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Items: 1 to 20 of 205

1.
Drug-induced hepatotoxicity and association with slow acetylation variants NAT2*5 and NAT2*6 in Cameroonian patients with tuberculosis and HIV co-infection
Frederick Nchang Cho, Eric A. Achidi, Jude Eteneneng Enoh, Srinivas Reddy Pallerla, Le Thi Kieu Linh, Hoang Van Tong, Joseph Kamgno, Véronique Beng Penlap, Ayola Akim Adegnika, Jean-Bernard Lekana-Douki, Marielle Karine Bouyou-Akotet, Gauthier Mesia Kahunu, Gaston Tona Lutete, Mathew Bates, John Tembo, Linzy Elton, Timothy D McHugh, Martin P Grobusch, Alimuddin Zumla, Francine Ntoumi, Thirumalaisamy P. Velavan
BMC Infect Dis. 2024; 24: 759. Published online 2024 Jul 31. doi: 10.1186/s12879-024-09638-w
PMCID:
PMC11293078
AbstractArticlePDF–1.5M
2.
Induction of Glucose Production by Heterocyclic Amines is Dependent on N-acetyltransferase 2 Genetic Polymorphism in Cryopreserved Human Hepatocytes
Kennedy M. Walls, Kyung U. Hong, David W. Hein
Toxicol Lett. Author manuscript; available in PMC 2024 Jul 7.
Published in final edited form as: Toxicol Lett. 2023 Jul 1; 383: 192–195. Published online 2023 Jul 7. doi: 10.1016/j.toxlet.2023.07.002
PMCID:
PMC10528954
AbstractArticlePDF–409K
3.
N-Acetyltransferase 2 Haplotype Modifies Risks for Both Dyslipidemia and Urinary Bladder Cancer
Kyung U. Hong, David W. Hein
Pharmacogenet Genomics. Author manuscript; available in PMC 2024 Aug 1.
Published in final edited form as: Pharmacogenet Genomics. 2023 Aug 1; 33(6): 136–137. Published online 2023 May 29. doi: 10.1097/FPC.0000000000000500
PMCID:
PMC10524719
AbstractArticlePDF–293K
4.
The impact of IDH and NAT2 gene polymorphisms in acute myeloid leukemia risk and overall survival in an Arab population: A case-control study
Sohaib M. Al-Khatib, Obada Ababneh, Hassann Abushukair, Nour Abdo, Laith N. Al-Eitan
PLoS One. 2023; 18(7): e0289014. Published online 2023 Jul 21. doi: 10.1371/journal.pone.0289014
PMCID:
PMC10361469
AbstractArticlePDF–988K
5.
N-acetyltransferase 2 genetic polymorphism modifies genotoxic and oxidative damage from new psychoactive substances
Raúl A. Salazar-González, Mark A. Doll, David W Hein
Arch Toxicol. Author manuscript; available in PMC 2024 Jan 1.
Published in final edited form as: Arch Toxicol. 2023 Jan; 97(1): 189–199. Published online 2022 Sep 23. doi: 10.1007/s00204-022-03383-2
PMCID:
PMC10187882
AbstractArticlePDF–956K
6.
NAT2 global landscape: Genetic diversity and acetylation statuses from a systematic review
Jorge E. Gutiérrez-Virgen, Maricela Piña-Pozas, Esther A. Hernández-Tobías, Lucia Taja-Chayeb, Ma. de Lourdes López-González, Marco A. Meraz-Ríos, Rocío Gómez
PLoS One. 2023; 18(4): e0283726. Published online 2023 Apr 6. doi: 10.1371/journal.pone.0283726
PMCID:
PMC10079069
AbstractArticlePDF–2.5M
7.
Pharmacogenetic testing for NAT2 genotypes in a Tanzanian population across the lifespan to guide future personalized isoniazid dosing
Maano V. Masiphephethu, Margaretha Sariko, Thomas Walongo, Athanasia Maro, Dorcus Mduma, Jean Gratz, Mohammad Alshaer, Charles A. Peloquin, Estomih Mduma, Stellah G. Mpagama, Tania Thomas, Eric R. Houpt, Afsatou Traore, Pascal Bessong, Scott K. Heysell, Darwin J. Operario
Tuberculosis (Edinb) Author manuscript; available in PMC 2023 Jan 29.
Published in final edited form as: Tuberculosis (Edinb). 2022 Sep; 136: 102246. Published online 2022 Aug 8. doi: 10.1016/j.tube.2022.102246
PMCID:
PMC9884397
AbstractArticlePDF–864K
8.
Transcriptional Regulation of Human Arylamine N-Acetyltransferase 2 Gene by Glucose and Insulin in Liver Cancer Cell Lines
Kyung U Hong, Raúl A Salazar-González, Kennedy M Walls, David W Hein
Toxicol Sci. 2022 Dec; 190(2): 158–172. Published online 2022 Sep 26. doi: 10.1093/toxsci/kfac103
PMCID:
PMC9702998
AbstractArticlePDF–922K
9.
Influence of NAT2 Genotype and Maturation on Isoniazid Exposure in Low-Birth-Weight and Preterm Infants With or Without Human Immunodeficiency Virus (HIV) Exposure
Agathe Béranger, Adrie Bekker, Belén P Solans, Mark F Cotton, Mark Mirochnick, Avy Violari, Jiajia Wang, Mae Cababasay, Lubbe Wiesner, Renee Browning, Jack Moye, Edmund V Capparelli, Radojka M Savic
Clin Infect Dis. 2022 Sep 15; 75(6): 1037–1045. Published online 2022 Feb 4. doi: 10.1093/cid/ciac001
PMCID:
PMC9522418
AbstractArticlePDF–8.5M
10.
NAT2 and CYP2E1 polymorphisms and antituberculosis drug‐induced hepatotoxicity in Peruvian patients
Luis Jaramillo‐Valverde, Kelly S. Levano, David D. Tarazona, Silvia Capristano, Roberto Zegarra‐Chapoñan, Cesar Sanchez, Velia M. Yufra‐Picardo, Eduardo Tarazona‐Santos, Cesar Ugarte‐Gil, Heinner Guio
Mol Genet Genomic Med. 2022 Aug; 10(8): e1987. Published online 2022 Jun 24. doi: 10.1002/mgg3.1987
PMCID:
PMC9356556
AbstractArticlePDF–685K
11.
Expression of Arylamine N-Acetyltransferase 2 Activity in Immortalized Human Bronchial Epithelial Cells
James T.F. Wise, Raúl A. Salazar-González, Mariam R. Habil, Mark A. Doll, David W. Hein
Toxicol Appl Pharmacol. Author manuscript; available in PMC 2023 May 1.
Published in final edited form as: Toxicol Appl Pharmacol. 2022 May 1; 442: 115993. Published online 2022 Mar 27. doi: 10.1016/j.taap.2022.115993
PMCID:
PMC9112076
AbstractArticlePDF–1.3M
12.
Modifying Effect of Smoking on GSTM1 and NAT2 in Relation to the Risk of Bladder Cancer in Mongolian Population: A Case-Control Study
Shiirevnyamba Avirmed, Yerkhanat Khuanbai, Amarsaikhan Sanjaajamts, Baasansuren Selenge, Bayan-Undur Dagvadorj, Makoto Ohashi
Asian Pac J Cancer Prev. 2021 Aug; 22(8): 2479–2485. doi: 10.31557/APJCP.2021.22.8.2479
PMCID:
PMC8629459
AbstractArticlePDF–302K
13.
Allelic and genotypic frequencies of NAT2, CYP2E1, and AADAC genes in a cohort of Peruvian tuberculosis patients
Kelly S. Levano, Luis Jaramillo‐Valverde, David D. Tarazona, Cesar Sanchez, Silvia Capristano, Tania Vásquez‐Loarte, Lely Solari, Alberto Mendoza‐Ticona, Alonso Soto, Christian Rojas, Roberto Zegarra‐Chapoñan, Heinner Guio
Mol Genet Genomic Med. 2021 Oct; 9(10): e1764. Published online 2021 Sep 12. doi: 10.1002/mgg3.1764
PMCID:
PMC8580101
AbstractArticlePDF–552K
14.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
15.
Evaluation of Genetic Polymorphisms of N-acetyltransferase 2 and Relation with Chronic Myeloid Leukemia
Entesar M Tebien, Hiba B Khalil, Jeremy Mills, Abozer Y. Elderdery
Asian Pac J Cancer Prev. 2020 Dec; 21(12): 3711–3717. doi: 10.31557/APJCP.2020.21.12.3711
PMCID:
PMC8046315
AbstractArticlePDF–397K
16.
Unexpected Acetylation of Endogenous Aliphatic Amines by Arylamine N‐Acetyltransferase NAT2
Dr. Louis P. Conway, Dr. Veronica Rendo, M. Sc. Mário S. P. Correia, Prof. Dr. Ingvar A. Bergdahl, Prof. Dr. Tobias Sjöblom, Prof. Dr. Daniel Globisch
Angew Chem Int Ed Engl. 2020 Aug 17; 59(34): 14342–14346. Published online 2020 Jul 8. doi: 10.1002/anie.202005915
PMCID:
PMC7497018
AbstractArticlePDF–2.0M
17.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
18.
N-acetyltransferase 2 acetylator genotype-dependent N-acetylation of 4-aminobiphenyl in cryopreserved human hepatocytes
Mariam R. Habil, Mark A. Doll, David W. Hein
Pharmacogenet Genomics. Author manuscript; available in PMC 2021 Apr 1.
Published in final edited form as: Pharmacogenet Genomics. 2020 Apr; 30(3): 61–65. doi: 10.1097/FPC.0000000000000394
PMCID:
PMC7060095
AbstractArticlePDF–219K
19.
The association between NAT2 acetylator status and adverse drug reactions of sulfasalazine: a systematic review and meta-analysis
Jeong Yee, So Min Kim, Ji Min Han, Nari Lee, Ha Young Yoon, Hye Sun Gwak
Sci Rep. 2020; 10: 3658. Published online 2020 Feb 27. doi: 10.1038/s41598-020-60467-8
PMCID:
PMC7046788
AbstractArticlePDF–2.4M
20.
Role of Human N-Acetyltransferase 2 Genetic Polymorphism on Aromatic Amine Carcinogen-induced DNA Damage and Mutagenicity in a Chinese Hamster Ovary Cell Mutation Assay
Kristin J. Baldauf, Raúl A. Salazar-González, Mark A. Doll, William M. Pierce, Jr., J. Christopher States, David W. Hein
Environ Mol Mutagen. Author manuscript; available in PMC 2021 Feb 1.
Published in final edited form as: Environ Mol Mutagen. 2020 Feb; 61(2): 235–245. Published online 2019 Sep 30. doi: 10.1002/em.22331
PMCID:
PMC7017392
AbstractArticlePDF–604K

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