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Items: 1 to 20 of 36

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
The PRAK-NRF2 axis promotes the differentiation of Th17 cells by mediating the redox homeostasis and glycolysis
Ziheng Zhao, Yan Wang, Yuhan Gao, Yurong Ju, Ye Zhao, Zhaofei Wu, Shuaixin Gao, Boyang Zhang, Xuewen Pang, Yu Zhang, Wei Wang
Proc Natl Acad Sci U S A. 2023 May 9; 120(19): e2212613120. Published online 2023 May 1. doi: 10.1073/pnas.2212613120
PMCID:
PMC10175746
AbstractArticlePDF–4.0M
3.
MAPKAPK5-AS1 drives the progression of hepatocellular carcinoma via regulating miR-429/ZEB1 axis
Zongqing Peng, Xinhua Ouyang, Yexing Wang, Qiming Fan
BMC Mol Cell Biol. 2022; 23: 21. Published online 2022 Apr 25. doi: 10.1186/s12860-022-00420-x
PMCID:
PMC9036786
AbstractArticlePDF–7.4M
4.
The Essential Role of PRAK in Preserving Cardiac Function and Insulin Resistance in High-Fat Diet-Induced Diabetes
Jianfeng Du, Yu Tina Zhao, Hao Wang, Ling X. Zhang, Gangjian Qin, Shougang Zhuang, Marshall Kadin, Y. Eugene Chin, Paul Y. Liu, Ting C. Zhao
Int J Mol Sci. 2021 Aug; 22(15): 7995. Published online 2021 Jul 27. doi: 10.3390/ijms22157995
PMCID:
PMC8347374
AbstractArticlePDF–3.3M
5.
MK5 haplodeficiency decreases collagen deposition and scar size during post-myocardial infarction wound repair
Sherin Ali Nawaito, Pramod Sahadevan, Marie-Élaine Clavet-Lanthier, Philippe Pouliot, Fatiha Sahmi, Yanfen Shi, Marc-Antoine Gillis, Frederic Lesage, Matthias Gaestel, Martin G. Sirois, Angelo Calderone, Jean-Claude Tardif, Bruce G. Allen
Am J Physiol Heart Circ Physiol. 2019 Jun 1; 316(6): H1281–H1296. Published online 2019 Mar 22. doi: 10.1152/ajpheart.00532.2017
Correction in:
Am J Physiol Heart Circ Physiol. 2021 Jul 1; 321(1): H161.
PMCID:
PMC8285621
AbstractArticle
6.
PRAK Promotes the Pathogen Clearance by Macrophage Through Regulating Autophagy and Inflammasome Activation
Ligu Mi, Yan Wang, Hui Xu, Yu Wang, Jia Wu, Hui Dai, Yu Zhang
Front Immunol. 2021; 12: 618561. Published online 2021 Apr 16. doi: 10.3389/fimmu.2021.618561
PMCID:
PMC8085562
AbstractArticlePDF–4.6M
7.
The essential role of PRAK in tumor metastasis and its therapeutic potential
Yuqing Wang, Wei Wang, Haoming Wu, Yu Zhou, Xiaodan Qin, Yan Wang, Jia Wu, Xiu-Yuan Sun, Yan Yang, Hui Xu, Xiaoping Qian, Xuewen Pang, Yan Li, Zhiqian Zhang, Jiahuai Han, Yu Zhang
Nat Commun. 2021; 12: 1736. Published online 2021 Mar 19. doi: 10.1038/s41467-021-21993-9
PMCID:
PMC7979731
AbstractArticlePDF–3.0M
8.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
9.
p38-Regulated/activated protein kinase plays a pivotal role in protecting heart against ischemia-reperfusion injury and preserving cardiac performance
Yu Tina Zhao, Jianfeng Du, Naohiro Yano, Hao Wang, Jianguo Wang, Patrycja M. Dubielecka, Ling X. Zhang, Gangjian Qin, Shougang Zhuang, Paul Y. Liu, Y. Eugene Chin, Ting C. Zhao
Am J Physiol Cell Physiol. 2019 Sep 1; 317(3): C525–C533. Published online 2019 Jul 10. doi: 10.1152/ajpcell.00122.2019
PMCID:
PMC6766622
AbstractArticle
10.
PRAK Is Required for the Formation of Neutrophil Extracellular Traps
Yan Wang, Yuqing Wang, Jia Wu, Chen Liu, Yu Zhou, Ligu Mi, Yu Zhang, Wei Wang
Front Immunol. 2019; 10: 1252. Published online 2019 Jun 4. doi: 10.3389/fimmu.2019.01252
PMCID:
PMC6559312
AbstractArticlePDF–2.6M
11.
The transcriptional regulation and cell-specific expression of the MAPK-activated protein kinase MK5
Nancy Gerits, Alexey Shiryaev, Sergiy Kostenko, Helle Klenow, Olga Shiryaeva, Mona Johannessen, Ugo Moens
Cell Mol Biol Lett. 2009 Dec; 14(4): 548–574. Published online 2009 May 30. doi: 10.2478/s11658-009-0020-6
PMCID:
PMC6276003
SummaryPDF–14M
12.
Comparative Analysis of Two Gene-Targeting Approaches Challenges the Tumor-Suppressive Role of the Protein Kinase MK5/PRAK
Natalia Ronkina, Claus Johansen, Lisa Bohlmann, Juri Lafera, Manoj B. Menon, Christopher Tiedje, Kathrin Laaß, Benjamin E. Turk, Lars Iversen, Alexey Kotlyarov, Matthias Gaestel
PLoS One. 2015; 10(8): e0136138. Published online 2015 Aug 21. doi: 10.1371/journal.pone.0136138
PMCID:
PMC4546416
AbstractArticlePDF–2.9M
13.
Positive selection in the adhesion domain of Mus sperm Adam genes through gene duplications and function-driven gene complex formations
Phil Grayson, Alberto Civetta
BMC Evol Biol. 2013; 13: 217. Published online 2013 Sep 30. doi: 10.1186/1471-2148-13-217
PMCID:
PMC3849967
AbstractArticlePDF–252K
14.
MK5 activates Rag transcription via Foxo1 in developing B cells
Kwan T. Chow, Greg A. Timblin, Sarah M. McWhirter, Mark S. Schlissel
J Exp Med. 2013 Jul 29; 210(8): 1621–1634. doi: 10.1084/jem.20130498
PMCID:
PMC3727319
AbstractArticlePDF–2.2M
15.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
16.
Sequence and structural analyses of nuclear export signals in the NESdb database
Darui Xu, Alicia Farmer, Garen Collett, Nick V. Grishin, Yuh Min Chook
Mol Biol Cell. 2012 Sep 15; 23(18): 3677–3693. doi: 10.1091/mbc.E12-01-0046
PMCID:
PMC3442415
AbstractArticlePDF–1.8M
17.
Rottlerin-Mediated Inhibition of Chlamydia trachomatis Growth and Uptake of Sphingolipids Is Independent of p38-Regulated/Activated Protein Kinase (PRAK)
Lei Lei, Zhongyu Li, Guangming Zhong
PLoS One. 2012; 7(9): e44733. Published online 2012 Sep 7. doi: 10.1371/journal.pone.0044733
PMCID:
PMC3436872
AbstractArticlePDF–2.5M
18.
The Extracellular Signal-Regulated Kinase 3 (Mitogen-Activated Protein Kinase 6 [MAPK6])–MAPK-Activated Protein Kinase 5 Signaling Complex Regulates Septin Function and Dendrite Morphology
Frank Brand, Stefanie Schumacher, Shashi Kant, Manoj B. Menon, Ruth Simon, Benjamin Turgeon, Stefan Britsch, Sylvain Meloche, Matthias Gaestel, Alexey Kotlyarov
Mol Cell Biol. 2012 Jul; 32(13): 2467–2478. doi: 10.1128/MCB.06633-11
PMCID:
PMC3434500
AbstractArticlePDF–2.5M
19.
Characterization of the expression and regulation of MK5 in the murine ventricular myocardium
Dharmendra Dingar, Marie-Josée Benoit, Aida M. Mamarbachi, Louis R. Villeneuve, Marc-Antoine Gillis, Scott Grandy, Matthias Gaestel, Celine Fiset, Bruce G. Allen
Cell Signal. Author manuscript; available in PMC 2012 Aug 9.
Published in final edited form as: Cell Signal. 2010 Jul; 22(7): 1063–1075. Published online 2010 Mar 7. doi: 10.1016/j.cellsig.2010.02.009
PMCID:
PMC3415464
AbstractArticlePDF–2.2M
20.
PRAK suppresses oncogenic ras-induced hematopoietic cancer development by antagonizing the JNK pathway
Naoto Yoshizuka, Maoyi Lai, Rong Liao, Ryan Cook, Changchun Xiao, Jiahuai Han, Peiqing Sun
Mol Cancer Res. Author manuscript; available in PMC 2013 Jun 4.
Published in final edited form as: Mol Cancer Res. 2012 Jun; 10(6): 810–820. Published online 2012 Jun 4. doi: 10.1158/1541-7786.MCR-11-0576
PMCID:
PMC3378811
AbstractArticlePDF–2.4M

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