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Select item 92316231.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 86705362.

Characterization of tolloid-mediated cleavage of the GDF8 procomplex

Jason C. McCoy, Erich J. Goebel, Thomas B. Thompson

Biochem J. Author manuscript; available in PMC 2021 Dec 14.

Published in final edited form as: Biochem J. 2021 May 14; 478(9): 1733–1747. doi: 10.1042/BCJ20210054

PMCID:: PMC8670536

Abstract Article PDF–1.6M

Select item 82302933.

Association between Interferon-Lambda-3 rs12979860, TLL1 rs17047200 and DDR1 rs4618569 Variant Polymorphisms with the Course and Outcome of SARS-CoV-2 Patients

Sara H. A. Agwa, Marwa Mostafa Kamel, Hesham Elghazaly, Aya M. Abd Elsamee, Hala Hafez, Samia Abdo Girgis, Hoda Ezz Elarab, Fatma S. E. Ebeid, Safa Matbouly Sayed, Lina Sherif, Marwa Matboli

Genes (Basel) 2021 Jun; 12(6): 830. Published online 2021 May 28. doi: 10.3390/genes12060830

PMCID:: PMC8230293

Abstract Article PDF–255K

Select item 81650304.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 77321065.

Genetic variation in the TLL1 gene is not associated with fibrosis in patients with metabolic associated fatty liver disease

Ali Bayoumi, Ismail Jalil, Mayada Metwally, Leon A. Adams, Rocio Aller, Carmelo García-Monzón, María Teresa Arias-Loste, Luca Miele, Salvatore Petta, Antonio Craxì, Rocio Gallego-Durán, Janett Fischer, Thomas Berg, Liang Qiao, Christopher Liddle, Elisabetta Bugianesi, Manuel Romero-Gomez, Jacob George, Mohammed Eslam

PLoS One. 2020; 15(12): e0243590. Published online 2020 Dec 11. doi: 10.1371/journal.pone.0243590

PMCID:: PMC7732106

Abstract Article PDF–786K

Select item 63288696.

Functional and structural studies of tolloid-like 1 mutants associated with atrial-septal defect 6

Lukasz Sieron, Marta Lesiak, Izabela Schisler, Zofia Drzazga, Andrzej Fertala, Aleksander L. Sieron

Biosci Rep. 2019 Jan 31; 39(1): BSR20180270. Prepublished online 2018 Dec 11. Published online 2019 Jan 8. doi: 10.1042/BSR20180270

PMCID:: PMC6328869

Abstract Article PDF–1.0M

Select item 61800457.

Tolloid-like 1 genetic variants determine fibrosis regression in chronic hepatitis C patients with curative antivirals

Chung-Feng Huang, Ming-Lun Yeh, Ching-I Huang, Zu-Yau Lin, Shinn-Cherng Chen, Jee-Fu Huang, Chia-Yen Dai, Wan-Long Chuang, Jyh-Jou Chen, Ming-Lung Yu

Sci Rep. 2018; 8: 15058. Published online 2018 Oct 10. doi: 10.1038/s41598-018-33448-1

PMCID:: PMC6180045

Abstract Article PDF–1023K

Select item 55316118.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 54952259.

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing

Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114

PMCID:: PMC5495225

Abstract Article PDF–1.3M

Select item 396394410.

Gene Expression Analysis of a Panel of Cell Lines That Differentially Restrict HIV-1 CA Mutants Infection in a Cyclophilin A-Dependent Manner

Vaibhav B. Shah, Christopher Aiken

PLoS One. 2014; 9(3): e92724. Published online 2014 Mar 24. doi: 10.1371/journal.pone.0092724

PMCID:: PMC3963944

Abstract Article PDF–187K

Select item 387876611.

Structural and functional evidence for a substrate exclusion mechanism in mammalian tolloid like-1 (TLL-1) proteinase

Richard Berry, Thomas A. Jowitt, Laure Garrigue-Antar, Karl E. Kadler, Clair Baldock

FEBS Lett. 2010 Feb 19; 584(4): 657–661. doi: 10.1016/j.febslet.2009.12.050

PMCID:: PMC3878766

Abstract Article

Select item 381014812.

Genome-wide Association Study Identifies New Susceptibility Loci for Posttraumatic Stress Disorder

Pingxing Xie, Henry R. Kranzler, Can Yang, Hongyu Zhao, Lindsay A. Farrer, Joel Gelernter

Biol Psychiatry. Author manuscript; available in PMC 2013 Nov 1.

Published in final edited form as: Biol Psychiatry. 2013 Nov 1; 74(9): 10.1016/j.biopsych.2013.04.013. Published online 2013 May 28. doi: 10.1016/j.biopsych.2013.04.013

PMCID:: PMC3810148

Abstract Article PDF–319K

Select item 362997213.

PPAR-Pathway Gene Polymorphism Associated with Extent of Coronary Artery Disease in Patients with Type 2 Diabetes in the BARI 2D Trial

Sharon Cresci, Jun Wu, Michael A. Province, John A. Spertus, Michael Steffes, Janet B. McGill, Edwin L. Alderman, Maria Mori Brooks, Sheryl F. Kelsey, Robert L. Frye, Richard G. Bach, the BARI 2D Study Group

Circulation. Author manuscript; available in PMC 2013 Apr 18.

Published in final edited form as: Circulation. 2011 Sep 27; 124(13): 1426–1434. Published online 2011 Sep 12. doi: 10.1161/CIRCULATIONAHA.111.029173

PMCID:: PMC3629972

Abstract Article PDF–989K

Select item 361370914.

A genome-wide association study of brain lesion distribution in multiple sclerosis

Pierre-Antoine Gourraud, Michael Sdika, Pouya Khankhanian, Roland G. Henry, Azadeh Beheshtian, Paul M. Matthews, Stephen L. Hauser, Jorge R. Oksenberg, Daniel Pelletier, Sergio E. Baranzini

Brain. 2013 Apr; 136(4): 1012–1024. Published online 2013 Feb 13. doi: 10.1093/brain/aws363

PMCID:: PMC3613709

Abstract Article PDF–1.4M

Select item 352258715.

Novel Genetic Loci Identified for the Pathophysiology of Childhood Obesity in the Hispanic Population

Anthony G. Comuzzie, Shelley A. Cole, Sandra L. Laston, V. Saroja Voruganti, Karin Haack, Richard A. Gibbs, Nancy F. Butte

PLoS One. 2012; 7(12): e51954. Published online 2012 Dec 14. doi: 10.1371/journal.pone.0051954

PMCID:: PMC3522587

Abstract Article PDF–130K

Select item 319082616.

Interactions of Pathological Hallmark Proteins: TUBULIN POLYMERIZATION PROMOTING PROTEIN/p25, β-AMYLOID, AND α-SYNUCLEIN

Judit Oláh, Orsolya Vincze, Dezső Virók, Dóra Simon, Zsolt Bozsó, Natália Tőkési, István Horváth, Emma Hlavanda, János Kovács, Anna Magyar, Mária Szűcs, Ferenc Orosz, Botond Penke, Judit Ovádi

J Biol Chem. 2011 Sep 30; 286(39): 34088–34100. Published online 2011 Aug 8. doi: 10.1074/jbc.M111.243907

PMCID:: PMC3190826

Abstract Article PDF–5.7M

Select item 317805917.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 298616718.

Mutations in mammalian tolloid-like 1 gene detected in adult patients with ASD

Paweł Stańczak, Joanna Witecka, Anna Szydło, Ewa Gutmajster, Małgorzata Lisik, Aleksandra Auguściak-Duma, Maciej Tarnowski, Tomasz Czekaj, Hanna Czekaj, Aleksander L Sieroń

Eur J Hum Genet. 2009 Mar; 17(3): 344–351. Published online 2008 Oct 1. doi: 10.1038/ejhg.2008.175

PMCID:: PMC2986167

Abstract Article PDF–160K

Select item 289646419.

Personalized Smoking Cessation: Interactions between Nicotine Dose, Dependence and Quit-Success Genotype Score

Jed E Rose, Frédérique M Behm, Tomas Drgon, Catherine Johnson, George R Uhl

Mol Med. 2010 Jul-Aug; 16(7-8): 247–253. Published online 2010 Mar 17. doi: 10.2119/molmed.2009.00159

Correction in:: Mol Med. 2012; 18(1): 729.

PMCID:: PMC2896464

Abstract Article PDF–2.4M

Select item 275479920.

Activation of Mammalian Tolloid-Like 1 Expression by Hypoxia in Human Neuroblastoma SH-SY5Y Cells

Inna B. Sabirzhanova, Boris E. Sabirzhanov, Joyce Keifer, Timothy G. Clark

Biochem Biophys Res Commun. Author manuscript; available in PMC 2010 Nov 13.

Published in final edited form as: Biochem Biophys Res Commun. 2009 Nov 13; 389(2): 338–342. Published online 2009 Aug 31. doi: 10.1016/j.bbrc.2009.08.146

PMCID:: PMC2754799

Abstract Article PDF–221K

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