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Items: 1 to 20 of 57

1.
Brain-specific glycosylation enzyme GnT-IX maintains levels of protein tyrosine phosphatase receptor PTPRZ, thereby mediating glioma growth
Kenichiro Nagai, Yui Muto, Saori Miura, Kazuto Takahashi, Yu Naruse, Ryo Hiruta, Yuko Hashimoto, Miwa Uzuki, Yoshimi Haga, Risa Fujii, Koji Ueda, Yasushi Kawaguchi, Masazumi Fujii, Shinobu Kitazume
J Biol Chem. 2023 Sep; 299(9): 105128. Published online 2023 Aug 4. doi: 10.1016/j.jbc.2023.105128
PMCID:
PMC10480537
AbstractArticlePDF–3.2M
2.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
3.
The Glycoprotein M6a Is Associated with Invasiveness and Radioresistance of Glioblastoma Stem Cells
Marie Geraldine Lacore, Caroline Delmas, Yvan Nicaise, Aline Kowalski-Chauvel, Elizabeth Cohen-Jonathan-Moyal, Catherine Seva
Cells. 2022 Jul; 11(14): 2128. Published online 2022 Jul 6. doi: 10.3390/cells11142128
PMCID:
PMC9321762
AbstractArticlePDF–2.6M
4.
Protein Tyrosine Phosphatase Receptor Type Z in Central Nervous System Disease
Kenichiro Nagai, Masazumi Fujii, Shinobu Kitazume
Int J Mol Sci. 2022 Apr; 23(8): 4414. Published online 2022 Apr 16. doi: 10.3390/ijms23084414
PMCID:
PMC9024684
AbstractArticlePDF–1.2M
5.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
6.
High‐sensitive clinical diagnostic method for PTPRZ1‐MET and the characteristic protein structure contributing to ligand‐independent MET activation
Ruoyu Huang, Yanwei Liu, Kuanyu Wang, Zheng Wang, Chuanbao Zhang, Wei Zhang, Zheng Zhao, Guanzhang Li, Lijie Huang, Yuanhao Chang, Fan Zeng, Tao Jiang, Huimin Hu
CNS Neurosci Ther. 2021 May; 27(5): 617–628. Published online 2021 Feb 28. doi: 10.1111/cns.13627
PMCID:
PMC8025647
AbstractArticlePDF–2.2M
7.
A novel PTPRZ1‐ETV1 fusion in gliomas
Alenka Matjašič, Andrej Zupan, Emanuela Boštjančič, Jože Pižem, Mara Popović, Danijela Kolenc
Brain Pathol. 2020 Mar; 30(2): 226–234. Published online 2019 Aug 27. doi: 10.1111/bpa.12776
PMCID:
PMC8018154
AbstractArticlePDF–525K
8.
Chemotherapy-driven increases in the CDKN1A/PTN/PTPRZ1 axis promote chemoresistance by activating the NF-κB pathway in breast cancer cells
Peng Huang, Deng-jie Ouyang, Shi Chang, Mo-yun Li, Lun Li, Qian-ying Li, Rong Zeng, Qiong-yan Zou, Juan Su, Piao Zhao, Lei Pei, Wen-jun Yi
Cell Commun Signal. 2018; 16: 92. Published online 2018 Nov 29. doi: 10.1186/s12964-018-0304-4
PMCID:
PMC6267809
AbstractArticlePDF–4.8M
9.
Estrogen-regulated feedback loop limits the efficacy of estrogen receptor–targeted breast cancer therapy
Tengfei Xiao, Wei Li, Xiaoqing Wang, Han Xu, Jixin Yang, Qiu Wu, Ying Huang, Joseph Geradts, Peng Jiang, Teng Fei, David Chi, Chongzhi Zang, Qi Liao, Jonathan Rennhack, Eran Andrechek, Nanlin Li, Simone Detre, Mitchell Dowsett, Rinath M. Jeselsohn, X. Shirley Liu, Myles Brown
Proc Natl Acad Sci U S A. 2018 Jul 31; 115(31): 7869–7878. Published online 2018 Jul 9. doi: 10.1073/pnas.1722617115
PMCID:
PMC6077722
AbstractArticlePDF–2.4M
10.
Alterations in the brain interactome of the intrinsically disordered N-terminal domain of the cellular prion protein (PrPC) in Alzheimer’s disease
Sarah Ulbrich, Petra Janning, Ralf Seidel, Jakob Matschke, Anika Gonsberg, Sebastian Jung, Markus Glatzel, Martin Engelhard, Konstanze F. Winklhofer, Jörg Tatzelt
PLoS One. 2018; 13(5): e0197659. Published online 2018 May 23. doi: 10.1371/journal.pone.0197659
PMCID:
PMC5965872
AbstractArticlePDF–2.4M
11.
Cyclin-dependent kinase 5 mediates pleiotrophin-induced endothelial cell migration
Evgenia Lampropoulou, Ioanna Logoviti, Marina Koutsioumpa, Maria Hatziapostolou, Christos Polytarchou, Spyros S. Skandalis, Ulf Hellman, Manolis Fousteris, Sotirios Nikolaropoulos, Efrosini Choleva, Margarita Lamprou, Angeliki Skoura, Vasileios Megalooikonomou, Evangelia Papadimitriou
Sci Rep. 2018; 8: 5893. Published online 2018 Apr 12. doi: 10.1038/s41598-018-24326-x
PMCID:
PMC5897396
AbstractArticlePDF–3.3M
12.
Tumour exosomes from cells harbouring PTPRZ1–MET fusion contribute to a malignant phenotype and temozolomide chemoresistance in glioblastoma
A-L Zeng, W Yan, Y-W Liu, Z Wang, Q Hu, E Nie, X Zhou, R Li, X-F Wang, T Jiang, Y-P You
Oncogene. 2017 Sep 21; 36(38): 5369–5381. Published online 2017 May 15. doi: 10.1038/onc.2017.134
PMCID:
PMC5611480
AbstractArticlePDF–5.7M
13.
Molecular dissection of NRG1-ERBB4 signaling implicates PTPRZ1 as a potential schizophrenia susceptibility gene
JD Buxbaum, L Georgieva, JJ Young, C Plescia, Y Kajiwara, Y Jiang, V Moskvina, N Norton, T Peirce, H Williams, NJ Craddock, L Carroll, G Corfas, KL Davis, MJ Owen, S Harroch, T Sakurai, MC O’Donovan
Mol Psychiatry. Author manuscript; available in PMC 2017 Aug 23.
Published in final edited form as: Mol Psychiatry. 2008 Feb; 13(2): 162–172. Published online 2007 Apr 17. doi: 10.1038/sj.mp.4001991
PMCID:
PMC5567789
AbstractArticlePDF–780K
14.
Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions
Kyuho Han, Edwin E. Jeng, Gaelen T. Hess, David W. Morgens, Amy Li, Michael C. Bassik
Nat Biotechnol. Author manuscript; available in PMC 2017 Sep 20.
Published in final edited form as: Nat Biotechnol. 2017 May; 35(5): 463–474. Published online 2017 Mar 20. doi: 10.1038/nbt.3834
PMCID:
PMC5557292
AbstractArticlePDF–3.4M
15.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
16.
Targeting PTPRZ inhibits stem cell-like properties and tumorigenicity in glioblastoma cells
Akihiro Fujikawa, Hajime Sugawara, Taisaku Tanaka, Masahito Matsumoto, Kazuya Kuboyama, Ryoko Suzuki, Naomi Tanga, Atsuto Ogata, Makoto Masumura, Masaharu Noda
Sci Rep. 2017; 7: 5609. Published online 2017 Jul 17. doi: 10.1038/s41598-017-05931-8
PMCID:
PMC5514153
AbstractArticlePDF–8.0M
17.
Tumour-associated macrophages secrete pleiotrophin to promote PTPRZ1 signalling in glioblastoma stem cells for tumour growth
Yu Shi, Yi-Fang Ping, Wenchao Zhou, Zhi-Cheng He, Cong Chen, Bai-Shi-Jiao Bian, Lin Zhang, Lu Chen, Xun Lan, Xian-Chao Zhang, Kai Zhou, Qing Liu, Hua Long, Ti-Wei Fu, Xiao-Ning Zhang, Mian-Fu Cao, Zhi Huang, Xiaoguang Fang, Xiuxing Wang, Hua Feng, Xiao-Hong Yao, Shi-Cang Yu, You-Hong Cui, Xia Zhang, Jeremy N Rich, Shideng Bao, Xiu-Wu Bian
Nat Commun. 2017; 8: 15080. Published online 2017 Jun 1. doi: 10.1038/ncomms15080
PMCID:
PMC5461490
AbstractArticlePDF–4.5M
18.
Role of Chondroitin Sulfate (CS) Modification in the Regulation of Protein-tyrosine Phosphatase Receptor Type Z (PTPRZ) Activity: PLEIOTROPHIN-PTPRZ-A SIGNALING IS INVOLVED IN OLIGODENDROCYTE DIFFERENTIATION
Kazuya Kuboyama, Akihiro Fujikawa, Ryoko Suzuki, Naomi Tanga, Masaharu Noda
J Biol Chem. 2016 Aug 26; 291(35): 18117–18128. Published online 2016 Jul 21. doi: 10.1074/jbc.M116.742536
PMCID:
PMC5000061
AbstractArticlePDF–3.4M
19.
The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, Raphael J. Bruckner, Fana Gebreab, Melanie P. Gygi, John Szpyt, Stanley Tam, Gabriela Zarraga, Greg Colby, Kurt Baltier, Rui Dong, Virginia Guarani, Laura Pontano Vaites, Alban Ordureau, Ramin Rad, Brian K. Erickson, Martin Wühr, Joel Chick, Bo Zhai, Deepak Kolippakkam, Julian Mintseris, Robert A. Obar, Tim Harris, Spyros Artavanis-Tsakonas, Mathew E. Sowa, Pietro DeCamilli, Joao A. Paulo, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Cell. 2015 Jul 16; 162(2): 425–440. doi: 10.1016/j.cell.2015.06.043
PMCID:
PMC4617211
AbstractArticlePDF–2.2M
20.
Receptor protein tyrosine phosphatase beta/zeta is a functional binding partner for vascular endothelial growth factor
Marina Koutsioumpa, Evangelia Poimenidi, Evangelia Pantazaka, Christina Theodoropoulou, Angeliki Skoura, Vasileios Megalooikonomou, Nelly Kieffer, Jose Courty, Shuji Mizumoto, Kazuyuki Sugahara, Evangelia Papadimitriou
Mol Cancer. 2015; 14(1): 19. Published online 2015 Feb 3. doi: 10.1186/s12943-015-0287-3
PMCID:
PMC4323219
AbstractArticlePDF–3.5M

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