PMC Links for GEO Profiles (Select 36211270) - PMC

Inge Kinnart, Liselot Manders, Thibaut Heyninck, Dorien Imberechts, Roman Praschberger, Nils Schoovaerts, Catherine Verfaillie, Patrik Verstreken, Wim Vandenberghe

NPJ Parkinsons Dis. 2024; 10: 80. Published online 2024 Apr 9. doi: 10.1038/s41531-024-00696-0

PMCID:: PMC11004019

Abstract Article PDF–6.7M

Select item 110015864.

A neuron–glia lipid metabolic cycle couples daily sleep to mitochondrial homeostasis

Paula R. Haynes, Elana S. Pyfrom, Yongjun Li, Carly Stein, Vishnu Anand Cuddapah, Jack A. Jacobs, Zhifeng Yue, Amita Sehgal

Nat Neurosci. 2024; 27(4): 666–678. Published online 2024 Feb 15. doi: 10.1038/s41593-023-01568-1

PMCID:: PMC11001586

Abstract Article PDF–5.6M

Select item 108501615.

Activation of Ca²⁺ phosphatase Calcineurin regulates Parkin translocation to mitochondria and mitophagy in flies

Elena Marchesan, Alice Nardin, Sofia Mauri, Greta Bernardo, Vivek Chander, Simone Di Paola, Monica Chinellato, Sophia von Stockum, Joy Chakraborty, Stephanie Herkenne, Valentina Basso, Emilie Schrepfer, Oriano Marin, Laura Cendron, Diego L. Medina, Luca Scorrano, Elena Ziviani

Cell Death Differ. 2024 Feb; 31(2): 217–238. Published online 2024 Jan 18. doi: 10.1038/s41418-023-01251-9

PMCID:: PMC10850161

Abstract Article PDF–19M

Select item 108448626.

mtDNA extramitochondrial replication mediates mitochondrial defect effects

Zhaoliang Shan, Shengnan Li, Yuxue Gao, Chunhua Jian, Xiuxiu Ti, Hui Zuo, Ying Wang, Guochun Zhao, Yan Wang, Qing Zhang

iScience. 2024 Feb 16; 27(2): 108970. Published online 2024 Jan 19. doi: 10.1016/j.isci.2024.108970

PMCID:: PMC10844862

Abstract Article PDF–8.0M

Select item 108118607.

Mitochondrial CISD1/Cisd accumulation blocks mitophagy and genetic or pharmacological inhibition rescues neurodegenerative phenotypes in Pink1/parkin models

Aitor Martinez, Alvaro Sanchez-Martinez, Jake T. Pickering, Madeleine J. Twyning, Ana Terriente-Felix, Po-Lin Chen, Chun-Hong Chen, Alexander J. Whitworth

Mol Neurodegener. 2024; 19: 12. Published online 2024 Jan 25. doi: 10.1186/s13024-024-00701-3

PMCID:: PMC10811860

Abstract Article PDF–13M

Select item 107943138.

Analysis of α-syn and parkin interaction in mediating neuronal death in Drosophila model of Parkinson's disease

Sonia Narwal, Amit Singh, Meghana Tare

Front Cell Neurosci. 2023; 17: 1295805. Published online 2024 Jan 4. doi: 10.3389/fncel.2023.1295805

PMCID:: PMC10794313

Abstract Article PDF–2.7M

Select item 106450799.

Structure and molecular basis of spermatid elongation in the Drosophila testis

Qiuru Huang, Xia Chen, Hao Yu, Li Ji, Yi Shi, Xinmeng Cheng, Hao Chen, Jun Yu

Open Biol. 2023 Nov; 13(11): 230136. Published online November 8, 2023. doi: 10.1098/rsob.230136

PMCID:: PMC10645079

Abstract Article PDF–1.0M

Select item 1045734210.

PINK1 and Parkin regulate IP₃R-mediated ER calcium release

Su Jin Ham, Heesuk Yoo, Daihn Woo, Da Hyun Lee, Kyu-Sang Park, Jongkyeong Chung

Nat Commun. 2023; 14: 5202. Published online 2023 Aug 25. doi: 10.1038/s41467-023-40929-z

PMCID:: PMC10457342

Abstract Article PDF–3.1M

Select item 1045058011.

Milton assembles large mitochondrial clusters, mitoballs, to sustain spermatogenesis

Andy Y. Z. Li, Ying Di, Sumaera Rathore, Ason C.-Y. Chiang, Jan Jezek, Hansong Ma

Proc Natl Acad Sci U S A. 2023 Aug 22; 120(34): e2306073120. Published online 2023 Aug 14. doi: 10.1073/pnas.2306073120

PMCID:: PMC10450580

Abstract Article PDF–8.2M

Select item 1044320312.

A phosphate-sensing organelle regulates phosphate and tissue homeostasis

Chiwei Xu, Jun Xu, Hong-Wen Tang, Maria Ericsson, Jui-Hsia Weng, Jonathan DiRusso, Yanhui Hu, Wenzhe Ma, John M. Asara, Norbert Perrimon

Nature. Author manuscript; available in PMC 2023 Nov 3.

Published in final edited form as: Nature. 2023 May; 617(7962): 798–806. Published online 2023 May 3. doi: 10.1038/s41586-023-06039-y

PMCID:: PMC10443203

Abstract Article PDF–7.2M

Select item 1042702013.

FBXO7/ntc and USP30 antagonistically set the ubiquitination threshold for basal mitophagy and provide a target for Pink1 phosphorylation in vivo

Alvaro Sanchez-Martinez, Aitor Martinez, Alexander J. Whitworth

PLoS Biol. 2023 Aug; 21(8): e3002244. Published online 2023 Aug 3. doi: 10.1371/journal.pbio.3002244

PMCID:: PMC10427020

Abstract Article PDF–3.6M

Select item 1036829514.

Loss of STING in parkin mutant flies suppresses muscle defects and mitochondria damage

Andrew T. Moehlman, Gil Kanfer, Richard J. Youle

PLoS Genet. 2023 Jul; 19(7): e1010828. Published online 2023 Jul 13. doi: 10.1371/journal.pgen.1010828

PMCID:: PMC10368295

Abstract Article PDF–3.8M

Select item 1028340915.

PRKN/parkin-mediated mitophagy is induced by the probiotics Saccharomyces boulardii and Lactococcus lactis

Peter John Hawrysh, Jinghua Gao, Stephanie Tan, Amy Oh, Justin Nodwell, Thomas A. Tompkins, G. Angus McQuibban

Autophagy. 2023; 19(7): 2094–2110. Published online 2023 Feb 5. doi: 10.1080/15548627.2023.2172873

PMCID:: PMC10283409

Abstract Article PDF–4.0M

Select item 1027290116.

Humanization for neurological disease modeling: A roadmap to increase the potential of Drosophila model systems

Vladimir L. Katanaev

Animal Model Exp Med. 2023 Jun; 6(3): 230–236. Published online 2023 May 8. doi: 10.1002/ame2.12322

PMCID:: PMC10272901

Abstract Article PDF–877K

Select item 1023277517.

Drosophila melanogaster as a model to study autophagy in neurodegenerative diseases induced by proteinopathies

Stefania Santarelli, Chiara Londero, Alessia Soldano, Carlotta Candelaresi, Leonardo Todeschini, Luisa Vernizzi, Paola Bellosta

Front Neurosci. 2023; 17: 1082047. Published online 2023 May 18. doi: 10.3389/fnins.2023.1082047

PMCID:: PMC10232775

Abstract Article PDF–2.4M

Select item 1016254518.

Bendless is essential for PINK1-Park mediated Mitofusin degradation under mitochondrial stress caused by loss of LRPPRC

Rajit Narayanan Cheramangalam, Tarana Anand, Priyanka Pandey, Deepa Balasubramanian, Reshmi Varghese, Neha Singhal, Sonal Nagarkar Jaiswal, Manish Jaiswal

PLoS Genet. 2023 Apr; 19(4): e1010493. Published online 2023 Apr 25. doi: 10.1371/journal.pgen.1010493

PMCID:: PMC10162545

Abstract Article PDF–7.7M

Select item 1013664519.

USP8 Down-Regulation Promotes Parkin-Independent Mitophagy in the Drosophila Brain and in Human Neurons

Sofia Mauri, Greta Bernardo, Aitor Martinez, Mariavittoria Favaro, Marta Trevisan, Gael Cobraiville, Marianne Fillet, Federico Caicci, Alexander J. Whitworth, Elena Ziviani

Cells. 2023 Apr; 12(8): 1143. Published online 2023 Apr 13. doi: 10.3390/cells12081143

PMCID:: PMC10136645

Abstract Article PDF–4.7M

Select item 1011516720.

PTPA variants and impaired PP2A activity in early-onset parkinsonism with intellectual disability

Christina Fevga, Christelle Tesson, Ana Carreras Mascaro, Thomas Courtin, Riaan van Coller, Salma Sakka, Federico Ferraro, Nouha Farhat, Soraya Bardien, Mariem Damak, Jonathan Carr, Mélanie Ferrien, Valerie Boumeester, Jasmijn Hundscheid, Nicola Grillenzoni, Irini A Kessissoglou, Demy J S Kuipers, Marialuisa Quadri, French and Mediterranean Parkinson disease Genetics Study Group , International Parkinsonism Genetics Network , Jean-Christophe Corvol, Chokri Mhiri, Bassem A Hassan, Guido J Breedveld, Suzanne Lesage, Wim Mandemakers, Alexis Brice, Vincenzo Bonifati

Brain. 2023 Apr; 146(4): 1496–1510. Published online 2022 Sep 8. doi: 10.1093/brain/awac326

PMCID:: PMC10115167

Abstract Article PDF–1.7M

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