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Items: 1 to 20 of 121

1.
Neurodevelopmental defects in a mouse model of O-GlcNAc transferase intellectual disability
Florence Authier, Nina Ondruskova, Andrew T. Ferenbach, Alison D. McNeilly, Daan M. F. van Aalten
Dis Model Mech. 2024 Apr 1; 17(4): dmm050671. Published online 2024 Apr 25. doi: 10.1242/dmm.050671
PMCID:
PMC11095632
AbstractArticle
2.
Paternal DDT exposure induces sex-specific programming of fetal growth, placenta development and offspring’s health phenotypes in a mouse model
Elaine Chen, Raquel Santana da Cruz, Aallya Nascimento, Meghali Joshi, Duane Gischewski Pereira, Odalys Dominguez, Gabriela Fernandes, Megan Smith, Sara P. C. Paiva, Sonia de Assis
Sci Rep. 2024; 14: 7567. Published online 2024 Mar 30. doi: 10.1038/s41598-024-58176-7
PMCID:
PMC10981700
AbstractArticlePDF–3.0M
3.
Cardioprotective O-GlcNAc signaling is elevated in murine female hearts via enhanced O-GlcNAc transferase activity
Bhargavi Narayanan, Prithvi Sinha, Roger Henry, Russell A. Reeves, Nazareno Paolocci, Mark J. Kohr, Natasha E. Zachara
J Biol Chem. 2023 Dec; 299(12): 105447. Published online 2023 Nov 8. doi: 10.1016/j.jbc.2023.105447
PMCID:
PMC10711226
AbstractArticlePDF–2.4M
4.
Nutritional and metabolic control of germ cell fate through O‐GlcNAc regulation
Yohei Hayashi, Yukiko Tando, Yumi Ito‐Matsuoka, Kaho Ikuta, Asuka Takehara, Katsutaro Morino, Hiroshi Maegawa, Yasuhisa Matsui
EMBO Rep. 2023 Nov; 24(11): e56845. Published online 2023 Oct 16. doi: 10.15252/embr.202356845
PMCID:
PMC10626443
AbstractArticlePDF–2.9M
5.
KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility
Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao
Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5
PMCID:
PMC10307852
AbstractArticlePDF–8.8M
6.
Ogt-mediated O-GlcNAcylation inhibits astrocytes activation through modulating NF-κB signaling pathway
Xiaoxue Dong, Liqi Shu, Jinyu Zhang, Xu Yang, Xuejun Cheng, Xingsen Zhao, Wenzheng Qu, Qiang Zhu, Yikai Shou, Guoping Peng, Binggui Sun, Wen Yi, Qiang Shu, Xuekun Li
J Neuroinflammation. 2023; 20: 146. Published online 2023 Jun 22. doi: 10.1186/s12974-023-02824-8
PMCID:
PMC10286367
AbstractArticlePDF–3.4M
7.
Deletion of Smooth Muscle O-GlcNAc Transferase Prevents Development of Atherosclerosis in Western Diet-Fed Hyperglycemic ApoE-/- Mice In Vivo
Saugat Khanal, Neha Bhavnani, Amy Mathias, Jason Lallo, Shreya Gupta, Vahagn Ohanyan, Jessica M. Ferrell, Priya Raman
Int J Mol Sci. 2023 May; 24(9): 7899. Published online 2023 Apr 26. doi: 10.3390/ijms24097899
PMCID:
PMC10178779
AbstractArticlePDF–11M
8.
O-GlcNAc transferase in astrocytes modulates depression-related stress susceptibility through glutamatergic synaptic transmission
Jun Fan, Fang Guo, Ran Mo, Liang-Yu Chen, Jia-Wen Mo, Cheng-Lin Lu, Jing Ren, Qiu-Ling Zhong, Xiao-Jing Kuang, You-Lu Wen, Ting-Ting Gu, Jin-Ming Liu, Shu-Ji Li, Ying-Ying Fang, Cunyou Zhao, Tian-Ming Gao, Xiong Cao
J Clin Invest. 2023 Apr 3; 133(7): e160016. Published online 2023 Apr 3. doi: 10.1172/JCI160016
PMCID:
PMC10065078
AbstractArticlePDF–4.3M
9.
O-GlcNAc glycosylation orchestrates fate decision and niche function of bone marrow stromal progenitors
Zengdi Zhang, Zan Huang, Mohamed Awad, Mohammed Elsalanty, James Cray, Lauren E Ball, Jason C Maynard, Alma L Burlingame, Hu Zeng, Kim C Mansky, Hai-Bin Ruan
eLife. 2023; 12: e85464. Published online 2023 Mar 2. doi: 10.7554/eLife.85464
PMCID:
PMC10032655
AbstractArticlePDF–15M
10.
Overexpression of Pdx1, reduction of p53, or deletion of CHOP attenuates pancreas hypoplasia in mice with pancreas-specific O-GlcNAc transferase deletion
Alicia Wong, Samantha Pritchard, Mackenzie Moore, Brian Akhaphong, Nandini Avula, Megan Beetch, Yoshio Fujitani, Emilyn U. Alejandro
J Biol Chem. 2023 Feb; 299(2): 102878. Published online 2023 Jan 6. doi: 10.1016/j.jbc.2023.102878
PMCID:
PMC9932656
AbstractArticlePDF–3.4M
11.
O-GlcNAcylation of SIRT1 Protects against Cold Stress-Induced Skeletal Muscle Damage via Amelioration of Mitochondrial Homeostasis
Yu Cao, Meng Zhang, Ye Li, Jingjing Lu, Wanhui Zhou, Xiaoshuang Li, Hao Shi, Bin Xu, Shize Li
Int J Mol Sci. 2022 Dec; 23(23): 14520. Published online 2022 Nov 22. doi: 10.3390/ijms232314520
PMCID:
PMC9737900
AbstractArticlePDF–5.1M
12.
Ventromedial hypothalamic OGT drives adipose tissue lipolysis and curbs obesity
Qi Wang, Bichen Zhang, Bernardo Stutz, Zhong-Wu Liu, Tamas L. Horvath, Xiaoyong Yang
Sci Adv. 2022 Sep; 8(35): eabn8092. Published online 2022 Aug 31. doi: 10.1126/sciadv.abn8092
PMCID:
PMC9432828
AbstractArticlePDF–8.2M
13.
O-GlcNAcylation promotes cerebellum development and medulloblastoma oncogenesis via SHH signaling
Liping Chen, Ying Li, Zhihong Song, Saisai Xue, Fengjiao Liu, Xin Chang, Yan Wu, Xiaotao Duan, Haitao Wu
Proc Natl Acad Sci U S A. 2022 Aug 23; 119(34): e2202821119. Published online 2022 Aug 15. doi: 10.1073/pnas.2202821119
PMCID:
PMC9407465
AbstractArticlePDF–3.2M
14.
An OGT-STAT5 Axis in Regulatory T Cells Controls Energy and Iron Metabolism
Zengdi Zhang, Oscar C. Salgado, Bing Liu, Zahra Moazzami, Kristin A. Hogquist, Michael A. Farrar, Hai-Bin Ruan
Front Immunol. 2022; 13: 874863. Published online 2022 Jul 8. doi: 10.3389/fimmu.2022.874863
PMCID:
PMC9304952
AbstractArticlePDF–8.3M
15.
Epithelial STAT6 O-GlcNAcylation drives a concerted anti-helminth alarmin response dependent on tuft cell hyperplasia and Gasdermin C
Ming Zhao, Kaiqun Ren, Xiwen Xiong, Yue Xin, Yujie Zou, Jason C. Maynard, Angela Kim, Alexander P. Battist, Navya Koneripalli, Yusu Wang, Qianyue Chen, Ruyue Xin, Chenyan Yang, Rong Huang, Jiahui Yu, Zan Huang, Zengdi Zhang, Haiguang Wang, Daoyuan Wang, Yihui Xiao, Oscar C. Salgado, Nicholas N. Jarjour, Kristin A Hogquist, Xavier S. Revelo, Alma L. Burlingame, Xiang Gao, Jakob von Moltke, Zhaoyu Lin, Hai-Bin Ruan
Immunity. Author manuscript; available in PMC 2023 Apr 12.
Published in final edited form as: Immunity. 2022 Apr 12; 55(4): 623–638.e5. Published online 2022 Apr 5. doi: 10.1016/j.immuni.2022.03.009
Correction in:
Immunity. 2022 Jul 12; 55(7): 1327.
PMCID:
PMC9109499
AbstractArticlePDF–3.3M
16.
Glycaemia and body weight are regulated by sodium-glucose cotransporter 1 (SGLT1) expression via O-GlcNAcylation in the intestine
Kimihiro Nishimura, Yukihiro Fujita, Shogo Ida, Tsuyoshi Yanagimachi, Natsuko Ohashi, Kiyoto Nishi, Atsushi Nishida, Yasumasa Iwasaki, Katsutaro Morino, Satoshi Ugi, Eiichiro Nishi, Akira Andoh, Hiroshi Maegawa
Mol Metab. 2022 May; 59: 101458. Published online 2022 Feb 19. doi: 10.1016/j.molmet.2022.101458
PMCID:
PMC8902621
AbstractArticlePDF–4.5M
17.
Pancreatic β-Cell O-GlcNAc Transferase Overexpression Increases Susceptibility to Metabolic Stressors in Female Mice
Ramkumar Mohan, Seokwon Jo, Elina Da Sol Chung, Eunice Oribamise, Amber Lockridge, Juan E. Abrahante-Lloréns, Hai-Bin Ruan, Xiao-Yong Yang, Emilyn U. Alejandro
Cells. 2021 Oct; 10(10): 2801. Published online 2021 Oct 19. doi: 10.3390/cells10102801
PMCID:
PMC8534823
AbstractArticlePDF–3.9M
18.
Analysis of Gene Expression Patterns of Epigenetic Enzymes Dnmt3a, Tet1 and Ogt in Murine Chondrogenic Models
Judit Vágó, Katalin Kiss, Edina Karanyicz, Roland Takács, Csaba Matta, László Ducza, Tibor A. Rauch, Róza Zákány
Cells. 2021 Oct; 10(10): 2678. Published online 2021 Oct 6. doi: 10.3390/cells10102678
PMCID:
PMC8534543
AbstractArticlePDF–4.9M
19.
Silencing of O-linked N-acetylglucosamine transferase ameliorates hypercalcemia-induced neurotoxicity in renal failure by regulating EZH2/KLF2/CXCL1 axis
Yaochen Cao, Xin Chen, Hongming Sun
Cell Death Dis. 2021 Sep; 12(9): 819. Published online 2021 Aug 30. doi: 10.1038/s41419-021-04022-x
PMCID:
PMC8405781
AbstractArticlePDF–2.2M
20.
Skeletal Muscle O-GlcNAc Transferase Action on Global Metabolism Is Partially Mediated Through Interleukin-15
Morgan D. Zumbaugh, Con-Ning Yen, Jocelyn S. Bodmer, Hao Shi, David E. Gerrard
Front Physiol. 2021; 12: 682052. Published online 2021 Jul 13. doi: 10.3389/fphys.2021.682052
PMCID:
PMC8313823
AbstractArticlePDF–2.1M

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