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Select item 113993951.

RUNX1 interacts with lncRNA SMANTIS to regulate monocytic cell functions

Lisa M. Weiss, Timothy Warwick, Simonida Zehr, Stefan Günther, Sebastian Wolf, Tessa Schmachtel, Judit Izquierdo Ponce, Katalin Pálfi, Tom Teichmann, Alicia Schneider, Julia Stötzel, Stefan Knapp, Andreas Weigert, Rajkumar Savai, Michael A. Rieger, Thomas Oellerich, Ilka Wittig, James A. Oo, Ralf P. Brandes, Matthias S. Leisegang

Commun Biol. 2024; 7: 1131. Published online 2024 Sep 13. doi: 10.1038/s42003-024-06794-2

PMCID:: PMC11399395

Abstract Article PDF–2.9M

Select item 113790742.

RUNX1-PDIA5 Axis Promotes Malignant Progression of Glioblastoma by Regulating CCAR1 Protein Expression

Qiankun Ji, Zewei Tu, Junzhe Liu, Zhihong Zhou, Fengze Li, Xingen Zhu, Kai Huang

Int J Biol Sci. 2024; 20(11): 4364–4381. Published online 2024 Aug 12. doi: 10.7150/ijbs.92595

PMCID:: PMC11379074

Abstract Article PDF–11M

Select item 111587203.

RUNX1/EVI1, which blocks myeloid differentiation, inhibits CCAAT–enhancer binding protein α function

Katsuya Tokita, Kazuhiro Maki, Kinuko Mitani

Cancer Sci. 2007 Nov; 98(11): 1752–1757. Published online 2007 Aug 23. doi: 10.1111/j.1349-7006.2007.00597.x

PMCID:: PMC11158720

Abstract Article PDF–197K

Select item 111117804.

RUNX1-induced upregulation of PTGS2 enhances cell growth, migration and invasion in colorectal cancer cells

Weiwei Zheng, Yingchang Guo, Aihemaiti Kahar, Junwei Bai, Qinhui Zhu, Xinli Huang, Yuan Li, Bingyi Xu, Xueshan Jia, Gang Wu, Chao Zhang, Yuanzeng Zhu

Sci Rep. 2024; 14: 11670. Published online 2024 May 22. doi: 10.1038/s41598-024-60296-z

PMCID:: PMC11111780

Abstract Article PDF–6.6M

Select item 110631895.

The role of RUNX1/NF-κB in regulating PVAT inflammation in aortic dissection

Ao Wang, Shengjun Dong, Baohui Liu, Dianxiao Liu, Mingrui Zou, Yuexin Han, Lijuan Yang, Yujiu Wang

Sci Rep. 2024; 14: 9960. Published online 2024 Apr 30. doi: 10.1038/s41598-024-60737-9

PMCID:: PMC11063189

Abstract Article PDF–4.8M

Select item 110104296.

RUNX1-BMP2 promotes vasculogenic mimicry in laryngeal squamous cell carcinoma via activation of the PI3K-AKT signaling pathway

Qingwen Zhu, Xinyu Zhang, Fei Lu, Siyu Miao, Chunyang Zhang, Zhenzhen Liu, Zejun Gao, Meihao Qi, Xiaogang An, Panling Geng, Sufang Wang, Hongbo Ren, Fugen Han, Ruyue Zhang, DingJun Zha

Cell Commun Signal. 2024; 22: 227. Published online 2024 Apr 12. doi: 10.1186/s12964-024-01605-x

PMCID:: PMC11010429

Abstract Article PDF–8.2M

Select item 110098687.

RUNX1 mutations mitigate quiescence to promote transformation of hematopoietic progenitors in Fanconi anemia

William Marion, Tiago Koppe, Chun-Chin Chen, Dahai Wang, Katie Frenis, Sara Fierstein, Prerana Sensharma, Olivia Aumais, Michael Peters, Sonya Ruiz-Torres, Tafadzwa Chihanga, Steffen Boettcher, Akiko Shimamura, Daniel E. Bauer, Thorsten Schlaeger, Susanne I. Wells, Benjamin L. Ebert, Daniel Starczynowski, Edroaldo Lummertz da Rocha, R. Grant Rowe

Leukemia. Author manuscript; available in PMC 2024 Jun 1.

Published in final edited form as: Leukemia. 2023 Aug; 37(8): 1698–1708. Published online 2023 Jun 30. doi: 10.1038/s41375-023-01945-6

PMCID:: PMC11009868

Abstract Article PDF–1.0M

Select item 109979148.

Altered platelet-megakaryocyte endocytosis and trafficking of albumin and fibrinogen in RUNX1 haplodeficiency

Fabiola Del Carpio-Cano, Guangfen Mao, Lawrence E. Goldfinger, Jeremy Wurtzel, Liying Guan, Mohammad Afaque Alam, Kiwon Lee, Mortimer Poncz, A. Koneti Rao

Blood Adv. 2024 Apr 9; 8(7): 1699–1714. Published online 2024 Feb 10. doi: 10.1182/bloodadvances.2023011098

PMCID:: PMC10997914

Abstract Article PDF–4.8M

Select item 109219199.

Liangjun Zhang, Qiong Pan, Lu Zhang, Haihan Xia, Junwei Liao, Xiaoxun Zhang, Nan Zhao, Qiaoling Xie, Min Liao, Ya Tan, Qiao Li, Jinfei Zhu, Ling Li, Shijun Fan, Jianwei Li, Chengcheng Zhang, Shi-Ying Cai, James L. Boyer, Jin Chai

Hepatology. Author manuscript; available in PMC 2024 Mar 8.

Published in final edited form as: Hepatology. 2023 Jun 1; 77(6): 1866–1881. Published online 2023 Jan 3. doi: 10.1097/HEP.0000000000000041

PMCID:: PMC10921919

Abstract Article PDF–3.1M

Select item 1083719610.

Genomic landscape of patients with germline RUNX1 variants and familial platelet disorder with myeloid malignancy

Kai Yu, Natalie Deuitch, Matthew Merguerian, Lea Cunningham, Joie Davis, Erica Bresciani, Jamie Diemer, Elizabeth Andrews, Alice Young, Frank Donovan, Raman Sood, Kathleen Craft, Shawn Chong, Settara Chandrasekharappa, Jim Mullikin, Paul P. Liu

Blood Adv. 2024 Jan 23; 8(2): 497–511. Published online 2023 Nov 29. doi: 10.1182/bloodadvances.2023011165

PMCID:: PMC10837196

Abstract Article PDF–2.7M

Select item 1076740011.

Hematopoietic Transcription Factor RUNX1 is Essential for Promoting Macrophage–Myofibroblast Transition in Non‐Small‐Cell Lung Carcinoma

Philip Chiu‐Tsun Tang, Max Kam‐Kwan Chan, Jeff Yat‐Fai Chung, Alex Siu‐Wing Chan, Dongmei Zhang, Chunjie Li, Kam‐Tong Leung, Calvin Sze‐Hang Ng, Yi Wu, Ka‐Fai To, Hui‐Yao Lan, Patrick Ming‐Kuen Tang

Adv Sci (Weinh) 2024 Jan; 11(1): 2302203. Published online 2023 Nov 15. doi: 10.1002/advs.202302203

PMCID:: PMC10767400

Abstract Article PDF–27M

Select item 1076347112.

MYCT1 inhibits hematopoiesis in diffuse large B-cell lymphoma by suppressing RUNX1 transcription

Ying Liang, Xin Wei, Peng-Jie Yue, He-Cheng Zhang, Zhen-Ning Li, Xiao-Xue Wang, Yuan-Yuan Sun, Wei-Neng Fu

Cell Mol Biol Lett. 2024; 29: 5. Published online 2024 Jan 3. doi: 10.1186/s11658-023-00522-0

PMCID:: PMC10763471

Abstract Article PDF–3.0M

Select item 1070212413.

RUNX1 knockdown induced apoptosis and impaired EMT in high-grade serous ovarian cancer cells

Yuanzhi Chen, Zhicheng He, Shuting Yang, Cheng Chen, Wenyong Xiong, YingYing He, Shubai Liu

J Transl Med. 2023; 21: 886. Published online 2023 Dec 6. doi: 10.1186/s12967-023-04762-8

PMCID:: PMC10702124

Abstract Article PDF–4.3M

Select item 1065187314.

Hereditary platelet disorders associated with germ line variants in RUNX1, ETV6, and ANKRD26

Claire C. Homan, Hamish S. Scott, Anna L. Brown

Blood. 2023 Mar 30; 141(13): 1533–1543. Published online 2023 Jan 13. doi: 10.1182/blood.2022017735

PMCID:: PMC10651873

Abstract Article

Select item 1058238215.

Somatic mutational landscape of hereditary hematopoietic malignancies caused by germline variants in RUNX1, GATA2, and DDX41

Claire C. Homan, Michael W. Drazer, Kai Yu, David M. Lawrence, Jinghua Feng, Luis Arriola-Martinez, Matthew J. Pozsgai, Kelsey E. McNeely, Thuong Ha, Parvathy Venugopal, Peer Arts, Sarah L. King-Smith, Jesse Cheah, Mark Armstrong, Paul Wang, Csaba Bödör, Alan B. Cantor, Mario Cazzola, Erin Degelman, Courtney D. DiNardo, Nicolas Duployez, Remi Favier, Stefan Fröhling, Ana Rio-Machin, Jeffery M. Klco, Alwin Krämer, Mineo Kurokawa, Joanne Lee, Luca Malcovati, Neil V. Morgan, Georges Natsoulis, Carolyn Owen, Keyur P. Patel, Claude Preudhomme, Hana Raslova, Hugh Rienhoff, Tim Ripperger, Rachael Schulte, Kiran Tawana, Elvira Velloso, Benedict Yan, Erika Kim, Raman Sood, NISC Comparative Sequencing Program, Amy P. Hsu, Steven M. Holland, Kerry Phillips, Nicola K. Poplawski, Milena Babic, Andrew H. Wei, Cecily Forsyth, Helen Mar Fan, Ian D. Lewis, Julian Cooney, Rachel Susman, Lucy C. Fox, Piers Blombery, Deepak Singhal, Devendra Hiwase, Belinda Phipson, Andreas W. Schreiber, Christopher N. Hahn, Hamish S. Scott, Paul Liu, Lucy A. Godley, Anna L. Brown

Blood Adv. 2023 Oct 24; 7(20): 6092–6107. Published online 2023 Jul 7. doi: 10.1182/bloodadvances.2023010045

PMCID:: PMC10582382

Abstract Article PDF–1.6M

Select item 1056587616.

Pulse-SILAC and Interactomics Reveal Distinct DDB1-CUL4–Associated Factors, Cellular Functions, and Protein Substrates

Jennifer Raisch, Marie-Line Dubois, Marika Groleau, Dominique Lévesque, Thomas Burger, Carla-Marie Jurkovic, Romain Brailly, Gwendoline Marbach, Alyson McKenna, Catherine Barrette, Pierre-Étienne Jacques, François-Michel Boisvert

Mol Cell Proteomics. 2023 Oct; 22(10): 100644. Published online 2023 Sep 7. doi: 10.1016/j.mcpro.2023.100644