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Items: 1 to 20 of 562

1.
IGF1R signaling induces epithelial-mesenchymal plasticity via ITGAV in cutaneous carcinoma
Marta Lopez-Cerda, Laura Lorenzo-Sanz, Victoria da Silva-Diz, Sandra Llop, Rosa M. Penin, Josep Oriol Bermejo, Richard de Goeij-de Haas, Sander R. Piersma, Thang V. Pham, Connie R. Jimenez, Juan Martin-Liberal, Purificación Muñoz
J Exp Clin Cancer Res. 2024; 43: 211. Published online 2024 Jul 29. doi: 10.1186/s13046-024-03119-3
PMCID:
PMC11285232
AbstractArticlePDF–18M
2.
Alternative tyrosine phosphorylation of signaling kinases according to hormone receptor status in breast cancer overexpressing the insulin‐like growth factor receptor type 1
Shigeto Ueda, Hitoshi Tsuda, Kazuhiko Sato, Hideki Takeuchi, Takashi Shigekawa, Osamu Matsubara, Hoshio Hiraide, Hidetaka Mochizuki
Cancer Sci. 2006 Jul; 97(7): 597–604. Published online 2006 May 15. doi: 10.1111/j.1349-7006.2006.00228.x
PMCID:
PMC11158992
AbstractArticlePDF–197K
3.
Potential role of IGF-1R in the interaction between orbital fibroblasts and B lymphocytes: an implication for B lymphocyte depletion in the active inflammatory phase of thyroid-associated ophthalmopathy
Renyan Wang, Delu Song, Yong Zhong, Hui Li
BMC Immunol. 2024; 25: 31. Published online 2024 May 11. doi: 10.1186/s12865-024-00613-3
PMCID:
PMC11088061
AbstractArticlePDF–1.7M
4.
GWAS-identified hyperuricemia-associated IGF1R variant rs6598541 has a limited role in urate mediated inflammation in human mononuclear cells
Orsolya I. Gaal, Ruiqi Liu, Dragoș Marginean, Medeea Badii, Georgiana Cabău, Ioana Hotea, Valentin Nica, Doina Colcear, HINT Consortium, Cristina Pamfil, Tony R. Merriman, Simona Rednic, Radu A. Popp, Tania O. Crișan, Leo A. B. Joosten
Sci Rep. 2024; 14: 3565. Published online 2024 Feb 12. doi: 10.1038/s41598-024-53209-7
PMCID:
PMC10861580
AbstractArticlePDF–1.6M
5.
The HIFIA/LINC02913/IGF1R axis promotes the cell function of adipose-derived mesenchymal stem cells under hypoxia via activating the PI3K/AKT pathway
Xiang Xiong, Liqin Yuan, Kai Yang, Xiancheng Wang
J Transl Med. 2023; 21: 732. Published online 2023 Oct 17. doi: 10.1186/s12967-023-04581-x
PMCID:
PMC10583486
AbstractArticlePDF–9.6M
6.
The Insulin Receptor and Insulin like Growth Factor Receptor 5’ UTRs Support Translation Initiation Independently of EIF4G1
Nicholas K. Clark, Meghan T. Harris, William B. Dahl, Zachary Knotts, Michael T. Marr, II
Mol Cell Biol. 2023; 43(10): 485–499. Published online 2023 Sep 19. doi: 10.1080/10985549.2023.2255120
PMCID:
PMC10569357
AbstractArticlePDF–1.6M
7.
IGF1R-phosphorylated PYCR1 facilitates ELK4 transcriptional activity and sustains tumor growth under hypoxia
Ke Zheng, Nannan Sha, Guofang Hou, Zhuyun Leng, Qin Zhao, Li Zhang, Lingnan He, Meidong Xu, Yuhui Jiang, Tao Chen
Nat Commun. 2023; 14: 6117. Published online 2023 Sep 30. doi: 10.1038/s41467-023-41658-z
PMCID:
PMC10542766
AbstractArticlePDF–2.1M
8.
Obese Asthma Phenotype Is Associated with hsa-miR-26a-1-3p and hsa-miR-376a-3p Modulating the IGF Axis
Marta Gil-Martínez, Clara Lorente-Sorolla, José M. Rodrigo-Muñoz, Sara Naharro, Zahara García-de Castro, Joaquín Sastre, Marcela Valverde-Monge, Santiago Quirce, María L. Caballero, José M. Olaguibel, Victoria del Pozo
Int J Mol Sci. 2023 Jul; 24(14): 11620. Published online 2023 Jul 18. doi: 10.3390/ijms241411620
PMCID:
PMC10380435
AbstractArticlePDF–1.3M
9.
IGF/IGF-1R signal pathway in pain: a promising therapeutic target
Lulin Ma, Wenjing Zhao, Shiqian Huang, Feng Xu, Yafeng Wang, Daling Deng, Tianhao Zhang, Shaofang Shu, Xiangdong Chen
Int J Biol Sci. 2023; 19(11): 3472–3482. Published online 2023 Jul 3. doi: 10.7150/ijbs.84353
PMCID:
PMC10367553
AbstractArticlePDF–1.1M
10.
EHD1-dependent traffic of IGF-1 receptor to the cell surface is essential for Ewing sarcoma tumorigenesis and metastasis
Sukanya Chakraborty, Aaqib M. Bhat, Insha Mushtaq, Haitao Luan, Achyuth Kalluchi, Sameer Mirza, Matthew D. Storck, Nagendra Chaturvedi, Jose Antonio Lopez-Guerrero, Antonio Llombart-Bosch, Isidro Machado, Katia Scotlandi, Jane L. Meza, Gargi Ghosal, Donald W. Coulter, M. Jordan Rowley, Vimla Band, Bhopal C. Mohapatra, Hamid Band
Commun Biol. 2023; 6: 758. Published online 2023 Jul 20. doi: 10.1038/s42003-023-05125-1
PMCID:
PMC10359273
AbstractArticlePDF–9.8M
11.
miR-15b Inhibits the Progression of Glioblastoma Cells Through Targeting Insulin-like Growth Factor Receptor 1
Jian Wang, Huaqiang Liu, Lin Tian, Fachen Wang, Liangbo Han, Wei Zhang, Yun-an Bai
Horm Cancer. 2017 Feb; 8(1): 49–57. Published online 2016 Nov 28. doi: 10.1007/s12672-016-0276-z
PMCID:
PMC10355966
AbstractArticlePDF–1.6M
12.
Type 1 IGF Receptor Localization in Paediatric Gliomas: Significant Association with WHO Grading and Clinical Outcome
Florencia Clément, Ayelen Martin, Marcela Venara, Maria de Luján Calcagno, Cecilia Mathó, Silvana Maglio, Mercedes García Lombardi, Ignacio Bergadá, Patricia A Pennisi
Horm Cancer. 2018 Jun; 9(3): 205–214. Published online 2018 Mar 9. doi: 10.1007/s12672-018-0328-7
PMCID:
PMC10355889
AbstractArticlePDF–819K
13.
Downregulation of IGF1R Expression Inhibits Growth and Enhances Cisplatin Sensitivity of Head and Neck Squamous Cell Carcinoma Cells In Vitro
Ashraf Khalil, Mark J. Jameson
Horm Cancer. 2019 Feb; 10(1): 11–23. Published online 2018 Oct 23. doi: 10.1007/s12672-018-0352-7
PMCID:
PMC10355712
AbstractArticlePDF–1.5M
14.
A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2–Bispecific Antibody for Combination Cancer Therapy
Amr El Zawily, Frederick S. Vizeacoumar, Renuka Dahiya, Sara L. Banerjee, Kalpana K. Bhanumathy, Hussain Elhasasna, Glinton Hanover, Jessica C. Sharpe, Malkon G. Sanchez, Paul Greidanus, R. Greg Stacey, Kyung-Mee Moon, Ilya Alexandrov, Juha P. Himanen, Dimitar B. Nikolov, Humphrey Fonge, Aaron P. White, Leonard J. Foster, Bingcheng Wang, Behzad M. Toosi, Nicolas Bisson, Tajib A. Mirzabekov, Franco J. Vizeacoumar, Andrew Freywald
Clin Cancer Res. 2023 Jul 14; 29(14): 2686–2701. Published online 2023 Mar 28. doi: 10.1158/1078-0432.CCR-22-2535
PMCID:
PMC10345963
AbstractArticlePDF–13M
15.
Circ_0005615 restrains the progression of multiple myeloma through modulating miR-331-3p and IGF1R regulatory cascade
Qinxin Zhang, Hui Duan, Wupeng Yang, Hao Liu, Xiaoyang Tao, Yan Zhang
J Orthop Surg Res. 2023; 18: 356. Published online 2023 May 12. doi: 10.1186/s13018-023-03832-3
PMCID:
PMC10176712
AbstractArticlePDF–5.3M
16.
The interplay between IGF-1R signaling and Hippo-YAP in breast cancer stem cells
Yu-Tzu Chan, Ruey-Jen Lin, Ya-Hui Wang, Tsai-Hsien Hung, Yenlin Huang, John Yu, Jyh-Cherng Yu, Alice L. Yu
Cell Commun Signal. 2023; 21: 81. Published online 2023 Apr 20. doi: 10.1186/s12964-023-01088-2
PMCID:
PMC10120239
AbstractArticlePDF–3.7M
17.
The role of RNF149 in the pre-emptive quality control substrate ubiquitination
Aster Legesse, Nathali Kaushansky, Ilana Braunstein, Haddas Saad, Gerardo Lederkremer, Ami Navon, Ariel Stanhill
Commun Biol. 2023; 6: 385. Published online 2023 Apr 8. doi: 10.1038/s42003-023-04763-9
PMCID:
PMC10082771
AbstractArticlePDF–2.2M
18.
Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong
Mol Cell. Author manuscript; available in PMC 2023 Apr 4.
Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015
PMCID:
PMC10072906
AbstractArticlePDF–4.2M
19.
Leucine-973 is a crucial residue differentiating insulin and IGF-1 receptor signaling
Hirofumi Nagao, Weikang Cai, Bruna B. Brandão, Nicolai J. Wewer Albrechtsen, Martin Steger, Arijeet K. Gattu, Hui Pan, Jonathan M. Dreyfuss, F. Thomas Wunderlich, Matthias Mann, C. Ronald Kahn
J Clin Invest. 2023 Feb 15; 133(4): e161472. Published online 2023 Feb 15. doi: 10.1172/JCI161472
PMCID:
PMC9927934
AbstractArticlePDF–2.8M
20.
FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia
Xiao-Na Zhu, Yu-Sheng Wei, Qian Yang, Hao-Ran Liu, Zhe Zhi, Di Zhu, Li Xia, Deng-Li Hong, Yun Yu, Guo-Qiang Chen
J Hematol Oncol. 2023; 16: 9. Published online 2023 Feb 11. doi: 10.1186/s13045-023-01400-0
PMCID:
PMC9922468
AbstractArticlePDF–4.9M

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