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Items: 1 to 20 of 21

1.
Rieske iron-sulfur protein induces FKBP12.6/RyR2 complex remodeling and subsequent pulmonary hypertension through NF-κB/cyclin D1 pathway
Lin Mei, Yun-Min Zheng, Tengyao Song, Vishal R. Yadav, Leroy C. Joseph, Lillian Truong, Sharath Kandhi, Margarida M. Barroso, Hiroshi Takeshima, Marc A. Judson, Yong-Xiao Wang
Nat Commun. 2020; 11: 3527. Published online 2020 Jul 15. doi: 10.1038/s41467-020-17314-1
PMCID:
PMC7363799
AbstractArticlePDF–1.5M
2.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
3.
High-Throughput Screens to Discover Small-Molecule Modulators of Ryanodine Receptor Calcium Release Channels
Robyn T. Rebbeck, Maram M. Essawy, Florentin R. Nitu, Benjamin D. Grant, Gregory D. Gillispie, David D. Thomas, Donald M. Bers, Razvan L. Cornea
SLAS Discov. Author manuscript; available in PMC 2018 Feb 1.
Published in final edited form as: SLAS Discov. 2017 Feb; 22(2): 176–186. Published online 2016 Oct 22. doi: 10.1177/1087057116674312
PMCID:
PMC5337111
AbstractArticlePDF–1.1M
4.
Total chemical synthesis, refolding, and crystallographic structure of fully active immunophilin calstabin 2 (FKBP12.6)
Marine Bacchi, Magali Jullian, Serena Sirigu, Benjamin Fould, Tiphaine Huet, Lisa Bruyand, Mathias Antoine, Laurent Vuillard, Luisa Ronga, Leonard M. G. Chavas, Olivier Nosjean, Gilles Ferry, Karine Puget, Jean A. Boutin
Protein Sci. 2016 Dec; 25(12): 2225–2242. Published online 2016 Oct 13. doi: 10.1002/pro.3051
PMCID:
PMC5119562
AbstractArticlePDF–3.3M
5.
Panorama of ancient metazoan macromolecular complexes
Cuihong Wan, Blake Borgeson, Sadhna Phanse, Fan Tu, Kevin Drew, Greg Clark, Xuejian Xiong, Olga Kagan, Julian Kwan, Alexandr Berzginov, Kyle Chessman, Swati Pal, Graham Cromar, Ophelia Papoulas, Zuyao Ni, Daniel R. Boutz, Snejana Stoilova, Pierre C. Havugimana, Xinghua Guo, Ramy H. Malty, Mihail Sarov, Jack Greenblatt, Mohan Babu, Brent Derry, Elisabeth Tillier, John B. Wallingford, John Parkinson, Edward M. Marcotte, Andrew Emili
Nature. Author manuscript; available in PMC 2016 Sep 26.
Published in final edited form as: Nature. 2015 Sep 17; 525(7569): 339–344. Published online 2015 Sep 7. doi: 10.1038/nature14877
PMCID:
PMC5036527
AbstractArticlePDF–4.7M
6.
A proteome-scale map of the human interactome network
Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal
Cell. Author manuscript; available in PMC 2015 Nov 20.
Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050
PMCID:
PMC4266588
AbstractArticlePDF–3.1M
7.
Sirolimus-FKBP12.6 Impairs Endothelial Barrier Function through PKCα Activation and Disruption of the p120-VE Cadherin Interaction
Anwer Habib, Vinit Karmali, Rohini Polavarapu, Hirokuni Akahori, Qi Cheng, Kim Pachura, Frank D. Kolodgie, Aloke V. Finn
Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2014 Oct 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2013 Oct; 33(10): 10.1161/ATVBAHA.113.301659. Published online 2013 Jul 25. doi: 10.1161/ATVBAHA.113.301659
PMCID:
PMC3827918
AbstractArticlePDF–2.6M
8.
Binding of RyR2 “Unzipping” Peptide in Cardiomyocytes Activates RyR2 and Reciprocally Inhibits Calmodulin Binding
Tetsuro Oda, Yi Yang, Florentin R. Nitu, Bengt Svensson, Xiyuan Lu, Bradley R. Fruen, Razvan L. Cornea, Donald M. Bers
Circ Res. Author manuscript; available in PMC 2014 Feb 1.
Published in final edited form as: Circ Res. 2013 Feb 1; 112(3): 487–497. Published online 2012 Dec 11. doi: 10.1161/CIRCRESAHA.111.300290
PMCID:
PMC3573756
AbstractArticlePDF–3.0M
9.
A negative screen for mutations in calstabin 1 and 2 genes in patients with dilated cardiomyopathy
Diogo G Biagi, José G Mill, Alfredo J Mansur, José E Krieger, Alexandre C Pereira
J Negat Results Biomed. 2012; 11: 4. Published online 2012 Jan 11. doi: 10.1186/1477-5751-11-4
PMCID:
PMC3268099
AbstractArticlePDF–223K
10.
Transgenic Analysis of the Role of FKBP12.6 in Cardiac Function and Intracellular Calcium Release
Ying Liu, Hanying Chen, Guangju Ji, Baiyan Li, Peter J. Mohler, Zhiming Zhu, Weidong Yong, Zhuang Chen, Xuehong Xu, Hongbo Xin, Weinian Shou
Assay Drug Dev Technol. 2011 Dec; 9(6): 620–627. doi: 10.1089/adt.2011.0411
PMCID:
PMC3232634
AbstractArticlePDF–528K
11.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
12.
Localization of the Dantrolene-binding Sequence near the FK506-binding Protein-binding Site in the Three-dimensional Structure of the Ryanodine Receptor
Ruiwu Wang, Xiaowei Zhong, Xing Meng, Andrea Koop, Xixi Tian, Peter P. Jones, Bradley R. Fruen, Terence Wagenknecht, Zheng Liu, S. R. Wayne Chen
J Biol Chem. 2011 Apr 8; 286(14): 12202–12212. Published online 2011 Jan 24. doi: 10.1074/jbc.M110.194316
PMCID:
PMC3069424
AbstractArticlePDF–3.6M
13.
Kinetics of FKBP12.6 binding to ryanodine receptors in permeabilized cardiac myocytes and effects on Ca sparks
Tao Guo, Razvan L. Cornea, Sabine Huke, Emmanuel Camors, Yi Yang, Eckard Picht, Bradley R. Fruen, Donald M. Bers
Circ Res. Author manuscript; available in PMC 2011 Jun 11.
Published in final edited form as: Circ Res. 2010 Jun 11; 106(11): 1743–1752. Published online 2010 Apr 29. doi: 10.1161/CIRCRESAHA.110.219816
PMCID:
PMC2895429
AbstractArticlePDF–857K
14.
Mapping the Ryanodine Receptor FK506-binding Protein Subunit Using Fluorescence Resonance Energy Transfer
Razvan L. Cornea, Florentin R. Nitu, Montserrat Samsó, David D. Thomas, Bradley R. Fruen
J Biol Chem. 2010 Jun 18; 285(25): 19219–19226. Published online 2010 Apr 19. doi: 10.1074/jbc.M109.066944
PMCID:
PMC2885200
AbstractArticlePDF–1.9M
15.
Removal of FKBP12.6 Does Not Alter the Conductance and Activation of the Cardiac Ryanodine Receptor or the Susceptibility to Stress-induced Ventricular Arrhythmias
Jianmin Xiao, Xixi Tian, Peter P. Jones, Jeff Bolstad, Huihui Kong, Ruiwu Wang, Lin Zhang, Henry J. Duff, Anne M. Gillis, Sidney Fleischer, Michael Kotlikoff, Julio A. Copello, S. R. Wayne Chen
J Biol Chem. Author manuscript; available in PMC 2009 Oct 12.
Published in final edited form as: J Biol Chem. 2007 Nov 30; 282(48): 34828–34838. Published online 2007 Oct 5. doi: 10.1074/jbc.M707423200
PMCID:
PMC2760432
AbstractArticlePDF–1.6M
16.
Genome-Wide Association Studies in an Isolated Founder Population from the Pacific Island of Kosrae
Jennifer K. Lowe, Julian B. Maller, Itsik Pe'er, Benjamin M. Neale, Jacqueline Salit, Eimear E. Kenny, Jessica L. Shea, Ralph Burkhardt, J. Gustav Smith, Weizhen Ji, Martha Noel, Jia Nee Foo, Maude L. Blundell, Vita Skilling, Laura Garcia, Marcia L. Sullivan, Heather E. Lee, Anna Labek, Hope Ferdowsian, Steven B. Auerbach, Richard P. Lifton, Christopher Newton-Cheh, Jan L. Breslow, Markus Stoffel, Mark J. Daly, David M. Altshuler, Jeffrey M. Friedman
PLoS Genet. 2009 Feb; 5(2): e1000365. Published online 2009 Feb 6. doi: 10.1371/journal.pgen.1000365
PMCID:
PMC2628735
AbstractArticlePDF–377K
17.
K201 (JTV519) suppresses spontaneous Ca2+ release and [3H]ryanodine binding to RyR2 irrespective of FKBP12.6 association
Donald J. Hunt, Peter P. Jones, Ruiwu Wang, Wenqian Chen, Jeff Bolstad, Keyun Chen, Yakhin Shimoni, S. R. Wayne Chen
Biochem J. 2007 Jun 15; 404(Pt 3): 431–438. Prepublished online 2007 Feb 22. Published online 2007 May 29. doi: 10.1042/BJ20070135
PMCID:
PMC1896290
AbstractArticlePDF–540K
18.
In situ modulation of the human cardiac ryanodine receptor (hRyR2) by FKBP12.6.
Christopher H George, Rina Sorathia, Benedicte M A Bertrand, F Anthony Lai
Biochem J. 2003 Mar 1; 370(Pt 2): 579–589. doi: 10.1042/BJ20021433
PMCID:
PMC1223191
SummaryPDF–364K
19.
Enhancing calstabin binding to ryanodine receptors improves cardiac and skeletal muscle function in heart failure
Xander H. T. Wehrens, Stephan E. Lehnart, Steven Reiken, Roel van der Nagel, Raymond Morales, Jie Sun, Zhenzhuang Cheng, Shi-Xiang Deng, Leon J. de Windt, Donald W. Landry, Andrew R. Marks
Proc Natl Acad Sci U S A. 2005 Jul 5; 102(27): 9607–9612. Published online 2005 Jun 22. doi: 10.1073/pnas.0500353102
PMCID:
PMC1172237
AbstractArticlePDF–437K
20.
The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)
Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504
Correction in:
Genome Res. 2006 Jun; 16(6): 804.
PMCID:
PMC528928
AbstractArticlePDF–140K

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