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Select item 110264131.

Cdk8/CDK19 promotes mitochondrial fission through Drp1 phosphorylation and can phenotypically suppress pink1 deficiency in Drosophila

Jenny Zhe Liao, Hyung-lok Chung, Claire Shih, Kenneth Kin Lam Wong, Debdeep Dutta, Zelha Nil, Catherine Grace Burns, Oguz Kanca, Ye-Jin Park, Zhongyuan Zuo, Paul C. Marcogliese, Katherine Sew, Hugo J. Bellen, Esther M. Verheyen

Nat Commun. 2024; 15: 3326. Published online 2024 Apr 18. doi: 10.1038/s41467-024-47623-8

PMCID:: PMC11026413

Abstract Article PDF–18M

Select item 108477252.

Bone morphogenetic protein signaling: the pathway and its regulation

Takuya Akiyama, Laurel A Raftery, Kristi A Wharton

Genetics. 2024 Feb; 226(2): iyad200. Published online 2023 Dec 20. doi: 10.1093/genetics/iyad200

PMCID:: PMC10847725

Abstract Article PDF–6.8M

Select item 97025403.

Cdk8 attenuates lipogenesis by inhibiting SREBP-dependent transcription in Drosophila

Xiao Li, Meng Zhang, Mengmeng Liu, Tzu-Hao Liu, Rajitha-Udakara-Sampath Hemba-Waduge, Jun-Yuan Ji

Dis Model Mech. 2022 Nov 1; 15(11): dmm049650. Published online 2022 Nov 14. doi: 10.1242/dmm.049650

PMCID:: PMC9702540

Abstract Article

Select item 79772874.

Differential Requirements for Mediator Complex Subunits in Drosophila melanogaster Host Defense Against Fungal and Bacterial Pathogens

Chuqin Huang, Rui Xu, Samuel Liégeois, Di Chen, Zi Li, Dominique Ferrandon

Front Immunol. 2020; 11: 478958. Published online 2021 Mar 5. doi: 10.3389/fimmu.2020.478958

PMCID:: PMC7977287

Abstract Article PDF–2.3M

Select item 76486485.

A single-cell atlas and lineage analysis of the adult Drosophila ovary

Katja Rust, Lauren E. Byrnes, Kevin Shengyang Yu, Jason S. Park, Julie B. Sneddon, Aaron D. Tward, Todd G. Nystul

Nat Commun. 2020; 11: 5628. Published online 2020 Nov 6. doi: 10.1038/s41467-020-19361-0

Correction in:: Nat Commun. 2021; 12: 5951.

PMCID:: PMC7648648

Abstract Article PDF–6.1M

Select item 76171176.

Integrating animal development: how hormones and metabolism regulate developmental transitions and brain formation

Andreia C. Oliveira, Ana R. Rebelo, Catarina C.F. Homem

Dev Biol. Author manuscript; available in PMC 2024 Dec 9.

Published in final edited form as: Dev Biol. 2021 Jul 1; 475: 256–264. Published online 2021 Feb 4. doi: 10.1016/j.ydbio.2021.01.016

PMCID:: PMC7617117

Abstract Article PDF–1.0M

Select item 75216417.

Mediator complex subunit Med19 binds directly GATA transcription factors and is required with Med1 for GATA-driven gene regulation in vivo

Clément Immarigeon, Sandra Bernat-Fabre, Emmanuelle Guillou, Alexis Verger, Elodie Prince, Mohamed A. Benmedjahed, Adeline Payet, Marie Couralet, Didier Monte, Vincent Villeret, Henri-Marc Bourbon, Muriel Boube

J Biol Chem. 2020 Sep 25; 295(39): 13617–13629. Published online 2020 Jul 31. doi: 10.1074/jbc.RA120.013728

PMCID:: PMC7521641

Abstract Article PDF–3.0M

Select item 72826768.

The Mediator CDK8-Cyclin C complex modulates Dpp signaling in Drosophila by stimulating Mad-dependent transcription

Xiao Li, Mengmeng Liu, Xingjie Ren, Nicolas Loncle, Qun Wang, Rajitha-Udakara-Sampath Hemba-Waduge, Stephen H. Yu, Muriel Boube, Henri-Marc G. Bourbon, Jian-Quan Ni, Jun-Yuan Ji

PLoS Genet. 2020 May; 16(5): e1008832. Published online 2020 May 28. doi: 10.1371/journal.pgen.1008832

PMCID:: PMC7282676

Abstract Article PDF–4.0M

Select item 72139819.

Enhancer architecture sensitizes cell specific responses to Notch gene dose via a bind and discard mechanism

Yi Kuang, Ohad Golan, Kristina Preusse, Brittany Cain, Collin J Christensen, Joseph Salomone, Ian Campbell, FearGod V Okwubido-Williams, Matthew R Hass, Zhenyu Yuan, Nathanel Eafergan, Kenneth H Moberg, Rhett A Kovall, Raphael Kopan, David Sprinzak, Brian Gebelein

eLife. 2020; 9: e53659. Published online 2020 Apr 16. doi: 10.7554/eLife.53659

PMCID:: PMC7213981

Abstract Article PDF–3.4M

Select item 696157810.

CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans

Ping Wei, Wen Xue, Yun Zhao, Guang Ning, Jiwu Wang

Genome Res. 2020 Jan; 30(1): 95–106. doi: 10.1101/gr.250811.119

PMCID:: PMC6961578

Abstract Article PDF–3.6M

Select item 631960811.

Time-resolved mapping of genetic interactions to model rewiring of signaling pathways

Florian Heigwer, Christian Scheeder, Thilo Miersch, Barbara Schmitt, Claudia Blass, Mischan Vali Pour Jamnani, Michael Boutros

eLife. 2018; 7: e40174. Published online 2018 Dec 28. doi: 10.7554/eLife.40174

PMCID:: PMC6319608

Abstract Article PDF–3.4M

Select item 626385112.

CDK8 Mediates the Dietary Effects on Developmental Transition in Drosophila

Xinsheng Gao, Xiao-Jun Xie, Fu-Ning Hsu, Xiao Li, Mengmeng Liu, Rajitha-Udakara-Sampath Hemba-Waduge, Wu Xu, Jun-Yuan Ji

Dev Biol. Author manuscript; available in PMC 2019 Dec 15.

Published in final edited form as: Dev Biol. 2018 Dec 15; 444(2): 62–70. Published online 2018 Oct 21. doi: 10.1016/j.ydbio.2018.10.001

PMCID:: PMC6263851

Abstract Article PDF–2.0M

Select item 610078213.

The TORC1-regulated CPA complex rewires an RNA processing network to drive autophagy and metabolic reprogramming

Hong-Wen Tang, Yanhui Hu, Chiao-Lin Chen, Baolong Xia, Jonathan Zirin, Min Yuan, John M. Asara, Leonard Rabinow, Norbert Perrimon

Cell Metab. Author manuscript; available in PMC 2019 May 1.

Published in final edited form as: Cell Metab. 2018 May 1; 27(5): 1040–1054.e8. Published online 2018 Mar 29. doi: 10.1016/j.cmet.2018.02.023

PMCID:: PMC6100782

Abstract Article PDF–1.9M

Select item 570780514.

Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species

Piero Sanfilippo, Jiayu Wen, Eric C. Lai

Genome Biol. 2017; 18: 229. Published online 2017 Nov 30. doi: 10.1186/s13059-017-1358-0

PMCID:: PMC5707805

Abstract Article PDF–3.2M

Select item 568900215.

Transcription elongation rate has a tissue-specific impact on alternative cleavage and polyadenylation in Drosophila melanogaster

Xiaochuan Liu, Jaime Freitas, Dinghai Zheng, Marta S. Oliveira, Mainul Hoque, Torcato Martins, Telmo Henriques, Bin Tian, Alexandra Moreira

RNA. 2017 Dec; 23(12): 1807–1816. doi: 10.1261/rna.062661.117

PMCID:: PMC5689002

Abstract Article PDF–4.0M

Select item 531200416.

Seizure control through genetic and pharmacological manipulation of Pumilio in Drosophila: a key component of neuronal homeostasis

Wei-Hsiang Lin, Carlo N. G. Giachello, Richard A. Baines

Dis Model Mech. 2017 Feb 1; 10(2): 141–150. doi: 10.1242/dmm.027045

PMCID:: PMC5312004

Abstract Article

Select item 502748017.

Defining the essential function of FBP/KSRP proteins: Drosophila Psi interacts with the mediator complex to modulate MYC transcription and tissue growth

Linna Guo, Olga Zaysteva, Zuqin Nie, Naomi C. Mitchell, Jue Er Amanda Lee, Thomas Ware, Linda Parsons, Rodney Luwor, Gretchen Poortinga, Ross D. Hannan, David L. Levens, Leonie M. Quinn

Nucleic Acids Res. 2016 Sep 19; 44(16): 7646–7658. Published online 2016 May 20. doi: 10.1093/nar/gkw461

PMCID:: PMC5027480

Abstract Article PDF–5.6M

Select item 488965818.

mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster

Gildas Lepennetier, Francesco Catania

G3 (Bethesda) 2016 Jun; 6(6): 1617–1626. Published online 2016 Mar 28. doi: 10.1534/g3.116.029231

PMCID:: PMC4889658

Abstract Article PDF–1.5M

Select item 452833019.

Gene Model Annotations for Drosophila melanogaster: The Rule-Benders

Madeline A. Crosby, L. Sian Gramates, Gilberto dos Santos, Beverley B. Matthews, Susan E. St. Pierre, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, David B. Emmert, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1737–1749. Published online 2015 Jun 24. doi: 10.1534/g3.115.018937

PMCID:: PMC4528330

Abstract Article PDF–2.2M

Select item 452832920.

Gene Model Annotations for Drosophila melanogaster: Impact of High-Throughput Data

Beverley B. Matthews, Gilberto dos Santos, Madeline A. Crosby, David B. Emmert, Susan E. St. Pierre, L. Sian Gramates, Pinglei Zhou, Andrew J. Schroeder, Kathleen Falls, Victor Strelets, Susan M. Russo, William M. Gelbart, the FlyBase Consortium

G3 (Bethesda) 2015 Aug; 5(8): 1721–1736. Published online 2015 Jun 24. doi: 10.1534/g3.115.018929