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Items: 1 to 20 of 39

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Interaction of Filamin C with Actin Is Essential for Cardiac Development and Function
Xiaohai Zhou, Xi Fang, Sujay S. Ithychanda, Tongbin Wu, Yusu Gu, Chao Chen, Li Wang, Julius Bogomolovas, Jun Qin, Ju Chen
Circ Res. Author manuscript; available in PMC 2024 Aug 18.
Published in final edited form as: Circ Res. 2023 Aug 18; 133(5): 400–411. Published online 2023 Jul 26. doi: 10.1161/CIRCRESAHA.123.322750
PMCID:
PMC10529502
AbstractArticlePDF–1.2M
3.
KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility
Juan Gu, Pingyang Ke, Haokun Guo, Jing Liu, Yan Liu, Xin Tian, Zhuo Huang, Xin Xu, Demei Xu, Yuanlin Ma, Xuefeng Wang, Fei Xiao
Cell Death Differ. 2023 Jul; 30(7): 1726–1741. Published online 2023 May 4. doi: 10.1038/s41418-023-01174-5
PMCID:
PMC10307852
AbstractArticlePDF–8.8M
4.
Three-dimensional microCT imaging of mouse heart development from early post-implantation to late fetal stages
Nanbing Li-Villarreal, Tara L. Rasmussen, Audrey E. Christiansen, Mary E. Dickinson, Chih-Wei Hsu
Mamm Genome. 2023; 34(2): 156–165. Published online 2023 Jan 3. doi: 10.1007/s00335-022-09976-7
PMCID:
PMC10290591
AbstractArticlePDF–3.2M
5.
Filamin C is Essential for mammalian myocardial integrity
Tongbin Wu, Yujun Xu, Lunfeng Zhang, Zhengyu Liang, Xiaohai Zhou, Sylvia M. Evans, Ju Chen
PLoS Genet. 2023 Jan; 19(1): e1010630. Published online 2023 Jan 27. doi: 10.1371/journal.pgen.1010630
PMCID:
PMC9907827
AbstractArticlePDF–3.3M
6.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
7.
Subcellular Remodeling in Filamin C Deficient Mouse Hearts Impairs Myocyte Tension Development during Progression of Dilated Cardiomyopathy
Joseph D. Powers, Natalie J. Kirkland, Canzhao Liu, Swithin S. Razu, Xi Fang, Adam J. Engler, Ju Chen, Andrew D. McCulloch
Int J Mol Sci. 2022 Jan; 23(2): 871. Published online 2022 Jan 14. doi: 10.3390/ijms23020871
PMCID:
PMC8779483
AbstractArticlePDF–19M
8.
Myopathy associated LDB3 mutation causes Z-disc disassembly and protein aggregation through PKCα and TSC2-mTOR downregulation
Pankaj Pathak, Yotam Blech-Hermoni, Kalpana Subedi, Jessica Mpamugo, Charissa Obeng-Nyarko, Rachel Ohman, Ilda Molloy, Malcolm Kates, Jessica Hale, Stacey Stauffer, Shyam K. Sharan, Ami Mankodi
Commun Biol. 2021; 4: 355. Published online 2021 Mar 19. doi: 10.1038/s42003-021-01864-1
PMCID:
PMC7979776
AbstractArticlePDF–5.3M
9.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
10.
FLNC Expression Level Influences the Activity of TEAD-YAP/TAZ Signaling
Anastasia Knyazeva, Aleksandr Khudiakov, Raquel Vaz, Aleksey Muravyev, Ksenia Sukhareva, Thomas Sejersen, Anna Kostareva
Genes (Basel) 2020 Nov; 11(11): 1343. Published online 2020 Nov 13. doi: 10.3390/genes11111343
PMCID:
PMC7696573
AbstractArticlePDF–1.7M
11.
Homozygous expression of the myofibrillar myopathy-associated p.W2710X filamin C variant reveals major pathomechanisms of sarcomeric lesion formation
Julia Schuld, Zacharias Orfanos, Frédéric Chevessier, Britta Eggers, Lorena Heil, Julian Uszkoreit, Andreas Unger, Gregor Kirfel, Peter F. M. van der Ven, Katrin Marcus, Wolfgang A. Linke, Christoph S. Clemen, Rolf Schröder, Dieter O. Fürst
Acta Neuropathol Commun. 2020; 8: 154. Published online 2020 Sep 4. doi: 10.1186/s40478-020-01001-9
PMCID:
PMC7650280
AbstractArticlePDF–16M
12.
Loss of Filamin C is catastrophic for heart function
Yangzhao Zhou, Ze’e Chen, Lunfeng Zhang, Mason Zhu, Changming Tan, Xinmin Zhou, Sylvia M Evans, Xi Fang, Wei Feng, Ju Chen
Circulation. Author manuscript; available in PMC 2021 Mar 10.
Published in final edited form as: Circulation. 2020 Mar 10; 141(10): 869–871. Published online 2020 Mar 9. doi: 10.1161/CIRCULATIONAHA.119.044061
PMCID:
PMC7583669
ArticlePDF–790K
13.
Methyltransferase-like 21e inhibits 26S proteasome activity to facilitate hypertrophy of type IIb myofibers
Chao Wang, Bin Zhang, Anna C. Ratliff, Justine Arrington, Jingjuan Chen, Yan Xiong, Feng Yue, Yaohui Nie, Keping Hu, Wen Jin, W. Andy Tao, Christine A. Hrycyna, Xiaobo Sun, Shihuan Kuang
FASEB J. 2019 Aug; 33(8): 9672–9684. Published online 2019 Jun 4. doi: 10.1096/fj.201900582R
PMCID:
PMC6993925
AbstractArticle
14.
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors
Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman
Cell. Author manuscript; available in PMC 2019 Dec 13.
Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025
Correction in:
Cell. 2019 Jul 11; 178(2): 507–508.
PMCID:
PMC6298040
AbstractArticlePDF–1.2M
15.
LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow
Hui-yuan Tseng, Anna V. Samarelli, Patricia Kammerer, Sarah Scholze, Tilman Ziegler, Roland Immler, Roy Zent, Markus Sperandio, Charles R. Sanders, Reinhard Fässler, Ralph T. Böttcher
J Cell Sci. 2018 Nov 15; 131(22): jcs218214. Published online 2018 Nov 21. doi: 10.1242/jcs.218214
PMCID:
PMC6262777
AbstractArticle
16.
HSPB7 is indispensable for heart development by modulating actin filament assembly
Tongbin Wu, Yongxin Mu, Julius Bogomolovas, Xi Fang, Jennifer Veevers, Roberta B. Nowak, Christopher T. Pappas, Carol C. Gregorio, Sylvia M. Evans, Velia M. Fowler, Ju Chen
Proc Natl Acad Sci U S A. 2017 Nov 7; 114(45): 11956–11961. Published online 2017 Oct 23. doi: 10.1073/pnas.1713763114
PMCID:
PMC5692592
AbstractArticlePDF–1.1M
17.
HSPB7 prevents cardiac conduction system defect through maintaining intercalated disc integrity
Wern-Chir Liao, Liang-Yi Juo, Yen-Ling Shih, Yen-Hui Chen, Yu-Ting Yan
PLoS Genet. 2017 Aug; 13(8): e1006984. Published online 2017 Aug 21. doi: 10.1371/journal.pgen.1006984
PMCID:
PMC5587339
AbstractArticlePDF–59M
18.
Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function
Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang
Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626
PMCID:
PMC5381226
AbstractArticlePDF–1.4M
19.
HSPB7 interacts with dimerized FLNC and its absence results in progressive myopathy in skeletal muscles
Liang-Yi Juo, Wern-Chir Liao, Yen-Ling Shih, Bih-Ying Yang, An-Bang Liu, Yu-Ting Yan
J Cell Sci. 2016 Apr 15; 129(8): 1661–1670. doi: 10.1242/jcs.179887
PMCID:
PMC4852768
AbstractArticle
20.
Elf5-centered transcription factor hub controls trophoblast stem cell self-renewal and differentiation through stoichiometry-sensitive shifts in target gene networks
Paulina A. Latos, Arnold R. Sienerth, Alexander Murray, Claire E. Senner, Masanaga Muto, Masahito Ikawa, David Oxley, Sarah Burge, Brian J. Cox, Myriam Hemberger
Genes Dev. 2015 Dec 1; 29(23): 2435–2448. doi: 10.1101/gad.268821.115
PMCID:
PMC4691948
AbstractArticlePDF–1.0M

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