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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 106219212.

Precision pharmacological reversal of strain-specific diet-induced metabolic syndrome in mice informed by epigenetic and transcriptional regulation

Phillip Wulfridge, Adam Davidovich, Anna C. Salvador, Gabrielle C. Manno, Rakel Tryggvadottir, Adrian Idrizi, M. Nazmul Huda, Brian J. Bennett, L. Garry Adams, Kasper D. Hansen, David W. Threadgill, Andrew P. Feinberg

PLoS Genet. 2023 Oct; 19(10): e1010997. Published online 2023 Oct 23. doi: 10.1371/journal.pgen.1010997

PMCID:: PMC10621921

Abstract Article PDF–2.9M

Select item 99669963.

ABCG5 and ABCG8 Are Involved in Vitamin K Transport

Michinori Matsuo, Yutaka Ogata, Yoshihide Yamanashi, Tappei Takada

Nutrients. 2023 Feb; 15(4): 998. Published online 2023 Feb 16. doi: 10.3390/nu15040998

PMCID:: PMC9966996

Abstract Article PDF–1.4M

Select item 60374204.

Evidence that the ABCG5/G8-independent pathway plays a determinant role in cholesterol gallstone formation in mice

Helen H. Wang, Xiaodan Li, Shailendra B. Patel, David Q.-H. Wang

Hepatology. Author manuscript; available in PMC 2018 Jul 9.

Published in final edited form as: Hepatology. 2016 Sep; 64(3): 853–864. Published online 2016 Jun 3. doi: 10.1002/hep.28570

PMCID:: PMC6037420

Abstract Article PDF–1.8M

Select item 59958425.

Milk cholesterol concentration in mice is not affected by high cholesterol diet- or genetically-induced hypercholesterolaemia

Lidiya G. Dimova, Mirjam A. M. Lohuis, Vincent W. Bloks, Uwe J. F. Tietge, Henkjan J. Verkade

Sci Rep. 2018; 8: 8824. Published online 2018 Jun 11. doi: 10.1038/s41598-018-27115-8

PMCID:: PMC5995842

Abstract Article PDF–1.1M

Select item 46096266.

GRP78 rescues the ABCG5 ABCG8 sterol transporter in db/db mice

Yuhuan Wang, Kai Su, Nadezhda S. Sabeva, Ailing Ji, Deneys R. van der Westhuyzen, Fabienne Foufelle, Xia Gao, Gregory A. Graf

Metabolism. Author manuscript; available in PMC 2016 Nov 1.

Published in final edited form as: Metabolism. 2015 Nov; 64(11): 1435–1443. Published online 2015 Aug 15. doi: 10.1016/j.metabol.2015.08.005

PMCID:: PMC4609626

Abstract Article PDF–774K

Select item 45275857.

Sterol Transfer by ABCG5 and ABCG8: IN VITRO ASSAY AND RECONSTITUTION

Jin Wang, Fang Sun, Da-wei Zhang, Yongming Ma, Fang Xu, Jitendra D. Belani, Jonathan C. Cohen, Helen H. Hobbs, Xiao-Song Xie

J Biol Chem. Author manuscript; available in PMC 2015 Aug 6.

Published in final edited form as: J Biol Chem. 2006 Sep 22; 281(38): 27894–27904. Published online 2006 Jul 25. doi: 10.1074/jbc.M605603200

PMCID:: PMC4527585

Abstract Article PDF–4.7M

Select item 44908658.

ABCG5/G8 Deficiency in Mice Reduces Dietary Triacylglycerol and Cholesterol Transport into the Lymph

Linda S. Zhang, Min Xu, Qing Yang, Danwen Lou, Philip N. Howles, Patrick Tso

Lipids. Author manuscript; available in PMC 2015 Jul 3.

Published in final edited form as: Lipids. 2015 Apr; 50(4): 371–379. Published online 2015 Feb 13. doi: 10.1007/s11745-015-3995-y

PMCID:: PMC4490865

Abstract Article PDF–1.4M

Select item 43066869.

Relative roles of ABCG5/ABCG8 in liver and intestine

Jin Wang, Matthew A. Mitsche, Dieter Lütjohann, Jonathan C. Cohen, Xiao-Song Xie, Helen H. Hobbs

J Lipid Res. 2015 Feb; 56(2): 319–330. doi: 10.1194/jlr.M054544

PMCID:: PMC4306686

Abstract Article PDF–1.4M

Select item 414946710.

GATA4 and GATA6 regulate intestinal epithelial cytodifferentiation during development

Emily M. Walker, Cayla A. Thompson, Michele A. Battle

Dev Biol. Author manuscript; available in PMC 2015 Aug 15.

Published in final edited form as: Dev Biol. 2014 Aug 15; 392(2): 283–294. Published online 2014 Jun 12. doi: 10.1016/j.ydbio.2014.05.017

PMCID:: PMC4149467

Abstract Article PDF–2.0M

Select item 396495511.

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data

Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson

Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977

PMCID:: PMC3964955

Abstract Article PDF–5.7M

Select item 379546412.

Platelet hyperreactivity explains the bleeding abnormality and macrothrombocytopenia in a murine model of sitosterolemia

Taisuke Kanaji, Sachiko Kanaji, Robert R. Montgomery, Shailendra B. Patel, Peter J. Newman

Blood. 2013 Oct 10; 122(15): 2732–2742. Prepublished online 2013 Aug 7. doi: 10.1182/blood-2013-06-510461

PMCID:: PMC3795464

Abstract Article

Select item 362039413.

Phytosterol Feeding Causes Toxicity in ABCG5/G8 Knockout Mice

Allison L. McDaniel, Heather M. Alger, Janet K. Sawyer, Kathryn L. Kelley, Nancy D. Kock, J. Mark Brown, Ryan E. Temel, Lawrence L. Rudel

Am J Pathol. 2013 Apr; 182(4): 1131–1138. doi: 10.1016/j.ajpath.2012.12.014

PMCID:: PMC3620394

Abstract Article PDF–930K

Select item 358886914.

Dietary xenosterols lead to infertility and loss of abdominal adipose tissue in sterolin-deficient mice

Curzio Solca, G. Stephen Tint, Shailendra B. Patel

J Lipid Res. 2013 Feb; 54(2): 397–409. doi: 10.1194/jlr.M031476

PMCID:: PMC3588869

Abstract Article PDF–1.7M

Select item 357241015.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163