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Select item 107960891.

Recurrent Phases of Strict Protein Limitation Inhibit Tumor Growth and Restore Lifespan in A Drosophila Intestinal Cancer Model

Roxana M. Pfefferkorn, Benedikt M. Mortzfeld, Christine Fink, Jakob von Frieling, Judith Bossen, Daniela Esser, Christoph Kaleta, Philip Rosenstiel, Holger Heine, Thomas Roeder

Aging Dis. 2024 Feb 1; 15(1): 226–244. Published online 2024 Feb 1. doi: 10.14336/AD.2023.0517

PMCID:: PMC10796089

Abstract Article PDF–1.6M

Select item 103416272.

PLA2G12A as a Novel Biomarker for Colorectal Cancer with Prognostic Relevance

Eva Parisi, Ivan Hidalgo, Robert Montal, Ona Pallisé, Jordi Tarragona, Anabel Sorolla, Anna Novell, Kyra Campbell, Maria Alba Sorolla, Andreu Casali, Antonieta Salud

Int J Mol Sci. 2023 Jul; 24(13): 10889. Published online 2023 Jun 30. doi: 10.3390/ijms241310889

PMCID:: PMC10341627

Abstract Article PDF–3.4M

Select item 101129303.

Zasp52 strengthens whole embryo tissue integrity through supracellular actomyosin networks

Dina J. Ashour, Clinton H. Durney, Vicente J. Planelles-Herrero, Tim J. Stevens, James J. Feng, Katja Röper

Development. 2023 Apr 1; 150(7): dev201238. Published online 2023 Apr 3. doi: 10.1242/dev.201238

PMCID:: PMC10112930

Abstract Article

Select item 94583184.

Drosophila as a toolkit to tackle cancer and its metabolism

Hui Jiang, Taku Kimura, Han Hai, Ryodai Yamamura, Masahiro Sonoshita

Front Oncol. 2022; 12: 982751. Published online 2022 Aug 25. doi: 10.3389/fonc.2022.982751

PMCID:: PMC9458318

Abstract Article PDF–1.2M

Select item 90280145.

The MicroRNA miR-277 Controls Physiology and Pathology of the Adult Drosophila Midgut by Regulating the Expression of Fatty Acid β-Oxidation-Related Genes in Intestinal Stem Cells

Lisa Zipper, Sai Batchu, Nida Hatice Kaya, Zeus Andrea Antonello, Tobias Reiff

Metabolites. 2022 Apr; 12(4): 315. Published online 2022 Mar 31. doi: 10.3390/metabo12040315

PMCID:: PMC9028014

Abstract Article PDF–56M

Select item 88056486.

Insect Gut Regeneration

Peng Zhang, Bruce A. Edgar

Cold Spring Harb Perspect Biol. 2022 Feb; 14(2): a040915. doi: 10.1101/cshperspect.a040915

PMCID:: PMC8805648

Abstract Article PDF–1.8M

Select item 81512057.

Sensitive High-Throughput Assays for Tumour Burden Reveal the Response of a Drosophila melanogaster Model of Colorectal Cancer to Standard Chemotherapies

Jamie Adams, Andreu Casali, Kyra Campbell

Int J Mol Sci. 2021 May; 22(10): 5101. Published online 2021 May 12. doi: 10.3390/ijms22105101

PMCID:: PMC8151205

Abstract Article PDF–5.1M

Select item 78730798.

Global chromatin organizer SATB1 acts as a context-dependent regulator of the Wnt/Wg target genes

Praveena L. Ramanujam, Sonam Mehrotra, Ram Parikshan Kumar, Shreekant Verma, Girish Deshpande, Rakesh K. Mishra, Sanjeev Galande

Sci Rep. 2021; 11: 3385. Published online 2021 Feb 9. doi: 10.1038/s41598-021-81324-2

PMCID:: PMC7873079

Abstract Article PDF–3.9M

Select item 78553859.

Molecular and Biological Functions of TRIM-NHL RNA-Binding Proteins

Robert P. Connacher, Aaron C. Goldstrohm

Wiley Interdiscip Rev RNA. Author manuscript; available in PMC 2022 Mar 1.

Published in final edited form as: Wiley Interdiscip Rev RNA. 2021 Mar; 12(2): e1620. Published online 2020 Aug 1. doi: 10.1002/wrna.1620

PMCID:: PMC7855385

Abstract Article PDF–2.1M

Select item 769545210.

Opposing JAK-STAT and Wnt signaling gradients define a stem cell domain by regulating differentiation at two borders

David Melamed, Daniel Kalderon

eLife. 2020; 9: e61204. Published online 2020 Nov 2. doi: 10.7554/eLife.61204

PMCID:: PMC7695452

Abstract Article PDF–6.2M

Select item 755019211.

Topology-driven protein-protein interaction network analysis detects genetic sub-networks regulating reproductive capacity

Tarun Kumar, Leo Blondel, Cassandra G Extavour

eLife. 2020; 9: e54082. Published online 2020 Sep 9. doi: 10.7554/eLife.54082

PMCID:: PMC7550192

Abstract Article PDF–2.8M

Select item 740994912.

Disruption of EGF feedback by intestinal tumors and neighboring cells in Drosophila

Sang Ngo, Jackson Liang, Yu-Han Su, Lucy Erin O’Brien

Curr Biol. Author manuscript; available in PMC 2021 Apr 20.

Published in final edited form as: Curr Biol. 2020 Apr 20; 30(8): 1537–1546.e3. Published online 2020 Apr 2. doi: 10.1016/j.cub.2020.01.082

PMCID:: PMC7409949

Abstract Article PDF–1.2M

Select item 734672613.

Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex

Kristina N. Schaefer, Mira I. Pronobis, Clara E. Williams, Shiping Zhang, Lauren Bauer, Dennis Goldfarb, Feng Yan, M. Ben Major, Mark Peifer

Mol Biol Cell. 2020 May 1; 31(10): 992–1014. doi: 10.1091/mbc.E19-11-0647

PMCID:: PMC7346726

Abstract Article PDF–5.5M

Select item 730243114.

Identification of Endogenous Adenomatous Polyposis Coli Interaction Partners and β-Catenin-Independent Targets by Proteomics

Olesja Popow, João A. Paulo, Michael H. Tatham, Melanie S. Volk, Alejandro Rojas-Fernandez, Nicolas Loyer, Ian P. Newton, Jens Januschke, Kevin M. Haigis, Inke Näthke

Mol Cancer Res. Author manuscript; available in PMC 2020 Jun 18.

Published in final edited form as: Mol Cancer Res. 2019 Sep; 17(9): 1828–1841. Published online 2019 Jun 3. doi: 10.1158/1541-7786.MCR-18-1154

PMCID:: PMC7302431

Abstract Article PDF–2.2M

Select item 729979115.

Picking winners and losers: Cell competition in tissue development and homeostasis

Wonho Kim, Rajan Jain

Trends Genet. Author manuscript; available in PMC 2021 Jul 1.

Published in final edited form as: Trends Genet. 2020 Jul; 36(7): 490–498. Published online 2020 May 14. doi: 10.1016/j.tig.2020.04.003

PMCID:: PMC7299791

Abstract Article PDF–605K

Select item 717157116.

APC2 associates with the actin cortex through a multipart mechanism to regulate cortical actin organization and dynamics in the Drosophila ovary

Olivia Molinar-Inglis, Stacie L. Oliver, Paige Rudich, Ezgi Kunttas, Brooke M. McCartney

Cytoskeleton (Hoboken) Author manuscript; available in PMC 2020 Apr 21.

Published in final edited form as: Cytoskeleton (Hoboken). 2018 Jul; 75(7): 323–335. Published online 2018 Sep 21. doi: 10.1002/cm.21471

PMCID:: PMC7171571

Abstract Article PDF–2.1M

Select item 706739817.

Endosomal Wnt signaling proteins control microtubule nucleation in dendrites

Alexis T. Weiner, Dylan Y. Seebold, Pedro Torres-Gutierrez, Christin Folker, Rachel D. Swope, Gregory O. Kothe, Jessica G. Stoltz, Madeleine K. Zalenski, Christopher Kozlowski, Dylan J. Barbera, Mit A. Patel, Pankajam Thyagarajan, Matthew Shorey, Derek M. R. Nye, Matthew Keegan, Kana Behari, Song Song, Jeffrey D. Axelrod, Melissa M. Rolls

PLoS Biol. 2020 Mar; 18(3): e3000647. Published online 2020 Mar 12. doi: 10.1371/journal.pbio.3000647

PMCID:: PMC7067398

Abstract Article PDF–6.4M

Select item 706246618.

A large-scale resource for tissue-specific CRISPR mutagenesis in Drosophila

Fillip Port, Claudia Strein, Mona Stricker, Benedikt Rauscher, Florian Heigwer, Jun Zhou, Celine Beyersdörffer, Jana Frei, Amy Hess, Katharina Kern, Laura Lange, Nora Langner, Roberta Malamud, Bojana Pavlović, Kristin Rädecke, Lukas Schmitt, Lukas Voos, Erica Valentini, Michael Boutros

eLife. 2020; 9: e53865. Published online 2020 Feb 13. doi: 10.7554/eLife.53865