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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 107903452.

Phosphatases modified by LH signaling in ovarian follicles: testing their role in regulating the NPR2 guanylyl cyclase

Jeremy R Egbert, Ivan Silbern, Tracy F Uliasz, Katie M Lowther, Siu-Pok Yee, Henning Urlaub, Laurinda A Jaffe

Biol Reprod. 2024 Jan; 110(1): 102–115. Published online 2023 Sep 29. doi: 10.1093/biolre/ioad130

PMCID:: PMC10790345

Abstract Article PDF–1.7M

Select item 103713453.

Ablation of C-type natriuretic peptide/cGMP signaling in fibroblasts exacerbates adverse cardiac remodeling in mice

Franziska Werner, Estefania Prentki Santos, Konstanze Michel, Hanna Schrader, Katharina Völker, Tamara Potapenko, Lisa Krebes, Marco Abeßer, Dorothe Möllmann, Martin Schlattjan, Hannes Schmidt, Boris V. Skryabin, Katarina Špiranec Spes, Kai Schuh, Christopher P. Denton, Hideo A. Baba, Michaela Kuhn

JCI Insight. 2023 Jul 10; 8(13): e160416. Published online 2023 Jul 10. doi: 10.1172/jci.insight.160416

PMCID:: PMC10371345

Abstract Article PDF–7.4M

Select item 98125854.

Retinal degeneration protein 3 controls membrane guanylate cyclase activities in brain tissue

Yaoyu Chen, Anja U. Bräuer, Karl-Wilhelm Koch

Front Mol Neurosci. 2022; 15: 1076430. Published online 2022 Dec 21. doi: 10.3389/fnmol.2022.1076430

PMCID:: PMC9812585

Abstract Article PDF–1.5M

Select item 92395815.

Natriuretic peptide receptor B maintains heart rate and sinoatrial node function via cyclic GMP-mediated signalling

Tristan W Dorey, Martin Mackasey, Hailey J Jansen, Megan D McRae, Loryn J Bohne, Yingjie Liu, Darrell D Belke, Logan Atkinson, Robert A Rose

Cardiovasc Res. 2022 May; 118(8): 1917–1931. Published online 2021 Jul 17. doi: 10.1093/cvr/cvab245

PMCID:: PMC9239581

Abstract Article PDF–1.4M

Select item 87484306.

Skeletal muscle derived Musclin protects the heart during pathological overload

Malgorzata Szaroszyk, Badder Kattih, Abel Martin-Garrido, Felix A. Trogisch, Gesine M. Dittrich, Andrea Grund, Aya Abouissa, Katja Derlin, Martin Meier, Tim Holler, Mortimer Korf-Klingebiel, Katharina Völker, Tania Garfias Macedo, Cristina Pablo Tortola, Michael Boschmann, Nora Huang, Natali Froese, Carolin Zwadlo, Mona Malek Mohammadi, Xiaojing Luo, Michael Wagner, Julio Cordero, Robert Geffers, Sandor Batkai, Thomas Thum, Nadja Bork, Viacheslav O. Nikolaev, Oliver J. Müller, Hugo A. Katus, Ali El-Armouche, Theresia Kraft, Jochen Springer, Gergana Dobreva, Kai C. Wollert, Jens Fielitz, Stephan von Haehling, Michaela Kuhn, Johann Bauersachs, Joerg Heineke

Nat Commun. 2022; 13: 149. Published online 2022 Jan 10. doi: 10.1038/s41467-021-27634-5

PMCID:: PMC8748430

Abstract Article PDF–4.5M

Select item 83132397.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 82622968.

Prevention of guanylyl cyclase–B dephosphorylation rescues achondroplastic dwarfism

Brandon M. Wagner, Jerid W. Robinson, Yun-Wen Lin, Yi-Ching Lee, Nabil Kaci, Laurence Legeai-Mallet, Lincoln R. Potter

JCI Insight. 2021 May 10; 6(9): e147832. Published online 2021 May 10. doi: 10.1172/jci.insight.147832

PMCID:: PMC8262296

Abstract Article PDF–5.6M

Select item 81112349.

Cyclic AMP links luteinizing hormone signaling to dephosphorylation and inactivation of the NPR2 guanylyl cyclase in ovarian follicles^†

Jeremy R Egbert, Jerid W Robinson, Tracy F Uliasz, Lincoln R Potter, Laurinda A Jaffe

Biol Reprod. 2021 May; 104(5): 939–941. Published online 2021 Feb 24. doi: 10.1093/biolre/ioab029

PMCID:: PMC8111234

Article PDF–345K

Select item 793877010.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 769545411.

Increasing heart vascularisation after myocardial infarction using brain natriuretic peptide stimulation of endothelial and WT1⁺ epicardial cells

Na Li, Stephanie Rignault-Clerc, Christelle Bielmann, Anne-Charlotte Bon-Mathier, Tamara Déglise, Alexia Carboni, Mégane Ducrest, Nathalie Rosenblatt-Velin

eLife. 2020; 9: e61050. Published online 2020 Nov 27. doi: 10.7554/eLife.61050

PMCID:: PMC7695454

Abstract Article PDF–12M

Select item 766084912.

Natriuretic Peptide Receptor 2 Locus Contributes to Carotid Remodeling

Vyacheslav A. Korshunov, Elaine M. Smolock, Mary E. Wines‐Samuelson, Abrar Faiyaz, Deanne M. Mickelsen, Breandan Quinn, Calvin Pan, George J. Dugbartey, Chen Yan, Marvin M. Doyley, Aldons J. Lusis, Bradford C. Berk

J Am Heart Assoc. 2020 May 18; 9(10): e014257. Published online 2020 May 12. doi: 10.1161/JAHA.119.014257

PMCID:: PMC7660849

Abstract Article PDF–4.2M

Select item 757496513.

Cellular Heterogeneity of the Luteinizing Hormone Receptor and Its Significance for Cyclic GMP Signaling in Mouse Preovulatory Follicles

Valentina Baena, Corie M Owen, Tracy F Uliasz, Katie M Lowther, Siu-Pok Yee, Mark Terasaki, Jeremy R Egbert, Laurinda A Jaffe

Endocrinology. 2020 Jul; 161(7): bqaa074. Published online 2020 May 8. doi: 10.1210/endocr/bqaa074

PMCID:: PMC7574965

Abstract Article

Select item 747961814.

Defective development and microcirculation of intestine in Npr2 mutant mice

Chizuru Sogawa-Fujiwara, Atsuki Hanagata, Yasuhiro Fujiwara, Yukisato Ishida, Hirotaka Tomiyasu, Tetsuo Kunieda, Hirofumi Nakatomi, Masatoshi Hori

Sci Rep. 2020; 10: 14761. Published online 2020 Sep 8. doi: 10.1038/s41598-020-71812-2

PMCID:: PMC7479618

Abstract Article PDF–6.2M

Select item 672422415.

The Protective Role of Natriuretic Peptide Receptor 2 against High Salt Injury in the Renal Papilla

George J. Dugbartey, Breandan Quinn, Lingfeng Luo, Deanne M. Mickelsen, Sara K. Ture, Craig N. Morrell, Jan Czyzyk, Marvin M. Doyley, Chen Yan, Bradford C. Berk, Vyacheslav A. Korshunov

Am J Pathol. 2019 Sep; 189(9): 1721–1731. doi: 10.1016/j.ajpath.2019.05.020

PMCID:: PMC6724224

Abstract Article PDF–2.6M

Select item 660834916.

Bifurcation of Axons from Cranial Sensory Neurons Is Disabled in the Absence of Npr2-Induced cGMP Signaling

Gohar Ter-Avetisyan, Fritz G. Rathjen, Hannes Schmidt

J Neurosci. 2014 Jan 15; 34(3): 737–747. doi: 10.1523/JNEUROSCI.4183-13.2014

PMCID:: PMC6608349

Abstract Article PDF–5.5M

Select item 643848717.

Endothelial C-type natriuretic peptide is a critical regulator of angiogenesis and vascular remodeling

Kristen J Bubb, Aisah A Aubdool, Amie J Moyes, Sarah Lewis, Jonathan P Drayton, Owen Tang, Vedanta Mehta, Ian C Zachary, David J Abraham, Janice Tsui, Adrian J Hobbs

Circulation. Author manuscript; available in PMC 2020 Mar 26.

Published in final edited form as: Circulation. 2019 Mar 26; 139(13): 1612–1628. doi: 10.1161/CIRCULATIONAHA.118.036344

PMCID:: PMC6438487

Abstract Article PDF–3.2M

Select item 622206118.

Regulation of the Natriuretic Peptide Receptor 2 (Npr2) by Phosphorylation of Juxtamembrane Serine and Threonine Residues Is Essential for Bifurcation of Sensory Axons

Hannes Schmidt, Deborah M. Dickey, Alexandre Dumoulin, Marie Octave, Jerid W. Robinson, Ralf Kühn, Robert Feil, Lincoln R. Potter, Fritz G. Rathjen

J Neurosci. 2018 Nov 7; 38(45): 9768–9780. doi: 10.1523/JNEUROSCI.0495-18.2018

PMCID:: PMC6222061

Abstract Article PDF–2.9M

Select item 615248419.

GC-B Deficient Mice With Axon Bifurcation Loss Exhibit Compromised Auditory Processing

Steffen Wolter, Dorit Möhrle, Hannes Schmidt, Sylvia Pfeiffer, Dennis Zelle, Philipp Eckert, Michael Krämer, Robert Feil, Peter K. D. Pilz, Marlies Knipper, Lukas Rüttiger

Front Neural Circuits. 2018; 12: 65. Published online 2018 Aug 29. doi: 10.3389/fncir.2018.00065

PMCID:: PMC6152484

Abstract Article PDF–5.4M

Select item 608742720.

C-type natriuretic peptide functions as an innate neuroprotectant in neonatal hypoxic-ischemic brain injury in mouse via natriuretic peptide receptor 2

Qingyi Ma, Lubo Zhang

Exp Neurol. Author manuscript; available in PMC 2019 Jun 1.

Published in final edited form as: Exp Neurol. 2018 Jun; 304: 58–66. Published online 2018 Mar 5. doi: 10.1016/j.expneurol.2018.02.016

PMCID:: PMC6087427

Abstract Article PDF–1.2M

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