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Select item 104448901.

The deubiquitinase Leon/USP5 interacts with Atg1/ULK1 and antagonizes autophagy

Yueh-Ling Pai, Yuchieh Jay Lin, Wen-Hsin Peng, Li-Ting Huang, He-Yen Chou, Chien-Hsiang Wang, Cheng-Ting Chien, Guang-Chao Chen

Cell Death Dis. 2023 Aug; 14(8): 540. Published online 2023 Aug 22. doi: 10.1038/s41419-023-06062-x

PMCID:: PMC10444890

Abstract Article PDF–4.9M

Select item 97442312.

PR-DUB preserves Polycomb repression by preventing excessive accumulation of H2Aub1, an antagonist of chromatin compaction

Jacques Bonnet, Iulia Boichenko, Reinhard Kalb, Mathilde Le Jeune, Svetlana Maltseva, Mattia Pieropan, Katja Finkl, Beat Fierz, Jürg Müller

Genes Dev. 2022 Oct 1; 36(19-20): 1046–1061. doi: 10.1101/gad.350014.122

PMCID:: PMC9744231

Abstract Article PDF–22M

Select item 95239973.

MBD5 and MBD6 stabilize the BAP1 complex and promote BAP1-dependent cancer

Natsumi Tsuboyama, Aileen Patricia Szczepanski, Zibo Zhao, Lu Wang

Genome Biol. 2022; 23: 206. Published online 2022 Sep 30. doi: 10.1186/s13059-022-02776-x

PMCID:: PMC9523997

Abstract Article PDF–6.9M

Select item 89900004.

Usp5, Usp34, and Otu1 deubiquitylases mediate DNA repair in Drosophila melanogaster

Zoltán G. Páhi, Levente Kovács, Diána Szűcs, Barbara N. Borsos, Péter Deák, Tibor Pankotai

Sci Rep. 2022; 12: 5870. Published online 2022 Apr 7. doi: 10.1038/s41598-022-09703-x

PMCID:: PMC8990000

Abstract Article PDF–1.5M

Select item 86698345.

Tumor–host interactions through the lens of Drosophila

David Bilder, Katy Ong, Tsai-Ching Hsi, Kavya Adiga, Jung Kim

Nat Rev Cancer. Author manuscript; available in PMC 2022 May 1.

Published in final edited form as: Nat Rev Cancer. 2021 Nov; 21(11): 687–700. Published online 2021 Aug 13. doi: 10.1038/s41568-021-00387-5

PMCID:: PMC8669834

Abstract Article PDF–385K

Select item 86644866.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 81297937.

Drosophila USP22/nonstop polarizes the actin cytoskeleton during collective border cell migration

Hammed Badmos, Neville Cobbe, Amy Campbell, Richard Jackson, Daimark Bennett

J Cell Biol. 2021 Jul 5; 220(7): e202007005. Published online 2021 May 14. doi: 10.1083/jcb.202007005

PMCID:: PMC8129793

Abstract Article PDF–6.5M

Select item 80704078.

Modeling Neoplastic Growth in Renal Cell Carcinoma and Polycystic Kidney Disease

Cassandra Millet-Boureima, Stephanie He, Thi Bich Uyen Le, Chiara Gamberi

Int J Mol Sci. 2021 Apr; 22(8): 3918. Published online 2021 Apr 10. doi: 10.3390/ijms22083918

PMCID:: PMC8070407

Abstract Article PDF–3.8M

Select item 78006059.

Polycomb and Trithorax Group Proteins: The Long Road from Mutations in Drosophila to Use in Medicine

D. A. Chetverina, D. V. Lomaev, M. M. Erokhin

Acta Naturae. 2020 Oct-Dec; 12(4): 66–85. doi: 10.32607/actanaturae.11090

PMCID:: PMC7800605

Abstract Article PDF–2.9M

Select item 768354010.

Polycomb group-mediated histone H2A monoubiquitination in epigenome regulation and nuclear processes

Haithem Barbour, Salima Daou, Michael Hendzel, El Bachir Affar

Nat Commun. 2020; 11: 5947. Published online 2020 Nov 23. doi: 10.1038/s41467-020-19722-9

PMCID:: PMC7683540

Abstract Article PDF–1.9M

Select item 766008711.

Molecular Regulation of the Polycomb Repressive-Deubiquitinase

Cameron J. Reddington, Matthias Fellner, Abigail E. Burgess, Peter D. Mace

Int J Mol Sci. 2020 Nov; 21(21): 7837. Published online 2020 Oct 22. doi: 10.3390/ijms21217837

PMCID:: PMC7660087

Abstract Article PDF–1.6M

Select item 696157812.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 640083213.

Regulation of Polycomb Repression by O-GlcNAcylation: Linking Nutrition to Epigenetic Reprogramming in Embryonic Development and Cancer

Amélie Decourcelle, Dominique Leprince, Vanessa Dehennaut

Front Endocrinol (Lausanne) 2019; 10: 117. Published online 2019 Feb 27. doi: 10.3389/fendo.2019.00117

PMCID:: PMC6400832

Abstract Article PDF–1.3M

Select item 619723714.

Monoubiquitination of ASXLs controls the deubiquitinase activity of the tumor suppressor BAP1

Salima Daou, Haithem Barbour, Oumaima Ahmed, Louis Masclef, Caroline Baril, Nadine Sen Nkwe, Daméhan Tchelougou, Maxime Uriarte, Eric Bonneil, Derek Ceccarelli, Nazar Mashtalir, Mika Tanji, Jean-Yves Masson, Pierre Thibault, Frank Sicheri, Haining Yang, Michele Carbone, Marc Therrien, El Bachir Affar

Nat Commun. 2018; 9: 4385. Published online 2018 Oct 22. doi: 10.1038/s41467-018-06854-2

PMCID:: PMC6197237

Abstract Article PDF–5.5M

Select item 615817215.

A bidentate Polycomb Repressive-Deubiquitinase complex is required for efficient activity on nucleosomes

Martina Foglizzo, Adam J. Middleton, Abigail E. Burgess, Jennifer M. Crowther, Renwick C. J. Dobson, James M. Murphy, Catherine L. Day, Peter D. Mace

Nat Commun. 2018; 9: 3932. Published online 2018 Sep 26. doi: 10.1038/s41467-018-06186-1

PMCID:: PMC6158172

Abstract Article PDF–3.4M

Select item 606519816.

Cyclin G and the Polycomb Repressive complexes PRC1 and PR-DUB cooperate for developmental stability

Delphine Dardalhon-Cuménal, Jérôme Deraze, Camille A. Dupont, Valérie Ribeiro, Anne Coléno-Costes, Juliette Pouch, Stéphane Le Crom, Hélène Thomassin, Vincent Debat, Neel B. Randsholt, Frédérique Peronnet

PLoS Genet. 2018 Jul; 14(7): e1007498. Published online 2018 Jul 11. doi: 10.1371/journal.pgen.1007498