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Select item 113617481.

Repeated stress to the skin amplifies neutrophil infiltration in a keratin 17- and PKCα-dependent manner

Yang Xu, Erez Cohen, Craig N. Johnson, Carole A. Parent, Pierre A. Coulombe

PLoS Biol. 2024 Aug; 22(8): e3002779. Published online 2024 Aug 19. doi: 10.1371/journal.pbio.3002779

PMCID:: PMC11361748

Abstract Article PDF–6.3M

Select item 110872492.

Keratin 17 modulates the immune topography of pancreatic cancer

Lyanne Delgado-Coka, Michael Horowitz, Mariana Torrente-Goncalves, Lucia Roa-Peña, Cindy V. Leiton, Mahmudul Hasan, Sruthi Babu, Danielle Fassler, Jaymie Oentoro, Ji-Dong K Bai, Emanuel F. Petricoin, III, Lynn M. Matrisian, Edik Matthew Blais, Natalia Marchenko, Felicia D. Allard, Wei Jiang, Brent Larson, Andrew Hendifar, Chao Chen, Shahira Abousamra, Dimitris Samaras, Tahsin Kurc, Joel Saltz, Luisa F. Escobar-Hoyos, Kenneth R. Shroyer

J Transl Med. 2024; 22: 443. Published online 2024 May 10. doi: 10.1186/s12967-024-05252-1

PMCID:: PMC11087249

Abstract Article PDF–1.5M

Select item 107649583.

TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence

Jiang Ren, Shuai Wang, Zhi Zong, Ting Pan, Sijia Liu, Wei Mao, Huizhe Huang, Xiaohua Yan, Bing Yang, Xin He, Fangfang Zhou, Long Zhang

Nat Commun. 2024; 15: 244. Published online 2024 Jan 4. doi: 10.1038/s41467-023-44502-6

PMCID:: PMC10764958

Abstract Article PDF–4.4M

Select item 107482334.

Emerging Prognostic and Predictive Significance of Stress Keratin 17 in HPV-Associated and Non HPV-Associated Human Cancers: A Scoping Review

Taja Lozar, Wei Wang, Niki Gavrielatou, Leslie Christensen, Paul F. Lambert, Paul M. Harari, David L. Rimm, Barbara Burtness, Cvetka Grasic Kuhar, Evie H. Carchman

Viruses. 2023 Dec; 15(12): 2320. Published online 2023 Nov 25. doi: 10.3390/v15122320

PMCID:: PMC10748233

Abstract Article PDF–2.1M

Select item 105041565.

Interference KRT17 reverses doxorubicin resistance in triple-negative breast cancer cells by Wnt/β-catenin signaling pathway

Liqiong Wu, Wenshuang Ding, Xiaopai Wang, Xiubo Li, Jing Yang

Genes Genomics. 2023; 45(10): 1329–1338. Published online 2023 Aug 27. doi: 10.1007/s13258-023-01437-y

PMCID:: PMC10504156

Abstract Article PDF–8.7M

Select item 103675546.

Keratin 17 covalently binds to alpha-enolase and exacerbates proliferation of keratinocytes in psoriasis

Yixin Luo, Bingyu Pang, Junfeng Hao, Qingyang Li, Pei Qiao, Chen Zhang, Yaxing Bai, Chunying Xiao, Jiaoling Chen, Dalong Zhi, Ying Liu, Erle Dang, Gang Wang, Bing Li

Int J Biol Sci. 2023; 19(11): 3395–3411. Published online 2023 Jul 3. doi: 10.7150/ijbs.83141

PMCID:: PMC10367554

Abstract Article PDF–16M

Select item 103206897.

KRT17 Promotes T-lymphocyte Infiltration Through the YTHDF2–CXCL10 Axis in Colorectal Cancer

Wenfeng Liang, Huashan Liu, Ziwei Zeng, Zhenxing Liang, Hao Xie, Wenxin Li, Li Xiong, Zhihang Liu, Mian Chen, Haiqing Jie, Xiaobin Zheng, Liang Huang, Liang Kang

Cancer Immunol Res. 2023 Jul 5; 11(7): 875–894. Published online 2023 May 2. doi: 10.1158/2326-6066.CIR-22-0814

PMCID:: PMC10320689

Abstract Article PDF–18M

Select item 102431548.

Ring finger protein 12 activates AKT signalling to promote the progression of liver cancer by interacting with EGFR

Chengpeng Yu, Dean Rao, Tiantian Wang, Jiaqi Sheng, Enjun Lv, Long Zhang, Xun Lu, Jingjing Yu, Huifang Liang, Jia Song, Wenjie Huang

J Cell Mol Med. 2023 Jun; 27(11): 1523–1538. Published online 2023 May 2. doi: 10.1111/jcmm.17757

PMCID:: PMC10243154

Abstract Article PDF–51M

Select item 102374229.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 1015161510.

Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell

Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low

Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120

PMCID:: PMC10151615

Abstract Article PDF–2.9M

Select item 1014884311.

mTORC2 interactome and localization determine aggressiveness of high-grade glioma cells through association with gelsolin

Naphat Chantaravisoot, Piriya Wongkongkathep, Nuttiya Kalpongnukul, Narawit Pacharakullanon, Pornchai Kaewsapsak, Chaiyaboot Ariyachet, Joseph A. Loo, Fuyuhiko Tamanoi, Trairak Pisitkun

Sci Rep. 2023; 13: 7037. Published online 2023 Apr 29. doi: 10.1038/s41598-023-33872-y

PMCID:: PMC10148843

Abstract Article PDF–11M

Select item 997119512.

CEMIP, acting as a scaffold protein for bridging GRAF1 and MIB1, promotes colorectal cancer metastasis via activating CDC42/MAPK pathway

Guojie Xu, Lei Zhao, Qingling Hua, Lanqing Wang, Hongli Liu, Zhenyu Lin, Min Jin, Jing Wang, Pengfei Zhou, Kunyu Yang, Gang Wu, Dandan Yu, Dejun Zhang, Tao Zhang

Cell Death Dis. 2023 Feb; 14(2): 167. Published online 2023 Feb 27. doi: 10.1038/s41419-023-05644-z

PMCID:: PMC9971195

Abstract Article PDF–15M

Select item 995044713.

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma

Yu-Fei Cao, Lei Xie, Bei-Bei Tong, Man-Yu Chu, Wen-Qi Shi, Xiang Li, Jian-Zhong He, Shao-Hong Wang, Zhi-Yong Wu, Dan-Xia Deng, Ya-Qi Zheng, Zhi-Mao Li, Xiu-E Xu, Lian-Di Liao, Yin-Wei Cheng, Li-Yan Li, Li-Yan Xu, En-Min Li

Cell Death Differ. 2023 Feb; 30(2): 527–543. Published online 2022 Dec 16. doi: 10.1038/s41418-022-01104-x

PMCID:: PMC9950447

Abstract Article PDF–8.4M

Select item 978132314.

Engagement of the G3BP2-TRIM25 Interaction by Nucleocapsid Protein Suppresses the Type I Interferon Response in SARS-CoV-2-Infected Cells

Zening Yang, Jing Li, Jiali Li, Huiwen Zheng, Heng Li, Qingrun Lai, Yanli Chen, Li Qin, Yuanyuan Zuo, Lei Guo, Haijing Shi, Longding Liu

Vaccines (Basel) 2022 Dec; 10(12): 2042. Published online 2022 Nov 29. doi: 10.3390/vaccines10122042

PMCID:: PMC9781323

Abstract Article PDF–22M

Select item 974196715.

DDX24 promotes metastasis by regulating RPL5 in non‐small cell lung cancer

Xinyan Hu, Fangfang Li, Yulan Zhou, Hairun Gan, Tiancheng Wang, Luting Li, Haoyu Long, Bing Li, Pengfei Pang

Cancer Med. 2022 Dec; 11(23): 4513–4525. Published online 2022 Jul 21. doi: 10.1002/cam4.4835

PMCID:: PMC9741967

Abstract Article PDF–25M

Select item 952752016.

EGFR suppresses p53 function by promoting p53 binding to DNA-PKcs: a noncanonical regulatory axis between EGFR and wild-type p53 in glioblastoma

Jie Ding, Xiaolong Li, Sabbir Khan, Chen Zhang, Feng Gao, Shayak Sen, Amanda R Wasylishen, Yang Zhao, Guillermina Lozano, Dimpy Koul, W K Alfred Yung

Neuro Oncol. 2022 Oct; 24(10): 1712–1725. Published online 2022 Apr 26. doi: 10.1093/neuonc/noac105

PMCID:: PMC9527520

Abstract Article PDF–12M

Select item 952399717.

MBD5 and MBD6 stabilize the BAP1 complex and promote BAP1-dependent cancer

Natsumi Tsuboyama, Aileen Patricia Szczepanski, Zibo Zhao, Lu Wang

Genome Biol. 2022; 23: 206. Published online 2022 Sep 30. doi: 10.1186/s13059-022-02776-x

PMCID:: PMC9523997

Abstract Article PDF–6.9M

Select item 949615618.

Reduced Expression of KRT17 Predicts Poor Prognosis in HER2^high Breast Cancer

Shasha Tang, Wenjing Liu, Liyun Yong, Dongyang Liu, Xiaoyan Lin, Yuan Huang, Hui Wang, Fengfeng Cai

Biomolecules. 2022 Sep; 12(9): 1183. Published online 2022 Aug 25. doi: 10.3390/biom12091183

PMCID:: PMC9496156

Abstract Article PDF–1.8M

Select item 946166419.

PHGDH Inhibits Ferroptosis and Promotes Malignant Progression by Upregulating SLC7A11 in Bladder Cancer

Liliang Shen, Junfeng Zhang, Zongtai Zheng, Fuhan Yang, Shenghua Liu, Yuan Wu, Yifan Chen, Tianyuan Xu, Shiyu Mao, Yang Yan, Wei Li, Wentao Zhang, Xudong Yao

Int J Biol Sci. 2022; 18(14): 5459–5474. Published online 2022 Aug 29. doi: 10.7150/ijbs.74546

PMCID:: PMC9461664

Abstract Article PDF–3.5M

Select item 944496520.

Cytokeratins 5 and 17 maintain an aggressive epithelial state in basal-like breast cancer

Olivia McGinn, Duncan Riley, Jessica Finlay-Schultz, Kiran V. Paul, Peter Kabos, Carol A. Sartorius

Mol Cancer Res. Author manuscript; available in PMC 2023 Mar 2.

Published in final edited form as: Mol Cancer Res. 2022 Sep 2; 20(9): 1443–1455. doi: 10.1158/1541-7786.MCR-21-0866

PMCID:: PMC9444965

Abstract Article PDF–2.3M

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