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Select item 108111901.

Semaphorin3B promotes an anti-inflammatory and pro-resolving phenotype in macrophages from rheumatoid arthritis patients in a MerTK-dependent manner

Sara Martínez-Ramos, Carlos Rafael-Vidal, Beatriz Malvar-Fernández, Nair Pérez, Coral Mouriño, Sara García Pérez, Francisco J. Maceiras Pan, Carmen Conde, Jose María Pego-Reigosa, Samuel García

Front Immunol. 2023; 14: 1268144. Published online 2024 Jan 12. doi: 10.3389/fimmu.2023.1268144

PMCID:: PMC10811190

Abstract Article PDF–2.1M

Select item 102374222.

TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing

Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan

Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233

PMCID:: PMC10237422

Abstract Article PDF–23M

Select item 93225713.

Central Role of Semaphorin 3B in a Serum‐Induced Arthritis Model and Reduced Levels in Patients With Rheumatoid Arthritis

Ana Igea, Tiago Carvalheiro, Beatriz Malvar‐Fernández, Sara Martinez‐Ramos, Carlos Rafael‐Vidal, Ellis Niemantsverdriet, Jezabel Varadé, Andrea Fernández‐Carrera, Norman Jimenez, Trudy McGarry, Angela Rodriguez‐Trillo, Douglas Veale, Ursula Fearon, Carmen Conde, Jose M. Pego‐Reigosa, África González‐Fernández, Kris A. Reedquist, Timothy R. D. J. Radstake, Annette van der Helm‐Van Mil, Samuel García

Arthritis Rheumatol. 2022 Jun; 74(6): 972–983. Published online 2022 Apr 13. doi: 10.1002/art.42065

PMCID:: PMC9322571

Abstract Article PDF–1.9M

Select item 92316234.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 85664735.

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma

Tatenda Mahlokozera, Bhuvic Patel, Hao Chen, Patrick Desouza, Xuan Qu, Diane D. Mao, Daniel Hafez, Wei Yang, Rukayat Taiwo, Mounica Paturu, Afshin Salehi, Amit D. Gujar, Gavin P. Dunn, Nima Mosammaparast, Allegra A. Petti, Hiroko Yano, Albert H. Kim

Nat Commun. 2021; 12: 6321. Published online 2021 Nov 3. doi: 10.1038/s41467-021-26653-6

PMCID:: PMC8566473

Abstract Article PDF–2.7M

Select item 81650306.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 79688447.

GREB1: An evolutionarily conserved protein with a glycosyltransferase domain links ERα glycosylation and stability to cancer

Eun Myoung Shin, Vinh Thang Huynh, Sultan Abda Neja, Chia Yi Liu, Anandhkumar Raju, Kelly Tan, Nguan Soon Tan, Jayantha Gunaratne, Xuezhi Bi, Lakshminarayan M. Iyer, L. Aravind, Vinay Tergaonkar

Sci Adv. 2021 Mar; 7(12): eabe2470. Published online 2021 Mar 17. doi: 10.1126/sciadv.abe2470

PMCID:: PMC7968844

Abstract Article PDF–1.1M

Select item 71699838.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 71132439.

Interaction between the scaffold proteins CBP by IQGAP1 provides an interface between gene expression and cytoskeletal activity

Simone Kosol, Sara Contreras-Martos, Alessandro Piai, Mihaly Varadi, Tamas Lazar, Angela Bekesi, Pierre Lebrun, Isabella C. Felli, Roberta Pierattelli, Peter Tompa

Sci Rep. 2020; 10: 5753. Published online 2020 Apr 1. doi: 10.1038/s41598-020-62069-w

PMCID:: PMC7113243

Abstract Article PDF–4.2M

Select item 677813710.

The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis

Luisa Capalbo, Zuni I. Bassi, Marco Geymonat, Sofia Todesca, Liviu Copoiu, Anton J. Enright, Giuliano Callaini, Maria Giovanna Riparbelli, Lu Yu, Jyoti S. Choudhary, Enrico Ferrero, Sally Wheatley, Max E. Douglas, Masanori Mishima, Pier Paolo D’Avino

Nat Commun. 2019; 10: 4513. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12507-9

PMCID:: PMC6778137

Abstract Article PDF–7.8M

Select item 659846211.

Expression of Semaphorin 3B (SEMA3B) in Various Grades of Endometrial Cancer

Konrad Dziobek, Marcin Opławski, Beniamin Grabarek, Nikola Zmarzły, Piotr Januszyk, Iwona Adwent, Dariusz Dąbruś, Ewa Leśniak, Robert Kiełbasiński, Przemysław Kieszkowski, Dariusz Boroń

Med Sci Monit. 2019; 25: 4569–4574. Published online 2019 Jun 20. doi: 10.12659/MSM.916762

PMCID:: PMC6598462

Abstract Article PDF–1.8M

Select item 655859712.

Epidermal growth factor‐containing fibulin‐like extracellular matrix protein 1 (EFEMP1) suppressed the growth of hepatocellular carcinoma cells by promoting Semaphorin 3B(SEMA3B)

Jiangfeng Hu, Bensong Duan, Weiliang Jiang, Sengwang Fu, Hengjun Gao, Lungen Lu

Cancer Med. 2019 Jun; 8(6): 3152–3166. Published online 2019 Apr 11. doi: 10.1002/cam4.2144

PMCID:: PMC6558597

Abstract Article PDF–1.8M

Select item 567858113.

RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination

Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski

BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9

PMCID:: PMC5678581

Abstract Article PDF–3.2M

Select item 562910414.

GATA3 Targets Semaphorin 3B in Mammary Epithelial Cells to Suppress Breast Cancer Progression and Metastasis

Payam Shahi, Chih-Yang Wang, Jonathan Chou, Catharina Hagerling, Hugo Gonzalez Velozo, Aline Ruderisch, Ying Yu, Ming-Derg Lai, Zena Werb

Oncogene. Author manuscript; available in PMC 2017 Dec 5.

Published in final edited form as: Oncogene. 2017 Oct 5; 36(40): 5567–5575. Published online 2017 Jun 5. doi: 10.1038/onc.2017.165

PMCID:: PMC5629104

Abstract Article PDF–1.1M

Select item 549522515.

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing

Teng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, Myles Brown

Proc Natl Acad Sci U S A. 2017 Jun 27; 114(26): E5207–E5215. Published online 2017 Jun 13. doi: 10.1073/pnas.1617467114

PMCID:: PMC5495225

Abstract Article PDF–1.3M

Select item 442730016.

Tumor Suppressor Function of the SEMA3B Gene in Human Lung and Renal Cancers

Vitaly I. Loginov, Alexey A. Dmitriev, Vera N. Senchenko, Irina V. Pronina, Dmitry S. Khodyrev, Anna V. Kudryavtseva, George S. Krasnov, Ganna V. Gerashchenko, Larisa I. Chashchina, Tatiana P. Kazubskaya, Tatiana T. Kondratieva, Michael I. Lerman, Debora Angeloni, Eleonora A. Braga, Vladimir I. Kashuba

PLoS One. 2015; 10(5): e0123369. Published online 2015 May 11. doi: 10.1371/journal.pone.0123369

PMCID:: PMC4427300

Abstract Article PDF–2.3M

Select item 422362717.

Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver

Alexandra Naba, Karl R Clauser, Charles A Whittaker, Steven A Carr, Kenneth K Tanabe, Richard O Hynes

BMC Cancer. 2014; 14: 518. Published online 2014 Jul 18. doi: 10.1186/1471-2407-14-518

PMCID:: PMC4223627

Abstract Article PDF–1.5M

Select item 326170818.

Toward an understanding of the protein interaction network of the human liver

Jian Wang, Keke Huo, Lixin Ma, Liujun Tang, Dong Li, Xiaobi Huang, Yanzhi Yuan, Chunhua Li, Wei Wang, Wei Guan, Hui Chen, Chaozhi Jin, Junchen Wei, Wanqiao Zhang, Yongsheng Yang, Qiongming Liu, Ying Zhou, Cuili Zhang, Zhihao Wu, Wangxiang Xu, Ying Zhang, Tao Liu, Donghui Yu, Yaping Zhang, Liang Chen, Dewu Zhu, Xing Zhong, Lixin Kang, Xiang Gan, Xiaolan Yu, Qi Ma, Jing Yan, Li Zhou, Zhongyang Liu, Yunping Zhu, Tao Zhou, Fuchu He, Xiaoming Yang

Mol Syst Biol. 2011; 7: 536. Published online 2011 Oct 11. doi: 10.1038/msb.2011.67

Correction in:: Mol Syst Biol. 2017 Dec; 13(12): 965.

PMCID:: PMC3261708

Abstract Article PDF–2.0M

Select item 317805919.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 282059020.

Hormonal Regulation and Distinct Functions of Semaphorin-3B and Semaphorin-3F in Ovarian Cancer

Doina Joseph, Shuk-Mei Ho, Viqar Syed

Mol Cancer Ther. Author manuscript; available in PMC 2011 Feb 2.

Published in final edited form as: Mol Cancer Ther. 2010 Feb; 9(2): 499. Published online 2010 Feb 2. doi: 10.1158/1535-7163.MCT-09-0664

PMCID:: PMC2820590

Abstract Article PDF–1.3M

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