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Select item 111905731.

TBX3 is essential for establishment of the posterior boundary of anterior genes and upregulation of posterior genes together with HAND2 during the onset of limb bud development

Geoffrey Soussi, Ausra Girdziusaite, Shalu Jhanwar, Victorio Palacio, Marco Notaro, Rushikesh Sheth, Rolf Zeller, Aimée Zuniga

Development. 2024 Jun 1; 151(11): dev202722. Published online 2024 Jun 3. doi: 10.1242/dev.202722

PMCID:: PMC11190573

Abstract Article

Select item 90077372.

Compartmentalized metabolism supports midgestation mammalian development

Ashley Solmonson, Brandon Faubert, Wen Gu, Aparna Rao, Mitzy A. Cowdin, Ivan Menendez-Montes, Sherwin Kelekar, Thomas J. Rogers, Chunxiao Pan, Gerardo Guevara, Amy Tarangelo, Lauren G. Zacharias, Misty S. Martin-Sandoval, Duyen Do, Panayotis Pachnis, Dennis Dumesnil, Thomas P. Mathews, Alpaslan Tasdogan, An Pham, Ling Cai, Zhiyu Zhao, Min Ni, Ondine Cleaver, Hesham A. Sadek, Sean J. Morrison, Ralph J. DeBerardinis

Nature. 2022; 604(7905): 349–353. Published online 2022 Apr 6. doi: 10.1038/s41586-022-04557-9

PMCID:: PMC9007737

Abstract Article PDF–6.0M

Select item 82475453.

Cooperative Binding of ETS2 and NFAT Links Erk1/2 and Calcineurin Signaling in the Pathogenesis of Cardiac Hypertrophy

Yuxuan Luo, Nan Jiang, Herman I. May, Xiang Luo, Anwarul Ferdous, Gabriele G. Schiattarella, Guihao Chen, Qinfeng Li, Chao Li, Beverly A. Rothermel, Dingsheng Jiang, Sergio Lavandero, Thomas G. Gillette, Joseph A. Hill

Circulation. 2021 Jul 6; 144(1): 34–51. Published online 2021 Apr 6. doi: 10.1161/CIRCULATIONAHA.120.052384

PMCID:: PMC8247545

Abstract Article PDF–3.3M

Select item 82456324.

Ets-2 deletion in myeloid cells attenuates IL-1α-mediated inflammatory disease caused by a Ptpn6 point mutation

Sarang Tartey, Prajwal Gurung, Rajendra Karki, Amanda Burton, Paul Hertzog, Thirumala-Devi Kanneganti

Cell Mol Immunol. 2021 Jul; 18(7): 1798–1808. Published online 2020 Mar 19. doi: 10.1038/s41423-020-0398-7

PMCID:: PMC8245632

Abstract Article PDF–3.1M

Select item 80500535.

A novel tissue specific alternative splicing variant mitigates phenotypes in Ets2 frame-shift mutant models

Yuki Kishimoto, Iori Nishiura, Wataru Hirata, Shunsuke Yuri, Nami Yamamoto, Masahito Ikawa, Ayako Isotani

Sci Rep. 2021; 11: 8297. Published online 2021 Apr 15. doi: 10.1038/s41598-021-87751-5

PMCID:: PMC8050053

Abstract Article PDF–1.3M

Select item 69143886.

Ets2 suppresses inflammatory cytokines through MAPK/NF-κB signaling and directly binds to the IL-6 promoter in macrophages

Xianwei Ma, Zhengyu Jiang, Na Li, Wei Jiang, Peng Gao, Mingjin Yang, Xiya Yu, Guifang Wang, Yan Zhang

Aging (Albany NY) 2019 Nov 30; 11(22): 10610–10625. Published online 2019 Nov 27. doi: 10.18632/aging.102480

PMCID:: PMC6914388

Abstract Article PDF–3.9M

Select item 68543737.

EGF suppresses the expression of miR-124a in pancreatic β cell lines via ETS2 activation through the MEK and PI3K signaling pathways

Lin Yang, Yuansen Zhu, Delin Kong, Jiawei Gong, Wen Yu, Yang Liang, Yuzhe Nie, Chun-Bo Teng

Int J Biol Sci. 2019; 15(12): 2561–2575. Published online 2019 Sep 7. doi: 10.7150/ijbs.34985

PMCID:: PMC6854373

Abstract Article PDF–2.3M

Select item 56950868.

Integrative genome analysis of somatic p53 mutant osteosarcomas identifies Ets2-dependent regulation of small nucleolar RNAs by mutant p53 protein

Rasoul Pourebrahim, Yun Zhang, Bin Liu, Ruli Gao, Shunbin Xiong, Patrick P. Lin, Mark J. McArthur, Michael C. Ostrowski, Guillermina Lozano

Genes Dev. 2017 Sep 15; 31(18): 1847–1857. doi: 10.1101/gad.304972.117

PMCID:: PMC5695086

Abstract Article PDF–7.7M

Select item 55680749.

Articular cartilage endurance and resistance to osteoarthritic changes require transcription factor Erg

Yoichi Ohta, Takahiro Okabe, Colleen Larmour, Agnese Di Rocco, Marijke Maijenburg, Amanda Phillips, Nancy A. Speck, Shigeyuki Wakitani, Takashi Nakamura, Yoshihiko Yamada, Motomi Enomoto-Iwamoto, Maurizio Pacifici, Masahiro Iwamoto

Arthritis Rheumatol. Author manuscript; available in PMC 2017 Aug 23.

Published in final edited form as: Arthritis Rheumatol. 2015 Oct; 67(10): 2679–2690. doi: 10.1002/art.39243

PMCID:: PMC5568074

Abstract Article PDF–2.6M

Select item 554031810.

ARID3A is required for mammalian placenta development

Catherine Rhee, Melissa Edwards, Christine Dang, June Harris, Mark Brown, Jonghwan Kim, Haley O Tucker

Dev Biol. Author manuscript; available in PMC 2017 Aug 2.

Published in final edited form as: Dev Biol. 2017 Feb 15; 422(2): 83–91. Published online 2016 Dec 11. doi: 10.1016/j.ydbio.2016.12.003

PMCID:: PMC5540318

Abstract Article PDF–2.0M

Select item 549749511.

Molecular checkpoint decisions made by subverted vascular niche transform indolent tumor cells into chemoresistant cancer stem cells

Zhongwei Cao, Joseph M Scandura, Giorgio G. Inghirami, Koji Shido, Bi-Sen Ding, Shahin Rafii

Cancer Cell. Author manuscript; available in PMC 2017 Jul 5.

Published in final edited form as: Cancer Cell. 2017 Jan 9; 31(1): 110–126. Published online 2016 Dec 15. doi: 10.1016/j.ccell.2016.11.010

PMCID:: PMC5497495

Abstract Article PDF–5.0M

Select item 503186712.

Stromal ETS2 Regulates Chemokine Production and Immune Cell Recruitment during Acinar-to-Ductal Metaplasia

Jason R. Pitarresi, Xin Liu, Sudarshana M. Sharma, Maria C. Cuitiño, Raleigh D. Kladney, Thomas A. Mace, Sydney Donohue, Sunayana G. Nayak, Chunjing Qu, James Lee, Sarah A. Woelke, Stefan Trela, Kyle LaPak, Lianbo Yu, Joseph McElroy, Thomas J. Rosol, Reena Shakya, Thomas Ludwig, Gregory B. Lesinski, Soledad A. Fernandez, Stephen F. Konieczny, Gustavo Leone, Jinghai Wu, Michael C. Ostrowski

Neoplasia. 2016 Sep; 18(9): 541–552. Published online 2016 Sep 20. doi: 10.1016/j.neo.2016.07.006

PMCID:: PMC5031867

Abstract Article PDF–3.3M

Select item 487343513.

Deletion of interstitial genes between TMPRSS2 and ERG promotes prostate cancer progression

Douglas E. Linn, Kathryn L. Penney, Roderick T. Bronson, Lorelei A. Mucci, Zhe Li

Cancer Res. Author manuscript; available in PMC 2017 Apr 1.

Published in final edited form as: Cancer Res. 2016 Apr 1; 76(7): 1869–1881. Published online 2016 Feb 15. doi: 10.1158/0008-5472.CAN-15-1911

PMCID:: PMC4873435

Abstract Article PDF–2.3M

Select item 442804514.

Induction of hematopoietic and endothelial cell program orchestrated by ETS transcription factor ER71/ETV2

Fang Liu, Daofeng Li, Yik Yeung Lawrence Yu, Inyoung Kang, Min-Ji Cha, Ju Young Kim, Changwon Park, Dennis K Watson, Ting Wang, Kyunghee Choi

EMBO Rep. 2015 May; 16(5): 654–669. Published online 2015 Mar 23. doi: 10.15252/embr.201439939

PMCID:: PMC4428045

Abstract Article PDF–4.1M

Select item 436947315.

CSF1-ETS2 Induced microRNA in Myeloid Cells Promote Metastatic Tumor Growth

Haritha Mathsyaraja, Katie Thies, David A. Taffany, Clayton Deighan, Tom Liu, Lianbo Yu, Soledad A. Fernandez, Charles Shapiro, Jose Otero, Cynthia Timmers, Maryam B. Lustberg, Jeffrey Chalmers, Gustavo Leone, Michael C. Ostrowski

Oncogene. Author manuscript; available in PMC 2016 Jan 1.

Published in final edited form as: Oncogene. 2015 Jul; 34(28): 3651–3661. Published online 2014 Sep 22. doi: 10.1038/onc.2014.294

PMCID:: PMC4369473

Abstract Article PDF–1.7M

Select item 435727516.

HAND2 Targets Define a Network of Transcriptional Regulators that Compartmentalize the Early Limb Bud Mesenchyme

Marco Osterwalder, Dario Speziale, Malak Shoukry, Rajiv Mohan, Robert Ivanek, Manuel Kohler, Christian Beisel, Xiaohui Wen, Suzie J. Scales, Vincent M. Christoffels, Axel Visel, Javier Lopez-Rios, Rolf Zeller

Dev Cell. Author manuscript; available in PMC 2015 Nov 10.

Published in final edited form as: Dev Cell. 2014 Nov 10; 31(3): 345–357. Published online 2014 Nov 10. doi: 10.1016/j.devcel.2014.09.018

PMCID:: PMC4357275

Abstract Article PDF–3.1M

Select item 431955917.

A high resolution spatiotemporal atlas of gene expression of the developing mouse brain

Carol L. Thompson, Lydia Ng, Vilas Menon, Salvador Martinez, Chang-Kyu Lee, Katie Glattfelder, Susan M. Sunkin, Alex Henry, Christopher Lau, Chinh Dang, Raquel Garcia-Lopez, Almudena Martinez-Ferre, Ana Pombero, John L.R. Rubenstein, Wayne B. Wakeman, John Hohmann, Nick Dee, Andrew J. Sodt, Rob Young, Kimberly Smith, Thuc-Nghi Nguyen, Jolene Kidney, Leonard Kuan, Andreas Jeromin, Ajamete Kaykas, Jeremy Miller, Damon Page, Geri Orta, Amy Bernard, Zackery Riley, Simon Smith, Paul Wohnoutka, Mike Hawrylycz, Luis Puelles, Allan R. Jones

Neuron. Author manuscript; available in PMC 2015 Jul 16.

Published in final edited form as: Neuron. 2014 Jul 16; 83(2): 309–323. Published online 2014 Jun 19. doi: 10.1016/j.neuron.2014.05.033

PMCID:: PMC4319559

Abstract Article PDF–3.0M

Select item 408072218.

Fli1 Acts Downstream of Etv2 to Govern Cell Survival and Vascular Homeostasis via Positive Autoregulation

Md J. Abedin, Annie Nguyen, Nan Jiang, Cameron E. Perry, John M. Shelton, Dennis K. Watson, Anwarul Ferdous

Circ Res. Author manuscript; available in PMC 2015 May 23.

Published in final edited form as: Circ Res. 2014 May 23; 114(11): 1690–1699. Published online 2014 Apr 11. doi: 10.1161/CIRCRESAHA.1134303145

PMCID:: PMC4080722

Abstract Article PDF–1.7M

Select item 407262719.

MicroRNA 17-92 Cluster Mediates ETS1 and ETS2-Dependent RAS-Oncogenic Transformation

Mohamed Kabbout, Duaa Dakhlallah, Sudarshana Sharma, Agnieszka Bronisz, Ruchika Srinivasan, Melissa Piper, Clay B. Marsh, Michael C. Ostrowski

PLoS One. 2014; 9(6): e100693. Published online 2014 Jun 26. doi: 10.1371/journal.pone.0100693

PMCID:: PMC4072627

Abstract Article PDF–1.6M

Select item 392429420.

The Role of Ets2 Transcription Factor in the Induction of MicroRNA-155 (miR-155) by Lipopolysaccharide and Its Targeting by Interleukin-10

Susan R. Quinn, Niamh E. Mangan, Brian E. Caffrey, Michael P. Gantier, Bryan R. G. Williams, Paul J. Hertzog, Claire E. McCoy, Luke A. J. O'Neill

J Biol Chem. 2014 Feb 14; 289(7): 4316–4325. Published online 2013 Dec 20. doi: 10.1074/jbc.M113.522730

PMCID:: PMC3924294

Abstract Article PDF–1.2M

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