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Select item 111134131.

Tubulin acetylation: responsible enzymes, biological functions and human diseases

Lin Li, Xiang-Jiao Yang

Cell Mol Life Sci. 2015 Nov; 72(22): 4237–4255. Published online 2015 Jul 31. doi: 10.1007/s00018-015-2000-5

PMCID:: PMC11113413

Abstract Article PDF–1.9M

Select item 110248602.

HDAC6-dependent deacetylation of NGF dictates its ubiquitination and maintains primordial follicle dormancy

Tuo Zhang, Yuntong Tong, Rengguang Zhu, Yaoyun Liang, Jixian Zhang, Chujiao Hu, Meina He, Zhu Hu, Zhiyi Shen, Jin Niu, Jingjing Zhang, Yuanyuan Yu, Bangming Jin, Shan Lei, Zhirui Zeng, Yingmin Wu, Zengmei Cheng, Ziwen Xiao, Bing Guo, Shuyun Zhao, Guoqiang Xu, Wei Pan, Tengxiang Chen

Theranostics. 2024; 14(6): 2345–2366. Published online 2024 Mar 25. doi: 10.7150/thno.95164

PMCID:: PMC11024860

Abstract Article PDF–13M

Select item 109159913.

Selective HDAC6 inhibition protects against blood–brain barrier dysfunction after intracerebral hemorrhage

Cuiying Peng, Yilin Wang, Zhiping Hu, Chunli Chen

CNS Neurosci Ther. 2024 Mar; 30(3): e14429. Published online 2023 Sep 4. doi: 10.1111/cns.14429

PMCID:: PMC10915991

Abstract Article PDF–50M

Select item 108538984.

HTRA1 promotes EMT through the HDAC6/Ac‐α‐tubulin pathway in human GBM cells

Wenbo Zhao, Yibo Wu, Shuai Wang, Feihu Zhao, Wenyu Liu, Zhiyi Xue, Lin Zhang, Jian Wang, Mingzhi Han, Xingang Li, Bin Huang

CNS Neurosci Ther. 2024 Feb; 30(2): e14605. Published online 2024 Feb 9. doi: 10.1111/cns.14605

PMCID:: PMC10853898

Abstract Article PDF–66M

Select item 108509545.

HDAC6/aggresome processing pathway importance for inflammasome formation is context-dependent

Longlong Wang, Shihua Shi, Adeline Unterreiner, Ronan Kapetanovic, Sucheta Ghosh, Jacint Sanchez, Selma Aslani, Yuan Xiong, Chi-Lin Hsu, Katherine A. Donovan, Christopher J. Farady, Eric S. Fischer, Frédéric Bornancin, Patrick Matthias

J Biol Chem. 2024 Feb; 300(2): 105638. Published online 2024 Jan 8. doi: 10.1016/j.jbc.2024.105638

PMCID:: PMC10850954

Abstract Article PDF–1.9M

Select item 106277866.

ESYT1 tethers the ER to mitochondria and is required for mitochondrial lipid and calcium homeostasis

Alexandre Janer, Jordan L Morris, Michiel Krols, Hana Antonicka, Mari J Aaltonen, Zhen-Yuan Lin, Hanish Anand, Anne-Claude Gingras, Julien Prudent, Eric A Shoubridge

Life Sci Alliance. 2024 Jan; 7(1): e202302335. Published online 2023 Nov 6. doi: 10.26508/lsa.202302335

PMCID:: PMC10627786

Abstract Article PDF–5.2M

Select item 105166277.

The HDAC6-RNF168 axis regulates H2A/H2A.X ubiquitination to enable double-strand break repair

Lingyu Qiu, Wenchao Xu, Xiaopeng Lu, Feng Chen, Yongcan Chen, Yuan Tian, Qian Zhu, Xiangyu Liu, Yongqing Wang, Xin-Hai Pei, Xingzhi Xu, Jun Zhang, Wei-Guo Zhu

Nucleic Acids Res. 2023 Sep 22; 51(17): 9166–9182. Published online 2023 Jul 28. doi: 10.1093/nar/gkad631

PMCID:: PMC10516627

Abstract Article PDF–2.5M

Select item 104509468.

Histone deacetylase 6’s function in viral infection, innate immunity, and disease: latest advances

Min Qu, Huijun Zhang, Pengyuan Cheng, Ashenafi Kiros Wubshet, Xiangping Yin, Xiangwei Wang, Yuefeng Sun

Front Immunol. 2023; 14: 1216548. Published online 2023 Aug 11. doi: 10.3389/fimmu.2023.1216548

PMCID:: PMC10450946

Abstract Article PDF–1.4M

Select item 102374229.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 995018310.

CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment

Daphne J. Smits, Jordy Dekker, Rachel Schot, Brahim Tabarki, Amal Alhashem, Jeroen A. A. Demmers, Dick H. W. Dekkers, Antonio Romito, Peter J. van der Spek, Tjakko J. van Ham, Aida M. Bertoli-Avella, Grazia M. S. Mancini

Hum Genet. 2023; 142(3): 379–397. Published online 2022 Dec 20. doi: 10.1007/s00439-022-02511-3

PMCID:: PMC9950183

Abstract Article PDF–2.4M

Select item 984353211.

HDAC6 regulates human erythroid differentiation through modulation of JAK2 signalling

Pascal Vong, Kahia Messaoudi, Nicolas Jankovsky, Cathy Gomilla, Yohann Demont, Alexis Caulier, Guillaume Jedraszak, Julien Demagny, Stefan Djordjevic, Thomas Boyer, Jean Pierre Marolleau, Jacques Rochette, Hakim Ouled‐Haddou, Loïc Garçon

J Cell Mol Med. 2023 Jan; 27(2): 174–188. Published online 2022 Dec 28. doi: 10.1111/jcmm.17559

PMCID:: PMC9843532

Abstract Article PDF–2.1M

Select item 983805112.

Inhibition of histone deacetylase 6 destabilizes ERK phosphorylation and suppresses cancer proliferation via modulation of the tubulin acetylation-GRP78 interaction

Onsurang Wattanathamsan, Naphat Chantaravisoot, Piriya Wongkongkathep, Sakkarin Kungsukool, Paninee Chetprayoon, Pithi Chanvorachote, Chanida Vinayanuwattikun, Varisa Pongrakhananon

J Biomed Sci. 2023; 30: 4. Published online 2023 Jan 13. doi: 10.1186/s12929-023-00898-3

PMCID:: PMC9838051

Abstract Article PDF–2.6M

Select item 981161913.

The lysosomal Ragulator complex activates NLRP3 inflammasome in vivo via HDAC6

Kohei Tsujimoto, Tatsunori Jo, Daiki Nagira, Hachiro Konaka, Jeong Hoon Park, Shin‐ichiro Yoshimura, Akinori Ninomiya, Fuminori Sugihara, Takehiro Hirayama, Eri Itotagawa, Yusei Matsuzaki, Yuki Takaichi, Wataru Aoki, Shotaro Saita, Shuhei Nakamura, Andrea Ballabio, Shigeyuki Nada, Masato Okada, Hyota Takamatsu, Atsushi Kumanogoh

EMBO J. 2023 Jan; 42(1): e111389. Published online 2022 Nov 29. doi: 10.15252/embj.2022111389

PMCID:: PMC9811619

Abstract Article PDF–4.2M

Select item 977659114.

HDAC6 Inhibition Alleviates Ischemia- and Cisplatin-Induced Acute Kidney Injury by Promoting Autophagy

Lang Shi, Zhixia Song, Chenglong Li, Fangjing Deng, Yao Xia, Jing Huang, Xiongfei Wu, Jiefu Zhu

Cells. 2022 Dec; 11(24): 3951. Published online 2022 Dec 7. doi: 10.3390/cells11243951

PMCID:: PMC9776591

Abstract Article PDF–13M

Select item 958728615.

HDAC6-dependent deacetylation of TAK1 enhances sIL-6R release to promote macrophage M2 polarization in colon cancer

Guangying Xu, Liling Niu, Youhui Wang, Guang Yang, Xingwu Zhu, Yuan Yao, Gang Zhao, Shaowei Wang, Hui Li

Cell Death Dis. 2022 Oct; 13(10): 888. Published online 2022 Oct 21. doi: 10.1038/s41419-022-05335-1

PMCID:: PMC9587286

Abstract Article PDF–6.5M

Select item 948160216.

Electrostatic and steric effects underlie acetylation-induced changes in ubiquitin structure and function

Simon Maria Kienle, Tobias Schneider, Katrin Stuber, Christoph Globisch, Jasmin Jansen, Florian Stengel, Christine Peter, Andreas Marx, Michael Kovermann, Martin Scheffner

Nat Commun. 2022; 13: 5435. Published online 2022 Sep 16. doi: 10.1038/s41467-022-33087-1

PMCID:: PMC9481602

Abstract Article PDF–3.7M

Select item 941076317.

iPSC-derived neurons profiling reveals GABAergic circuit disruption and acetylated α-tubulin defect which improves after iHDAC6 treatment in Rett syndrome

Elisa Landucci, Margherita Brindisi, Laura Bianciardi, Lorenza M. Catania, Sergio Daga, Susanna Croci, Elisa Frullanti, Chiara Fallerini, Stefania Butini, Simone Brogi, Simone Furini, Riccardo Melani, Angelo Molinaro, Flaminia Clelia Lorenzetti, Valentina Imperatore, Sonia Amabile, Jessica Mariani, Francesca Mari, Francesca Ariani, Tommaso Pizzorusso, Anna Maria Pinto, Flora M. Vaccarino, Giuseppe Campiani, Alessandra Renieri, Ilaria Meloni

Exp Cell Res. Author manuscript; available in PMC 2022 Aug 25.

Published in final edited form as: Exp Cell Res. 2018 Jul 15; 368(2): 225–235. Published online 2018 May 4. doi: 10.1016/j.yexcr.2018.05.001

PMCID:: PMC9410763

Abstract Article PDF–1.0M

Select item 934857618.

Chr21 protein–protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer’s disease

Julia Viard, Yann Loe-Mie, Rachel Daudin, Malik Khelfaoui, Christine Plancon, Anne Boland, Francisco Tejedor, Richard L Huganir, Eunjoon Kim, Makoto Kinoshita, Guofa Liu, Volker Haucke, Thomas Moncion, Eugene Yu, Valérie Hindie, Henri Bléhaut, Clotilde Mircher, Yann Herault, Jean-François Deleuze, Jean-Christophe Rain, Michel Simonneau, Aude-Marie Lepagnol-Bestel

Life Sci Alliance. 2022 Dec; 5(12): e202101205. Published online 2022 Aug 1. doi: 10.26508/lsa.202101205

PMCID:: PMC9348576

Abstract Article PDF–3.0M

Select item 927928519.

Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery

Pierre C. Havugimana, Raghuveera Kumar Goel, Sadhna Phanse, Ahmed Youssef, Dzmitry Padhorny, Sergei Kotelnikov, Dima Kozakov, Andrew Emili

Nat Commun. 2022; 13: 4043. Published online 2022 Jul 13. doi: 10.1038/s41467-022-31809-z

PMCID:: PMC9279285

Abstract Article PDF–2.5M

Select item 925732120.

MIIP inhibits clear cell renal cell carcinoma proliferation and angiogenesis via negative modulation of the HIF-2α-CYR61 axis

Fengqi Yan, Qinhao Wang, Mingyuan Xia, Yi Ru, Wei Hu, Guang Yan, Xin Xiong, Mei Zhang, Jiancai Wang, Qi Li, Bo Zhang, He Wang, Wei Lin, Guojun Wu, Xia Li

Cancer Biol Med. 2022 Jun 15; 19(6): 818–835. Published online 2021 Dec 22. doi: 10.20892/j.issn.2095-3941.2020.0296

PMCID:: PMC9257321

Abstract Article PDF–2.3M

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