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Select item 114086101.

Prevalent Fast Evolution of Genes Involved in Heterochromatin Functions

Leila Lin, Yuheng Huang, Jennifer McIntyre, Ching-Ho Chang, Serafin Colmenares, Yuh Chwen G Lee

Mol Biol Evol. 2024 Sep; 41(9): msae181. Published online 2024 Aug 27. doi: 10.1093/molbev/msae181

PMCID:: PMC11408610

Abstract Article PDF–1.6M

Select item 107135732.

The ubiquitin thioesterase YOD1 ameliorates mutant Huntingtin induced pathology in Drosophila

Anita Farkas, Nóra Zsindely, Gábor Nagy, Levente Kovács, Péter Deák, László Bodai

Sci Rep. 2023; 13: 21951. Published online 2023 Dec 11. doi: 10.1038/s41598-023-49241-8

PMCID:: PMC10713573

Abstract Article PDF–2.9M

Select item 104448903.

The deubiquitinase Leon/USP5 interacts with Atg1/ULK1 and antagonizes autophagy

Yueh-Ling Pai, Yuchieh Jay Lin, Wen-Hsin Peng, Li-Ting Huang, He-Yen Chou, Chien-Hsiang Wang, Cheng-Ting Chien, Guang-Chao Chen

Cell Death Dis. 2023 Aug; 14(8): 540. Published online 2023 Aug 22. doi: 10.1038/s41419-023-06062-x

PMCID:: PMC10444890

Abstract Article PDF–4.9M

Select item 100382014.

USP47 deubiquitylates Groucho/TLE to Promote Wnt-β-catenin Signaling

Sara Kassel, Alison J. Hanson, Hassina Benchabane, Kenyi Saito-Diaz, Carly R. Cabel, Lily Goldsmith, Muhammad Taha, Aksheta Kanuganti, Victoria H. Ng, George Xu, Fei Ye, Julia Picker, Fillip Port, Michael Boutros, Vivian L. Weiss, David J. Robbins, Curtis A. Thorne, Yashi Ahmed, Ethan Lee

Sci Signal. Author manuscript; available in PMC 2023 Aug 7.

Published in final edited form as: Sci Signal. 2023 Feb 7; 16(771): eabn8372. Published online 2023 Feb 7. doi: 10.1126/scisignal.abn8372

PMCID:: PMC10038201

Abstract Article PDF–1.6M

Select item 93984525.

Species-specific chromatin landscape determines how transposable elements shape genome evolution

Yuheng Huang, Harsh Shukla, Yuh Chwen G Lee

eLife. 2022; 11: e81567. Published online 2022 Aug 23. doi: 10.7554/eLife.81567

PMCID:: PMC9398452

Abstract Article PDF–5.5M

Select item 89900006.

Usp5, Usp34, and Otu1 deubiquitylases mediate DNA repair in Drosophila melanogaster

Zoltán G. Páhi, Levente Kovács, Diána Szűcs, Barbara N. Borsos, Péter Deák, Tibor Pankotai

Sci Rep. 2022; 12: 5870. Published online 2022 Apr 7. doi: 10.1038/s41598-022-09703-x

PMCID:: PMC8990000

Abstract Article PDF–1.5M

Select item 86644867.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 81297938.

Drosophila USP22/nonstop polarizes the actin cytoskeleton during collective border cell migration

Hammed Badmos, Neville Cobbe, Amy Campbell, Richard Jackson, Daimark Bennett

J Cell Biol. 2021 Jul 5; 220(7): e202007005. Published online 2021 May 14. doi: 10.1083/jcb.202007005

PMCID:: PMC8129793

Abstract Article PDF–6.5M

Select item 81182709.

RACK1 modulates polyglutamine-induced neurodegeneration by promoting ERK degradation in Drosophila

Jun Xie, Yongchao Han, Tao Wang

PLoS Genet. 2021 May; 17(5): e1009558. Published online 2021 May 13. doi: 10.1371/journal.pgen.1009558

PMCID:: PMC8118270

Abstract Article PDF–4.7M

Select item 709642510.

Proteomic mapping of Drosophila transgenic elav.L-GAL4/+ brain as a tool to illuminate neuropathology mechanisms

Athanassios D. Velentzas, Stamatia A. Katarachia, Niki E. Sagioglou, Maria M. Tsioka, Athanasios K. Anagnostopoulos, Vassiliki E. Mpakou, Eleni I. Theotoki, Aikaterini F. Giannopoulou, Konstantinos E. Keramaris, Issidora S. Papassideri, George Th. Tsangaris, Dimitrios J. Stravopodis

Sci Rep. 2020; 10: 5430. Published online 2020 Mar 25. doi: 10.1038/s41598-020-62510-0

PMCID:: PMC7096425

Abstract Article PDF–4.6M

Select item 702626811.

A Connected Network of Interacting Proteins Is Involved in Human-Tau Toxicity in Drosophila

Sébastien Feuillette, Camille Charbonnier, Thierry Frebourg, Dominique Campion, Magalie Lecourtois

Front Neurosci. 2020; 14: 68. Published online 2020 Feb 11. doi: 10.3389/fnins.2020.00068

PMCID:: PMC7026268

Abstract Article PDF–8.7M

Select item 696157812.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 626279613.

Prp8 regulates oncogene-induced hyperplastic growth in Drosophila

Cecilia H. Fernández-Espartero, Alberto Rizzo, Alexander D. Fulford, Julia Falo-Sanjuan, Damien Goutte-Gattat, Paulo S. Ribeiro

Development. 2018 Nov 15; 145(22): dev162156. Published online 2018 Nov 12. doi: 10.1242/dev.162156

PMCID:: PMC6262796

Abstract Article

Select item 607860414.

Human R1441C LRRK2 regulates the synaptic vesicle proteome and phosphoproteome in a Drosophila model of Parkinson’s disease

Md Shariful Islam, Hendrik Nolte, Wright Jacob, Anna B. Ziegler, Stefanie Pütz, Yael Grosjean, Karolina Szczepanowska, Aleksandra Trifunovic, Thomas Braun, Hermann Heumann, Rolf Heumann, Bernhard Hovemann, Darren J. Moore, Marcus Krüger

Hum Mol Genet. 2016 Dec 15; 25(24): 5365–5382. Published online 2016 Oct 29. doi: 10.1093/hmg/ddw352

PMCID:: PMC6078604

Abstract Article PDF–1.9M

Select item 570780515.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 568900216.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 499495717.

The Deubiquitinase USP47 Stabilizes MAPK by Counteracting the Function of the N-end Rule ligase POE/UBR4 in Drosophila

Dariel Ashton-Beaucage, Caroline Lemieux, Christian M. Udell, Malha Sahmi, Samuel Rochette, Marc Therrien

PLoS Biol. 2016 Aug; 14(8): e1002539. Published online 2016 Aug 23. doi: 10.1371/journal.pbio.1002539

PMCID:: PMC4994957

Abstract Article PDF–9.0M

Select item 498783318.

Deubiquitinase Usp8 regulates α-synuclein clearance and modifies its toxicity in Lewy body disease

Zoi Alexopoulou, Johannes Lang, Rebecca M. Perrett, Myriam Elschami, Madeleine E. D. Hurry, Hyoung Tae Kim, Dimitra Mazaraki, Aron Szabo, Benedikt M. Kessler, Alfred Lewis Goldberg, Olaf Ansorge, Tudor A. Fulga, George K. Tofaris

Proc Natl Acad Sci U S A. 2016 Aug 9; 113(32): E4688–E4697. Published online 2016 Jul 21. doi: 10.1073/pnas.1523597113