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Select item 113994411.

O-GlcNAcylation determines the function of the key O-GalNAc glycosyltransferase C1GalT1 in bladder cancer: O-GlcNAcylation governs pro-tumorigenic role of C1GalT1 in bladder cancer

Yazhuo Jiang, Jinpeng Wu, Feng Guan, Liang Liang, Yili Wang

Acta Biochim Biophys Sin (Shanghai) 2024 Aug 25; 56(8): 1108–1117. Published online 2024 Aug 8. doi: 10.3724/abbs.2024129

PMCID:: PMC11399441

Abstract Article PDF–2.0M

Select item 112579602.

Inhibition of the galactosyltransferase C1GALT1 reduces osteosarcoma cell proliferation by interfering with ERK signaling and cell cycle progression

Kentaro Watanabe, Keiji Tasaka, Hideto Ogata, Shota Kato, Hiroo Ueno, Katsutsugu Umeda, Tomoya Isobe, Yasuo Kubota, Masahiro Sekiguchi, Shunsuke Kimura, Aiko Sato-Otsubo, Mitsuteru Hiwatari, Tetsuo Ushiku, Motohiro Kato, Akira Oka, Satoru Miyano, Seishi Ogawa, Junko Takita

Cancer Gene Ther. 2024; 31(7): 1049–1059. Published online 2024 Apr 15. doi: 10.1038/s41417-024-00773-9

PMCID:: PMC11257960

Abstract Article PDF–8.0M

Select item 110455953.

High core 1β1,3-galactosyltransferase 1 expression is associated with poor prognosis and promotes cellular radioresistance in lung adenocarcinoma

Yong Chen, Yanyan Ji, Lin Shen, Ying Li, Yue Ren, Hongcan Shi, Yue Li, Yunjiang Wu

J Cancer Res Clin Oncol. 2024; 150(4): 214. Published online 2024 Apr 25. doi: 10.1007/s00432-024-05745-y

PMCID:: PMC11045595

Abstract Article PDF–4.9M

Select item 103204744.

Truncation of GalNAc-type O-glycans Suppresses CD44-mediated Osteoclastogenesis and Bone Metastasis in Breast Cancer

Neng-Yu Lin, Jian-Jr Lee, Syue-Ting Chen, Jung-An Lin, Chia-Hsuan Lin, Hsuan-Yu Lin, Yong-Han Su, Cheng-Chang Chen, Mei-Chun Lin, Ching-Ying Kuo, Min-Chuan Huang

Mol Cancer Res. 2023 Jul 5; 21(7): 664–674. Published online 2023 Apr 11. doi: 10.1158/1541-7786.MCR-22-0907

PMCID:: PMC10320474

Abstract Article PDF–15M

Select item 100339375.

Assessment of community efforts to advance network-based prediction of protein–protein interactions

Xu-Wen Wang, Lorenzo Madeddu, Kerstin Spirohn, Leonardo Martini, Adriano Fazzone, Luca Becchetti, Thomas P. Wytock, István A. Kovács, Olivér M. Balogh, Bettina Benczik, Mátyás Pétervári, Bence Ágg, Péter Ferdinandy, Loan Vulliard, Jörg Menche, Stefania Colonnese, Manuela Petti, Gaetano Scarano, Francesca Cuomo, Tong Hao, Florent Laval, Luc Willems, Jean-Claude Twizere, Marc Vidal, Michael A. Calderwood, Enrico Petrillo, Albert-László Barabási, Edwin K. Silverman, Joseph Loscalzo, Paola Velardi, Yang-Yu Liu

Nat Commun. 2023; 14: 1582. Published online 2023 Mar 22. doi: 10.1038/s41467-023-37079-7

PMCID:: PMC10033937

Abstract Article PDF–1.5M

Select item 93061736.

Dysregulation and prometastatic function of glycosyltransferase C1GALT1 modulated by cHP1BP3/ miR-1-3p axis in bladder cancer

Zengqi Tan, Yazhuo Jiang, Liang Liang, Jinpeng Wu, Lin Cao, Xiaoman Zhou, Zhihui Song, Zhenyu Ye, Ziyan Zhao, Hui Feng, Zewen Dong, Shuai Lin, Zhangjian Zhou, Yili Wang, Xiang Li, Feng Guan

J Exp Clin Cancer Res. 2022; 41: 228. Published online 2022 Jul 21. doi: 10.1186/s13046-022-02438-7

PMCID:: PMC9306173

Abstract Article PDF–16M

Select item 92316237.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 84212678.

GOLPH3 and GOLPH3L are broad-spectrum COPI adaptors for sorting into intra-Golgi transport vesicles

Lawrence G. Welch, Sew-Yeu Peak-Chew, Farida Begum, Tim J. Stevens, Sean Munro

J Cell Biol. 2021 Oct 4; 220(10): e202106115. Published online 2021 Sep 2. doi: 10.1083/jcb.202106115

PMCID:: PMC8421267

Abstract Article PDF–5.4M

Select item 81650309.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 792018510.

Interaction between GALNT12 and C1GALT1 Associates with Galactose-Deficient IgA1 and IgA Nephropathy

Yan-Na Wang, Xu-Jie Zhou, Pei Chen, Gui-Zhen Yu, Xue Zhang, Ping Hou, Li-Jun Liu, Su-Fang Shi, Ji-Cheng Lv, Hong Zhang

J Am Soc Nephrol. 2021 Mar; 32(3): 545–552. Published online 2021 Feb 16. doi: 10.1681/ASN.2020060823

PMCID:: PMC7920185

Abstract Article

Select item 789233811.

C1GALT1 high expression is associated with poor survival of patients with pancreatic ductal adenocarcinoma and promotes cell invasiveness through integrin α_v

Ting-Chun Kuo, Ming-Hsun Wu, Shih-Hung Yang, Syue-Ting Chen, Tzu-Wen Hsu, Jie-Yang Jhuang, Ying-Yu Liao, Yu-Wen Tien, Min-Chuan Huang

Oncogene. 2021; 40(7): 1242–1254. Published online 2021 Jan 8. doi: 10.1038/s41388-020-01594-4

PMCID:: PMC7892338

Abstract Article PDF–4.4M

Select item 768105312.

Elevated miR‐124‐3p in the aging colon disrupts mucus barrier and increases susceptibility to colitis by targeting T‐synthase

Li Huang, Ting‐yi Sun, Liang‐jun Hu, Shi‐long Hu, Hai‐mei Sun, Fu‐qian Zhao, Bo Wu, Shu Yang, Feng‐qing Ji, De‐shan Zhou

Aging Cell. 2020 Nov; 19(11): e13252. Published online 2020 Oct 11. doi: 10.1111/acel.13252

PMCID:: PMC7681053

Abstract Article PDF–3.1M

Select item 716998313.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 709888414.

C1GALT1 is associated with poor survival and promotes soluble Ephrin A1-mediated cell migration through activation of EPHA2 in gastric cancer

Po-Chu Lee, Syue-Ting Chen, Ting-Chun Kuo, Tzu-Chi Lin, Mei-Chun Lin, John Huang, Ji-Shiang Hung, Chia-Lang Hsu, Hsueh-Fen Juan, Po-Huang Lee, Min-Chuan Huang

Oncogene. 2020; 39(13): 2724–2740. Published online 2020 Jan 31. doi: 10.1038/s41388-020-1178-7

PMCID:: PMC7098884

Abstract Article PDF–2.8M

Select item 652631015.

A CRISPR Screen Using Subtilase Cytotoxin Identifies SLC39A9 as a Glycan-Regulating Factor

Toshiyuki Yamaji, Hisatoshi Hanamatsu, Tsuyoshi Sekizuka, Makoto Kuroda, Norimasa Iwasaki, Makoto Ohnishi, Jun-ichi Furukawa, Kinnosuke Yahiro, Kentaro Hanada

iScience. 2019 May 31; 15: 407–420. Published online 2019 May 8. doi: 10.1016/j.isci.2019.05.005

PMCID:: PMC6526310

Abstract Article PDF–11M

Select item 620232416.

C1GALT1 predicts poor prognosis and is a potential therapeutic target in head and neck cancer

Mei-Chun Lin, Pin-Hui Chien, Hsin-Yi Wu, Syue-Ting Chen, Hsueh-Fen Juan, Pei-Jen Lou, Min-Chuan Huang

Oncogene. 2018; 37(43): 5780–5793. Published online 2018 Jun 21. doi: 10.1038/s41388-018-0375-0

PMCID:: PMC6202324

Abstract Article PDF–1.7M

Select item 616668217.

Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei

Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck

Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924

PMCID:: PMC6166682

Abstract Article PDF–3.8M

Select item 609720818.

Differential expression of Cosmc, T-synthase and mucins in Tn-positive colorectal cancers

Xiaodong Sun, Tongzhong Ju, Richard D. Cummings

BMC Cancer. 2018; 18: 827. Published online 2018 Aug 16. doi: 10.1186/s12885-018-4708-8

PMCID:: PMC6097208

Abstract Article PDF–7.5M

Select item 603266019.

T-Synthase Deficiency Enhances Oncogenic Features in Human Colorectal Cancer Cells via Activation of Epithelial-Mesenchymal Transition

Xichen Dong, Yuliang Jiang, Jian Liu, Zhe Liu, Tianbo Gao, Guangyu An, Tao Wen

Biomed Res Int. 2018; 2018: 9532389. Published online 2018 Jun 21. doi: 10.1155/2018/9532389

PMCID:: PMC6032660

Abstract Article PDF–1.7M

Select item 553161120.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

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