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Select item 73823701.

Watching helical membrane proteins fold reveals a common N- to C-terminal folding pathway

Hyun-Kyu Choi, Duyoung Min, Hyunook Kang, Min Ju Shon, Sang-Hyun Rah, Hak Chan Kim, Hawoong Jeong, Hee-Jung Choi, James U. Bowie, Tae-Young Yoon

Science. Author manuscript; available in PMC 2020 Nov 29.

Published in final edited form as: Science. 2019 Nov 29; 366(6469): 1150–1156. doi: 10.1126/science.aaw8208

PMCID:: PMC7382370

Article PDF–1.9M

Select item 54426142.

The Rhomboid Protease GlpG Promotes the Persistence of Extraintestinal Pathogenic Escherichia coli within the Gut

Colin W. Russell, Amanda C. Richards, Alexander S. Chang, Matthew A. Mulvey

Infect Immun. 2017 Jun; 85(6): e00866-16. Prepublished online 2017 Apr 3. Published online 2017 May 23. doi: 10.1128/IAI.00866-16

PMCID:: PMC5442614

Article PDF–1.7M

Select item 47765033.

Topological constraints and modular structure in the folding and functional motions of GlpG, an intramembrane protease

Nicholas P. Schafer, Ha H. Truong, Daniel E. Otzen, Kresten Lindorff-Larsen, Peter G. Wolynes

Proc Natl Acad Sci U S A. 2016 Feb 23; 113(8): 2098–2103. Published online 2016 Feb 8. doi: 10.1073/pnas.1524027113

PMCID:: PMC4776503

Article PDF–1.5M

Select item 44917324.

Cooperative folding of a polytopic α-helical membrane protein involves a compact N-terminal nucleus and nonnative loops

Wojciech Paslawski, Ove K. Lillelund, Julie Veje Kristensen, Nicholas P. Schafer, Rosanna P. Baker, Sinisa Urban, Daniel E. Otzen

Proc Natl Acad Sci U S A. 2015 Jun 30; 112(26): 7978–7983. Published online 2015 Jun 8. doi: 10.1073/pnas.1424751112

PMCID:: PMC4491732

Article PDF–1.0M

Select item 43809785.

Influence of hydrophobic mismatch on the catalytic activity of Escherichia coli GlpG rhomboid protease

Alexander C Y Foo, Brandon G R Harvey, Jeff J Metz, Natalie K Goto

Protein Sci. 2015 Apr; 24(4): 464–473. Published online 2014 Oct 11. doi: 10.1002/pro.2585

PMCID:: PMC4380978

Article PDF–416K

Select item 42535286.

Substrate binding and specificity of rhomboid intramembrane protease revealed by substrate–peptide complex structures

Sebastian Zoll, Stancho Stanchev, Jakub Began, Jan Škerle, Martin Lepšík, Lucie Peclinovská, Pavel Majer, Kvido Strisovsky

EMBO J. 2014 Oct 16; 33(20): 2408–2421. Published online 2014 Sep 12. doi: 10.15252/embj.201489367

PMCID:: PMC4253528

Article PDF–4.1M

Select item 41957837.

Allosteric regulation of rhomboid intramembrane proteolysis

Elena Arutyunova, Pankaj Panwar, Pauline M Skiba, Nicola Gale, Michelle W Mak, M Joanne Lemieux

EMBO J. 2014 Sep 1; 33(17): 1869–1881. Published online 2014 Jul 9. doi: 10.15252/embj.201488149

PMCID:: PMC4195783

Article PDF–1.1M

Select item 41238558.

The binary protein-protein interaction landscape of Escherichia coli

Seesandra V. Rajagopala, Patricia Sikorski, Ashwani Kumar, Roberto Mosca, James Vlasblom, Roland Arnold, Jonathan Franca-Koh, Suman B. Pakala, Sadhna Phanse, Arnaud Ceol, Roman Häuser, Gabriella Siszler, Stefan Wuchty, Andrew Emili, Mohan Babu, Patrick Aloy, Rembert Pieper, Peter Uetz

Nat Biotechnol. Author manuscript; available in PMC 2014 Sep 1.

Published in final edited form as: Nat Biotechnol. 2014 Mar; 32(3): 285–290. Published online 2014 Feb 23. doi: 10.1038/nbt.2831

PMCID:: PMC4123855

Article PDF–1.1M

Select item 39173179.

Proteolysis inside the membrane is a rate-governed reaction not driven by substrate affinity

Seth W. Dickey, Rosanna P. Baker, Sangwoo Cho, Siniša Urban

Cell. Author manuscript; available in PMC 2014 Dec 5.

Published in final edited form as: Cell. 2013 Dec 5; 155(6): 1270–1281. doi: 10.1016/j.cell.2013.10.053

PMCID:: PMC3917317

Article PDF–3.0M

Select item 366870410.

Structure and Mechanism of Rhomboid Protease

Ya Ha, Yoshinori Akiyama, Yi Xue

J Biol Chem. 2013 May 31; 288(22): 15430–15436. Published online 2013 Apr 12. doi: 10.1074/jbc.R112.422378

PMCID:: PMC3668704

Article PDF–1.4M

Select item 267994711.

Rhomboid protease dynamics and lipid interactions

Ana-Nicoleta Bondar, Coral del Val, Stephen H. White

Structure. Author manuscript; available in PMC 2010 Mar 11.

Published in final edited form as: Structure. 2009 Mar 11; 17(3): 395–405. doi: 10.1016/j.str.2008.12.017

PMCID:: PMC2679947

Article PDF–2.7M

Select item 267875612.

In vivo analysis reveals substrate-gating mutants of a rhomboid intramembrane protease display increased activity in living cells

Sinisa Urban, Rosanna P. Baker

Biol Chem. Author manuscript; available in PMC 2009 Aug 1.

Published in final edited form as: Biol Chem. 2008 Aug; 389(8): 1107–1115. doi: 10.1515/BC.2008.122

PMCID:: PMC2678756

Article PDF–1.2M

Select item 212886713.

The role of L1 loop in the mechanism of rhomboid intramembrane protease GlpG

Yongcheng Wang, Saki Maegawa, Yoshinori Akiyama, Ya Ha

J Mol Biol. Author manuscript; available in PMC 2008 Dec 7.

Published in final edited form as: J Mol Biol. 2007 Dec 7; 374(4): 1104–1113. Published online 2007 Oct 11. doi: 10.1016/j.jmb.2007.10.014

PMCID:: PMC2128867

Article PDF–3.0M

Select item 204291514.

Structural principles of intramembrane proteases

Ya Ha

Curr Opin Struct Biol. Author manuscript; available in PMC 2008 Aug 1.

Published in final edited form as: Curr Opin Struct Biol. 2007 Aug; 17(4): 405–411. Published online 2007 Aug 21. doi: 10.1016/j.sbi.2007.06.010

PMCID:: PMC2042915

Article PDF–1.4M

Select item 189593815.

Enzymatic analysis of a rhomboid intramembrane protease implicates transmembrane helix 5 as the lateral substrate gate

Rosanna P. Baker, Keith Young, Liang Feng, Yigong Shi, Sinisa Urban

Proc Natl Acad Sci U S A. 2007 May 15; 104(20): 8257–8262. Published online 2007 Apr 26. doi: 10.1073/pnas.0700814104

PMCID:: PMC1895938

Article PDF–1.0M

Select item 189294616.

Open-cap conformation of intramembrane protease GlpG

Yongcheng Wang, Ya Ha

Proc Natl Acad Sci U S A. 2007 Feb 13; 104(7): 2098–2102. Published online 2007 Feb 2. doi: 10.1073/pnas.0611080104

PMCID:: PMC1892946

Article PDF–2.1M

Select item 176640717.

Structural basis for intramembrane proteolysis by rhomboid serine proteases

Adam Ben-Shem, Deborah Fass, Eitan Bibi

Proc Natl Acad Sci U S A. 2007 Jan 9; 104(2): 462–466. Published online 2006 Dec 26. doi: 10.1073/pnas.0609773104

PMCID:: PMC1766407

Article PDF–3.0M

Select item 168148118.

Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110

Koji Hayashi, Naoki Morooka, Yoshihiro Yamamoto, Katsutoshi Fujita, Katsumi Isono, Sunju Choi, Eiichi Ohtsubo, Tomoya Baba, Barry L Wanner, Hirotada Mori, Takashi Horiuchi

Mol Syst Biol. 2006; 2: 2006.0007. Published online 2006 Feb 21. doi: 10.1038/msb4100049