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Select item 107262521.

Structure and biochemical characterization of l-2-hydroxyglutarate dehydrogenase and its role in the pathogenesis of l-2-hydroxyglutaric aciduria

Jun Yang, Xingchen Chen, Shan Jin, Jianping Ding

J Biol Chem. 2024 Jan; 300(1): 105491. Published online 2023 Nov 22. doi: 10.1016/j.jbc.2023.105491

PMCID:: PMC10726252

Abstract Article PDF–3.2M

Select item 84688272.

Identification of GOLPH3 Partners in Drosophila Unveils Potential Novel Roles in Tumorigenesis and Neural Disorders

Stefano Sechi, Angela Karimpour-Ghahnavieh, Anna Frappaolo, Laura Di Francesco, Roberto Piergentili, Eugenia Schininà, Pier Paolo D’Avino, Maria Grazia Giansanti

Cells. 2021 Sep; 10(9): 2336. Published online 2021 Sep 6. doi: 10.3390/cells10092336

PMCID:: PMC8468827

Abstract Article PDF–4.1M

Select item 77047153.

The oncometabolite L-2-hydroxyglutarate is a common product of dipteran larval development

Nader H. Mahmoudzadeh, Alexander J. Fitt, Daniel B. Schwab, William E. Martenis, Lauren M. Nease, Charity G. Owings, Garrett J. Brinkley, Hongde Li, Jonathan A. Karty, Sunil Sudarshan, Richard W. Hardy, Armin P. Moczek, Christine J. Picard, Jason M. Tennessen

Insect Biochem Mol Biol. Author manuscript; available in PMC 2021 Dec 1.

Published in final edited form as: Insect Biochem Mol Biol. 2020 Dec; 127: 103493. Published online 2020 Nov 3. doi: 10.1016/j.ibmb.2020.103493

PMCID:: PMC7704715

Abstract Article PDF–1.4M

Select item 76421844.

Glial metabolic rewiring promotes axon regeneration and functional recovery in the central nervous system

Feng Li, Armin Sami, Harun N. Noristani, Kieran Slattery, Jingyun Qiu, Thomas Groves, Shuo Wang, Kelly Veerasammy, Yuki X. Chen, Jorge Morales, Paula Haynes, Amita Sehgal, Ye He, Shuxin Li, Yuanquan Song

Cell Metab. Author manuscript; available in PMC 2021 Nov 3.

Published in final edited form as: Cell Metab. 2020 Nov 3; 32(5): 767–785.e7. Published online 2020 Sep 16. doi: 10.1016/j.cmet.2020.08.015

PMCID:: PMC7642184

Abstract Article PDF–2.8M

Select item 69615785.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 68911006.

Mitochondrial stress causes neuronal dysfunction via an ATF4-dependent increase in L-2-hydroxyglutarate

Rachel J. Hunt, Lucy Granat, Gregory S. McElroy, Ramya Ranganathan, Navdeep S. Chandel, Joseph M. Bateman

J Cell Biol. 2019 Dec 2; 218(12): 4007–4016. Published online 2019 Oct 23. doi: 10.1083/jcb.201904148

PMCID:: PMC6891100

Abstract Article PDF–2.1M

Select item 61770127.

A Drosophila model of combined D-2- and L-2-hydroxyglutaric aciduria reveals a mechanism linking mitochondrial citrate export with oncometabolite accumulation

Hongde Li, Alexander J. Hurlburt, Jason M. Tennessen

Dis Model Mech. 2018 Sep 1; 11(9): dmm035337. Published online 2018 Sep 21. doi: 10.1242/dmm.035337

PMCID:: PMC6177012

Abstract Article

Select item 57078058.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 56890029.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 534099810.

A Luciferase-fragment Complementation Assay to Detect Lipid Droplet-associated Protein-Protein Interactions

Petra Kolkhof, Michael Werthebach, Anna van de Venn, Gereon Poschmann, Lili Chen, Michael Welte, Kai Stühler, Mathias Beller

Mol Cell Proteomics. 2017 Mar; 16(3): 329–345. Published online 2016 Dec 12. doi: 10.1074/mcp.M116.061499

PMCID:: PMC5340998

Abstract Article PDF–3.8M

Select item 530746411.

Drosophila larvae synthesize the putative oncometabolite L-2-hydroxyglutarate during normal developmental growth

Hongde Li, Geetanjali Chawla, Alexander J. Hurlburt, Maria C. Sterrett, Olga Zaslaver, James Cox, Jonathan A. Karty, Adam P. Rosebrock, Amy A. Caudy, Jason M. Tennessen

Proc Natl Acad Sci U S A. 2017 Feb 7; 114(6): 1353–1358. Published online 2017 Jan 23. doi: 10.1073/pnas.1614102114

PMCID:: PMC5307464

Abstract Article PDF–1.1M

Select item 452833012.

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders

Madeline A. Crosby, L. Sian Gramates, Gilberto dos Santos, Beverley B. Matthews, Susan E. St. Pierre, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, David B. Emmert, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1737–1749. Published online 2015 Jun 24. doi: 10.1534/g3.115.018937

PMCID:: PMC4528330

Abstract Article PDF–2.2M

Select item 452832913.

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data

Beverley B. Matthews, Gilberto dos Santos, Madeline A. Crosby, David B. Emmert, Susan E. St. Pierre, L. Sian Gramates, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, Victor Strelets, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1721–1736. Published online 2015 Jun 24. doi: 10.1534/g3.115.018929

PMCID:: PMC4528329

Abstract Article PDF–4.9M

Select item 439155514.

Identification of Genes That Promote or Inhibit Olfactory Memory Formation in Drosophila

Erica Walkinshaw, Yunchao Gai, Caitlin Farkas, Daniel Richter, Eric Nicholas, Krystyna Keleman, Ronald L. Davis

Genetics. 2015 Apr; 199(4): 1173–1182. Published online 2015 Feb 2. doi: 10.1534/genetics.114.173575

PMCID:: PMC4391555

Abstract Article PDF–1.1M

Select item 435288715.

The Release 6 reference sequence of the Drosophila melanogaster genome

Roger A. Hoskins, Joseph W. Carlson, Kenneth H. Wan, Soo Park, Ivonne Mendez, Samuel E. Galle, Benjamin W. Booth, Barret D. Pfeiffer, Reed A. George, Robert Svirskas, Martin Krzywinski, Jacqueline Schein, Maria Carmela Accardo, Elisabetta Damia, Giovanni Messina, María Méndez-Lago, Beatriz de Pablos, Olga V. Demakova, Evgeniya N. Andreyeva, Lidiya V. Boldyreva, Marco Marra, A. Bernardo Carvalho, Patrizio Dimitri, Alfredo Villasante, Igor F. Zhimulev, Gerald M. Rubin, Gary H. Karpen, Susan E. Celniker

Genome Res. 2015 Mar; 25(3): 445–458. doi: 10.1101/gr.185579.114

PMCID:: PMC4352887

Abstract Article PDF–1022K

Select item 427152716.

Phylostratigraphic Bias Creates Spurious Patterns of Genome Evolution

Bryan A. Moyers, Jianzhi Zhang

Mol Biol Evol. 2015 Jan 1; 32(1): 258–267. Published online 2014 Oct 13. doi: 10.1093/molbev/msu286

Correction in:: Mol Biol Evol. 2016 Nov; 33(11): 3031.

PMCID:: PMC4271527

Abstract Article PDF–618K

Select item 365152317.

Overexpression of Sir2 in the adult fat body is sufficient to extend lifespan of male and female Drosophila

Julia Hoffmann, Renja Romey, Christine Fink, Li Yong, Thomas Roeder

Aging (Albany NY) 2013 Apr; 5(4): 315–327. Published online 2013 Apr 29. doi: 10.18632/aging.100553

PMCID:: PMC3651523

Abstract Article PDF–2.0M

Select item 353067718.

High-fidelity promoter profiling reveals widespread alternative promoter usage and transposon-driven developmental gene expression

Philippe Batut, Alexander Dobin, Charles Plessy, Piero Carninci, Thomas R. Gingeras

Genome Res. 2013 Jan; 23(1): 169–180. doi: 10.1101/gr.139618.112

PMCID:: PMC3530677

Abstract Article PDF–1.5M

Select item 346946719.

The Many Landscapes of Recombination in Drosophila melanogaster

Josep M. Comeron, Ramesh Ratnappan, Samuel Bailin

PLoS Genet. 2012 Oct; 8(10): e1002905. Published online 2012 Oct 11. doi: 10.1371/journal.pgen.1002905

PMCID:: PMC3469467

Abstract Article PDF–1.6M

Select item 304044120.

A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionary-conserved pain gene

G. Gregory Neely, Andreas Hess, Michael Costigan, Alex C. Keene, Spyros Goulas, Michiel Langeslag, Robert S Griffin, Inna Belfer, Feng Dai, Shad Smith, Luda Diatchenko, Vaijayanti Gupta, Cui-ping Xia, Sabina Amann, Silke Kreitz, Cornelia Heindl-Erdmann, Susanne Wolz, Cindy V. Ly, Suchir Arora, Rinku Sarangi, Debasis Dan, Maria Novatchkova, Mark Rosenzweig, Dustin Gibson, Darwin Truong, Daniel Schramek, Tamara Zoranovic, Shane J. F. Cronin, Belinda Angjeli, Kay Brune, Georg Dietzl, William Maixner, Arabella Meixner, Winston Thomas, J. Andrew Pospisilik, Mattias Alenius, Michaela Kress, Sai Subramaniam, Paul A. Garrity, Hugo J. Bellen, Clifford J. Woolf, Josef M. Penninger

Cell. Author manuscript; available in PMC 2011 Nov 12.

Published in final edited form as: Cell. 2010 Nov 12; 143(4): 628–638. doi: 10.1016/j.cell.2010.09.047

PMCID:: PMC3040441

Abstract Article PDF–2.0M

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