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Items: 1 to 20 of 21

1.
The Posttraumatic Increase of the Adhesion GPCR EMR2/ADGRE2 on Circulating Neutrophils Is Not Related to Injury Severity
Leyu Zheng, Moujie Rang, Carolin Fuchs, Annette Keß, Mandy Wunsch, Julia Hentschel, Cheng-Chih Hsiao, Christian Kleber, Georg Osterhoff, Gabriela Aust
Cells. 2023 Nov; 12(22): 2657. Published online 2023 Nov 20. doi: 10.3390/cells12222657
PMCID:
PMC10670733
AbstractArticlePDF–2.1M
2.
Assessment of community efforts to advance network-based prediction of protein–protein interactions
Xu-Wen Wang, Lorenzo Madeddu, Kerstin Spirohn, Leonardo Martini, Adriano Fazzone, Luca Becchetti, Thomas P. Wytock, István A. Kovács, Olivér M. Balogh, Bettina Benczik, Mátyás Pétervári, Bence Ágg, Péter Ferdinandy, Loan Vulliard, Jörg Menche, Stefania Colonnese, Manuela Petti, Gaetano Scarano, Francesca Cuomo, Tong Hao, Florent Laval, Luc Willems, Jean-Claude Twizere, Marc Vidal, Michael A. Calderwood, Enrico Petrillo, Albert-László Barabási, Edwin K. Silverman, Joseph Loscalzo, Paola Velardi, Yang-Yu Liu
Nat Commun. 2023; 14: 1582. Published online 2023 Mar 22. doi: 10.1038/s41467-023-37079-7
PMCID:
PMC10033937
AbstractArticlePDF–1.5M
3.
ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1
Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen
Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119
PMCID:
PMC9231623
AbstractArticlePDF–6.0M
4.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
5.
Stimulation of Vibratory Urticaria-Associated Adhesion-GPCR, EMR2/ADGRE2, Triggers the NLRP3 Inflammasome Activation Signal in Human Monocytes
Kuan-Yu I, Wen-Yi Tseng, Wen-Chih Wang, Siamon Gordon, Kwai-Fong Ng, Hsi-Hsien Lin
Front Immunol. 2020; 11: 602016. Published online 2021 Jan 8. doi: 10.3389/fimmu.2020.602016
PMCID:
PMC7820815
AbstractArticlePDF–3.5M
6.
CRITICAL SIGNALING EVENTS IN THE MECHANOACTIVATION OF HUMAN MAST CELLS VIA P.C492Y-ADGRE2
Andrea N. Naranjo, Geethani Bandara, Yun Bai, Margery G. Smelkinson, Araceli Tobío, Hirsh D. Komarow, Steven E. Boyden, Daniel L. Kastner, Dean D. Metcalfe, Ana Olivera
J Invest Dermatol. Author manuscript; available in PMC 2021 Nov 1.
Published in final edited form as: J Invest Dermatol. 2020 Nov; 140(11): 2210–2220.e5. Published online 2020 Mar 25. doi: 10.1016/j.jid.2020.03.936
PMCID:
PMC7529699
AbstractArticlePDF–2.4M
7.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
8.
G Protein-Coupling of Adhesion GPCRs ADGRE2/EMR2 and ADGRE5/CD97, and Activation of G Protein Signalling by an Anti-EMR2 Antibody
Nisha Bhudia, Sapna Desai, Natalie King, Nicolas Ancellin, Didier Grillot, Ashley A. Barnes, Simon J. Dowell
Sci Rep. 2020; 10: 1004. Published online 2020 Jan 22. doi: 10.1038/s41598-020-57989-6
Correction in:
Sci Rep. 2020; 10: 5097.
PMCID:
PMC6976652
AbstractArticlePDF–1.5M
9.
Serum FHR1 binding to necrotic-type cells activates monocytic inflammasome and marks necrotic sites in vasculopathies
Sarah Irmscher, Silke R. Brix, Svante L. H. Zipfel, Luke D. Halder, Sibel Mutlutürk, Sonia Wulf, Evaldas Girdauskas, Hermann Reichenspurner, Rolf A. K. Stahl, Berit Jungnickel, Thorsten Wiech, Peter F. Zipfel, Christine Skerka
Nat Commun. 2019; 10: 2961. Published online 2019 Jul 4. doi: 10.1038/s41467-019-10766-0
PMCID:
PMC6609651
AbstractArticlePDF–2.4M
10.
Membrane-association of EMR2/ADGRE2-NTF is regulated by site-specific N-glycosylation
Yi-Shu Huang, Nien-Yi Chiang, Gin-Wen Chang, Hsi-Hsien Lin
Sci Rep. 2018; 8: 4532. Published online 2018 Mar 14. doi: 10.1038/s41598-018-22849-x
PMCID:
PMC5852045
AbstractArticlePDF–1.7M
11.
miR-99a reveals two novel oncogenic proteins E2F2 and EMR2 and represses stemness in lung cancer
Andrea Feliciano, Yoelsis Garcia-Mayea, Luz Jubierre, Cristina Mir, Manuela Hummel, Josep Castellvi, Javier Hernández-Losa, Rosanna Paciucci, Irene Sansano, Yilin Sun, Santiago Ramón y Cajal, Hiroshi Kondon, Aroa Soriano, Miguel Segura, Alex Lyakhovich, Matilde E LLeonart
Cell Death Dis. 2017 Oct; 8(10): e3141. Published online 2017 Oct 26. doi: 10.1038/cddis.2017.544
PMCID:
PMC5680913
AbstractArticlePDF–4.1M
12.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
13.
Increased EMR2 expression on neutrophils correlates with disease severity and predicts overall mortality in cirrhotic patients
Chien-Hao Huang, Wen-Juei Jeng, Yu-Pin Ho, Wei- Teng, Yi-Chung Hsieh, Wei-Ting Chen, Yi-Cheng Chen, Hsi-Hsien Lin, I-Shyan Sheen, Chun-Yen Lin
Sci Rep. 2016; 6: 38250. Published online 2016 Dec 1. doi: 10.1038/srep38250
PMCID:
PMC5131291
AbstractArticlePDF–1.0M
14.
Vibratory Urticaria Associated with a Missense Variant in ADGRE2
Steven E. Boyden, Avanti Desai, Glenn Cruse, Michael L. Young, Hyejeong C. Bolan, Linda M. Scott, A. Robin Eisch, R. Daniel Long, Chyi-Chia R. Lee, Colleen L. Satorius, Andrew J. Pakstis, Ana Olivera, James C. Mullikin, Eliane Chouery, André Mégarbané, Myrna Medlej-Hashim, Kenneth K. Kidd, Daniel L. Kastner, Dean D. Metcalfe, Hirsh D. Komarow
N Engl J Med. Author manuscript; available in PMC 2016 Aug 18.
Published in final edited form as: N Engl J Med. 2016 Feb 18; 374(7): 656–663. Published online 2016 Feb 3. doi: 10.1056/NEJMoa1500611
PMCID:
PMC4782791
AbstractArticlePDF–1.5M
15.
Expression of CD11c and EMR2 on neutrophils: potential diagnostic biomarkers for sepsis and systemic inflammation
S M Lewis, D F Treacher, J Edgeworth, G Mahalingam, C S Brown, T A Mare, M Stacey, R Beale, KA Brown
Clin Exp Immunol. 2015 Nov; 182(2): 184–194. Published online 2015 Sep 22. doi: 10.1111/cei.12679
PMCID:
PMC4608508
AbstractArticlePDF–404K
16.
International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G Protein–Coupled Receptors
Jörg Hamann, Gabriela Aust, Demet Araç, Felix B. Engel, Caroline Formstone, Robert Fredriksson, Randy A. Hall, Breanne L. Harty, Christiane Kirchhoff, Barbara Knapp, Arunkumar Krishnan, Ines Liebscher, Hsi-Hsien Lin, David C. Martinelli, Kelly R. Monk, Miriam C. Peeters, Xianhua Piao, Simone Prömel, Torsten Schöneberg, Thue W. Schwartz, Kathleen Singer, Martin Stacey, Yuri A. Ushkaryov, Mario Vallon, Uwe Wolfrum, Mathew W. Wright, Lei Xu, Tobias Langenhan, Helgi B. Schiöth
Pharmacol Rev. 2015 Apr; 67(2): 338–367. Published online 2015 Apr. doi: 10.1124/pr.114.009647
PMCID:
PMC4394687
AbstractArticlePDF–3.0M
17.
Systematic identification of pathological lamin A interactors
Travis A. Dittmer, Nidhi Sahni, Nard Kubben, David E. Hill, Marc Vidal, Rebecca C. Burgess, Vassilis Roukos, Tom Misteli
Mol Biol Cell. 2014 May 1; 25(9): 1493–1510. doi: 10.1091/mbc.E14-02-0733
PMCID:
PMC4004598
AbstractArticlePDF–3.5M
18.
Activation of Myeloid Cell-Specific Adhesion Class G Protein-Coupled Receptor EMR2 via Ligation-Induced Translocation and Interaction of Receptor Subunits in Lipid Raft Microdomains
Yi-Shu Huang, Nien-Yi Chiang, Ching-Hsun Hu, Cheng-Chih Hsiao, Kai-Fong Cheng, Wen-Pin Tsai, Simon Yona, Martin Stacey, Siamon Gordon, Gin-Wen Chang, Hsi-Hsien Lin
Mol Cell Biol. 2012 Apr; 32(8): 1408–1420. doi: 10.1128/MCB.06557-11
PMCID:
PMC3318590
AbstractArticlePDF–2.6M
19.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
20.
Functional Cross-interaction of the Fragments Produced by the Cleavage of Distinct Adhesion G-protein-coupled Receptors
John-Paul Silva, Vera Lelianova, Colin Hopkins, Kirill E. Volynski, Yuri Ushkaryov
J Biol Chem. 2009 Mar 6; 284(10): 6495–6506. doi: 10.1074/jbc.M806979200
PMCID:
PMC2649109
AbstractArticlePDF–783K

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