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Select item 111632011.

DLK1/DIO3 locus upregulation by a β-catenin-dependent enhancer drives cell proliferation and liver tumorigenesis

Julie Sanceau, Lucie Poupel, Camille Joubel, Isabelle Lagoutte, Stefano Caruso, Sandra Pinto, Christèle Desbois-Mouthon, Cécile Godard, Akila Hamimi, Enzo Montmory, Cécile Dulary, Sophie Chantalat, Amélie Roehrig, Kevin Muret, Benjamin Saint-Pierre, Jean-François Deleuze, Sophie Mouillet-Richard, Thierry Forné, Christophe F. Grosset, Jessica Zucman-Rossi, Sabine Colnot, Angélique Gougelet

Mol Ther. 2024 Apr 3; 32(4): 1125–1143. Published online 2024 Feb 3. doi: 10.1016/j.ymthe.2024.01.036

PMCID:: PMC11163201

Abstract Article PDF–6.9M

Select item 111140452.

The microRNAs within the DLK1-DIO3 genomic region: involvement in disease pathogenesis

Leonidas Benetatos, Eleftheria Hatzimichael, Eric Londin, George Vartholomatos, Phillipe Loher, Isidore Rigoutsos, Evangelos Briasoulis

Cell Mol Life Sci. 2013 Mar; 70(5): 795–814. Published online 2012 Jul 24. doi: 10.1007/s00018-012-1080-8

PMCID:: PMC11114045

Abstract Article PDF–474K

Select item 110149073.

MiRNAs from the Dlk1-Dio3 locus and miR-224/452 cluster contribute to glioblastoma tumor heterogeneity

Christopher M. Smith, Daniel Catchpoole, Gyorgy Hutvagner

Sci Rep. 2024; 14: 8570. Published online 2024 Apr 13. doi: 10.1038/s41598-024-58870-6

PMCID:: PMC11014907

Abstract Article PDF–4.2M

Select item 108510884.

Pericardial delta like non‐canonical NOTCH ligand 1 (Dlk1) augments fibrosis in the heart through epithelial to mesenchymal transition

Charlotte Harken Jensen, Rikke Helin Johnsen, Tilde Eskildsen, Christina Baun, Ditte Gry Ellman, Shu Fang, Sara Thornby Bak, Svend Hvidsten, Lars Allan Larsen, Ann Mari Rosager, Lars Peter Riber, Mikael Schneider, Jo De Mey, Mads Thomassen, Mark Burton, Shizuka Uchida, Jorge Laborda, Ditte Caroline Andersen

Clin Transl Med. 2024 Feb; 14(2): e1565. Published online 2024 Feb 8. doi: 10.1002/ctm2.1565

PMCID:: PMC10851088

Abstract Article PDF–11M

Select item 97804325.

Circulating levels of DLK1 and glucose homeostasis in girls with obesity: A pilot study

Stefania Palumbo, Giuseppina Rosaria Umano, Francesca Aiello, Grazia Cirillo, Emanuele Miraglia del Giudice, Anna Grandone

Front Endocrinol (Lausanne) 2022; 13: 1033179. Published online 2022 Dec 9. doi: 10.3389/fendo.2022.1033179

PMCID:: PMC9780432

Abstract Article PDF–409K

Select item 93035496.

The pituitary tumour‐transforming gene 1/delta‐like homologue 1 pathway plays a key role in liver fibrogenesis

Meritxell Perramón, Silvia Carvajal, Vedrana Reichenbach, Guillermo Fernández‐Varo, Loreto Boix, Laura Macias‐Muñoz, Pedro Melgar‐Lesmes, Jordi Bruix, Shlomo Melmed, Santiago Lamas, Wladimiro Jiménez

Liver Int. 2022 Mar; 42(3): 651–662. Published online 2022 Jan 30. doi: 10.1111/liv.15165

PMCID:: PMC9303549

Abstract Article PDF–1.5M

Select item 89944897.

The adapter SASH1 acts through NOTCH1 and its inhibitor DLK1 in a 3D model of lumenogenesis involving CEACAM1

Kandis Stubblefield, Jennifer Chean, Tung Nguyen, Charng-jui Chen, John E. Shively

Exp Cell Res. Author manuscript; available in PMC 2022 Apr 9.

Published in final edited form as: Exp Cell Res. 2017 Oct 15; 359(2): 384–393. Published online 2017 Aug 18. doi: 10.1016/j.yexcr.2017.08.022

PMCID:: PMC8994489

Abstract Article PDF–3.2M

Select item 89197108.

Low Maternal DLK1 Levels at 26 Weeks Is Associated With Small for Gestational Age at Birth

Aurelie Pham, Delphine Mitanchez, Anne Forhan, Laurence Perin, Yves Le Bouc, Frederic Brioude, Marie-Laure Sobrier, Barbara Heude, Irene Netchine

Front Endocrinol (Lausanne) 2022; 13: 836731. Published online 2022 Feb 28. doi: 10.3389/fendo.2022.836731

PMCID:: PMC8919710

Abstract Article PDF–1.1M

Select item 88090499.

CpG site hypomethylation at ETS1-binding region regulates DLK1 expression in Chinese patients with Tetralogy of Fallot

Guixiang Tian, Lili He, Ruoyi Gu, Jingwei Sun, Weicheng Chen, Yanyan Qian, Xiaojing Ma, Weili Yan, Zhenshan Zhao, Ziqing Xu, Meijiao Suo, Wei Sheng, Guoying Huang

Mol Med Rep. 2022 Mar; 25(3): 93. Published online 2022 Jan 20. doi: 10.3892/mmr.2022.12609

PMCID:: PMC8809049

Abstract Article PDF–2.1M

Select item 872154310.

Emerging Roles of DLK1 in the Stem Cell Niche and Cancer Stemness

Elisa Stellaria Grassi, Alexander Pietras

J Histochem Cytochem. 2022 Jan; 70(1): 17–28. Published online 2021 Oct 4. doi: 10.1369/00221554211048951

PMCID:: PMC8721543

Abstract Article PDF–2.0M

Select item 842405511.

Pregnancy Serum DLK1 Concentrations Are Associated With Indices of Insulin Resistance and Secretion

Clive J Petry, Keith A Burling, Peter Barker, Ieuan A Hughes, Ken K Ong, David B Dunger

J Clin Endocrinol Metab. 2021 Jun; 106(6): e2413–e2422. Published online 2021 Feb 26. doi: 10.1210/clinem/dgab123

PMCID:: PMC8424055

Abstract Article

Select item 829871612.

Human placental piwi-interacting RNA transcriptome is characterized by expression from the DLK1-DIO3 imprinted region

Victor D. Martinez, Adam P. Sage, Brenda C. Minatel, Erin A. Marshall, E. Magda Price, Daiana D. Becker-Santos, Wendy P. Robinson, Wan L. Lam

Sci Rep. 2021; 11: 14981. Published online 2021 Jul 22. doi: 10.1038/s41598-021-93885-3

PMCID:: PMC8298716

Abstract Article PDF–1.4M

Select item 825921013.

Hypoxia-induced preadipocyte factor 1 expression in human lung fibroblasts through ERK/PEA3/c-Jun pathway

Wun-Hao Cheng, Chia-Ling Chen, Jing-Yun Chen, Chien-Huang Lin, Bing-Chang Chen

Mol Med. 2021; 27: 69. Published online 2021 Jul 6. doi: 10.1186/s10020-021-00336-w

PMCID:: PMC8259210

Abstract Article PDF–6.6M

Select item 816503014.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 813458615.

Human delta like 1-expressing human mesenchymal stromal cells promote human T cell development and antigen-specific response in humanized NOD/SCID/IL-2R equation M2

^null (NSG) mice

Do Hee Kwon, Jae Berm Park, Joo Sang Lee, Sung Joo Kim, Bongkum Choi, Ki-Young Lee

Sci Rep. 2021; 11: 10603. Published online 2021 May 19. doi: 10.1038/s41598-021-90110-z

PMCID:: PMC8134586

Abstract Article PDF–6.8M

Select item 796114416.

Bone marrow stromal cells from MDS and AML patients show increased adipogenic potential with reduced Delta-like-1 expression

Marie-Theresa Weickert, Judith S. Hecker, Michèle C. Buck, Christina Schreck, Jennifer Rivière, Matthias Schiemann, Katharina Schallmoser, Florian Bassermann, Dirk Strunk, Robert A. J. Oostendorp, Katharina S. Götze

Sci Rep. 2021; 11: 5944. Published online 2021 Mar 15. doi: 10.1038/s41598-021-85122-8

PMCID:: PMC7961144

Abstract Article PDF–4.6M

Select item 783505817.

Functional characterization of DLK1/MEG3 locus on chromosome 14q32.2 reveals the differentiation of pituitary neuroendocrine tumors

Yiyuan Chen, Hua Gao, Qian Liu, Weiyan Xie, Bin Li, Sen Cheng, Jing Guo, Qiuyue Fang, Haibo Zhu, Zhuang Wang, Jichao Wang, Chuzhong Li, Yazhuo Zhang

Aging (Albany NY) 2021 Jan 15; 13(1): 1422–1439. Published online 2020 Dec 29. doi: 10.18632/aging.202376

PMCID:: PMC7835058

Abstract Article PDF–4.1M

Select item 781383418.

Dll1⁺ quiescent tumor stem cells drive chemoresistance in breast cancer through NF-κB survival pathway

Sushil Kumar, Ajeya Nandi, Snahlata Singh, Rohan Regulapati, Ning Li, John W. Tobias, Christian W. Siebel, Mario Andres Blanco, Andres J. Klein-Szanto, Christopher Lengner, Alana L. Welm, Yibin Kang, Rumela Chakrabarti

Nat Commun. 2021; 12: 432. Published online 2021 Jan 18. doi: 10.1038/s41467-020-20664-5

Correction in:: Nat Commun. 2022; 13: 3927.

PMCID:: PMC7813834

Abstract Article PDF–11M

Select item 775805019.

In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators

Jennifer L. Franks, Raquel C. Martinez-Chacin, Xianxi Wang, Rochelle L. Tiedemann, Thomas Bonacci, Rajarshi Choudhury, Derek L. Bolhuis, Taylor P. Enrico, Ryan D. Mouery, Jeffrey S. Damrauer, Feng Yan, Joseph S. Harrison, M. Ben Major, Katherine A. Hoadley, Aussie Suzuki, Scott B. Rothbart, Nicholas G. Brown, Michael J. Emanuele

PLoS Biol. 2020 Dec; 18(12): e3000975. Published online 2020 Dec 11. doi: 10.1371/journal.pbio.3000975

PMCID:: PMC7758050

Abstract Article PDF–4.2M

Select item 744986220.

Delta-like Factor 1 as a Possible Therapeutic Target for Sarcomas

Han-Soo Kim, Sun Hee Ahn, Ha Jeong Kim, Jong Woong Park, Ilkyu Han

Clin Orthop Surg. 2020 Sep; 12(3): 404–412. Published online 2020 Jun 26. doi: 10.4055/cios19117

PMCID:: PMC7449862

Abstract Article PDF–1.5M

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