U.S. flag

An official website of the United States government

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Links from GEO Profiles

Items: 1 to 20 of 72

1.
RPA guides UNG to uracil in ssDNA to facilitate antibody class switching and repair of mutagenic uracil at the replication fork
Abdul B Hayran, Nina B Liabakk, Per A Aas, Anna Kusnierczyk, Cathrine B Vågbø, Antonio Sarno, Tobias S Iveland, Konika Chawla, Astrid Zahn, Javier M Di Noia, Geir Slupphaug, Bodil Kavli
Nucleic Acids Res. 2024 Jan 25; 52(2): 784–800. Published online 2023 Nov 24. doi: 10.1093/nar/gkad1115
PMCID:
PMC10810282
AbstractArticlePDF–2.0M
2.
FAM72A antagonizes UNG2 to promote mutagenic repair during antibody maturation
Yuqing Feng, Conglei Li, Jessica A. Stewart, Philip Barbulescu, Noé Seija Desivo, Alejandro Álvarez-Quilón, Rossanna C. Pezo, Madusha L. W. Perera, Katherine Chan, Amy Hin Yan Tong, Rukshana Mohamad-Ramshan, Maribel Berru, Diana Nakib, Gavin Li, Gholam Ali Kardar, James R. Carlyle, Jason Moffat, Daniel Durocher, Javier M. Di Noia, Ashok S. Bhagwat, Alberto Martin
Nature. Author manuscript; available in PMC 2022 Aug 30.
Published in final edited form as: Nature. 2021 Dec; 600(7888): 324–328. Published online 2021 Nov 24. doi: 10.1038/s41586-021-04144-4
PMCID:
PMC9425297
AbstractArticlePDF–4.9M
3.
Interplay between UNG and AID governs intratumoral heterogeneity in mature B cell lymphoma
Pilar Delgado, Ángel F. Álvarez-Prado, Ester Marina-Zárate, Isora V. Sernandez, Sonia M. Mur, Jorge de la Barrera, Fátima Sanchez-Cabo, Marta Cañamero, Antonio de Molina, Laura Belver, Virginia G. de Yébenes, Almudena R. Ramiro
PLoS Genet. 2020 Dec; 16(12): e1008960. Published online 2020 Dec 23. doi: 10.1371/journal.pgen.1008960
PMCID:
PMC7790409
AbstractArticlePDF–4.0M
4.
Impact of HIV-1 Vpr manipulation of the DNA repair enzyme UNG2 on B lymphocyte class switch recombination
Patrick Eldin, Sophie Péron, Anastasia Galashevskaya, Nicolas Denis-Lagache, Michel Cogné, Geir Slupphaug, Laurence Briant
J Transl Med. 2020; 18: 310. Published online 2020 Aug 10. doi: 10.1186/s12967-020-02478-7
PMCID:
PMC7418440
AbstractArticlePDF–1.6M
5.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
6.
Generation of a Mouse Model Lacking the Non-Homologous End-Joining Factor Mri/Cyren
Sergio Castañeda-Zegarra, Camilla Huse, Øystein Røsand, Antonio Sarno, Mengtan Xing, Raquel Gago-Fuentes, Qindong Zhang, Amin Alirezaylavasani, Julia Werner, Ping Ji, Nina-Beate Liabakk, Wei Wang, Magnar Bjørås, Valentyn Oksenych
Biomolecules. 2019 Dec; 9(12): 798. Published online 2019 Nov 28. doi: 10.3390/biom9120798
PMCID:
PMC6995585
AbstractArticlePDF–1.6M
7.
AID phosphorylation regulates mismatch repair-dependent class switch recombination and affinity maturation
Jee Eun Choi, Allysia J. Matthews, Genesis Michel, Bao Q. Vuong
J Immunol. Author manuscript; available in PMC 2021 Jan 1.
Published in final edited form as: J Immunol. 2020 Jan 1; 204(1): 13–22. Published online 2019 Nov 22. doi: 10.4049/jimmunol.1900809
PMCID:
PMC6920541
AbstractArticlePDF–1.6M
8.
Uracil–DNA glycosylase UNG1 isoform variant supports class switch recombination and repairs nuclear genomic uracil
Antonio Sarno, Marie Lundbæk, Nina Beate Liabakk, Per Arne Aas, Robin Mjelle, Lars Hagen, Mirta M L Sousa, Hans E Krokan, Bodil Kavli
Nucleic Acids Res. 2019 May 21; 47(9): 4569–4585. Published online 2019 Mar 6. doi: 10.1093/nar/gkz145
PMCID:
PMC6511853
AbstractArticlePDF–2.2M
9.
DSB structure impacts DNA recombination leading to class switching and chromosomal translocations in human B cells
Clare C. So, Alberto Martin
PLoS Genet. 2019 Apr; 15(4): e1008101. Published online 2019 Apr 4. doi: 10.1371/journal.pgen.1008101
PMCID:
PMC6467426
AbstractArticlePDF–3.3M
10.
DNA breaks in Ig V regions are predominantly single-stranded and are generated by UNG and MSH6 DNA repair pathways
Kimberly J. Zanotti, Robert W. Maul, William Yang, Patricia J. Gearhart
J Immunol. Author manuscript; available in PMC 2020 Mar 1.
Published in final edited form as: J Immunol. 2019 Mar 1; 202(5): 1573–1581. Published online 2019 Jan 21. doi: 10.4049/jimmunol.1801183
PMCID:
PMC6382588
AbstractArticlePDF–1.5M
11.
Uracil-DNA glycosylase is not implicated in the choice of the DNA repair pathway during B-cell class switch recombination
Nour Ghazzaui, Hussein Issaoui, Alexis Saintamand, Yves Denizot, François Boyer
Cell Mol Immunol. 2019 Jan; 16(1): 93–95. Published online 2018 May 7. doi: 10.1038/s41423-018-0034-y
PMCID:
PMC6318330
ArticlePDF–700K
12.
A licensing step links AID to transcription elongation for mutagenesis in B cells
Stephen P. Methot, Ludivine C. Litzler, Poorani Ganesh Subramani, Anil K. Eranki, Heather Fifield, Anne-Marie Patenaude, Julian C. Gilmore, Gabriel E. Santiago, Halil Bagci, Jean-François Côté, Mani Larijani, Ramiro E. Verdun, Javier M. Di Noia
Nat Commun. 2018; 9: 1248. Published online 2018 Mar 28. doi: 10.1038/s41467-018-03387-6
PMCID:
PMC5871760
AbstractArticlePDF–3.9M
13.
Phosphorylation promotes activation-induced cytidine deaminase activity at the Myc oncogene
Yunxiang Mu, Monika A. Zelazowska, Kevin M. McBride
J Exp Med. 2017 Dec 4; 214(12): 3543–3552. doi: 10.1084/jem.20170468
PMCID:
PMC5716038
AbstractArticlePDF–1.3M
14.
Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development
Elisabeth A. Rutledge, Jean-Denis Benazet, Andrew P. McMahon
Development. 2017 Sep 1; 144(17): 3177–3188. doi: 10.1242/dev.149112
PMCID:
PMC5611955
AbstractArticle
15.
Uracil Accumulation and Mutagenesis Dominated by Cytosine Deamination in CpG Dinucleotides in Mice Lacking UNG and SMUG1
Lene Alsøe, Antonio Sarno, Sergio Carracedo, Diana Domanska, Felix Dingler, Lisa Lirussi, Tanima SenGupta, Nuriye Basdag Tekin, Laure Jobert, Ludmil B. Alexandrov, Anastasia Galashevskaya, Cristina Rada, Geir Kjetil Sandve, Torbjørn Rognes, Hans E. Krokan, Hilde Nilsen
Sci Rep. 2017; 7: 7199. Published online 2017 Aug 3. doi: 10.1038/s41598-017-07314-5
PMCID:
PMC5543110
AbstractArticlePDF–4.3M
16.
Pms2 and uracil-DNA glycosylases act jointly in the mismatch repair pathway to generate Ig gene mutations at A-T base pairs
Giulia Girelli Zubani, Marija Zivojnovic, Annie De Smet, Olivier Albagli-Curiel, François Huetz, Jean-Claude Weill, Claude-Agnès Reynaud, Sébastien Storck
J Exp Med. 2017 Apr 3; 214(4): 1169–1180. doi: 10.1084/jem.20161576
PMCID:
PMC5379981
AbstractArticlePDF–1.4M
17.
The cell cycle restricts activation-induced cytidine deaminase activity to early G1
Qiao Wang, Kyong-Rim Kieffer-Kwon, Thiago Y. Oliveira, Christian T. Mayer, Kaihui Yao, Joy Pai, Zhen Cao, Marei Dose, Rafael Casellas, Mila Jankovic, Michel C. Nussenzweig, Davide F. Robbiani
J Exp Med. 2017 Jan; 214(1): 49–58. doi: 10.1084/jem.20161649
PMCID:
PMC5206505
AbstractArticlePDF–2.0M
18.
UNG protects B cells from AID-induced telomere loss
Elena M. Cortizas, Astrid Zahn, Shiva Safavi, Joseph A. Reed, Francisco Vega, Javier M. Di Noia, Ramiro E. Verdun
J Exp Med. 2016 Oct 17; 213(11): 2459–2472. doi: 10.1084/jem.20160635
PMCID:
PMC5068241
AbstractArticlePDF–2.8M
19.
AID-associated DNA repair pathways regulate malignant transformation in a murine model of BCL6-driven diffuse large B-cell lymphoma
Xiwen Gu, Carmen J. Booth, Zongzhi Liu, Matthew P. Strout
Blood. 2016 Jan 7; 127(1): 102–112. Prepublished online 2015 Sep 18. doi: 10.1182/blood-2015-02-628164
PMCID:
PMC4705602
AbstractArticle
20.
Uracil-DNA Glycosylase UNG Promotes Tet-mediated DNA Demethylation
Jian-Huang Xue, Gui-Fang Xu, Tian-Peng Gu, Guo-Dong Chen, Bin-Bin Han, Zhi-Mei Xu, Magnar Bjørås, Hans E. Krokan, Guo-Liang Xu, Ya-Rui Du
J Biol Chem. 2016 Jan 8; 291(2): 731–738. Published online 2015 Nov 30. doi: 10.1074/jbc.M115.693861
PMCID:
PMC4705393
AbstractArticlePDF–1.9M

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Filter your results:

Find related data

Recent activity

Clear Turn Off Turn On

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
You are here: NCBI > Literature > PubMed Central (PMC)
Support Center