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Items: 1 to 20 of 26

1.
Epigenomic and transcriptomic analyses define core cell types, genes and targetable mechanisms for kidney disease
Hongbo Liu, Tomohito Doke, Dong Guo, Xin Sheng, Ziyuan Ma, Joseph Park, Ha My T. Vy, Girish N. Nadkarni, Amin Abedini, Zhen Miao, Matthew Palmer, Benjamin F. Voight, Hongzhe Li, Christopher D. Brown, Marylyn D. Ritchie, Yan Shu, Katalin Susztak
Nat Genet. Author manuscript; available in PMC 2024 Dec 9.
Published in final edited form as: Nat Genet. 2022 Jul; 54(7): 950–962. Published online 2022 Jun 16. doi: 10.1038/s41588-022-01097-w
PMCID:
PMC11626562
AbstractArticlePDF–10M
2.
Identification of direct connections between the dura and the brain
Leon CD Smyth, Di Xu, Serhat V Okar, Taitea Dykstra, Justin Rustenhoven, Zachary Papadopoulos, Kesshni Bhasiin, Min Woo Kim, Antoine Drieu, Tornike Mamuladze, Susan Blackburn, Xingxing Gu, María I Gaitán, Govind Nair, Steffen E Storck, Siling Du, Michael A White, Peter Bayguinov, Igor Smirnov, Krikor Dikranian, Daniel S Reich, Jonathan Kipnis
Nature. Author manuscript; available in PMC 2024 Sep 1.
Published in final edited form as: Nature. 2024 Mar; 627(8002): 165–173. Published online 2024 Feb 7. doi: 10.1038/s41586-023-06993-7
PMCID:
PMC11254388
AbstractArticlePDF–6.7M
3.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
4.
The lipid flippase SLC47A1 blocks metabolic vulnerability to ferroptosis
Zhi Lin, Jiao Liu, Fei Long, Rui Kang, Guido Kroemer, Daolin Tang, Minghua Yang
Nat Commun. 2022; 13: 7965. Published online 2022 Dec 27. doi: 10.1038/s41467-022-35707-2
PMCID:
PMC9794750
AbstractArticlePDF–8.9M
5.
MATE1 Deficiency Exacerbates Dofetilide-Induced Proarrhythmia
Muhammad Erfan Uddin, Eric D. Eisenmann, Yang Li, Kevin M. Huang, Dominique A. Garrison, Zahra Talebi, Alice A. Gibson, Yan Jin, Mahesh Nepal, Ingrid M. Bonilla, Qiang Fu, Xinxin Sun, Alec Millar, Mikhail Tarasov, Christopher E. Jay, Xiaoming Cui, Heidi J. Einolf, Ryan M. Pelis, Sakima A. Smith, Przemysław B. Radwański, Douglas H. Sweet, Jörg König, Martin F. Fromm, Cynthia A. Carnes, Shuiying Hu, Alex Sparreboom
Int J Mol Sci. 2022 Aug; 23(15): 8607. Published online 2022 Aug 3. doi: 10.3390/ijms23158607
PMCID:
PMC9369325
AbstractArticlePDF–2.5M
6.
Trospium Chloride Transport by Mouse Drug Carriers of the Slc22 and Slc47 Families
Matthias Gorecki, Simon F. Müller, Regina Leidolf, Joachim Geyer
Int J Mol Sci. 2021 Jan; 22(1): 22. Published online 2020 Dec 22. doi: 10.3390/ijms22010022
PMCID:
PMC7792585
AbstractArticlePDF–845K
7.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
8.
Mechanism of Altered Metformin Distribution in Nonalcoholic Steatohepatitis
John D. Clarke, Anika L. Dzierlenga, Nicholas R. Nelson, Hui Li, Samantha Werts, Michael J. Goedken, Nathan J. Cherrington
Diabetes. 2015 Sep; 64(9): 3305–3313. Published online 2015 May 27. doi: 10.2337/db14-1947
PMCID:
PMC4542448
AbstractArticlePDF–1.1M
9.
Lack of metformin effect on mouse embryo AMPK activity: implications for metformin treatment during pregnancy
Hyung-yul Lee, Dan Wei, Mary R. Loeken
Diabetes Metab Res Rev. Author manuscript; available in PMC 2014 Apr 20.
Published in final edited form as: Diabetes Metab Res Rev. 2014 Jan; 30(1): 23–30. doi: 10.1002/dmrr.2451
PMCID:
PMC3992340
AbstractArticlePDF–603K
10.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
11.
Ondansetron Can Enhance Cisplatin-Induced Nephrotoxicity via Inhibition of Multiple Toxin and Extrusion Proteins (MATEs)
Qing Li, Dong Guo, Zhongqi Dong, Wei Zhang, Lei K. Zhang, Shiew-Mei Huang, James E. Polli, Yan Shu
Toxicol Appl Pharmacol. Author manuscript; available in PMC 2014 Nov 15.
Published in final edited form as: Toxicol Appl Pharmacol. 2013 Nov 15; 273(1): 10.1016/j.taap.2013.08.024. Published online 2013 Aug 31. doi: 10.1016/j.taap.2013.08.024
PMCID:
PMC3830718
AbstractArticlePDF–2.0M
12.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
13.
Twelve Transmembrane Helices Form the Functional Core of Mammalian MATE1 (Multidrug and Toxin Extruder 1) Protein
Xiaohong Zhang, Xiao He, Joseph Baker, Florence Tama, Geoffrey Chang, Stephen H. Wright
J Biol Chem. 2012 Aug 10; 287(33): 27971–27982. Published online 2012 Jun 21. doi: 10.1074/jbc.M112.386979
PMCID:
PMC3431635
AbstractArticlePDF–4.6M
14.
Loss of multidrug and toxin extrusion 1 (MATE1) is associated with metformin-induced lactic acidosis
K Toyama, A Yonezawa, S Masuda, R Osawa, M Hosokawa, S Fujimoto, N Inagaki, K Inui, T Katsura
Br J Pharmacol. 2012 Jun; 166(3): 1183–1191. doi: 10.1111/j.1476-5381.2012.01853.x
PMCID:
PMC3417438
AbstractArticlePDF–694K
15.
Deficiency of Multidrug and Toxin Extrusion 1 Enhances Renal Accumulation of Paraquat and Deteriorates Kidney Injury in Mice
Qing Li, Xiujuan Peng, Hyekyung Yang, Hongbing Wang, Yan Shu
Mol Pharm. 2011 Dec 5; 8(6): 2476–2483. Published online 2011 Sep 29. doi: 10.1021/mp200395f
PMCID:
PMC3230245
AbstractArticlePDF–2.9M
16.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
17.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
18.
The European Renal Genome Project: An Integrated Approach Towards Understanding the Genetics of Kidney Development and Disease
TE Willnow, C Antignac, AW Brändli, EI Christensen, RD Cox, D Davidson, JA Davies, O Devuyst, G Eichele, ND Hastie, PJ Verroust, A Schedl, IC Meij
Organogenesis. 2005 Apr-Jun; 2(2): 42–47. doi: 10.4161/org.2.2.2118
PMCID:
PMC2634085
AbstractArticlePDF–629K
19.
Tissue distribution, ontogeny and induction of the transporters Multidrug and toxin extrusion (MATE) 1 and MATE2 mRNA expression levels in mice
Andrew J. Lickteig, Xingguo Cheng, Lisa M. Augustine, Curtis D. Klaassen, Nathan J. Cherrington
Life Sci. Author manuscript; available in PMC 2009 Jul 4.
Published in final edited form as: Life Sci. 2008 Jul 4; 83(1-2): 59–64. Published online 2008 May 18. doi: 10.1016/j.lfs.2008.05.004
PMCID:
PMC2494953
AbstractArticlePDF–712K
20.
BGEM: An In Situ Hybridization Database of Gene Expression in the Embryonic and Adult Mouse Nervous System
Susan Magdaleno, Patricia Jensen, Craig L Brumwell, Anna Seal, Karen Lehman, Andrew Asbury, Tony Cheung, Tommie Cornelius, Diana M Batten, Christopher Eden, Shannon M Norland, Dennis S Rice, Nilesh Dosooye, Sundeep Shakya, Perdeep Mehta, Tom Curran
PLoS Biol. 2006 Apr; 4(4): e86. Published online 2006 Mar 28. doi: 10.1371/journal.pbio.0040086
PMCID:
PMC1413568
ArticlePDF–99K

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