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Select item 113160681.

Fibroblast growth receptor 1 is regulated by G-quadruplex in metastatic breast cancer

Hang Lin, Muhammad Hassan Safdar, Sarah Washburn, Saeed S. Akhand, Jonathan Dickerhoff, Mitchell Ayers, Marvis Monteiro, Luis Solorio, Danzhou Yang, Michael K. Wendt

Commun Biol. 2024; 7: 963. Published online 2024 Aug 9. doi: 10.1038/s42003-024-06602-x

PMCID:: PMC11316068

Abstract Article PDF–6.3M

Select item 113082982.

Genome-wide open reading frame profiling identifies fibroblast growth factor signaling as a driver of PD-L1 expression in head and neck squamous cell carcinoma

Jacqueline E Mann, Joshua D. Smith, Aditi Kulkarni, Susan K. Foltin, Erin B. Scheftz, Isabel R. Murray, Elizabeth Genterblum-Miller, Collin V. Brummel, Apurva Bhangale, Rebecca C. Holesli, J. Chad Brenner

Oral Oncol. Author manuscript; available in PMC 2024 Aug 8.

Published in final edited form as: Oral Oncol. 2023 Nov; 146: 106562. Published online 2023 Sep 2. doi: 10.1016/j.oraloncology.2023.106562

PMCID:: PMC11308298

Abstract Article PDF–2.1M

Select item 112879993.

Identification of mechanism of the oncogenic role of FGFR1 in papillary thyroid carcinoma

Xiong Bing Li, Jia Li Li, Chao Wang, Yong Zhang, Jing Li

Eur J Histochem. 2024 Jun 27; 68(3): 4048. Published online 2024 Jul 22. doi: 10.4081/ejh.2024.4048

PMCID:: PMC11287999

Abstract Article PDF–830K

Select item 112802134.

Clinical manifestations and spermatogenesis outcomes in Chinese patients with congenital hypogonadotropic hypogonadism caused by inherited or de novo FGFR1 mutations

Yu-Fan Yang, Hai-Lu Ma, Xi Wang, Min Nie, Jiang-Feng Mao, Xue-Yan Wu

Asian J Androl. 2024 Jul-Aug; 26(4): 426–432. Published online 2024 Jan 9. doi: 10.4103/aja202366

PMCID:: PMC11280213

Abstract Article PDF–843K

Select item 110732485.

FGF primes angioblast formation by inducing ETV2 and LMO2 via FGFR1/BRAF/MEK/ERK

Peng-Chieh Chen, Ya-Wen Hsueh, Yi-Hsuan Lee, Hung-Wen Tsai, Kuen-Jer Tsai, Po-Min Chiang

Cell Mol Life Sci. 2021 Mar; 78(5): 2199–2212. Published online 2020 Sep 10. doi: 10.1007/s00018-020-03630-8

PMCID:: PMC11073248

Abstract Article PDF–3.1M

Select item 110397276.

RAPID resistance to BET inhibitors is mediated by FGFR1 in glioblastoma

Anna M. Jermakowicz, Alison M. Kurimchak, Katherine J. Johnson, Florence Bourgain-Guglielmetti, Simon Kaeppeli, Maurizio Affer, Hari Pradhyumnan, Robert K. Suter, Winston Walters, Maria Cepero, James S. Duncan, Nagi G. Ayad

Sci Rep. 2024; 14: 9284. Published online 2024 Apr 23. doi: 10.1038/s41598-024-60031-8

PMCID:: PMC11039727

Abstract Article PDF–5.5M

Select item 109773537.

How human genetic context can inform pathogenicity classification: FGFR1 variation in idiopathic hypogonadotropic hypogonadism

Wanxue Xu, Lacey Plummer, Stephanie B. Seminara, Ravikumar Balasubramanian, Margaret F. Lippincott

Hum Genet. Author manuscript; available in PMC 2024 Mar 28.

Published in final edited form as: Hum Genet. 2023 Nov; 142(11): 1611–1619. Published online 2023 Oct 7. doi: 10.1007/s00439-023-02601-w

PMCID:: PMC10977353

Abstract Article PDF–661K

Select item 108827698.

Clinicopathological analysis of rosette-forming glioneuronal tumors

Jing Liu, Fan Lin, Yanhua Sun, Xia Liu

Diagn Pathol. 2024; 19: 39. Published online 2024 Feb 22. doi: 10.1186/s13000-024-01465-6

PMCID:: PMC10882769

Abstract Article PDF–6.6M

Select item 108405089.

Spatial distribution and functional relevance of FGFR1 and FGFR2 expression for glioblastoma tumor invasion

Nawal Alshahrany, Ayesha Begum, Dorit Siebzehnrubl, Ana Jimenez-Pascual, Florian A. Siebzehnrubl

Cancer Lett. 2023 Sep 1; 571: 216349. doi: 10.1016/j.canlet.2023.216349

PMCID:: PMC10840508

Abstract Article

Select item 1082648010.

Additional mutation in PROKR2 and phenotypic differences in a Kallmann syndrome/normosmic congenital hypogonadotropic hypogonadism family carrying FGFR1 missense mutation

Kentaro Ichioka, Takeshi Yoshikawa, Hiroko Kimura, Ryoichi Saito

BMJ Case Rep. 2024; 17(1): e258042. Published online 2024 Jan 25. doi: 10.1136/bcr-2023-258042

PMCID:: PMC10826480

Abstract Article PDF–1.7M

Select item 1068679511.

NF-κB downstream miR-1262 disturbs colon cancer cell malignant behaviors by targeting FGFR1: NF-κB/miR-1262/FGFR1 modulates colon cancer oncogenesis

Weilin Zhang, Zhongcheng Huang, Zhigang Xiao, Hui Wang, Qianchao Liao, Zhengru Deng, Deqing Wu, Junjiang Wang, Yong Li

Acta Biochim Biophys Sin (Shanghai) 2023 Nov 25; 55(11): 1819–1832. Published online 2023 Oct 20. doi: 10.3724/abbs.2023235

PMCID:: PMC10686795

Abstract Article PDF–3.5M

Select item 1061776712.

Somatic rearrangements causing oncogenic ectodomain deletions of FGFR1 in squamous cell lung cancer

Florian Malchers, Lucia Nogova, Martijn H.A. van Attekum, Lukas Maas, Johannes Brägelmann, Christoph Bartenhagen, Luc Girard, Graziella Bosco, Ilona Dahmen, Sebastian Michels, Clare E. Weeden, Andreas H. Scheel, Lydia Meder, Kristina Golfmann, Philipp Schuldt, Janna Siemanowski, Jan Rehker, Sabine Merkelbach-Bruse, Roopika Menon, Oliver Gautschi, Johannes M. Heuckmann, Elisabeth Brambilla, Marie-Liesse Asselin-Labat, Thorsten Persigehl, John D. Minna, Henning Walczak, Roland T. Ullrich, Matthias Fischer, Hans Christian Reinhardt, Jürgen Wolf, Reinhard Büttner, Martin Peifer, Julie George, Roman K. Thomas

J Clin Invest. 2023 Nov 1; 133(21): e170217. Published online 2023 Nov 1. doi: 10.1172/JCI170217

PMCID:: PMC10617767

Abstract Article PDF–8.7M

Select item 1057634313.

FGFR1 variants contributed to families with tooth agenesis

Siyue Yao, Xi Zhou, Min Gu, Chengcheng Zhang, Oliver Bartsch, Barbara Vona, Liwen Fan, Lan Ma, Yongchu Pan

Hum Genomics. 2023; 17: 93. Published online 2023 Oct 13. doi: 10.1186/s40246-023-00539-8

PMCID:: PMC10576343

Abstract Article PDF–4.5M

Select item 1053917014.

Exploiting the fibroblast growth factor receptor-1 vulnerability to therapeutically restrict the MYC-EZH2-CDKN1C axis-driven proliferation in Mantle cell lymphoma

Anuvrat Sircar, Satishkumar Singh, Zijun Y. Xu-Monette, Krysta Mila Coyle, Laura K. Hilton, Evangelia Chavdoula, Parvathi Ranganathan, Neeraj Jain, Walter Hanel, Philip Tsichlis, Lapo Alinari, Blake R. Peterson, Jianguo Tao, Natarajan Muthusamy, Robert Baiocchi, Narendranath Epperla, Ken H. Young, Ryan Morin, Lalit Sehgal

Leukemia. 2023; 37(10): 2094–2106. Published online 2023 Aug 19. doi: 10.1038/s41375-023-02006-8

PMCID:: PMC10539170

Abstract Article PDF–5.3M

Select item 1007290615.

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity

Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong

Mol Cell. Author manuscript; available in PMC 2023 Apr 4.

Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015

PMCID:: PMC10072906

Abstract Article PDF–4.2M

Select item 1003675416.

Deficiency of endothelial FGFR1 signaling via upregulation of ROCK2 activity aggravated ALI/ARDS

Yue Deng, Xingming Huang, Yan Hu, Weiting Zhong, Hua Zhang, Chunheng Mo, Hongjun Wang, Bi-Sen Ding, Chen Wang

Front Immunol. 2023; 14: 1041533. Published online 2023 Mar 10. doi: 10.3389/fimmu.2023.1041533

PMCID:: PMC10036754

Abstract Article PDF–27M

Select item 997643017.

Mutation spectrum of Kallmann syndrome: identification of five novel mutations across ANOS1 and FGFR1

Guoming Chu, Pingping Li, Qian Zhao, Rong He, Yanyan Zhao

Reprod Biol Endocrinol. 2023; 21: 23. Published online 2023 Mar 1. doi: 10.1186/s12958-023-01074-w

PMCID:: PMC9976430

Abstract Article PDF–4.2M

Select item 992219618.

The Interaction of Apelin and FGFR1 Ameliorated the Kidney Fibrosis through Suppression of TGFβ-Induced Endothelial-to-Mesenchymal Transition

Rongfen Gao, Yumin Wu, Qian Yang, Liangdong Chen, Jiwei Chen, Boyong Wang, Zeming Liu, Juan Jin, Jinpeng Li, Gaosong Wu

Oxid Med Cell Longev. 2023; 2023: 5012474. Published online 2023 Feb 4. doi: 10.1155/2023/5012474

PMCID:: PMC9922196

Abstract Article PDF–3.9M

Select item 990999119.

The FGFR1 Signaling Pathway Upregulates the Oncogenic Transcription Factor FOXQ1 to Promote Breast Cancer Cell Growth

Yan Lin, Fengkang Lin, Zhuoran Zhang, Lijia Peng, Wenli Yang, Mao Yang, Bo Luo, Ting Wu, Dabing Li, Xuesen Li, Bing Ran, Songyot Anuchapreeda, Rujirek Chaiwongsa, Pinyaphat Khamphikham, Suwit Duangmano, Jianming Xu, Tao He, Sakorn Pornprasert

Int J Biol Sci. 2023; 19(3): 744–759. Published online 2023 Jan 1. doi: 10.7150/ijbs.74574

PMCID:: PMC9909991

Abstract Article PDF–5.7M

Select item 977945620.

Aberrations in FGFR1, FGFR2, and RIP5 Expression in Human Congenital Anomalies of the Kidney and Urinary Tract (CAKUT)

Nela Kelam, Anita Racetin, Mirjana Polović, Benjamin Benzon, Marin Ogorevc, Katarina Vukojević, Merica Glavina Durdov, Ana Dunatov Huljev, Ivana Kuzmić Prusac, Davor Čarić, Fila Raguž, Sandra Kostić

Int J Mol Sci. 2022 Dec; 23(24): 15537. Published online 2022 Dec 8. doi: 10.3390/ijms232415537

PMCID:: PMC9779456

Abstract Article PDF–4.1M

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