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Items: 1 to 20 of 34

1.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
2.
Human fetal liver metabolism of oxycodone is mediated by CYP3A7
Sara Shum, Nina Isoherranen
AAPS J. Author manuscript; available in PMC 2022 Jan 12.
Published in final edited form as: AAPS J. 2021 Jan 12; 23(1): 24. Published online 2021 Jan 12. doi: 10.1208/s12248-020-00537-x
PMCID:
PMC8106324
AbstractArticlePDF–689K
3.
Associations Between Cytochrome P450 (CYP) Gene Single-Nucleotide Polymorphisms and Second-to-Fourth Digit Ratio in Chinese University Students
Jing Zhang, Mengyi Yang, Pengfei Luan, Wei Jia, Qiujun Liu, Zhanbing Ma, Jie Dang, Hong Lu, Qian Ma, Yanfeng Wang, Chunlan Mu, Zhenghao Huo
Med Sci Monit. 2021; 27: e930591-1–e930591-13. Prepublished online 2021 Mar 3. Published online 2021 Mar 16. doi: 10.12659/MSM.930591
PMCID:
PMC7980499
AbstractArticlePDF–1.8M
4.
CYP3A7*1C allele: linking premenopausal oestrone and progesterone levels with risk of hormone receptor-positive breast cancers
Nichola Johnson, Sarah Maguire, Anna Morra, Pooja Middha Kapoor, Katarzyna Tomczyk, Michael E. Jones, Minouk J. Schoemaker, Clare Gilham, Manjeet K. Bolla, Qin Wang, Joe Dennis, Thomas U. Ahearn, Irene L. Andrulis, Hoda Anton-Culver, Natalia N. Antonenkova, Volker Arndt, Kristan J. Aronson, Annelie Augustinsson, Caroline Baynes, Laura E. Beane Freeman, Matthias W. Beckmann, Javier Benitez, Marina Bermisheva, Carl Blomqvist, Bram Boeckx, Natalia V. Bogdanova, Stig E. Bojesen, Hiltrud Brauch, Hermann Brenner, Barbara Burwinkel, Daniele Campa, Federico Canzian, Jose E. Castelao, Stephen J. Chanock, Georgia Chenevix-Trench, Christine L. Clarke, NBCS Collaborators, Don M. Conroy, Fergus J. Couch, Angela Cox, Simon S. Cross, Kamila Czene, Thilo Dörk, A. Heather Eliassen, Christoph Engel, D. Gareth Evans, Peter A. Fasching, Jonine Figueroa, Giuseppe Floris, Henrik Flyger, Manuela Gago-Dominguez, Susan M. Gapstur, Montserrat García-Closas, Mia M. Gaudet, Graham G. Giles, Mark S. Goldberg, Anna González-Neira, AOCS Group, Pascal Guénel, Eric Hahnen, Christopher A. Haiman, Niclas Håkansson, Per Hall, Ute Hamann, Patricia A. Harrington, Steven N. Hart, Maartje J. Hooning, John L. Hopper, Anthony Howell, David J. Hunter, ABCTB Investigators, kConFab Investigators, Agnes Jager, Anna Jakubowska, Esther M. John, Rudolf Kaaks, Renske Keeman, Elza Khusnutdinova, Cari M. Kitahara, Veli-Matti Kosma, Stella Koutros, Peter Kraft, Vessela N. Kristensen, Allison W. Kurian, Diether Lambrechts, Loic Le Marchand, Martha Linet, Jan Lubiński, Arto Mannermaa, Siranoush Manoukian, Sara Margolin, John W. M. Martens, Dimitrios Mavroudis, Rebecca Mayes, Alfons Meindl, Roger L. Milne, Susan L. Neuhausen, Heli Nevanlinna, William G. Newman, Sune F. Nielsen, Børge G. Nordestgaard, Nadia Obi, Andrew F. Olshan, Janet E. Olson, Håkan Olsson, Ester Orban, Tjoung-Won Park-Simon, Paolo Peterlongo, Dijana Plaseska-Karanfilska, Katri Pylkäs, Gad Rennert, Hedy S. Rennert, Kathryn J. Ruddy, Emmanouil Saloustros, Dale P. Sandler, Elinor J. Sawyer, Rita K. Schmutzler, Christopher Scott, Xiao-Ou Shu, Jacques Simard, Snezhana Smichkoska, Christof Sohn, Melissa C. Southey, John J. Spinelli, Jennifer Stone, Rulla M. Tamimi, Jack A. Taylor, Rob A. E. M. Tollenaar, Ian Tomlinson, Melissa A. Troester, Thérèse Truong, Celine M. Vachon, Elke M. van Veen, Sophia S. Wang, Clarice R. Weinberg, Camilla Wendt, Hans Wildiers, Robert Winqvist, Alicja Wolk, Wei Zheng, Argyrios Ziogas, Alison M. Dunning, Paul D. P. Pharoah, Douglas F. Easton, A. Forbes Howie, Julian Peto, Isabel dos-Santos-Silva, Anthony J. Swerdlow, Jenny Chang-Claude, Marjanka K. Schmidt, Nick Orr, Olivia Fletcher
Br J Cancer. 2021 Feb 16; 124(4): 842–854. Published online 2021 Jan 26. doi: 10.1038/s41416-020-01185-w
PMCID:
PMC7884683
AbstractArticlePDF–969K
5.
Neonatal cytochrome P450 CYP3A7: A comprehensive review of its role in development, disease, and xenobiotic metabolism
Haixing Li, Jed N. Lampe
Arch Biochem Biophys. Author manuscript; available in PMC 2020 Sep 30.
Published in final edited form as: Arch Biochem Biophys. 2019 Sep 30; 673: 108078. Published online 2019 Aug 22. doi: 10.1016/j.abb.2019.108078
PMCID:
PMC6739124
AbstractArticlePDF–641K
6.
Stereoselective Oxidation Kinetics of Deoxycholate in Recombinant and Microsomal CYP3A Enzymes: Deoxycholate 19-Hydroxylation Is an In Vitro Marker of CYP3A7 Activity
Yu-Jie Chen, Jian Zhang, Ping-Ping Zhu, Xian-Wen Tan, Qiu-Hong Lin, Wen-Xia Wang, Shan-Shan Yin, Ling-Zhi Gao, Ming-Ming Su, Chang-Xiao Liu, Liang Xu, Wei Jia, Irina F. Sevrioukova, Ke Lan
Drug Metab Dispos. 2019 Jun; 47(6): 574–581. Published online 2019 Jun. doi: 10.1124/dmd.119.086637
PMCID:
PMC6505377
AbstractArticlePDF–1.0M
7.
Scaling in vitro activity of CYP3A7 suggests human fetal livers do not clear retinoic acid entering from maternal circulation
Ariel R. Topletz, Guo Zhong, Nina Isoherranen
Sci Rep. 2019; 9: 4620. Published online 2019 Mar 15. doi: 10.1038/s41598-019-40995-8
PMCID:
PMC6420499
AbstractArticlePDF–1.9M
8.
Whole exome sequencing for the identification of CYP3A7 variants associated with tacrolimus concentrations in kidney transplant patients
Minji Sohn, Myeong Gyu Kim, Nayoung Han, In-Wha Kim, Jungsoo Gim, Sang-Il Min, Eun Young Song, Yon Su Kim, Hun Soon Jung, Young Kee Shin, Jongwon Ha, Jung Mi Oh
Sci Rep. 2018; 8: 18064. Published online 2018 Dec 24. doi: 10.1038/s41598-018-36085-w
Correction in:
Sci Rep. 2020; 10: 2486.
PMCID:
PMC6305386
AbstractArticlePDF–1.6M
9.
Digging Deeper into CYP3A Testosterone Metabolism: Kinetic, Regioselectivity, and Stereoselectivity Differences between CYP3A4/5 and CYP3A7
Sylvie E. Kandel, Lyrialle W. Han, Qingcheng Mao, Jed N. Lampe
Drug Metab Dispos. 2017 Dec; 45(12): 1266–1275. Published online 2017 Dec. doi: 10.1124/dmd.117.078055
PMCID:
PMC5697443
AbstractArticlePDF–1.1M
10.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
11.
CYP3A genes and the association between prenatal methylmercury exposure and neurodevelopment
Sabrina Llop, Van Tran, Ferran Ballester, Fabio Barbone, Aikaterini Sofianou-Katsoulis, Jordi Sunyer, Karin Engström, Ayman Alhamdow, Tanzy M Love, Gene E Watson, Mariona Bustamante, Mario Murcia, Carmen Iñiguez, Conrad F Shamlaye, Valentina Rosolen, Marika Mariuz, Milena Horvat, Janja S Tratnik, Darja Mazej, Edwin van Wijngaarden, Philip W Davidson, Gary J Myers, Matthew D Rand, Karin Broberg
Environ Int. Author manuscript; available in PMC 2018 Aug 1.
Published in final edited form as: Environ Int. 2017 Aug; 105: 34–42. Published online 2017 May 10. doi: 10.1016/j.envint.2017.04.013
PMCID:
PMC5517297
AbstractArticlePDF–805K
12.
CYP3A7*1C allele is associated with reduced levels of 2-hydroxylation pathway oestrogen metabolites
Deepti Sood, Nichola Johnson, Pooja Jain, Alexandros P Siskos, Mark Bennett, Clare Gilham, Marta Cecilia Busana, Julian Peto, Isabel dos-Santos-Silva, Hector C Keun, Olivia Fletcher
Br J Cancer. 2017 Jan 31; 116(3): 382–388. Published online 2017 Jan 10. doi: 10.1038/bjc.2016.432
PMCID:
PMC5294487
AbstractArticlePDF–595K
13.
Immunohistochemical Markers of CYP3A4 and CYP3A7: A New Tool Towards Personalized Pharmacotherapy of Hepatocellular Carcinoma
D. Fanni, M. Manchia, F. Lai, C. Gerosa, R. Ambu, G. Faa
Eur J Histochem. 2016 Apr 11; 60(2): 2614. Published online 2016 Apr 11. doi: 10.4081/ejh.2016.2614
PMCID:
PMC4933826
AbstractArticlePDF–496K
14.
Role of Chromatin Structural Changes in Regulating Human CYP3A Ontogeny
Nicholas L. Giebel, Jeffrey D. Shadley, D. Gail McCarver, Kenneth Dorko, Roberto Gramignoli, Stephen C. Strom, Ke Yan, Pippa M. Simpson, Ronald N. Hines
Drug Metab Dispos. 2016 Jul; 44(7): 1027–1037. Published online 2016 Jul. doi: 10.1124/dmd.116.069344
PMCID:
PMC4931893
AbstractArticlePDF–891K
15.
Cytochrome P450 allele CYP3A7*1C associates with adverse outcomes in chronic lymphocytic leukemia, breast and lung cancer
Nichola Johnson, Paolo De Ieso, Gabriele Migliorini, Nick Orr, Peter Broderick, Daniel Catovsky, Athena Matakidou, Timothy Eisen, Christy Goldsmith, Frank Dudbridge, Julian Peto, Isabel dos-Santos-Silva, Alan Ashworth, Gillian Ross, Richard S Houlston, Olivia Fletcher
Cancer Res. Author manuscript; available in PMC 2016 Sep 15.
Published in final edited form as: Cancer Res. 2016 Mar 15; 76(6): 1485–1493. doi: 10.1158/0008-5472.CAN-15-1410
PMCID:
PMC4795533
AbstractArticlePDF–628K
16.
Histopathology of melanosis coli and determination of its associated genes by comparative analysisof expression microarrays
XIAO-AN LI, YAN ZHOU, SHU-XIAN ZHOU, HAI-RONG LIU, JIN-MEI XU, LONG GAO, XIAN-JING YU, XIAO-HUI LI
Mol Med Rep. 2015 Oct; 12(4): 5807–5815. Published online 2015 Jul 27. doi: 10.3892/mmr.2015.4126
PMCID:
PMC4581826
AbstractArticlePDF–1.4M
17.
CBFβ stabilizes HIV Vif to counteract APOBEC3 at the expense of RUNX1 target gene expression
Dong Young Kim, Eunju Kwon, Paul D. Hartley, David C. Crosby, Sumanjit Mann, Nevan J. Krogan, John D. Gross
Mol Cell. Author manuscript; available in PMC 2014 Feb 21.
Published in final edited form as: Mol Cell. 2013 Feb 21; 49(4): 632–644. Published online 2013 Jan 17. doi: 10.1016/j.molcel.2012.12.012
PMCID:
PMC3582769
AbstractArticlePDF–4.5M
18.
Metabolic Pathways of Inhaled Glucocorticoids by the CYP3A Enzymes
Chad D. Moore, Jessica K. Roberts, Christopher R. Orton, Takahiro Murai, Trevor P. Fidler, Christopher A. Reilly, Robert M. Ward, Garold S. Yost
Drug Metab Dispos. 2013 Feb; 41(2): 379–389. Published online 2013 Feb. doi: 10.1124/dmd.112.046318
PMCID:
PMC3558858
AbstractArticlePDF–930K
19.
Expression and Regulation of Human Fetal-Specific CYP3A7 in Mice
Xiao-Yan Pang, Jie Cheng, Jung-Hwan Kim, Tsutomu Matsubara, Kristopher W. Krausz, Frank J. Gonzalez
Endocrinology. 2012 Mar; 153(3): 1453–1463. Published online 2012 Jan 17. doi: 10.1210/en.2011-1020
PMCID:
PMC3281537
AbstractArticle
20.
Genetic Susceptibility to Distinct Bladder Cancer Subphenotypes
Lin T. Guey, Montserrat García-Closas, Cristiane Murta-Nascimento, Josep Lloreta, Laia Palencia, Manolis Kogevinas, Nathaniel Rothman, Gemma Vellalta, Malu Calle, Gaëlle Marenne, Adonina Tardón, Alfredo Carrato, Reina García-Closas, Consol Serra, Debra T Silverman, Stephen Chanock, Francisco X. Real, Núria Malats
Eur Urol. Author manuscript; available in PMC 2011 Nov 18.
Published in final edited form as: Eur Urol. 2010 Feb; 57(2): 283–292. Published online 2009 Aug 12. doi: 10.1016/j.eururo.2009.08.001
PMCID:
PMC3220186
AbstractArticlePDF–595K

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