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Select item 107845241.

Diabetic sensory neuropathy and insulin resistance are induced by loss of UCHL1 in Drosophila

Daewon Lee, Eunju Yoon, Su Jin Ham, Kunwoo Lee, Hansaem Jang, Daihn Woo, Da Hyun Lee, Sehyeon Kim, Sekyu Choi, Jongkyeong Chung

Nat Commun. 2024; 15: 468. Published online 2024 Jan 11. doi: 10.1038/s41467-024-44747-9

PMCID:: PMC10784524

Abstract Article PDF–4.8M

Select item 107551832.

Metabolomic analysis of Drosophila melanogaster larvae lacking pyruvate kinase

Yasaman Heidarian, Jason P Tourigny, Tess D Fasteen, Nader H Mahmoudzadeh, Alexander J Hurlburt, Travis Nemkov, Julie A Reisz, Angelo D’Alessandro, Jason M Tennessen

G3 (Bethesda) 2024 Jan; 14(1): jkad228. Published online 2023 Oct 4. doi: 10.1093/g3journal/jkad228

PMCID:: PMC10755183

Abstract Article PDF–2.9M

Select item 106821753.

PARP-1 is a transcriptional rheostat of metabolic and bivalent genes during development

Gbolahan Bamgbose, Alexei Tulin

Life Sci Alliance. 2024 Feb; 7(2): e202302369. Published online 2023 Nov 27. doi: 10.26508/lsa.202302369

PMCID:: PMC10682175

Abstract Article PDF–3.8M

Select item 105756294.

Chromatin and gene expression changes during female Drosophila germline stem cell development illuminate the biology of highly potent stem cells

Liang-Yu Pang, Steven DeLuca, Haolong Zhu, John M Urban, Allan C Spradling

eLife. 2023; 12: RP90509. Published online 2023 Oct 13. doi: 10.7554/eLife.90509

PMCID:: PMC10575629

Abstract Article PDF–6.3M

Select item 104276965.

REPTOR and CREBRF encode key regulators of muscle energy metabolism

Pedro Saavedra, Phillip A. Dumesic, Yanhui Hu, Elizabeth Filine, Patrick Jouandin, Richard Binari, Sarah E. Wilensky, Jonathan Rodiger, Haiyun Wang, Weihang Chen, Ying Liu, Bruce M. Spiegelman, Norbert Perrimon

Nat Commun. 2023; 14: 4943. Published online 2023 Aug 15. doi: 10.1038/s41467-023-40595-1

PMCID:: PMC10427696

Abstract Article PDF–6.5M

Select item 102497436.

Dietary Sugar Shifts Mitochondrial Metabolism and Small RNA Biogenesis in Sperm

Rashmi Ramesh, Signe Skog, Lovisa Örkenby, Unn Kugelberg, Daniel Nätt, Anita Öst

Antioxid Redox Signal. June 2023; 38(16): 1167–1183. Published online 2023 May 25. doi: 10.1089/ars.2022.0049

PMCID:: PMC10249743

Abstract Article PDF–1.3M

Select item 102090777.

Glycolytically impaired Drosophila glial cells fuel neural metabolism via β-oxidation

Ellen McMullen, Helen Hertenstein, Katrin Strassburger, Leon Deharde, Marko Brankatschk, Stefanie Schirmeier

Nat Commun. 2023; 14: 2996. Published online 2023 May 24. doi: 10.1038/s41467-023-38813-x

PMCID:: PMC10209077

Abstract Article PDF–1.1M

Select item 101916208.

Neuronal identity defines α-synuclein and tau toxicity

Roman Praschberger, Sabine Kuenen, Nils Schoovaerts, Natalie Kaempf, Jeevanjot Singh, Jasper Janssens, Jef Swerts, Eliana Nachman, Carles Calatayud, Stein Aerts, Suresh Poovathingal, Patrik Verstreken

Neuron. 2023 May 17; 111(10): 1577–1590.e11. doi: 10.1016/j.neuron.2023.02.033

PMCID:: PMC10191620

Abstract Article

Select item 101045489.

E2F regulation of the Phosphoglycerate kinase gene is functionally important in Drosophila development

Maria Paula Zappia, Yong-Jae Kwon, Anton Westacott, Isabel Liseth, Hyun Min Lee, Abul B. M. M. K. Islam, Jiyeon Kim, Maxim V. Frolov

Proc Natl Acad Sci U S A. 2023 Apr 11; 120(15): e2220770120. Published online 2023 Apr 3. doi: 10.1073/pnas.2220770120

PMCID:: PMC10104548

Abstract Article PDF–1.7M

Select item 1007891710.

A modERN resource: identification of Drosophila transcription factor candidate target genes using RNAi

William W Fisher, Ann S Hammonds, Richard Weiszmann, Benjamin W Booth, Louis Gevirtzman, Jaeda E J Patton, Connor A Kubo, Robert H Waterston, Susan E Celniker

Genetics. 2023 Apr; 223(4): iyad004. Published online 2023 Jan 19. doi: 10.1093/genetics/iyad004

PMCID:: PMC10078917

Abstract Article PDF–18M

Select item 999757011.

NDR kinase tricornered genetically interacts with Ccm3 and metabolic enzymes in Drosophila melanogaster tracheal development

Joshua Hudson, Sayantanee Paul, Alexey Veraksa, Amin Ghabrial, Kieran F Harvey, Carole Poon

G3 (Bethesda) 2023 Mar; 13(3): jkad013. Published online 2023 Jan 19. doi: 10.1093/g3journal/jkad013

PMCID:: PMC9997570

Abstract Article PDF–798K

Select item 952399712.

MBD5 and MBD6 stabilize the BAP1 complex and promote BAP1-dependent cancer

Natsumi Tsuboyama, Aileen Patricia Szczepanski, Zibo Zhao, Lu Wang

Genome Biol. 2022; 23: 206. Published online 2022 Sep 30. doi: 10.1186/s13059-022-02776-x

PMCID:: PMC9523997

Abstract Article PDF–6.9M

Select item 920942513.

Global stable-isotope tracing metabolomics reveals system-wide metabolic alternations in aging Drosophila

Ruohong Wang, Yandong Yin, Jingshu Li, Hongmiao Wang, Wanting Lv, Yang Gao, Tangci Wang, Yedan Zhong, Zhiwei Zhou, Yuping Cai, Xiaoyang Su, Nan Liu, Zheng-Jiang Zhu

Nat Commun. 2022; 13: 3518. Published online 2022 Jun 20. doi: 10.1038/s41467-022-31268-6

PMCID:: PMC9209425

Abstract Article PDF–2.4M

Select item 903727214.

The tobacco phosphatidylethanolamine-binding protein NtFT4 increases the lifespan of Drosophila melanogaster by interacting with the proteostasis network

Philip Känel, Gundula A. Noll, Katrin Schroedter, Elke Naffin, Julia Kronenberg, Franziska Busswinkel, Richard M. Twyman, Christian Klämbt, Dirk Prüfer

Aging (Albany NY) 2022 Apr 15; 14(7): 2989–3029. Published online 2022 Apr 8. doi: 10.18632/aging.204005

PMCID:: PMC9037272

Abstract Article PDF–10M

Select item 896152815.

Phenotyping of Drosophila Melanogaster—A Nutritional Perspective

Virginia Eickelberg, Kai Lüersen, Stefanie Staats, Gerald Rimbach

Biomolecules. 2022 Feb; 12(2): 221. Published online 2022 Jan 27. doi: 10.3390/biom12020221

PMCID:: PMC8961528

Abstract Article PDF–7.8M

Select item 882470116.

Liam C Hunt, Fabio Demontis

J Gerontol A Biol Sci Med Sci. 2022 Feb; 77(2): 259–267. Published online 2021 Sep 3. doi: 10.1093/gerona/glab260

PMCID:: PMC8824701

Abstract Article PDF–8.5M

Select item 866448617.

Genome-wide phenotypic RNAi screen in the Drosophila wing: phenotypic description of functional classes

Ana López-Varea, Patricia Vega-Cuesta, Ana Ruiz-Gómez, Cristina M Ostalé, Cristina Molnar, Covadonga F Hevia, Mercedes Martín, Maria F Organista, Jesus de Celis, Joaquín Culí, Nuria Esteban, Jose F de Celis

G3 (Bethesda) 2021 Dec; 11(12): jkab349. Published online 2021 Oct 2. doi: 10.1093/g3journal/jkab349

PMCID:: PMC8664486

Abstract Article PDF–3.1M

Select item 864520718.

In vivo proximity biotin ligation identifies the interactome of Egalitarian, a Dynein cargo adaptor

Frederick C. Baker, Hannah Neiswender, Rajalakshmi Veeranan-Karmegam, Graydon B. Gonsalvez

Development. 2021 Nov 15; 148(22): dev199935. Published online 2021 Nov 18. doi: 10.1242/dev.199935

PMCID:: PMC8645207

Abstract Article

Select item 853036319.

Metabolic gene regulation by Drosophila GATA transcription factor Grain

Krista Kokki, Nicole Lamichane, Anni I. Nieminen, Hanna Ruhanen, Jack Morikka, Marius Robciuc, Bohdana M. Rovenko, Essi Havula, Reijo Käkelä, Ville Hietakangas

PLoS Genet. 2021 Oct; 17(10): e1009855. Published online 2021 Oct 11. doi: 10.1371/journal.pgen.1009855