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Select item 109457071.

Comparative interactome analysis of α-arrestin families in human and Drosophila

Kyung-Tae Lee, Inez KA Pranoto, Soon-Young Kim, Hee-Joo Choi, Ngoc Bao To, Hansong Chae, Jeong-Yeon Lee, Jung-Eun Kim, Young V Kwon, Jin-Wu Nam

eLife. 2024; 12: RP88328. Published online 2024 Jan 25. doi: 10.7554/eLife.88328

PMCID:: PMC10945707

Abstract Article PDF–2.8M

Select item 104945252.

Nuclear lamin facilitates collective border cell invasion into confined spaces in vivo

Lauren Penfield, Denise J. Montell

J Cell Biol. 2023 Nov 6; 222(11): e202212101. Published online 2023 Sep 11. doi: 10.1083/jcb.202212101

PMCID:: PMC10494525

Abstract Article PDF–8.8M

Select item 99787933.

Sphingolipids in neurodegenerative diseases

Xueyang Pan, Debdeep Dutta, Shenzhao Lu, Hugo J. Bellen

Front Neurosci. 2023; 17: 1137893. Published online 2023 Feb 16. doi: 10.3389/fnins.2023.1137893

PMCID:: PMC9978793

Abstract Article PDF–6.2M

Select item 98890874.

Exploring therapeutic strategies for infantile neuronal axonal dystrophy (INAD/PARK14)

Guang Lin, Burak Tepe, Geoff McGrane, Regine C Tipon, Gist Croft, Leena Panwala, Amanda Hope, Agnes JH Liang, Zhongyuan Zuo, Seul Kee Byeon, Lily Wang, Akhilesh Pandey, Hugo J Bellen

eLife. 2023; 12: e82555. Published online 2023 Jan 16. doi: 10.7554/eLife.82555

PMCID:: PMC9889087

Abstract Article PDF–16M

Select item 93783615.

‘Fly’ing from rare to common neurodegenerative disease mechanisms

Mengqi Ma, Matthew J. Moulton, Shenzhao Lu, Hugo J. Bellen

Trends Genet. Author manuscript; available in PMC 2023 Sep 1.

Published in final edited form as: Trends Genet. 2022 Sep; 38(9): 972–984. Published online 2022 Apr 25. doi: 10.1016/j.tig.2022.03.018

PMCID:: PMC9378361

Abstract Article PDF–1.0M

Select item 92396806.

An expanded toolkit for Drosophila gene tagging using synthesized homology donor constructs for CRISPR-mediated homologous recombination

Oguz Kanca, Jonathan Zirin, Yanhui Hu, Burak Tepe, Debdeep Dutta, Wen-Wen Lin, Liwen Ma, Ming Ge, Zhongyuan Zuo, Lu-Ping Liu, Robert W Levis, Norbert Perrimon, Hugo J Bellen

eLife. 2022; 11: e76077. Published online 2022 Jun 20. doi: 10.7554/eLife.76077

PMCID:: PMC9239680

Abstract Article PDF–1.2M

Select item 86644867.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 84328418.

iPLA₂-VIA is required for healthy aging of neurons, muscle, and the female germline in Drosophila melanogaster

Surya Jyoti Banerjee, Adina Schonbrun, Sogol Eizadshenass, Shimshon Benji, Yaakov Tzvi Cantor, Liam Eliach, Matthew Lubin, Zev Narrowe, Jeremy Purow, Benjamin Shulman, Leib Wiener, Josefa Steinhauer

PLoS One. 2021; 16(9): e0256738. Published online 2021 Sep 10. doi: 10.1371/journal.pone.0256738

PMCID:: PMC8432841

Abstract Article PDF–4.9M

Select item 82704849.

Loss of UCHL1 rescues the defects related to Parkinson’s disease by suppressing glycolysis

Su Jin Ham, Daewon Lee, Wen Jun Xu, Eunjoo Cho, Sekyu Choi, Soohong Min, Sunghyouk Park, Jongkyeong Chung

Sci Adv. 2021 Jul; 7(28): eabg4574. Published online 2021 Jul 9. doi: 10.1126/sciadv.abg4574

PMCID:: PMC8270484

Abstract Article PDF–7.4M

Select item 799831610.

The Importance of Drosophila melanogaster Research to UnCover Cellular Pathways Underlying Parkinson’s Disease

Melissa Vos, Christine Klein

Cells. 2021 Mar; 10(3): 579. Published online 2021 Mar 6. doi: 10.3390/cells10030579

PMCID:: PMC7998316

Abstract Article PDF–1.7M

Select item 782618811.

Unraveling the Genetic Basis for the Rapid Diversification of Male Genitalia between Drosophila Species

Joanna F D Hagen, Cláudia C Mendes, Shamma R Booth, Javier Figueras Jimenez, Kentaro M Tanaka, Franziska A Franke, Luis Baudouin-Gonzalez, Amber M Ridgway, Saad Arif, Maria D S Nunes, Alistair P McGregor

Mol Biol Evol. 2021 Feb; 38(2): 437–448. Published online 2020 Sep 15. doi: 10.1093/molbev/msaa232

Correction in:: Mol Biol Evol. 2022 Oct; 39(10): msac207.

PMCID:: PMC7826188

Abstract Article PDF–648K

Select item 761070312.

A SuperFamily-Wide Activity Atlas of Serine Hydrolases in Drosophila Melanogaster

Kundan Kumar, Amol Mhetre, Girish S. Ratnaparkhi, Siddhesh S. Kamat

Biochemistry. Author manuscript; available in PMC 2021 Oct 27.

Published in final edited form as: Biochemistry. 2021 Apr 27; 60(16): 1312–1324. Published online 2021 Apr 7. doi: 10.1021/acs.biochem.1c00171

PMCID:: PMC7610703

Abstract Article PDF–1.7M

Select item 715387613.

A course-based undergraduate research experience examining neurodegeneration in Drosophila melanogaster teaches students to think, communicate, and perform like scientists

Rebecca Delventhal, Josefa Steinhauer

PLoS One. 2020; 15(4): e0230912. Published online 2020 Apr 13. doi: 10.1371/journal.pone.0230912

PMCID:: PMC7153876

Abstract Article PDF–1.0M

Select item 696157814.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 693959215.

Lipidome-wide ¹³C flux analysis: a novel tool to estimate the turnover of lipids in organisms and cultures

Michael Schlame, Yang Xu, Hediye Erdjument-Bromage, Thomas A. Neubert, Mindong Ren

J Lipid Res. 2020 Jan; 61(1): 95–104. Published online 2019 Nov 11. doi: 10.1194/jlr.D119000318

PMCID:: PMC6939592

Abstract Article PDF–1.4M

Select item 678990716.

Parkinson’s disease-associated iPLA2-VIA/PLA2G6 regulates neuronal functions and α-synuclein stability through membrane remodeling

Akio Mori, Taku Hatano, Tsuyoshi Inoshita, Kahori Shiba-Fukushima, Takahiro Koinuma, Hongrui Meng, Shin-ichiro Kubo, Spencer Spratt, Changxu Cui, Chikara Yamashita, Yoshimi Miki, Kei Yamamoto, Tetsuya Hirabayashi, Makoto Murakami, Yoshikazu Takahashi, Hideo Shindou, Takashi Nonaka, Masato Hasegawa, Ayami Okuzumi, Yuzuru Imai, Nobutaka Hattori

Proc Natl Acad Sci U S A. 2019 Oct 8; 116(41): 20689–20699. Published online 2019 Sep 23. doi: 10.1073/pnas.1902958116