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Select item 101737181.

Folic acid deficiency exacerbates the inflammatory response of astrocytes after ischemia‐reperfusion by enhancing the interaction between IL‐6 and JAK‐1/pSTAT3

Man Cheng, Xiaoshan Liang, Linran Shi, Qiang Zhang, Liwen Zhang, Zhongying Gong, Suhui Luo, Xuan Wang, Xumei Zhang

CNS Neurosci Ther. 2023 Jun; 29(6): 1537–1546. Published online 2023 Feb 16. doi: 10.1111/cns.14116

PMCID:: PMC10173718

Abstract Article PDF–15M

Select item 79831562.

IL-7-induced phosphorylation of the adaptor Crk-like and other targets

Francesca B. Aiello, Tad Guszczynski, Wenqing Li, Julie A. Hixon, Qiong Jiang, Deborah L. Hodge, Tania Massignan, Chiara Di Lisio, Anand Merchant, Antonio D. Procopio, Valentina Bonetto, Scott K. Durum

Cell Signal. Author manuscript; available in PMC 2021 Mar 22.

Published in final edited form as: Cell Signal. 2018 Jul; 47: 131–141. Published online 2018 Mar 24. doi: 10.1016/j.cellsig.2018.03.008

PMCID:: PMC7983156

Abstract Article PDF–1.7M

Select item 69881313.

Generation of Janus kinase 1 (JAK1) conditional knockout mice

Kazuhito Sakamoto, Barbara L. Wehde, Patrick D. Rädler, Aleata A. Triplett, Kay-Uwe Wagner

Genesis. Author manuscript; available in PMC 2020 Jan 29.

Published in final edited form as: Genesis. 2016 Nov; 54(11): 582–588. Published online 2016 Oct 19. doi: 10.1002/dvg.22982

PMCID:: PMC6988131

Abstract Article PDF–722K

Select item 63900714.

Curculigoside exerts significant anti-arthritic effects in vivo and in vitro via regulation of the JAK/STAT/NF-κB signaling pathway

Shirui Tan, Jian Xu, Aiyun Lai, Ruomei Cui, Ru Bai, Shu Li, Wei Liang, Guofang Zhang, Shaoquan Jiang, Shuang Liu, Mai Zheng, Wei Wang

Mol Med Rep. 2019 Mar; 19(3): 2057–2064. Published online 2019 Jan 14. doi: 10.3892/mmr.2019.9854

PMCID:: PMC6390071

Abstract Article PDF–1.4M

Select item 58020295.

Combination of gemcitabine and erlotinib inhibits recurrent pancreatic cancer growth in mice via the JAK-STAT pathway

Liwen Chen, Ding'An Zhou, Zhehao Liu, Xinhao Huang, Qianfan Liu, Yiping Kang, Zili Chen, Yuntao Guo, Haitao Zhu, Chengyi Sun

Oncol Rep. 2018 Mar; 39(3): 1081–1089. Published online 2018 Jan 8. doi: 10.3892/or.2018.6198

PMCID:: PMC5802029

Abstract Article PDF–940K

Select item 56796126.

Loss of function JAK1 mutations occur at high frequency in cancers with microsatellite instability and are suggestive of immune evasion

Lee A. Albacker, Jeremy Wu, Peter Smith, Markus Warmuth, Philip J. Stephens, Ping Zhu, Lihua Yu, Juliann Chmielecki

PLoS One. 2017; 12(11): e0176181. Published online 2017 Nov 9. doi: 10.1371/journal.pone.0176181

PMCID:: PMC5679612

Abstract Article PDF–4.8M

Select item 56204867.

Activation of Janus kinase 1 confers poor prognosis in patients with non-small cell lung cancer

Dan Liu, Yi Huang, Li Zhang, Dong-Ni Liang, Li Li

Oncol Lett. 2017 Oct; 14(4): 3959–3966. Published online 2017 Aug 1. doi: 10.3892/ol.2017.6690

PMCID:: PMC5620486

Abstract Article PDF–1.1M

Select item 54428738.

Multilevel genomics of colorectal cancers with microsatellite instability—clinical impact of JAK1 mutations and consensus molecular subtype 1

Anita Sveen, Bjarne Johannessen, Torstein Tengs, Stine A. Danielsen, Ina A. Eilertsen, Guro E. Lind, Kaja C. G. Berg, Edward Leithe, Leonardo A. Meza-Zepeda, Enric Domingo, Ola Myklebost, David Kerr, Ian Tomlinson, Arild Nesbakken, Rolf I. Skotheim, Ragnhild A. Lothe

Genome Med. 2017; 9: 46. Published online 2017 May 24. doi: 10.1186/s13073-017-0434-0

PMCID:: PMC5442873

Abstract Article PDF–971K

Select item 50537139.

Associations of potentially functional variants in IL-6, JAKs and STAT3 with gastric cancer risk in an eastern Chinese population

Fei Zhou, Lei Cheng, Li-Xin Qiu, Meng-Yun Wang, Jin Li, Meng-Hong Sun, Ya-Jun Yang, Jiu-Cun Wang, Li Jin, Ya-Nong Wang, Qing-Yi Wei

Oncotarget. 2016 May 10; 7(19): 28112–28123. Published online 2016 Mar 30. doi: 10.18632/oncotarget.8492

PMCID:: PMC5053713

Abstract Article PDF–2.0M

Select item 486869810.

Activating JAK1 mutation may predict the sensitivity of JAK-STAT inhibition in hepatocellular carcinoma

Shuqun Yang, Chonglin Luo, Qingyang Gu, Qiang Xu, Guan Wang, Hongye Sun, Ziliang Qian, Yexiong Tan, Yuxin Qin, Yuhong Shen, Xiaowei Xu, Shu-Hui Chen, Chi-Chung Chan, Hongyang Wang, Mao Mao, Douglas D. Fang

Oncotarget. 2016 Feb 2; 7(5): 5461–5469. Published online 2015 Dec 19. doi: 10.18632/oncotarget.6684

PMCID:: PMC4868698

Abstract Article PDF–4.7M

Select item 432196111.

Targeting JAK1/STAT3 signaling suppresses tumor progression and metastasis in a peritoneal model of human ovarian cancer

Wei Wen, Wei Liang, Jun Wu, Claudia M. Kowolik, Ralf Buettner, Anna Scuto, Meng-Yin Hsieh, Hao Hong, Christine E. Brown, Stephen J. Forman, David Horne, Robert Morgan, Mark Wakabayashi, Thanh H. Dellinger, Ernest S. Han, John H. Yim, Richard Jove

Mol Cancer Ther. Author manuscript; available in PMC 2015 Dec 1.

Published in final edited form as: Mol Cancer Ther. 2014 Dec; 13(12): 3037–3048. Published online 2014 Oct 15. doi: 10.1158/1535-7163.MCT-14-0077

PMCID:: PMC4321961

Abstract Article PDF–745K

Select item 411401912.

Unanchored K48-linked poly-ubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKε kinase mediated antiviral response

Ricardo Rajsbaum, Gijs A. Versteeg, Sonja Schmid, Ana M. Maestre, Alan Belicha-Villanueva, Carles Martínez-Romero, Jenish R. Patel, Juliet Morrison, Giuseppe Pisanelli, Lisa Miorin, Maudry Laurent-Rolle, Hong M. Moulton, David A. Stein, Ana Fernandez-Sesma, Benjamin R. tenOever, Adolfo García-Sastre

Immunity. Author manuscript; available in PMC 2015 Jun 19.

Published in final edited form as: Immunity. 2014 Jun 19; 40(6): 880–895. Published online 2014 May 29. doi: 10.1016/j.immuni.2014.04.018

PMCID:: PMC4114019

Abstract Article PDF–2.7M

Select item 401602713.

Diabetes impairs an interleukin-1β-dependent pathway that enhances neurite outgrowth through JAK/STAT3 modulation of mitochondrial bioenergetics in adult sensory neurons

Ali Saleh, Subir K Roy Chowdhury, Darrell R Smith, Savitha Balakrishnan, Lori Tessler, Emily Schartner, Andre Bilodeau, Randy Van Der Ploeg, Paul Fernyhough

Mol Brain. 2013; 6: 45. Published online 2013 Oct 24. doi: 10.1186/1756-6606-6-45

PMCID:: PMC4016027

Abstract Article PDF–1.9M

Select item 375971914.

Whole-genome sequencing identifies recurrent mutations in hepatocellular carcinoma

Zhengyan Kan, Hancheng Zheng, Xiao Liu, Shuyu Li, Thomas D. Barber, Zhuolin Gong, Huan Gao, Ke Hao, Melinda D. Willard, Jiangchun Xu, Robert Hauptschein, Paul A. Rejto, Julio Fernandez, Guan Wang, Qinghui Zhang, Bo Wang, Ronghua Chen, Jian Wang, Nikki P. Lee, Wei Zhou, Zhao Lin, Zhiyu Peng, Kang Yi, Shengpei Chen, Lin Li, Xiaomei Fan, Jie Yang, Rui Ye, Jia Ju, Kai Wang, Heather Estrella, Shibing Deng, Ping Wei, Ming Qiu, Isabella H. Wulur, Jiangang Liu, Mariam E. Ehsani, Chunsheng Zhang, Andrey Loboda, Wing Kin Sung, Amit Aggarwal, Ronnie T. Poon, Sheung Tat Fan, Jun Wang, James Hardwick, Christoph Reinhard, Hongyue Dai, Yingrui Li, John M. Luk, Mao Mao

Genome Res. 2013 Sep; 23(9): 1422–1433. doi: 10.1101/gr.154492.113

PMCID:: PMC3759719

Abstract Article PDF–1.6M

Select item 373206815.

SOCS1 gene transfer accelerates the transition to heart failure through the inhibition of the gp130/JAK/STAT pathway

Antonio Cittadini, Maria Gaia Monti, Guido Iaccarino, Maria Carmina Castiello, Alfonso Baldi, Eduardo Bossone, Salvatore Longobardi, Alberto Maria Marra, Valentina Petrillo, Lavinia Saldamarco, Matthew John During, Luigi Saccà, Gianluigi Condorelli

Cardiovasc Res. 2012 Dec 1; 96(3): 381–390. Published online 2012 Aug 8. doi: 10.1093/cvr/cvs261

PMCID:: PMC3732068

Abstract Article PDF–585K

Select item 349604016.

Depletion of Cellular Glutathione Modulates LIF-Induced JAK1-STAT3 Signaling in Cardiac Myocytes

Mazen Kurdi, Vidhya Sivakumaran, Roy J. Duhé, Miguel A. Aon, Nazareno Paolocci, George W. Booz

Int J Biochem Cell Biol. Author manuscript; available in PMC 2013 Dec 1.

Published in final edited form as: Int J Biochem Cell Biol. 2012 Dec; 44(12): 2106–2115. Published online 2012 Aug 22. doi: 10.1016/j.biocel.2012.08.016