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Select item 103916751.

The tardigrade Dsup protein enhances radioresistance in Drosophila melanogaster and acts as an unspecific repressor of transcription

Mikhail Zarubin, Talyana Azorskaya, Olga Kuldoshina, Sergey Alekseev, Semen Mitrofanov, Elena Kravchenko

iScience. 2023 Jul 21; 26(7): 106998. Published online 2023 May 29. doi: 10.1016/j.isci.2023.106998

PMCID:: PMC10391675

Abstract Article PDF–3.0M

Select item 102641572.

Downregulation of Hsp90 and the Antimicrobial Peptide Mtk Suppresses Poly(GR)-Induced Neurotoxicity in C9ORF72-ALS/FTD

Soojin Lee, Yong-Woo Jun, Gabriel R. Linares, Brandon Butler, Yeliz Yuva-Adyemir, Jill Moore, Gopinath Krishnan, Bryan Ruiz-Juarez, Manuel Santana, Marine Pons, Neal Silverman, Zhiping Weng, Justin Ichida, Fen-Biao Gao

Neuron. Author manuscript; available in PMC 2024 May 3.

Published in final edited form as: Neuron. 2023 May 3; 111(9): 1381–1390.e6. Published online 2023 Mar 16. doi: 10.1016/j.neuron.2023.02.029

PMCID:: PMC10264157

Abstract Article PDF–1.9M

Select item 101927203.

HR repair pathway plays a crucial role in maintaining neural stem cell fate under irradiation stress

Xiao Xu, Huanping An, Cheng Wu, Rong Sang, Litao Wu, Yuhan Lou, Xiaohang Yang, Yongmei Xi

Life Sci Alliance. 2023 Aug; 6(8): e202201802. Published online 2023 May 17. doi: 10.26508/lsa.202201802

PMCID:: PMC10192720

Abstract Article PDF–2.9M

Select item 94408934.

Low dose rate γ-irradiation protects fruit fly chromosomes from double strand breaks and telomere fusions by reducing the esi-RNA biogenesis factor Loquacious

A. Porrazzo, F. Cipressa, A. De Gregorio, C. De Pittà, G. Sales, L. Ciapponi, P. Morciano, G. Esposito, M. A. Tabocchini, G. Cenci

Commun Biol. 2022; 5: 905. Published online 2022 Sep 3. doi: 10.1038/s42003-022-03885-w

Correction in:: Commun Biol. 2022; 5: 1033.

PMCID:: PMC9440893

Abstract Article PDF–2.8M

Select item 91447385.

Somatic Mobilization: High Somatic Insertion Rate of mariner Transposable Element in Drosophila simulans

Mariana Cancian, Tiago Minuzzi Freire da Fontoura Gomes, Elgion Lucio Silva Loreto

Insects. 2022 May; 13(5): 454. Published online 2022 May 12. doi: 10.3390/insects13050454

PMCID:: PMC9144738

Abstract Article PDF–2.5M

Select item 91434936.

Reduced Environmental Dose Rates Are Responsible for the Increased Susceptibility to Radiation-Induced DNA Damage in Larval Neuroblasts of Drosophila Grown inside the LNGS Underground Laboratory

Antonella Porrazzo, Giuseppe Esposito, Daniela Grifoni, Giovanni Cenci, Patrizia Morciano, Maria Antonella Tabocchini

Int J Mol Sci. 2022 May; 23(10): 5472. Published online 2022 May 13. doi: 10.3390/ijms23105472

PMCID:: PMC9143493

Abstract Article PDF–1.1M

Select item 85284897.

Multiscale analysis reveals that diet-dependent midgut plasticity emerges from alterations in both stem cell niche coupling and enterocyte size

Alessandro Bonfini, Adam J Dobson, David Duneau, Jonathan Revah, Xi Liu, Philip Houtz, Nicolas Buchon

eLife. 2021; 10: e64125. Published online 2021 Sep 23. doi: 10.7554/eLife.64125

PMCID:: PMC8528489

Abstract Article PDF–12M

Select item 82827498.

Polyploid mitosis and depolyploidization promote chromosomal instability and tumor progression in a Notch-induced tumor model

Xian-Feng Wang, Sheng-An Yang, Shangyu Gong, Chih-Hsuan Chang, Juan Martin Portilla, Deeptiman Chatterjee, Jerome Irianto, Hongcun Bao, Yi-Chun Huang, Wu-Min Deng

Dev Cell. Author manuscript; available in PMC 2022 Jul 12.

Published in final edited form as: Dev Cell. 2021 Jul 12; 56(13): 1976–1988.e4. Published online 2021 Jun 18. doi: 10.1016/j.devcel.2021.05.017

PMCID:: PMC8282749

Abstract Article PDF–3.2M

Select item 82197059.

The Atr-Chek1 pathway inhibits axon regeneration in response to Piezo-dependent mechanosensation

Feng Li, Tsz Y. Lo, Leann Miles, Qin Wang, Harun N. Noristani, Dan Li, Jingwen Niu, Shannon Trombley, Jessica I. Goldshteyn, Chuxi Wang, Shuchao Wang, Jingyun Qiu, Katarzyna Pogoda, Kalpana Mandal, Megan Brewster, Panteleimon Rompolas, Ye He, Paul A. Janmey, Gareth M. Thomas, Shuxin Li, Yuanquan Song

Nat Commun. 2021; 12: 3845. Published online 2021 Jun 22. doi: 10.1038/s41467-021-24131-7

PMCID:: PMC8219705

Abstract Article PDF–13M

Select item 785159610.

Genomics of Recombination Rate Variation in Temperature-Evolved Drosophila melanogaster Populations

Ari Winbush, Nadia D Singh

Genome Biol Evol. 2021 Jan; 13(1): evaa252. Published online 2020 Nov 28. doi: 10.1093/gbe/evaa252

PMCID:: PMC7851596

Abstract Article PDF–778K

Select item 742538711.

Attenuating the DNA damage response to double-strand breaks restores function in models of CNS neurodegeneration

Richard I Tuxworth, Matthew J Taylor, Ane Martin Anduaga, Alaa Hussien-Ali, Sotiroula Chatzimatthaiou, Joanne Longland, Adam M Thompson, Sharif Almutiri, Pavlos Alifragis, Charalambos P Kyriacou, Boris Kysela, Zubair Ahmed

Brain Commun. 2019; 1(1): fcz005. Published online 2019 Jul 2. doi: 10.1093/braincomms/fcz005

PMCID:: PMC7425387

Abstract Article PDF–1019K

Select item 696157812.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 691110413.

NBS1 interacts with HP1 to ensure genome integrity

Giuseppe Bosso, Francesca Cipressa, Maria Lina Moroni, Rosa Pennisi, Jacopo Albanesi, Valentina Brandi, Simona Cugusi, Fioranna Renda, Laura Ciapponi, Fabio Polticelli, Antonio Antoccia, Alessandra di Masi, Giovanni Cenci

Cell Death Dis. 2019 Dec; 10(12): 951. Published online 2019 Dec 13. doi: 10.1038/s41419-019-2185-x

PMCID:: PMC6911104

Abstract Article PDF–2.4M

Select item 650653914.

Tissue-specific (ts)CRISPR as an efficient strategy for in vivo screening in Drosophila

Hagar Meltzer, Efrat Marom, Idan Alyagor, Oded Mayseless, Victoria Berkun, Netta Segal-Gilboa, Tamar Unger, David Luginbuhl, Oren Schuldiner

Nat Commun. 2019; 10: 2113. Published online 2019 May 8. doi: 10.1038/s41467-019-10140-0

PMCID:: PMC6506539

Abstract Article PDF–6.5M

Select item 628631015.

Xrp1 is a transcription factor required for cell competition-driven elimination of loser cells

Ludovic Baillon, Federico Germani, Claudia Rockel, Jochen Hilchenbach, Konrad Basler

Sci Rep. 2018; 8: 17712. Published online 2018 Dec 7. doi: 10.1038/s41598-018-36277-4

PMCID:: PMC6286310

Abstract Article PDF–1.8M

Select item 605202316.

Caspases maintain tissue integrity by an apoptosis-independent inhibition of cell migration and invasion

Anna Gorelick-Ashkenazi, Ron Weiss, Lena Sapozhnikov, Anat Florentin, Lama Tarayrah-Ibraheim, Dima Dweik, Keren Yacobi-Sharon, Eli Arama

Nat Commun. 2018; 9: 2806. Published online 2018 Jul 18. doi: 10.1038/s41467-018-05204-6

PMCID:: PMC6052023

Abstract Article PDF–9.2M

Select item 590170317.

E2F/DP prevents cell cycle progression in endocycling fatbody cells by suppressing dATM expression

Ana Guarner, Robert Morris, Michael Korenjak, Myriam Boukhali, Maria Paula Zappia, Capucine Van Rechem, Johnathan R. Whetstine, Sridhar Ramaswamy, Lee Zou, Maxim V. Frolov, Wilhelm Haas, Nicholas J. Dyson

Dev Cell. Author manuscript; available in PMC 2018 Dec 18.

Published in final edited form as: Dev Cell. 2017 Dec 18; 43(6): 689–703.e5. Published online 2017 Dec 7. doi: 10.1016/j.devcel.2017.11.008

PMCID:: PMC5901703

Abstract Article PDF–2.1M

Select item 589268318.

Deficiency in DNA damage response of enterocytes accelerates intestinal stem cell aging in Drosophila

Joung-Sun Park, Ho-Jun Jeon, Jung-Hoon Pyo, Young-Shin Kim, Mi-Ae Yoo

Aging (Albany NY) 2018 Mar; 10(3): 322–338. Published online 2018 Mar 7. doi: 10.18632/aging.101390

PMCID:: PMC5892683

Abstract Article PDF–5.0M

Select item 577097519.

Regulation of Adult CNS Axonal Regeneration by the Post-transcriptional Regulator Cpeb1

Wilson Pak-Kin Lou, Alvaro Mateos, Marta Koch, Stefan Klussman, Chao Yang, Na Lu, Sachin Kumar, Stefanie Limpert, Manuel Göpferich, Marlen Zschaetzsch, Christopher Sliwinski, Marc Kenzelmann, Matthias Seedorf, Carlos Maillo, Elena Senis, Dirk Grimm, Radhika Puttagunta, Raul Mendez, Kai Liu, Bassem A. Hassan, Ana Martin-Villalba

Front Mol Neurosci. 2017; 10: 445. Published online 2018 Jan 12. doi: 10.3389/fnmol.2017.00445