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Select item 105308311.

Functional Variation in the FAAH Gene Is Directly Associated with Subjective Well-Being and Indirectly Associated with Problematic Alcohol Use

Lisa Bornscheuer, Andreas Lundin, Yvonne Forsell, Catharina Lavebratt, Philippe A. Melas

Genes (Basel) 2023 Sep; 14(9): 1826. Published online 2023 Sep 21. doi: 10.3390/genes14091826

PMCID:: PMC10530831

Abstract Article PDF–501K

Select item 102983912.

Association of FAAH rs324420 (C385A) Polymorphism with High-Level Performance in Volleyball Players

Hugo-Henrique Silva, Valéria Tavares, Maria-Raquel G. Silva, Beatriz Vieira Neto, Fátima Cerqueira, Rui Medeiros

Genes (Basel) 2023 Jun; 14(6): 1164. Published online 2023 May 26. doi: 10.3390/genes14061164

PMCID:: PMC10298391

Abstract Article PDF–736K

Select item 102295443.

Identification of fatty acid amide hydrolase as a metastasis suppressor in breast cancer

Isabel Tundidor, Marta Seijo-Vila, Sandra Blasco-Benito, María Rubert-Hernández, Sandra Adámez, Clara Andradas, Sara Manzano, Isabel Álvarez-López, Cristina Sarasqueta, María Villa-Morales, Carmen González-Lois, Esther Ramírez-Medina, Belén Almoguera, Antonio J. Sánchez-López, Laura Bindila, Sigrid Hamann, Norbert Arnold, Christoph Röcken, Ignacio Heras-Murillo, David Sancho, Gema Moreno-Bueno, María M. Caffarel, Manuel Guzmán, Cristina Sánchez, Eduardo Pérez-Gómez

Nat Commun. 2023; 14: 3130. Published online 2023 May 30. doi: 10.1038/s41467-023-38750-9

PMCID:: PMC10229544

Abstract Article PDF–2.5M

Select item 96533644.

FAAH polymorphism (rs324420) modulates extinction recall in healthy humans: an fMRI study

Jennifer Spohrs, Martin Ulrich, Georg Grön, Paul L. Plener, Birgit Abler

Eur Arch Psychiatry Clin Neurosci. 2022; 272(8): 1495–1504. Published online 2021 Dec 10. doi: 10.1007/s00406-021-01367-4

PMCID:: PMC9653364

Abstract Article PDF–795K

Select item 90419715.

Association of FAAH p.Pro129Thr and COMT p.Ala72Ser with schizophrenia and comorbid substance use through next-generation sequencing: an exploratory analysis

José J. Martínez-Magaña, Alma D. Genis-Mendoza, Vanessa González-Covarrubias, Isela E. Juárez-Rojop, Carlos A. Tovilla-Zárate, Xavier Soberón, Nuria Lanzagorta, Humberto Nicolini

Braz J Psychiatry. 2022 Mar-Apr; 44(2): 164–170. Published online 2021 May 21. doi: 10.1590/1516-4446-2020-1546

PMCID:: PMC9041971

Abstract Article PDF–132K

Select item 87828626.

Higher trait neuroticism is associated with greater fatty acid amide hydrolase binding in borderline and antisocial personality disorders

Nathan J. Kolla, Isabelle Boileau, R. Michael Bagby

Sci Rep. 2022; 12: 1126. Published online 2022 Jan 21. doi: 10.1038/s41598-022-04789-9

PMCID:: PMC8782862

Abstract Article PDF–1.5M

Select item 86280267.

A common genetic variant in fatty acid amide hydrolase is linked to alterations in fear extinction neural circuitry in a racially diverse, nonclinical sample of adults

Nicole L. Zabik, Allesandra S. ladipaolo, Hilary A. Marusak, Craig Peters, Kyle Burghardt, Christine A. Rabinak

J Neurosci Res. Author manuscript; available in PMC 2022 Mar 1.

Published in final edited form as: J Neurosci Res. 2022 Mar; 100(3): 744–761. Published online 2021 May 29. doi: 10.1002/jnr.24860

PMCID:: PMC8628026

Abstract Article PDF–971K

Select item 82404778.

Imaging brain fatty acid amide hydrolase in untreated patients with psychosis

Jeremy J Watts, Maya R Jacobson, Nittha Lalang, Isabelle Boileau, Rachel F Tyndale, Michael Kiang, Ruth A Ross, Sylvain Houle, Alan A Wilson, Pablo Rusjan, Romina Mizrahi

Biol Psychiatry. Author manuscript; available in PMC 2021 Nov 1.

Published in final edited form as: Biol Psychiatry. 2020 Nov 1; 88(9): 727–735. Published online 2020 Mar 12. doi: 10.1016/j.biopsych.2020.03.003

PMCID:: PMC8240477

Abstract Article PDF–589K

Select item 81650309.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 806173310.

Fatty acid amide hydrolase binding is inversely correlated with amygdalar functional connectivity: a combined positron emission tomography and magnetic resonance imaging study in healthy individuals

Duncan G.J. Green, Jinhee Kim, Stephen J. Kish, Rachel F. Tyndale, Matthew N. Hill, Antonio P. Strafella, Junchao Tong, Tina McCluskey, Duncan J. Westwood, Sylvain Houle, Nancy J. Lobaugh, Isabelle Boileau

J Psychiatry Neurosci. 2021 Mar; 46(2): 238–246. doi: 10.1503/jpn.200010

PMCID:: PMC8061733

Abstract Article PDF–549K

Select item 751202111.

The fatty-acid amide hydrolase inhibitor URB597 inhibits MICA/B shedding

Kazuma Sekiba, Motoyuki Otsuka, Takahiro Seimiya, Eri Tanaka, Kazuyoshi Funato, Yu Miyakawa, Kazuhiko Koike

Sci Rep. 2020; 10: 15556. Published online 2020 Sep 23. doi: 10.1038/s41598-020-72688-y

PMCID:: PMC7512021

Abstract Article PDF–3.4M

Select item 721785012.

Do AKT1, COMT and FAAH influence reports of acute cannabis intoxication experiences in patients with first episode psychosis, controls and young adult cannabis users?

Chandni Hindocha, Diego Quattrone, Tom P. Freeman, Robin M. Murray, Valeria Mondelli, Gerome Breen, Charles Curtis, Celia J. A. Morgan, H. Valerie Curran, Marta Di Forti

Transl Psychiatry. 2020; 10: 143. Published online 2020 May 12. doi: 10.1038/s41398-020-0823-9

PMCID:: PMC7217850

Abstract Article PDF–524K

Select item 707590613.

D3 dopamine receptors and a missense mutation of fatty acid amide hydrolase linked in mouse and men: implication for addiction

Esmaeil Mansouri, José N. Nobrega, Matthew N. Hill, Rachel F. Tyndale, Francis S. Lee, Christian S. Hendershot, Laura M. Best, Patricia Di Ciano, Georgia Balsevich, Mathew E. Sloan, Stephen J. Kish, Junchao Tong, Bernard Le Foll, Isabelle Boileau

Neuropsychopharmacology. 2020 Apr; 45(5): 745–752. Published online 2019 Nov 27. doi: 10.1038/s41386-019-0580-8

PMCID:: PMC7075906

Abstract Article PDF–830K

Select item 701075114.

The endocannabinoid hydrolase FAAH is an allosteric enzyme

Enrico Dainese, Sergio Oddi, Monica Simonetti, Annalaura Sabatucci, Clotilde B. Angelucci, Alice Ballone, Beatrice Dufrusine, Filomena Fezza, Gianni De Fabritiis, Mauro Maccarrone

Sci Rep. 2020; 10: 2292. Published online 2020 Feb 10. doi: 10.1038/s41598-020-59120-1

Correction in:: Sci Rep. 2020; 10: 5903.

PMCID:: PMC7010751

Abstract Article PDF–1.6M

Select item 674104315.

Cannabinoid CB₂ Receptors and Fatty Acid Amide Hydrolase Are Selectively Overexpressed in Neuritic Plaque-Associated Glia in Alzheimer's Disease Brains

Cristina Benito, Estefanía Núñez, Rosa M. Tolón, Erica J. Carrier, Alberto Rábano, Cecilia J. Hillard, Julián Romero

J Neurosci. 2003 Dec 3; 23(35): 11136–11141. doi: 10.1523/JNEUROSCI.23-35-11136.2003

PMCID:: PMC6741043

Abstract Article PDF–255K

Select item 667600916.

Microdeletion in a FAAH pseudogene identified in a patient with high anandamide concentrations and pain insensitivity

Abdella M. Habib, Andrei L. Okorokov, Matthew N. Hill, Jose T. Bras, Man-Cheung Lee, Shengnan Li, Samuel J. Gossage, Marie van Drimmelen, Maria Morena, Henry Houlden, Juan D. Ramirez, David L.H. Bennett, Devjit Srivastava, James J. Cox

Br J Anaesth. 2019 Aug; 123(2): e249–e253. Published online 2019 Mar 28. doi: 10.1016/j.bja.2019.02.019

PMCID:: PMC6676009

Abstract Article PDF–335K

Select item 666836217.

OPRM1 rs1799971 - COMT rs4680 - FAAH rs324420 genes interact with placebo procedures to induce hypoalgesia

Luana Colloca, Yang Wang, Pedro E. Martinez, Yen-Pei Christy Chang, Kathleen A. Ryan, Colin Hodgkinson, David Goldman, Susan G. Dorsey

Pain. Author manuscript; available in PMC 2020 Aug 1.

Published in final edited form as: Pain. 2019 Aug; 160(8): 1824–1834. doi: 10.1097/j.pain.0000000000001578

PMCID:: PMC6668362

Abstract Article PDF–1.3M

Select item 645216818.

Evaluating the Association of FAAH Common Gene Variation with Childhood, Adult Severe Obesity and Type 2 Diabetes in the French Population

Emmanuelle Durand, Cécile Lecoeur, Jérôme Delplanque, Michael Benzinou, Franck Degraeve, Philippe Boutin, Michel Marre, Beverley Balkau, Guillaume Charpentier, Philippe Froguel, David Meyre

Obes Facts. 2008 Dec; 1(6): 305–309. Published online 2008 Dec 12. doi: 10.1159/000178157

PMCID:: PMC6452168

Abstract Article PDF–139K

Select item 584953419.

Genome-wide CRISPR-Cas9 screen identifies leukemia-specific dependence on a pre-mRNA metabolic pathway regulated by DCPS

Takuji Yamauchi, Takeshi Masuda, Matthew C. Canver, Michael Seiler, Yuichiro Semba, Mohammad Shboul, Mohammed Al-Raqad, Manami Maeda, Vivien A. C. Schoonenberg, Mitchel A. Cole, Claudio Macias-Trevino, Yuichi Ishikawa, Qiuming Yao, Michitaka Nakano, Fumio Arai, Stuart H. Orkin, Bruno Reversade, Silvia Buonamici, Luca Pinello, Koichi Akashi, Daniel E. Bauer, Takahiro Maeda

Cancer Cell. Author manuscript; available in PMC 2019 Mar 12.

Published in final edited form as: Cancer Cell. 2018 Mar 12; 33(3): 386–400.e5. Published online 2018 Feb 22. doi: 10.1016/j.ccell.2018.01.012

PMCID:: PMC5849534

Abstract Article PDF–1.1M

Select item 574834120.

FAAH gene variation moderates stress response and symptom severity in patients with post-traumatic stress disorder and comorbid alcohol dependence

Primavera A. Spagnolo, Vijay A. Ramchandani, Melanie L. Schwandt, Laura E. Kwako, David T. George, Cecilia J. Hillard, Markus Heilig

Alcohol Clin Exp Res. Author manuscript; available in PMC 2018 Jan 1.

Published in final edited form as: Alcohol Clin Exp Res. 2016 Nov; 40(11): 2426–2434. Published online 2016 Sep 26. doi: 10.1111/acer.13210

PMCID:: PMC5748341

Abstract Article PDF–1.6M

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