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Select item 104424181.

Vacuolar-ATPase-mediated muscle acidification caused muscular mechanical nociceptive hypersensitivity after chronic stress in rats, which involved extracellular matrix proteoglycan and ASIC3

Teruaki Nasu, Amane Hori, Norio Hotta, Chiaki Kihara, Asako Kubo, Kimiaki Katanosaka, Masamitsu Suzuki, Kazue Mizumura

Sci Rep. 2023; 13: 13585. Published online 2023 Aug 21. doi: 10.1038/s41598-023-39633-1

PMCID:: PMC10442418

Abstract Article PDF–1.3M

Select item 87159812.

Upregulation of acid sensing ion channels is associated with esophageal hypersensitivity in GERD

Xu Han, Yawen Zhang, Allen Lee, Zhaoshen Li, Jun Gao, Xiaoyin Wu, Jiulong Zhao, Hui Wang, Di Chen, Duowu Zou, Chung Owyang

FASEB J. 2022 Jan; 36(1): e22083. Published online 2021 Dec 17. doi: 10.1096/fj.202100606R

PMCID:: PMC8715981

Abstract Article PDF–1.6M

Select item 81784203.

Retrograde nerve growth factor signaling modulates tooth mechanical hyperalgesia induced by orthodontic tooth movement via acid-sensing ion channel 3

Meiya Gao, Xinyu Yan, Yanzhu Lu, Linghuan Ren, Shizhen Zhang, Xiaoqi Zhang, Qianyun Kuang, Lu Liu, Jing Zhou, Yan Wang, Wenli Lai, Hu Long

Int J Oral Sci. 2021; 13: 18. Published online 2021 Jun 4. doi: 10.1038/s41368-021-00124-6

PMCID:: PMC8178420

Abstract Article PDF–12M

Select item 77244024.

ASIC3 inhibition modulates inflammation-induced changes in the activity and sensitivity of Aδ and C fiber sensory neurons that innervate bone

Michael Morgan, Jenny Thai, Phu Trinh, Mohamed Habib, Kelly N Effendi, Jason J Ivanusic

Mol Pain. 2020; 16: 1744806920975950. Published online 2020 Dec 6. doi: 10.1177/1744806920975950

PMCID:: PMC7724402

Abstract Article PDF–1.5M

Select item 75650925.

Histidine Residues Are Responsible for Bidirectional Effects of Zinc on Acid-Sensing Ion Channel 1a/3 Heteromeric Channels

Qian Jiang, Andrew M. Peterson, Yuyang Chu, Xiaolan Yao, Xiang-ming Zha, Xiang-Ping Chu

Biomolecules. 2020 Sep; 10(9): 1264. Published online 2020 Sep 2. doi: 10.3390/biom10091264

PMCID:: PMC7565092

Abstract Article PDF–6.0M

Select item 73465386.

Functional knockout of ASIC3 attenuates the exercise pressor reflex in decerebrated rats with ligated femoral arteries

Joyce S. Kim, Guillaume P. Ducrocq, Marc P. Kaufman

Am J Physiol Heart Circ Physiol. 2020 May 1; 318(5): H1316–H1324. Published online 2020 Apr 17. doi: 10.1152/ajpheart.00137.2020

PMCID:: PMC7346538

Abstract Article

Select item 70548577.

Insights into the molecular mechanisms underlying the inhibition of acid-sensing ion channel 3 gating by stomatin

Robert C. Klipp, Megan M. Cullinan, John R. Bankston

J Gen Physiol. 2020 Mar 2; 152(3): e201912471. Published online 2020 Feb 3. doi: 10.1085/jgp.201912471

PMCID:: PMC7054857

Abstract Article PDF–3.5M

Select item 68798478.

Effect of knockout of the ASIC3 on cardiovascular reflexes arising from hindlimb muscle in decerebrated rats

Joyce S. Kim, Jonathan E. Harms, Victor Ruiz-Velasco, Marc P. Kaufman

Am J Physiol Regul Integr Comp Physiol. 2019 Nov 1; 317(5): R641–R648. Published online 2019 Jul 26. doi: 10.1152/ajpregu.00148.2019

PMCID:: PMC6879847

Abstract Article

Select item 67638769.

Nonsteroid Anti-Inflammatory Drugs Inhibit Both the Activity and the Inflammation-Induced Expression of Acid-Sensing Ion Channels in Nociceptors

Nicolas Voilley, Jan de Weille, Julien Mamet, Michel Lazdunski

J Neurosci. 2001 Oct 15; 21(20): 8026–8033. doi: 10.1523/JNEUROSCI.21-20-08026.2001

PMCID:: PMC6763876

Abstract Article PDF–726K

Select item 675846010.

ProInflammatory Mediators, Stimulators of Sensory Neuron Excitability via the Expression of Acid-Sensing Ion Channels

Julien Mamet, Anne Baron, Michel Lazdunski, Nicolas Voilley

J Neurosci. 2002 Dec 15; 22(24): 10662–10670. doi: 10.1523/JNEUROSCI.22-24-10662.2002

PMCID:: PMC6758460

Abstract Article PDF–299K

Select item 663295911.

Acid-Sensing Ion Channels in Postoperative Pain

Emmanuel Deval, Jacques Noël, Xavier Gasull, Anne Delaunay, Abdelkrim Alloui, Valérie Friend, Alain Eschalier, Michel Lazdunski, Eric Lingueglia

J Neurosci. 2011 Apr 20; 31(16): 6059–6066. doi: 10.1523/JNEUROSCI.5266-10.2011

PMCID:: PMC6632959

Abstract Article PDF–821K

Select item 597017312.

Identification of a unique Ca²⁺-binding site in rat acid-sensing ion channel 3

Zhicheng Zuo, Rachel N. Smith, Zhenglan Chen, Amruta S. Agharkar, Heather D. Snell, Renqi Huang, Jin Liu, Eric B. Gonzales

Nat Commun. 2018; 9: 2082. Published online 2018 May 25. doi: 10.1038/s41467-018-04424-0

PMCID:: PMC5970173

Abstract Article PDF–2.9M

Select item 589360413.

The ASIC3/P2X3 cognate receptor is a pain-relevant and ligand-gated cationic channel

Gabriele Stephan, Lumei Huang, Yong Tang, Sandra Vilotti, Elsa Fabbretti, Ye Yu, Wolfgang Nörenberg, Heike Franke, Flóra Gölöncsér, Beáta Sperlágh, Anke Dopychai, Ralf Hausmann, Günther Schmalzing, Patrizia Rubini, Peter Illes

Nat Commun. 2018; 9: 1354. Published online 2018 Apr 10. doi: 10.1038/s41467-018-03728-5

Correction in:: Nat Commun. 2018; 9: 3351.

PMCID:: PMC5893604

Abstract Article PDF–3.2M

Select item 471355614.

Amiloride suppresses pilocarpine-induced seizures via ASICs other than NHE in rats

Jing-Jing Liang, Li-Fang Huang, Xu-Ming Chen, Song-Qing Pan, Zu-Neng Lu, Zhe-Man Xiao

Int J Clin Exp Pathol. 2015; 8(11): 14507–14513. Published online 2015 Nov 1.

PMCID:: PMC4713556

Abstract Article PDF–533K

Select item 447243315.

ASIC2a and ASIC3 heteromultimerize to form pH-sensitive channels in mouse cardiac DRG neurons

Tomonori Hattori, Jie Chen, Anne Marie S. Harding, Margaret P. Price, Yongjun Lu, Francois M. Abboud, Christopher J. Benson

Circ Res. Author manuscript; available in PMC 2015 Jun 18.

Published in final edited form as: Circ Res. 2009 Jul 31; 105(3): 279–286. Published online 2009 Jul 9. doi: 10.1161/CIRCRESAHA.109.202036

PMCID:: PMC4472433

Abstract Article PDF–1.7M

Select item 377305316.

pH-evoked dural afferent signaling is mediated by ASIC3 and is sensitized by mast cell mediators

Jin Yan, Xiaomei Wei, Christina Bischoff, Rebecca M. Edelmayer, Gregory Dussor

Headache. Author manuscript; available in PMC 2014 Sep 1.

Published in final edited form as: Headache. 2013 Sep; 53(8): 1250–1261. Published online 2013 Jun 28. doi: 10.1111/head.12152

PMCID:: PMC3773053

Abstract Article PDF–1.5M

Select item 354357317.

Acid-sensing ion channels (ASICs) are differentially modulated by anions dependent on their subunit composition

Nobuyoshi Kusama, Mamta Gautam, Anne Marie S. Harding, Peter M. Snyder, Christopher J. Benson

Am J Physiol Cell Physiol. 2013 Jan 1; 304(1): C89–C101. Published online 2012 Nov 7. doi: 10.1152/ajpcell.00216.2012

PMCID:: PMC3543573

Abstract Article

Select item 343378618.

A stomatin dimer modulates the activity of acid-sensing ion channels

Janko Brand, Ewan St J Smith, David Schwefel, Liudmila Lapatsina, Kate Poole, Damir Omerbašić, Alexey Kozlenkov, Joachim Behlke, Gary R Lewin, Oliver Daumke

EMBO J. 2012 Aug 29; 31(17): 3635–3646. Published online 2012 Jul 31. doi: 10.1038/emboj.2012.203