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Select item 114802031.

A non-canonical repressor function of JUN restrains YAP activity and liver cancer growth

Yuliya Kurlishchuk, Anita Cindric Vranesic, Marco Jessen, Alexandra Kipping, Christin Ritter, KyungMok Kim, Paul Cramer, Björn von Eyss

EMBO J. 2024 Oct; 43(20): 4578–4603. Published online 2024 Aug 29. doi: 10.1038/s44318-024-00188-0

PMCID:: PMC11480203

Abstract Article PDF–6.3M

Select item 113159292.

A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex

Marisa Bedir, Emily Outwin, Rita Colnaghi, Lydia Bassett, Iga Abramowicz, Mark O’Driscoll

EMBO Rep. 2024 Aug; 25(8): 3432–3455. Published online 2024 Jun 28. doi: 10.1038/s44319-024-00184-9

PMCID:: PMC11315929

Abstract Article PDF–3.4M

Select item 112099353.

Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability

Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson

Cell. Author manuscript; available in PMC 2024 Oct 26.

Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008

PMCID:: PMC11209935

Abstract Article PDF–3.0M

Select item 111625024.

FOXA2 rewires AP-1 for transcriptional reprogramming and lineage plasticity in prostate cancer

Zifeng Wang, Scott L. Townley, Songqi Zhang, Mingyu Liu, Muqing Li, Maryam Labaf, Susan Patalano, Kavita Venkataramani, Kellee R. Siegfried, Jill A. Macoska, Dong Han, Shuai Gao, Gail P. Risbridger, Renea A. Taylor, Mitchell G. Lawrence, Housheng Hansen He, Luke A. Selth, Changmeng Cai

Nat Commun. 2024; 15: 4914. Published online 2024 Jun 8. doi: 10.1038/s41467-024-49234-9

PMCID:: PMC11162502

Abstract Article PDF–6.5M

Select item 111599365.

ZAK inhibits human lung cancer cell growth via ERK and JNK activation in an AP‐1‐dependent manner

Jaw‐Ji Yang, Yi‐Ju Lee, Hsin‐Hung Hung, Wei‐Pu Tseng, Chuan‐Chou Tu, Huei Lee, Wen‐Jun Wu

Cancer Sci. 2010 Jun; 101(6): 1374–1381. Published online 2010 Feb 18. doi: 10.1111/j.1349-7006.2010.01537.x

PMCID:: PMC11159936

Abstract Article PDF–637K

Select item 111548416.

SIAH2 suppresses c‐JUN pathway by promoting the polyubiquitination and degradation of HBx in hepatocellular carcinoma

Qinghe Hu, Zhiyi Liu, Yao Liu, Jie Qiu, Xue Zhang, Jun Sun, Bin Zhang, Hengliang Shi

J Cell Mol Med. 2024 Jun; 28(11): e18484. Published online 2024 Jun 6. doi: 10.1111/jcmm.18484

PMCID:: PMC11154841

Abstract Article PDF–13M

Select item 111471027.

Nuclear translocation of Fos is stimulated by interaction with Jun through the leucine zipper

K. Chida, S. Nagamori, T. Kuroki

Cell Mol Life Sci. 1999 Feb; 55(2): 297–302. Published online 2014 Jan 30. doi: 10.1007/s000180050291

PMCID:: PMC11147102

Abstract Article PDF–350K

Select item 111155558.

Involvement of aryl hydrocarbon receptor nuclear translocator in EGF-induced c-Jun/Sp1-mediated gene expression

Wan-Chen Huang, Shu-Ting Chen, Wei-Chiao Chang, Kwang-Yu Chang, Wen-Chang Chang, Ben-Kuen Chen

Cell Mol Life Sci. 2010 Oct; 67(20): 3523–3533. Published online 2010 May 28. doi: 10.1007/s00018-010-0392-9

PMCID:: PMC11115555

Abstract Article PDF–591K

Select item 110718869.

Integrative epigenetic analysis reveals AP-1 promotes activation of tumor-infiltrating regulatory T cells in HCC

Baowen Zhuo, Qifan Zhang, Tingyan Xie, Yidan Wang, Zhengliang Chen, Daming Zuo, Bo Guo

Cell Mol Life Sci. 2023 Apr; 80(4): 103. Published online 2023 Mar 20. doi: 10.1007/s00018-023-04746-3

PMCID:: PMC11071886

Abstract Article PDF–11M

Select item 1100647010.

Single cell RNA-seq identifies a FOS/JUN-related monocyte signature associated with clinical response of heart failure patients with mesenchymal stem cell therapy

Hui Yuan, Pengfei Zhang, Yuanfeng Xin, Zhongmin Liu, Bingren Gao

Aging (Albany NY) 2024 Mar 31; 16(6): 5651–5675. Published online 2024 Mar 20. doi: 10.18632/aging.205670

PMCID:: PMC11006470

Abstract Article PDF–9.7M

Select item 1086980011.

The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation

Christopher B. Nelson, Samuel Rogers, Kaushik Roychoudhury, Yaw Sing Tan, Caroline J. Atkinson, Alexander P. Sobinoff, Christopher G. Tomlinson, Anton Hsu, Robert Lu, Eloise Dray, Michelle Haber, Jamie I. Fletcher, Anthony J. Cesare, Rashmi S. Hegde, Hilda A. Pickett

Nat Commun. 2024; 15: 1385. Published online 2024 Feb 15. doi: 10.1038/s41467-024-45683-4

PMCID:: PMC10869800

Abstract Article PDF–9.3M

Select item 1083829012.

ANKRD1 is a mesenchymal-specific driver of cancer-associated fibroblast activation bridging androgen receptor loss to AP-1 activation

Luigi Mazzeo, Soumitra Ghosh, Emery Di Cicco, Jovan Isma, Daniele Tavernari, Anastasia Samarkina, Paola Ostano, Markus K. Youssef, Christian Simon, G. Paolo Dotto

Nat Commun. 2024; 15: 1038. Published online 2024 Feb 3. doi: 10.1038/s41467-024-45308-w

PMCID:: PMC10838290

Abstract Article PDF–6.2M

Select item 1068032713.

Cooperation of MLL1 and Jun in controlling H3K4me3 on enhancers in colorectal cancer

Xiang Lin, Ji-Dong Chen, Chen-Yu Wang, Zhen Cai, Rui Zhan, Chen Yang, La-Ying Zhang, Lian-Yun Li, Yong Xiao, Ming-Kai Chen, Min Wu

Genome Biol. 2023; 24: 268. Published online 2023 Nov 27. doi: 10.1186/s13059-023-03108-3

PMCID:: PMC10680327

Abstract Article PDF–6.7M

Select item 1065588614.

Jun-APOE-LRP1 axis promotes tumor metastasis in colorectal cancer

Lingyuan He, Mengchen Shi, Shuwei Ren, Jingdan Zhang, Yu Tian, Xiangling Yang, Huanliang Liu

Biomol Biomed. 2023 Dec 1; 23(6): 1026–1037. Published online 2023 Dec 1. doi: 10.17305/bb.2023.9248

PMCID:: PMC10655886

Abstract Article PDF–3.0M

Select item 1060682015.

Thrombin-Induced COX-2 Expression and PGE₂ Synthesis in Human Tracheal Smooth Muscle Cells: Role of PKCδ/Pyk2-Dependent AP-1 Pathway Modulation

Chien-Chung Yang, I-Ta Lee, Yan-Jyun Lin, Wen-Bin Wu, Li-Der Hsiao, Chuen-Mao Yang

Int J Mol Sci. 2023 Oct; 24(20): 15130. Published online 2023 Oct 13. doi: 10.3390/ijms242015130

PMCID:: PMC10606820

Abstract Article PDF–5.9M

Select item 1056587616.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644

PMCID:: PMC10565876

Abstract Article PDF–3.7M

Select item 1046073217.

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4

Wenhu Chen, Liqiang Hu, Xuemei Lu, Xiaofei Wang, Changan Zhao, Chen Guo, Xiaoyan Li, Yuqin Ding, Hongguang Zhao, Dongdong Tong, Lifang Wang, Chen Huang

Breast Cancer Res Treat. 2023; 201(3): 353–366. Published online 2023 Jul 11. doi: 10.1007/s10549-023-07028-5

PMCID:: PMC10460732

Abstract Article PDF–5.6M

Select item 1044293618.

c-JUN is a barrier in hESC to cardiomyocyte transition

Hui Zhong, Ran Zhang, Guihuan Li, Ping Huang, Yudan Zhang, Jieying Zhu, Junqi Kuang, Andrew P Hutchins, Dajiang Qin, Ping Zhu, Duanqing Pei, Dongwei Li

Life Sci Alliance. 2023 Nov; 6(11): e202302121. Published online 2023 Aug 21. doi: 10.26508/lsa.202302121

PMCID:: PMC10442936

Abstract Article PDF–3.8M

Select item 1033388419.

Large‐scale phosphomimetic screening identifies phospho‐modulated motif‐based protein interactions

Johanna Kliche, Dimitriya Hristoforova Garvanska, Leandro Simonetti, Dilip Badgujar, Doreen Dobritzsch, Jakob Nilsson, Norman E Davey, Ylva Ivarsson

Mol Syst Biol. 2023 Jul; 19(7): e11164. Published online 2023 May 23. doi: 10.15252/msb.202211164

PMCID:: PMC10333884

Abstract Article PDF–5.0M

Select item 1017909720.

Interleukin-1ß Attenuates Expression of Augmenter of Liver Regeneration (ALR) by Regulating HNF4α Independent of c-Jun

Jonas Nimphy, Sara Ibrahim, Rania Dayoub, Marion Kubitza, Michael Melter, Thomas S. Weiss

Int J Mol Sci. 2023 May; 24(9): 8107. Published online 2023 Apr 30. doi: 10.3390/ijms24098107

PMCID:: PMC10179097

Abstract Article PDF–2.5M

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