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Select item 101516151.

Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein–protein interactions in the human cell

Tara K. Bartolec, Xabier Vázquez-Campos, Alexander Norman, Clement Luong, Marcus Johnson, Richard J. Payne, Marc R. Wilkins, Joel P. Mackay, Jason K. K. Low

Proc Natl Acad Sci U S A. 2023 Apr 25; 120(17): e2219418120. Published online 2023 Apr 18. doi: 10.1073/pnas.2219418120

PMCID:: PMC10151615

Abstract Article PDF–2.9M

Select item 99459692.

Cryo-EM structure of human voltage-gated sodium channel Na_v1.6

Xiao Fan, Jian Huang, Xueqin Jin, Nieng Yan

Proc Natl Acad Sci U S A. 2023 Jan 31; 120(5): e2220578120. Published online 2023 Jan 25. doi: 10.1073/pnas.2220578120

PMCID:: PMC9945969

Abstract Article PDF–2.5M

Select item 89183593.

Further evidence of affected females with a heterozygous variant in FGF13 causing X-linked developmental and epileptic encephalopathy 90

Dhanya Lakshmi Narayanan, Purvi Majethia, Aroor Shrikiran, Shahyan Siddiqui, Ashwin Dalal, Anju Shukla

Eur J Med Genet. Author manuscript; available in PMC 2023 Jan 1.

Published in final edited form as: Eur J Med Genet. 2022 Jan; 65(1): 104403. Published online 2021 Dec 4. doi: 10.1016/j.ejmg.2021.104403

PMCID:: PMC8918359

Abstract Article PDF–366K

Select item 85866894.

FGF13 enhances resistance to platinum drugs by regulating hCTR1 and ATP7A via a microtubule‐stabilizing effect

Hang Yu, Handong Wang, Anran Qie, Jiaqi Wang, Yueping Liu, Guoqiang Gu, Jing Yang, Hanqiu Zhang, Wensen Pan, Ziqiang Tian, Chuan Wang

Cancer Sci. 2021 Nov; 112(11): 4655–4668. Published online 2021 Sep 28. doi: 10.1111/cas.15137

PMCID:: PMC8586689

Abstract Article PDF–2.6M

Select item 82414425.

5'-UTR SNP of FGF13 causes translational defect and intellectual disability

Xingyu Pan, Jingrong Zhao, Zhiying Zhou, Jijun Chen, Zhenxing Yang, Yuxuan Wu, Meizhu Bai, Yang Jiao, Yun Yang, Xuye Hu, Tianling Cheng, Qianyun Lu, Bin Wang, Chang-Lin Li, Ying-Jin Lu, Lei Diao, Yan-Qing Zhong, Jing Pan, Jianmin Zhu, Hua-Sheng Xiao, Zi-Long Qiu, Jinsong Li, Zefeng Wang, Jingyi Hui, Lan Bao, Xu Zhang

eLife. 2021; 10: e63021. Published online 2021 Jun 29. doi: 10.7554/eLife.63021

PMCID:: PMC8241442

Abstract Article PDF–5.5M

Select item 81650306.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 80844607.

FGF10 and FGF13 genetic variation and tooth-size discrepancies

Guido Artemio Marañón-Vásquez, Alexandre Rezende Vieira, Luiza Vertuan dos Santos, Arthur Silva Cunha, Suyany Gabriely Weiss, Mônica Tirre de Souza Araujo, Ana Maria Bolognese, Rafaela Scariot, Erika Calvano Küchler, Maria Bernadete Sasso Stuani

Angle Orthod. 2021 May; 91(3): 356–362. Published online 2021 Jan 25. doi: 10.2319/060920-531.1

PMCID:: PMC8084460

Abstract Article PDF–71K

Select item 78309398.

lncRNA LINC00963 downregulation regulates colorectal cancer tumorigenesis and progression via the miR-10b/FGF13 axis

Yujin Wu, Longling Cong, Wenjian Chen, Xuechuan Wang, Fanghua Qiu

Mol Med Rep. 2021 Mar; 23(3): 211. Published online 2021 Jan 18. doi: 10.3892/mmr.2021.11850

PMCID:: PMC7830939

Abstract Article PDF–2.4M

Select item 78206239.

Missense variants in the N-terminal domain of the A isoform of FHF2/FGF13 cause an X-linked developmental and epileptic encephalopathy

Andrew E. Fry, Christopher Marra, Anna V. Derrick, William O. Pickrell, Adam T. Higgins, Johann te Water Naude, Martin A. McClatchey, Sally J. Davies, Kay A. Metcalfe, Hui Jeen Tan, Rajiv Mohanraj, Shivaram Avula, Denise Williams, Lauren I. Brady, Ronit Mesterman, Mark A. Tarnopolsky, Yuehua Zhang, Ying Yang, Xiaodong Wang, Genomics England Research Consortium, Mark I. Rees, Mitchell Goldfarb, Seo-Kyung Chung

Am J Hum Genet. 2021 Jan 7; 108(1): 176–185. Published online 2020 Nov 26. doi: 10.1016/j.ajhg.2020.10.017

PMCID:: PMC7820623

Abstract Article PDF–1.2M

Select item 767894610.

FGF13 interaction with SHCBP1 activates AKT-GSK3α/β signaling and promotes the proliferation of A549 cells

Hongzhao Lu, Meichen Yin, Ling Wang, Jia Cheng, Wei Cheng, Huanping An, Tao Zhang

Cancer Biol Ther. 2020; 21(11): 1014–1024. Published online 2020 Oct 16. doi: 10.1080/15384047.2020.1824512

PMCID:: PMC7678946

Abstract Article PDF–7.1M

Select item 716998311.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 692775412.

Genome-wide CRISPR screening reveals genetic modifiers of mutant EGFR dependence in human NSCLC

Hao Zeng, Johnny Castillo-Cabrera, Mika Manser, Bo Lu, Zinger Yang, Vaik Strande, Damien Begue, Raffaella Zamponi, Shumei Qiu, Frederic Sigoillot, Qiong Wang, Alicia Lindeman, John S Reece-Hoyes, Carsten Russ, Debora Bonenfant, Xiaomo Jiang, Youzhen Wang, Feng Cong

eLife. 2019; 8: e50223. Published online 2019 Nov 19. doi: 10.7554/eLife.50223

PMCID:: PMC6927754

Abstract Article PDF–5.1M

Select item 672970613.

Fibroblast Growth Factor Homologous Factor 2B: Association with Na_v1.6 and Selective Colocalization at Nodes of Ranvier of Dorsal Root Axons

Ellen K. Wittmack, Anthony M. Rush, Matthew J. Craner, Mitchell Goldfarb, Stephen G. Waxman, Sulayman D. Dib-Hajj

J Neurosci. 2004 Jul 28; 24(30): 6765–6775. doi: 10.1523/JNEUROSCI.1628-04.2004

PMCID:: PMC6729706

Abstract Article PDF–607K

Select item 615887214.

Intrafollicular fibroblast growth factor 13 in polycystic ovary syndrome: relationship with androgen levels and oocyte developmental competence

Yu Liu, Shengxian Li, Tao Tao, Xiaoxue Li, Qinling Zhu, Yu Liao, Jing Ma, Yun Sun, Wei Liu

J Ovarian Res. 2018; 11: 87. Published online 2018 Sep 26. doi: 10.1186/s13048-018-0455-3

PMCID:: PMC6158872

Abstract Article PDF–666K

Select item 565551915.

C-terminal phosphorylation of Na_V1.5 impairs FGF13-dependent regulation of channel inactivation

Sophie Burel, Fabien C. Coyan, Maxime Lorenzini, Matthew R. Meyer, Cheryl F. Lichti, Joan H. Brown, Gildas Loussouarn, Flavien Charpentier, Jeanne M. Nerbonne, R. Reid Townsend, Lars S. Maier, Céline Marionneau

J Biol Chem. 2017 Oct 20; 292(42): 17431–17448. Published online 2017 Sep 7. doi: 10.1074/jbc.M117.787788

PMCID:: PMC5655519

Abstract Article PDF–4.3M

Select item 549522516.

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing

Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114

PMCID:: PMC5495225

Abstract Article PDF–1.3M

Select item 527848317.

Regulatory module involving FGF13, miR-504, and p53 regulates ribosomal biogenesis and supports cancer cell survival

Débora R. Bublik, Slađana Bursać, Michal Sheffer, Ines Oršolić, Tali Shalit, Ohad Tarcic, Eran Kotler, Odelia Mouhadeb, Yonit Hoffman, Gilad Fuchs, Yishai Levin, Siniša Volarević, Moshe Oren

Proc Natl Acad Sci U S A. 2017 Jan 24; 114(4): E496–E505. Published online 2016 Dec 19. doi: 10.1073/pnas.1614876114

PMCID:: PMC5278483

Abstract Article PDF–1.8M

Select item 526093918.

Gsk3β and Tomm20 are substrates of the SCFFbxo7/PARK15 ubiquitin ligase associated with Parkinson's disease

Felipe Roberti Teixeira, Suzanne J. Randle, Shachi P. Patel, Tycho E.T. Mevissen, Grasilda Zenkeviciute, Tie Koide, David Komander, Heike Laman

Biochem J. 2016 Oct 15; 473(20): 3563–3580. Prepublished online 2016 Aug 8. Published online 2016 Oct 11. doi: 10.1042/BCJ20160387

PMCID:: PMC5260939

Abstract Article PDF–1.1M

Select item 498846219.

FGF13 modulates the gating properties of the cardiac sodium channel Na_v1.5 in an isoform-specific manner

Jing Yang, Zhihua Wang, Daniel S. Sinden, Xiangchong Wang, Bin Shan, Xiao Yu, Hailin Zhang, Geoffrey S. Pitt, Chuan Wang

Channels (Austin) 2016 Sep-Oct; 10(5): 410–420. Published online 2016 May 31. doi: 10.1080/19336950.2016.1190055

PMCID:: PMC4988462

Abstract Article PDF–1.1M

Select item 460350220.

SCN5A variant that blocks fibroblast growth factor homologous factor regulation causes human arrhythmia

Hassan Musa, Crystal F. Kline, Amy C. Sturm, Nathaniel Murphy, Sara Adelman, Chaojian Wang, Haidun Yan, Benjamin L. Johnson, Thomas A. Csepe, Ahmet Kilic, Robert S. D. Higgins, Paul M. L. Janssen, Vadim V. Fedorov, Raul Weiss, Christina Salazar, Thomas J. Hund, Geoffrey S. Pitt, Peter J. Mohler

Proc Natl Acad Sci U S A. 2015 Oct 6; 112(40): 12528–12533. Published online 2015 Sep 21. doi: 10.1073/pnas.1516430112

PMCID:: PMC4603502

Abstract Article PDF–1.4M

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