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Select item 114673271.

Fat body glycolysis defects inhibit mTOR and promote distant muscle disorganization through TNF-α/egr and ImpL2 signaling in Drosophila larvae

Miriam Rodríguez-Vázquez, Jennifer Falconi, Lisa Heron-Milhavet, Patrice Lassus, Charles Géminard, Alexandre Djiane

EMBO Rep. 2024 Oct; 25(10): 4410–4432. Published online 2024 Sep 9. doi: 10.1038/s44319-024-00241-3

PMCID:: PMC11467327

Abstract Article PDF–6.2M

Select item 113650822.

Systemic coagulopathy promotes host lethality in a new Drosophila tumor model

Tsai-Ching Hsi, Katy L Ong, Jorian J Sepers, Jung Kim, David Bilder

Curr Biol. Author manuscript; available in PMC 2024 Aug 31.

Published in final edited form as: Curr Biol. 2023 Jul 24; 33(14): 3002–3010.e6. Published online 2023 Jun 23. doi: 10.1016/j.cub.2023.05.071

PMCID:: PMC11365082

Abstract Article PDF–1.6M

Select item 113640963.

Context-dependent impact of the dietary non-essential amino acid tyrosine on Drosophila physiology and longevity

Hina Kosakamoto, Chisako Sakuma, Rina Okada, Masayuki Miura, Fumiaki Obata

Sci Adv. 2024 Aug 30; 10(35): eadn7167. Published online 2024 Aug 30. doi: 10.1126/sciadv.adn7167

PMCID:: PMC11364096

Abstract Article PDF–972K

Select item 113640474.

A comprehensive review of animal models for cancer cachexia: Implications for translational research

Li Li, Junaid Wazir, Zhiqiang Huang, Yong Wang, Hongwei Wang

Genes Dis. 2024 Nov; 11(6): 101080. Published online 2023 Sep 13. doi: 10.1016/j.gendis.2023.101080

PMCID:: PMC11364047

Abstract Article PDF–1.1M

Select item 113422505.

Soma-germline communication drives sex maintenance in the Drosophila testis

Rui Zhang, Peiyu Shi, Shuyang Xu, Zhe Ming, Zicong Liu, Yuanyuan He, Junbiao Dai, Erika Matunis, Jin Xu, Qing Ma

Natl Sci Rev. 2024 Aug; 11(8): nwae215. Published online 2024 Jun 22. doi: 10.1093/nsr/nwae215

PMCID:: PMC11342250

Abstract Article PDF–6.6M

Select item 111134716.

Body size regulation and insulin-like growth factor signaling

Seogang Hyun

Cell Mol Life Sci. 2013 Jul; 70(13): 2351–2365. Published online 2013 Mar 19. doi: 10.1007/s00018-013-1313-5

PMCID:: PMC11113471

Abstract Article PDF–682K

Select item 110149927.

Mitochondrial fusion and altered beta-oxidation drive muscle wasting in a Drosophila cachexia model

Callum Dark, Nashia Ali, Sofya Golenkina, Vaibhav Dhyani, Ronnie Blazev, Benjamin L Parker, Kate T Murphy, Gordon S Lynch, Tarosi Senapati, S Sean Millard, Sarah M Judge, Andrew R Judge, Lopamudra Giri, Sarah M Russell, Louise Y Cheng

EMBO Rep. 2024 Apr; 25(4): 1835–1858. Published online 2024 Mar 1. doi: 10.1038/s44319-024-00102-z

PMCID:: PMC11014992

Abstract Article PDF–6.2M

Select item 109904848.

Expanding the Drosophila toolkit for dual control of gene expression

Jonathan Zirin, Barbara Jusiak, Raphael Lopes, Benjamin Ewen-Campen, Justin A Bosch, Alexandria Risbeck, Corey Forman, Christians Villalta, Yanhui Hu, Norbert Perrimon

eLife. 2024; 12: RP94073. Published online 2024 Apr 3. doi: 10.7554/eLife.94073

PMCID:: PMC10990484

Abstract Article PDF–6.0M

Select item 109861329.

JAK/STAT mediated insulin resistance in muscles is essential for effective immune response

Ellen McMullen, Lukas Strych, Lenka Chodakova, Amber Krebs, Tomas Dolezal

Cell Commun Signal. 2024; 22: 203. Published online 2024 Apr 2. doi: 10.1186/s12964-024-01575-0

PMCID:: PMC10986132

Abstract Article PDF–2.8M

Select item 1091779710.

A single-cell atlas of Drosophila trachea reveals glycosylation-mediated Notch signaling in cell fate specification

Yue Li, Tianfeng Lu, Pengzhen Dong, Jian Chen, Qiang Zhao, Yuying Wang, Tianheng Xiao, Honggang Wu, Quanyi Zhao, Hai Huang

Nat Commun. 2024; 15: 2019. Published online 2024 Mar 6. doi: 10.1038/s41467-024-46455-w

PMCID:: PMC10917797

Abstract Article PDF–5.3M

Select item 1090770011.

Baf-mediated transcriptional regulation of teashirt is essential for the development of neural progenitor cell lineages

Byung Su Ko, Myeong Hoon Han, Min Jee Kwon, Dong Gon Cha, Yuri Ji, Eun Seo Park, Min Jae Jeon, Somi Kim, Kyeongho Lee, Yoon Ha Choi, Jusung Lee, Monica Torras-Llort, Ki-Jun Yoon, Hyosang Lee, Jong Kyoung Kim, Sung Bae Lee

Exp Mol Med. 2024 Feb; 56(2): 422–440. Published online 2024 Feb 19. doi: 10.1038/s12276-024-01169-3

PMCID:: PMC10907700

Abstract Article PDF–7.5M

Select item 1087246312.

The roles of the native cell differentiation program aberrantly recapitulated in Drosophila intestinal tumors

Inez Keiko Arlyne Pranoto, Jiae Lee, Young V. Kwon

Cell Rep. Author manuscript; available in PMC 2024 Feb 16.

Published in final edited form as: Cell Rep. 2023 Oct 31; 42(10): 113245. Published online 2023 Oct 12. doi: 10.1016/j.celrep.2023.113245

PMCID:: PMC10872463

Abstract Article PDF–2.6M

Select item 1085680913.

Betulinic Acid Increases the Lifespan of Drosophila melanogaster via Sir2 and FoxO Activation

Hye-Yeon Lee, Kyung-Jin Min

Nutrients. 2024 Feb; 16(3): 441. Published online 2024 Feb 1. doi: 10.3390/nu16030441

PMCID:: PMC10856809

Abstract Article PDF–2.3M

Select item 1077735114.

Magnetic Yeast Glucan Particles for Antibody-Free Separation of Viable Macrophages from Drosophila melanogaster

Gabriela Krejčová, Ivan Saloň, Vojtěch Klimša, Pavel Ulbrich, Ayse Beyza Aysan, Adam Bajgar, František Štěpánek

ACS Biomater Sci Eng. 2024 Jan 8; 10(1): 355–364. Published online 2023 Dec 4. doi: 10.1021/acsbiomaterials.3c01199

PMCID:: PMC10777351

Abstract Article PDF–7.3M

Select item 1070279715.

Convergent insulin and TGF‐β signalling drives cancer cachexia by promoting aberrant fat body ECM accumulation in a Drosophila tumour model

Daniel Bakopoulos, Sofya Golenkina, Callum Dark, Elizabeth L Christie, Besaiz J Sánchez‐Sánchez, Brian M Stramer, Louise Y Cheng

EMBO Rep. 2023 Dec; 24(12): e57695. Published online 2023 Nov 28. doi: 10.15252/embr.202357695

PMCID:: PMC10702797

Abstract Article PDF–14M

Select item 1069047116.

Macrophage‐derived insulin antagonist ImpL2 induces lipoprotein mobilization upon bacterial infection

Gabriela Krejčová, Cecilia Morgantini, Helena Zemanová, Volker M Lauschke, Julie Kovářová, Jiří Kubásek, Pavla Nedbalová, Nick Kamps‐Hughes, Martin Moos, Myriam Aouadi, Tomáš Doležal, Adam Bajgar

EMBO J. 2023 Dec; 42(23): e114086. Published online 2023 Oct 9. doi: 10.15252/embj.2023114086

PMCID:: PMC10690471

Abstract Article PDF–5.5M

Select item 1067006417.

Sustained Nrf2 Overexpression-Induced Metabolic Deregulation Can Be Attenuated by Modulating Insulin/Insulin-like Growth Factor Signaling

Sentiljana Gumeni, Maria Lamprou, Zoi Evangelakou, Maria S. Manola, Ioannis P. Trougakos

Cells. 2023 Nov; 12(22): 2650. Published online 2023 Nov 18. doi: 10.3390/cells12222650

PMCID:: PMC10670064

Abstract Article PDF–2.1M

Select item 1065376618.

Role of gut commensal bacteria in juvenile developmental growth of the host: insights from Drosophila studies

Hyun Myoung Yun, Seogang Hyun

Anim Cells Syst (Seoul) 2023; 27(1): 329–339. Published online 2023 Nov 15. doi: 10.1080/19768354.2023.2282726

PMCID:: PMC10653766

Abstract Article PDF–1.1M

Select item 1059016119.

The reproductive status determines tolerance and resistance to Mycobacterium marinum in Drosophila melanogaster

Marta Arch, Maria Vidal, Esther Fuentes, Anmaw Shite Abat, Pere-Joan Cardona

Evol Med Public Health. 2023; 11(1): 332–347. Published online 2023 Sep 6. doi: 10.1093/emph/eoad029

PMCID:: PMC10590161

Abstract Article PDF–907K

Select item 1042769620.

REPTOR and CREBRF encode key regulators of muscle energy metabolism

Pedro Saavedra, Phillip A. Dumesic, Yanhui Hu, Elizabeth Filine, Patrick Jouandin, Richard Binari, Sarah E. Wilensky, Jonathan Rodiger, Haiyun Wang, Weihang Chen, Ying Liu, Bruce M. Spiegelman, Norbert Perrimon

Nat Commun. 2023; 14: 4943. Published online 2023 Aug 15. doi: 10.1038/s41467-023-40595-1