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Items: 1 to 20 of 24

1.
A phase II study of ENMD-2076 in advanced soft tissue sarcoma (STS)
Zachary Veitch, Alona Zer, Herbert Loong, Samer Salah, Maryam Masood, Abha Gupta, Penelope A. Bradbury, David Hogg, Andrew Wong, Rita Kandel, George S. Charames, Albiruni R. Abdul Razak
Sci Rep. 2019; 9: 7390. Published online 2019 May 14. doi: 10.1038/s41598-019-43222-6
PMCID:
PMC6517396
AbstractArticlePDF–1.3M
2.
Aβ inhibits SREBP-2 activation through Akt inhibition
Amany Mohamed, Anissa Viveiros, Kathleen Williams, Elena Posse de Chaves
J Lipid Res. 2018 Jan; 59(1): 1–13. Published online 2017 Nov 9. doi: 10.1194/jlr.M076703
PMCID:
PMC5748492
AbstractArticlePDF–1.2M
3.
Sterol Regulatory Element-Binding Proteins Are Regulators of the NIS Gene in Thyroid Cells
Robert Ringseis, Christine Rauer, Susanne Rothe, Denise K. Gessner, Lisa-Marie Schütz, Sebastian Luci, Gaiping Wen, Klaus Eder
Mol Endocrinol. May 1, 2013; 27(5): 781–800. Published online 2013 Mar 29. doi: 10.1210/me.2012-1269
PMCID:
PMC5416757
AbstractArticle
4.
Expression of Sterol Regulatory Element-Binding Proteins in epicardial adipose tissue in patients with coronary artery disease and diabetes mellitus: preliminary study
Luis M. Pérez-Belmonte, Inmaculada Moreno-Santos, Fernando Cabrera-Bueno, Gemma Sánchez-Espín, Daniel Castellano, Miguel Such, María G Crespo-Leiro, Fernando Carrasco-Chinchilla, Luis Alonso-Pulpón, Miguel López-Garrido, Amalio Ruiz-Salas, Víctor M. Becerra-Muñoz, Juan J. Gómez-Doblas, Eduardo de Teresa-Galván, Manuel Jiménez-Navarro
Int J Med Sci. 2017; 14(3): 268–274. Published online 2017 Feb 23. doi: 10.7150/ijms.17821
PMCID:
PMC5370289
AbstractArticlePDF–325K
5.
Nutrient deprivation induces α-synuclein aggregation through endoplasmic reticulum stress response and SREBP2 pathway
Peizhou Jiang, Ming Gan, Wen-Lang Lin, Shu-Hui C. Yen
Front Aging Neurosci. 2014; 6: 268. Published online 2014 Oct 8. doi: 10.3389/fnagi.2014.00268
PMCID:
PMC4189422
AbstractArticlePDF–3.7M
6.
Genome-wide RNAi screen identifies the Parkinson disease GWAS risk locus SREBF1 as a regulator of mitophagy
Rachael M. Ivatt, Alvaro Sanchez-Martinez, Vinay K. Godena, Stephen Brown, Elena Ziviani, Alexander J. Whitworth
Proc Natl Acad Sci U S A. 2014 Jun 10; 111(23): 8494–8499. Published online 2014 May 27. doi: 10.1073/pnas.1321207111
PMCID:
PMC4060696
AbstractArticlePDF–1.5M
7.
Enhanced circulating PCSK9 concentration by berberine through SREBP-2 pathway in high fat diet-fed rats
Yan-Jun Jia, Rui-Xa Xu, Jing Sun, Yue Tang, Jian-Jun Li
J Transl Med. 2014; 12: 103. Published online 2014 Apr 23. doi: 10.1186/1479-5876-12-103
PMCID:
PMC4000533
AbstractArticlePDF–657K
8.
Sterol Regulatory Element-Binding Proteins Are Regulators of the Rat Thyroid Peroxidase Gene in Thyroid Cells
Christine Rauer, Robert Ringseis, Susanne Rothe, Gaiping Wen, Klaus Eder
PLoS One. 2014; 9(3): e91265. Published online 2014 Mar 13. doi: 10.1371/journal.pone.0091265
PMCID:
PMC3953333
AbstractArticlePDF–5.8M
9.
MicroRNA-33 and the SREBP Host Genes Cooperate to Control Cholesterol Homeostasis
S. Hani Najafi-Shoushtari, Fjoralba Kristo, Yingxia Li, Toshi Shioda, David E. Cohen, Robert E. Gerszten, Anders M. Näär
Science. Author manuscript; available in PMC 2013 Nov 26.
Published in final edited form as: Science. 2010 Jun 18; 328(5985): 10.1126/science.1189123. Published online 2010 May 13. doi: 10.1126/science.1189123
PMCID:
PMC3840500
AbstractArticlePDF–1.0M
10.
Xanthohumol ameliorates atherosclerotic plaque formation, hypercholesterolemia, and hepatic steatosis in ApoE-deficient mice
Prakash Doddapattar, Branislav Radović, Jay V. Patankar, Sascha Obrowsky, Katharina Jandl, Christoph Nusshold, Dagmar Kolb, Nemanja Vujić, Lalit Doshi, Prakash G. Chandak, Madeleine Goeritzer, Helmut Ahammer, Gerald Hoefler, Wolfgang Sattler, Dagmar Kratky
Mol Nutr Food Res. Author manuscript; available in PMC 2013 Dec 1.
Published in final edited form as: Mol Nutr Food Res. 2013 Oct; 57(10): 1718–1728. Published online 2013 May 3. doi: 10.1002/mnfr.201200794
PMCID:
PMC3771820
AbstractArticlePDF–2.3M
11.
An SREBP Responsive micro-RNA Operon Contributes to a Regulatory Loop for Intracellular Lipid Homeostasis
Tae-Il Jeon, Ryan M. Esquejo, Manuel Roqueta-Rivera, Peter E. Phelan, Young-Ah Moon, Subramaniam S. Govindarajan, Christine C. Esau, Timothy F. Osborne
Cell Metab. Author manuscript; available in PMC 2014 Jul 2.
Published in final edited form as: Cell Metab. 2013 Jul 2; 18(1): 51–61. doi: 10.1016/j.cmet.2013.06.010
PMCID:
PMC3740797
AbstractArticlePDF–1.3M
12.
Mutant p53: one name, many proteins
William A. Freed-Pastor, Carol Prives
Genes Dev. 2012 Jun 15; 26(12): 1268–1286. doi: 10.1101/gad.190678.112
PMCID:
PMC3387655
AbstractArticlePDF–412K
13.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
14.
Curcumin Inhibits srebp-2 Expression in Activated Hepatic Stellate Cells in Vitro by Reducing the Activity of Specificity Protein-1
Qiaohua Kang, Anping Chen
Endocrinology. 2009 Dec; 150(12): 5384–5394. Published online 2009 Oct 6. doi: 10.1210/en.2009-0517
PMCID:
PMC2795713
AbstractArticle
15.
Evolutionary conservation and adaptation in the mechanism that regulates SREBP action: what a long, strange tRIP it's been
Timothy F. Osborne, Peter J. Espenshade
Genes Dev. 2009 Nov 15; 23(22): 2578–2591. doi: 10.1101/gad.1854309
PMCID:
PMC2779761
AbstractArticlePDF–347K
16.
In Vivo Identification of Promoter Elements and Transcription Factors Mediating Activation of Hepatic HMG CoA Reductase by T3
Lindsey R. Boone, Melissa I. Niesen, Mark Jaroszeski, Gene C. Ness
Biochem Biophys Res Commun. Author manuscript; available in PMC 2010 Jul 31.
Published in final edited form as: Biochem Biophys Res Commun. 2009 Jul 31; 385(3): 466–471. Published online 2009 May 24. doi: 10.1016/j.bbrc.2009.05.093
PMCID:
PMC2748396
AbstractArticlePDF–979K
17.
SRF and myocardin regulate LRP-mediated amyloid-ß clearance in brain vascular cells
Robert D. Bell, Rashid Deane, Nienwen Chow, Xiaochun Long, Abhay Sagare, Itender Singh, Jeffrey W. Streb, Huang Guo, Anna Rubio, William Van Nostrand, Joseph M. Miano, Berislav V. Zlokovic
Nat Cell Biol. Author manuscript; available in PMC 2009 Aug 1.
Published in final edited form as: Nat Cell Biol. 2009 Feb; 11(2): 143–153. Published online 2008 Dec 21. doi: 10.1038/ncb1819
PMCID:
PMC2654279
AbstractArticlePDF–4.9M
18.
Identification of mutations in the gene encoding sterol regulatory element binding protein (SREBP)-2 in hypercholesterolaemic subjects
P Muller, A Miserez
J Med Genet. 2002 Apr; 39(4): 271–275. doi: 10.1136/jmg.39.4.271
PMCID:
PMC1735089
SummaryPDF–148K
19.
Lipid deprivation increases surfactant phosphatidylcholine synthesis via a sterol-sensitive regulatory element within the CTP:phosphocholine cytidylyltransferase promoter.
Rama K Mallampalli, Alan J Ryan, James L Carroll, Timothy F Osborne, Christie P Thomas
Biochem J. 2002 Feb 15; 362(Pt 1): 81–88. doi: 10.1042/0264-6021:3620081
PMCID:
PMC1222362
SummaryPDF–197K
20.
Schoenheimer effect explained – feedback regulation of cholesterol synthesis in mice mediated by Insig proteins
Luke J. Engelking, Guosheng Liang, Robert E. Hammer, Kiyosumi Takaishi, Hiroshi Kuriyama, Bret M. Evers, Wei-Ping Li, Jay D. Horton, Joseph L. Goldstein, Michael S. Brown
J Clin Invest. 2005 Sep 1; 115(9): 2489–2498. Published online 2005 Aug 11. doi: 10.1172/JCI25614
PMCID:
PMC1184040
AbstractArticlePDF–1.2M

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