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Select item 109451751.

Nuclear translocation of metabolic enzyme PKM2 participates in high glucose-promoted HCC metastasis by strengthening immunosuppressive environment

Jiali Qian, Chuxin Huang, Mimi Wang, Ying Liu, Yingying Zhao, Miao Li, Xi Zhang, Xiangyu Gao, Yawen Zhang, Yi Wang, Jinya Huang, Jiajun Li, Qiwen Zhou, Rui Liu, Xuanchun Wang, Jiefeng Cui, Yehong Yang

Redox Biol. 2024 May; 71: 103103. Published online 2024 Mar 4. doi: 10.1016/j.redox.2024.103103

PMCID:: PMC10945175

Abstract Article PDF–19M

Select item 107020132.

M-type pyruvate kinase 2 (PKM2) tetramerization alleviates the progression of right ventricle failure by regulating oxidative stress and mitochondrial dynamics

Lizhe Guo, Lu Wang, Gang Qin, Junjie Zhang, Jin Peng, Longyan Li, Xiang Chen, Dandan Wang, Jian Qiu, E. Wang

J Transl Med. 2023; 21: 888. Published online 2023 Dec 7. doi: 10.1186/s12967-023-04780-6

PMCID:: PMC10702013

Abstract Article PDF–5.0M

Select item 99362593.

Shikonin improves pulmonary vascular remodeling in monocrotaline‑induced pulmonary arterial hypertension via regulation of PKM2

Wenfeng Li, Wenjuan Chen, Hongyan Peng, Zhenghui Xiao, Jinqiao Liu, Yunhong Zeng, Ting Huang, Qingqing Song, Xun Wang, Yunbin Xiao

Mol Med Rep. 2023 Mar; 27(3): 60. Published online 2023 Feb 1. doi: 10.3892/mmr.2023.12947

PMCID:: PMC9936259

Abstract Article PDF–8.4M

Select item 99169474.

Pyruvate Kinase M2: A New Biomarker for the Early Detection of Diabetes-Induced Nephropathy

Yeon Su Park, Joo Hee Han, Jae Hyeon Park, Ji Soo Choi, Seung Hyeon Kim, Hyung Sik Kim

Int J Mol Sci. 2023 Feb; 24(3): 2683. Published online 2023 Jan 31. doi: 10.3390/ijms24032683

PMCID:: PMC9916947

Abstract Article PDF–3.0M

Select item 91015205.

Downregulation of miR-122-5p Activates Glycolysis via PKM2 in Kupffer Cells of Rat and Mouse Models of Non-Alcoholic Steatohepatitis

Yosuke Inomata, Jae-Won Oh, Kohei Taniguchi, Nobuhiko Sugito, Nao Kawaguchi, Fumitoshi Hirokawa, Sang-Woong Lee, Yukihiro Akao, Shinji Takai, Kwang-Pyo Kim, Kazuhisa Uchiyama

Int J Mol Sci. 2022 May; 23(9): 5230. Published online 2022 May 7. doi: 10.3390/ijms23095230

PMCID:: PMC9101520

Abstract Article PDF–4.4M

Select item 87952556.

Bile acids attenuate PKM2 pathway activation in proinflammatory microglia

Lorenzo Romero-Ramírez, Concepción García-Rama, Siyu Wu, Jörg Mey

Sci Rep. 2022; 12: 1459. Published online 2022 Jan 27. doi: 10.1038/s41598-022-05408-3

Correction in:: Sci Rep. 2022; 12: 3399.

PMCID:: PMC8795255

Abstract Article PDF–4.3M

Select item 67490437.

Effects of Tianshu Capsule on Spontaneously Hypertensive Rats as Revealed by ¹H-NMR-Based Metabolic Profiling

Jian Gao, Tieshan Wang, Chao Wang, Shuai Wang, Wei Wang, Di Ma, Yongbiao Li, Haibin Zhao, Jianxin Chen

Front Pharmacol. 2019; 10: 989. Published online 2019 Sep 11. doi: 10.3389/fphar.2019.00989

PMCID:: PMC6749043

Abstract Article PDF–2.0M

Select item 64873768.

Signal transducer and activator of transcription 3 promotes the Warburg effect possibly by inducing pyruvate kinase M2 phosphorylation in liver precancerous lesions

Yang-Hui Bi, Wen-Qi Han, Ruo-Fei Li, Yun-Jiao Wang, Zun-Shu Du, Xue-Jiang Wang, Ying Jiang

World J Gastroenterol. 2019 Apr 28; 25(16): 1936–1949. Published online 2019 Apr 28. doi: 10.3748/wjg.v25.i16.1936

PMCID:: PMC6487376

Abstract Article PDF–21M

Select item 58249589.

Identification and characterization of the BRI2 interactome in the brain

Filipa Martins, Ana M. Marafona, Cátia D. Pereira, Thorsten Müller, Christina Loosse, Katharina Kolbe, Odete A. B. da Cruz e Silva, Sandra Rebelo

Sci Rep. 2018; 8: 3548. Published online 2018 Feb 23. doi: 10.1038/s41598-018-21453-3

PMCID:: PMC5824958

Abstract Article PDF–1.7M

Select item 497239710.

E-cadherin interactome complexity and robustness resolved by quantitative proteomics

Zhenhuan Guo, Lisa J Neilson, Hang Zhong, Paul S Murray, Megha Vaman Rao, Sara Zanivan, Ronen Zaidel-Bar

Sci Signal. Author manuscript; available in PMC 2016 Aug 3.

Published in final edited form as: Sci Signal. 2014 Dec 2; 7(354): rs7. Published online 2014 Dec 2. doi: 10.1126/scisignal.2005473

PMCID:: PMC4972397

Abstract Article PDF–3.1M

Select item 461316911.

Nuclear translocation of PKM2 modulates astrocyte proliferation via p27 and β-catenin pathway after spinal cord injury

Jinlong Zhang, Guijuan Feng, Guofeng Bao, Guanhua Xu, Yuyu Sun, Weidong Li, Lingling Wang, Jiajia Chen, Huricha Jin, Zhiming Cui

Cell Cycle. 2015 Aug 18; 14(16): 2609–2618. Published online 2015 Jul 7. doi: 10.1080/15384101.2015.1064203

PMCID:: PMC4613169

Abstract Article PDF–1010K

Select item 425060312.

Gene expression profile in rat small intestinal allografts after cold preservation/reperfusion

Shu-Feng Wang, Qi Liang, Guo-Wei Li, Kun Gao

World J Gastroenterol. 2005 Feb 14; 11(6): 885–889. Published online 2005 Feb 14. doi: 10.3748/wjg.v11.i6.885

PMCID:: PMC4250603

Abstract Article PDF–479K

Select item 404071113.

Control of glioma cell death and differentiation by PKM2–Oct4 interaction

M Morfouace, L Lalier, L Oliver, M Cheray, C Pecqueur, P-F Cartron, F M Vallette

Cell Death Dis. 2014 Jan; 5(1): e1036. Published online 2014 Jan 30. doi: 10.1038/cddis.2013.561

PMCID:: PMC4040711

Abstract Article PDF–1.7M

Select item 395374714.

Interactome analysis of AMP-activated protein kinase (AMPK)-α1 and -β1 in INS-1 pancreatic beta-cells by affinity purification-mass spectrometry

Sungyoon Moon, Dohyun Han, Yikwon Kim, Jonghwa Jin, Won-Kyung Ho, Youngsoo Kim

Sci Rep. 2014; 4: 4376. Published online 2014 Mar 14. doi: 10.1038/srep04376

PMCID:: PMC3953747

Abstract Article PDF–1.4M

Select item 386171015.

SILAC-Based Proteomics of Human Primary Endothelial Cell Morphogenesis Unveils Tumor Angiogenic Markers

Sara Zanivan, Federica Maione, Marco Y. Hein, Juan Ramon Hernández-Fernaud, Pawel Ostasiewicz, Enrico Giraudo, Matthias Mann

Mol Cell Proteomics. 2013 Dec; 12(12): 3599–3611. Published online 2013 Aug 26. doi: 10.1074/mcp.M113.031344

PMCID:: PMC3861710

Abstract Article PDF–2.3M

Select item 381102216.

Isolation of Mammalian 26S Proteasomes and p97/VCP Complexes Using the Ubiquitin-like Domain from HHR23B Reveals Novel Proteasome-Associated Proteins

Henrike C. Besche, Wilhelm Haas, Steven P. Gygi, Alfred L. Goldberg

Biochemistry. Author manuscript; available in PMC 2013 Oct 29.

Published in final edited form as: Biochemistry. 2009 Mar 24; 48(11): 10.1021/bi802198q. doi: 10.1021/bi802198q

PMCID:: PMC3811022

Abstract Article PDF–3.7M

Select item 377350517.

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

Simona Principe, E. Ellen Jones, Yunee Kim, Ankit Sinha, Julius O. Nyalwidhe, Jasmin Brooks, O. John Semmes, Dean A. Troyer, Raymond S. Lance, Thomas Kislinger, Richard R. Drake

Proteomics. Author manuscript; available in PMC 2014 May 1.

Published in final edited form as: Proteomics. 2013 May; 13(0): 1667–1671. Published online 2013 Apr 23. doi: 10.1002/pmic.201200561

PMCID:: PMC3773505

Abstract Article PDF–630K

Select item 369664618.

Comparative Proteomic Analysis of Supportive and Unsupportive Extracellular Matrix Substrates for Human Embryonic Stem Cell Maintenance

Despina Soteriou, Banu Iskender, Adam Byron, Jonathan D. Humphries, Simon Borg-Bartolo, Marie-Claire Haddock, Melissa A. Baxter, David Knight, Martin J. Humphries, Susan J. Kimber

J Biol Chem. 2013 Jun 28; 288(26): 18716–18731. Published online 2013 May 8. doi: 10.1074/jbc.M113.463372