manuscript; available in PMC 2016 Oct 4.

Published in final edited form as: Nat Struct Mol Biol. 2016 May; 23(5): 416–425. Published online 2016 Apr 4. doi: 10.1038/nsmb.3199

PMCID:: PMC4856535

Abstract Article PDF–5.0M

Select item 46498409.

Caspase-1 cleavage of transcription factor GATA4 and regulation of cardiac cell fate

A Aries, J Whitcomb, W Shao, H Komati, M Saleh, M Nemer

Cell Death Dis. 2014 Dec; 5(12): e1566. Published online 2014 Dec 11. doi: 10.1038/cddis.2014.524

PMCID:: PMC4649840

Abstract Article PDF–1.7M

Select item 413085310.

Caspase-1 inhibition alleviates acute renal injury in rats with severe acute pancreatitis

Xiao-Hua Zhang, Min-Li Li, Bin Wang, Mei-Xia Guo, Ren-Min Zhu

World J Gastroenterol. 2014 Aug 14; 20(30): 10457–10463. Published online 2014 Aug 14. doi: 10.3748/wjg.v20.i30.10457

PMCID:: PMC4130853

Abstract Article PDF–1.2M

Select item 406598811.

Therapeutic effects of Caspase-1 inhibitors on acute lung injury in experimental severe acute pancreatitis

Xiao-Hua Zhang, Ren-Min Zhu, Wen-An Xu, Hai-Jun Wan, Heng Lu

World J Gastroenterol. 2007 Jan 28; 13(4): 623–627. Published online 2007 Jan 28. doi: 10.3748/wjg.v13.i4.623

PMCID:: PMC4065988

Abstract Article PDF–784K

Select item 401764012.

NLRP6 inflammasome orchestrates the colonic host-microbial interface by regulating goblet cell mucus secretion

Marta Wlodarska, Christoph A. Thaiss, Roni Nowarski, Jorge Henao-Mejia, Jian-Ping Zhang, Eric M. Brown, Gad Frankel, Maayan Levy, Meirav N. Katz, William M. Philbrick, Eran Elinav, B. Brett Finlay, Richard A. Flavell

Cell. Author manuscript; available in PMC 2014 Aug 27.

Published in final edited form as: Cell. 2014 Feb 27; 156(5): 1045–1059. doi: 10.1016/j.cell.2014.01.026

PMCID:: PMC4017640

Abstract Article PDF–22M

Select item 400006613.

Unified Polymerization Mechanism for the Assembly of ASC-dependent Inflammasomes

Alvin Lu, VenkatGiri Magupalli, Jianbin Ruan, Qian Yin, Maninjay K. Atianand, Matthijn Vos, Gunnar F. Schröder, Katherine A. Fitzgerald, Hao Wu, Edward H. Egelman

Cell. Author manuscript; available in PMC 2015 Mar 13.

Published in final edited form as: Cell. 2014 Mar 13; 156(6): 1193–1206. doi: 10.1016/j.cell.2014.02.008

PMCID:: PMC4000066

Abstract Article PDF–4.9M

Select item 397485714.

A Highly Conserved Toxo1 Haplotype Directs Resistance to Toxoplasmosis and Its Associated Caspase-1 Dependent Killing of Parasite and Host Macrophage

Pierre Cavailles, Pierre Flori, Olivier Papapietro, Cordelia Bisanz, Dominique Lagrange, Ludovic Pilloux, Céline Massera, Sara Cristinelli, Delphine Jublot, Olivier Bastien, Corinne Loeuillet, Delphine Aldebert, Bastien Touquet, Gilbert J. Fournié, Marie France Cesbron-Delauw

PLoS Pathog. 2014 Apr; 10(4): e1004005. Published online 2014 Apr 3. doi: 10.1371/journal.ppat.1004005

PMCID:: PMC3974857

Abstract Article PDF–1.5M

Select item 397359415.

Mizoribine Ameliorates Renal Injury and Hypertension along with the Attenuation of Renal Caspase-1 Expression in Aldosterone-Salt-Treated Rats

Toshiki Doi, Shigehiro Doi, Ayumu Nakashima, Toshinori Ueno, Yukio Yokoyama, Nobuoki Kohno, Takao Masaki

PLoS One. 2014; 9(4): e93513. Published online 2014 Apr 2. doi: 10.1371/journal.pone.0093513

PMCID:: PMC3973594

Abstract Article PDF–1.3M

Select item 368376816.

CCT chaperonin complex is required for efficient delivery of anthrax toxin into the cytosol of host cells

Louise H. Slater, Erik C. Hett, Anne E. Clatworthy, Kevin G. Mark, Deborah T. Hung

Proc Natl Acad Sci U S A. 2013 Jun 11; 110(24): 9932–9937. Published online 2013 May 28. doi: 10.1073/pnas.1302257110

PMCID:: PMC3683768

Abstract Article PDF–488K

Select item 365928517.

Intracellular Interleukin-1 Receptor 2 Binding Prevents Cleavage and Activity of Interleukin-1α, Controlling Necrosis-Induced Sterile Inflammation

Yue Zheng, Melanie Humphry, Janet J. Maguire, Martin R. Bennett, Murray C.H. Clarke

Immunity. 2013 Feb 21; 38(2): 285–295. doi: 10.1016/j.immuni.2013.01.008

PMCID:: PMC3659285

Abstract Article

Select item 349760018.

Cellular Adaptation to Anthrax Lethal Toxin-Induced Mitochondrial Cholesterol Enrichment, Hyperpolarization, and Reactive Oxygen Species Generation through Downregulating MLN64 in Macrophages

Soon-Duck Ha, Sangwook Park, Chae Young Han, Marilyn L. Nguyen, Sung Ouk Kim

Mol Cell Biol. 2012 Dec; 32(23): 4846–4860. doi: 10.1128/MCB.00494-12

PMCID:: PMC3497600

Abstract Article PDF–3.1M

Select item 327668219.

Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity

Jorge Henao-Mejia, Eran Elinav, Cheng-Cheng Jin, Liming Hao, Wajahat Z. Mehal, Till Strowig, Christoph A. Thaiss, Andrew L. Kau, Stephanie C. Eisenbarth, Michael J. Jurczak, Joao-Paulo Camporez, Gerald I. Shulman, Jeffrey I. Gordon, Hal M. Hoffman, Richard A. Flavell

Nature. Author manuscript; available in PMC 2012 Aug 9.

Published in final edited form as: Nature. 2012 Feb 9; 482(7384): 179–185. Published online 2012 Feb 1. doi: 10.1038/nature10809