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Select item 115201011.

SARS-CoV-2 hijacks host CD55, CD59 and factor H to impair antibody-dependent complement-mediated lysis

Laura Gebetsberger, Zahra Malekshahi, Aron Teutsch, Gabor Tajti, Frédéric Fontaine, Nara Marella, André Mueller, Lena Prantl, Hannes Stockinger, Heribert Stoiber, Anna Ohradanova-Repic

Emerg Microbes Infect. 2024; 13(1): 2417868. Published online 2024 Oct 22. doi: 10.1080/22221751.2024.2417868

PMCID:: PMC11520101

Abstract Article PDF–1.3M

Select item 111637272.

Cell surface CD55 traffics to the nucleus leading to cisplatin resistance and stemness by inducing PRC2 and H3K27 trimethylation on chromatin in ovarian cancer

Rashmi Bharti, Goutam Dey, Debjit Khan, Alex Myers, Olivia G. Huffman, Caner Saygin, Chad Braley, Elliott Richards, Naseer Sangwan, Belinda Willard, Justin D. Lathia, Paul L. Fox, Feng Lin, Babal Kant Jha, J. Mark Brown, Jennifer S. Yu, Mohammed Dwidar, Amy Joehlin-Price, Roberto Vargas, Chad M. Michener, Michelle S. Longworth, Ofer Reizes

Mol Cancer. 2024; 23: 121. Published online 2024 Jun 10. doi: 10.1186/s12943-024-02028-5

PMCID:: PMC11163727

Abstract Article PDF–15M

Select item 111588933.

Blockade of bulky lymphoma‐associated CD55 expression by RNA interference overcomes resistance to complement‐dependent cytotoxicity with rituximab

Yasuhito Terui, Takuma Sakurai, Yuko Mishima, Yuji Mishima, Natsuhiko Sugimura, Chino Sasaoka, Kiyotsugu Kojima, Masahiro Yokoyama, Nobuyuki Mizunuma, Shunji Takahashi, Yoshinori Ito, Kiyohiko Hatake

Cancer Sci. 2006 Jan; 97(1): 72–79. Published online 2005 Dec 21. doi: 10.1111/j.1349-7006.2006.00139.x

PMCID:: PMC11158893

Abstract Article PDF–287K

Select item 110343274.

Enhanced expression of the complement regulatory protein CD55 predicts a poor prognosis in colorectal cancer patients

L. G. Durrant, M. A. Chapman, D. J. Buckley, I. Spendlove, R. A. Robins, N. C. Armitage

Cancer Immunol Immunother. 2003 Oct; 52(10): 638–642. Published online 2003 Jun 14. doi: 10.1007/s00262-003-0402-y

PMCID:: PMC11034327

Abstract Article PDF–195K

Select item 110198355.

CD55 in cancer: Complementing functions in a non-canonical manner

Rashmi Bharti, Goutam Dey, Feng Lin, Justin Lathia, Ofer Reizes

Cancer Lett. Author manuscript; available in PMC 2024 Apr 16.

Published in final edited form as: Cancer Lett. 2022 Dec 28; 551: 215935. Published online 2022 Oct 7. doi: 10.1016/j.canlet.2022.215935

PMCID:: PMC11019835

Abstract Article PDF–694K

Select item 106176736.

The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation

Xin Gu, Christopher Nardone, Nolan Kamitaki, Aoyue Mao, Stephen J. Elledge, Michael E. Greenberg

Science. Author manuscript; available in PMC 2023 Oct 31.

Published in final edited form as: Science. 2023 Aug 25; 381(6660): eadh5021. Published online 2023 Aug 25. doi: 10.1126/science.adh5021

PMCID:: PMC10617673

Abstract Article PDF–3.6M

Select item 102809407.

CircNFATC3 promotes the proliferation of gastric cancer through binding to IGF2BP3 and restricting its ubiquitination to enhance CCND1 mRNA stability

Feifei Yang, Qiang Ma, Bo Huang, Xiaolin Wang, Xiaojuan Pan, Ting Yu, Lingyu Ran, Shan Jiang, Haiping Li, Ye Chen, Yuying Liu, Ce Liang, Junwu Ren, Yuying Zhang, Shimin Wang, Wei Li, Bin Xiao

J Transl Med. 2023; 21: 402. Published online 2023 Jun 20. doi: 10.1186/s12967-023-04235-y

PMCID:: PMC10280940

Abstract Article PDF–11M

Select item 102431548.

Ring finger protein 12 activates AKT signalling to promote the progression of liver cancer by interacting with EGFR

Chengpeng Yu, Dean Rao, Tiantian Wang, Jiaqi Sheng, Enjun Lv, Long Zhang, Xun Lu, Jingjing Yu, Huifang Liang, Jia Song, Wenjie Huang

J Cell Mol Med. 2023 Jun; 27(11): 1523–1538. Published online 2023 May 2. doi: 10.1111/jcmm.17757

PMCID:: PMC10243154

Abstract Article PDF–51M

Select item 99934569.

miR-132-3p regulates antibody-mediated complement-dependent cytotoxicity in colon cancer cells by directly targeting CD55

Yu Fan, Juan Liao, Yu Wang, Zhu Wang, Hong Zheng, Yanping Wang

Clin Exp Immunol. 2023 Jan; 211(1): 57–67. Published online 2022 Dec 26. doi: 10.1093/cei/uxac120

PMCID:: PMC9993456

Abstract Article PDF–2.1M

Select item 988992710.

The genetic and epigenetic regulation of CD55 and its pathway analysis in colon cancer

Jiawei Liu, Ning Fu, Zhenbang Yang, Ang Li, Hongjiao Wu, Ye Jin, Qinqin Song, Shanshan Ji, Hongxue Xu, Zhi Zhang, Xuemei Zhang

Front Immunol. 2022; 13: 947136. Published online 2023 Jan 18. doi: 10.3389/fimmu.2022.947136

PMCID:: PMC9889927

Abstract Article PDF–3.8M

Select item 979798811.

TBK1 posphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1

Jianwen Zhou, Nikoline Lander Rasmussen, Hallvard Lauritz Olsvik, Vyacheslav Akimov, Zehan Hu, Gry Evjen, Stéphanie Kaeser-Pebernard, Devanarayanan Siva Sankar, Carole Roubaty, Pauline Verlhac, Nicole van de Beek, Fulvio Reggiori, Yakubu Princely Abudu, Blagoy Blagoev, Trond Lamark, Terje Johansen, Jörn Dengjel

J Cell Biol. 2023 Feb 6; 222(2): e202108144. Published online 2022 Dec 27. doi: 10.1083/jcb.202108144

PMCID:: PMC9797988

Abstract Article PDF–6.9M

Select item 954399012.

The active form of Helicobacter pylori vacuolating cytotoxin induces decay‐accelerating factor CD55 in association with intestinal metaplasia in the human gastric mucosa

Kazuyo Kaneko, Abed M Zaitoun, Darren P Letley, Joanne L Rhead, Javier Torres, Ian Spendlove, John C Atherton, Karen Robinson

J Pathol. 2022 Oct; 258(2): 199–209. Published online 2022 Aug 18. doi: 10.1002/path.5990

PMCID:: PMC9543990

Abstract Article PDF–15M

Select item 923162313.

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1

Boris Simonetti, James L. Daly, Lorena Simón-Gracia, Katja Klein, Saroja Weeratunga, Carlos Antón-Plágaro, Allan Tobi, Lorna Hodgson, Philip A. Lewis, Kate J. Heesom, Deborah K. Shoemark, Andrew D. Davidson, Brett M. Collins, Tambet Teesalu, Yohei Yamauchi, Peter J. Cullen

Proc Natl Acad Sci U S A. 2022 Jun 21; 119(25): e2201980119. Published online 2022 Jun 13. doi: 10.1073/pnas.2201980119

PMCID:: PMC9231623

Abstract Article PDF–6.0M

Select item 917548214.

LukS-PV inhibits hepatocellular carcinoma cells migration by downregulating HDAC6 expression

Xuexue Xu, Pengsheng Ding, Lan Shi, Gang Wu, Xiaoling Ma

BMC Cancer. 2022; 22: 630. Published online 2022 Jun 8. doi: 10.1186/s12885-022-09680-4

PMCID:: PMC9175482

Abstract Article PDF–15M

Select item 905883615.

The involvement of Parkin-dependent mitophagy in the anti-cancer activity of Ginsenoside

Xin Sun, Yeting Hong, Yuhan Shu, Caixia Wu, Guiqin Ye, Hanxiao Chen, Hongying Zhou, Ruilan Gao, Jianbin Zhang

J Ginseng Res. 2022 Mar; 46(2): 266–274. Published online 2021 Jul 8. doi: 10.1016/j.jgr.2021.06.009

PMCID:: PMC9058836

Abstract Article PDF–2.9M

Select item 874895816.

EZH2 depletion potentiates MYC degradation inhibiting neuroblastoma and small cell carcinoma tumor formation

Liyuan Wang, Chan Chen, Zemin Song, Honghong Wang, Minghui Ye, Donghai Wang, Wenqian Kang, Hudan Liu, Guoliang Qing

Nat Commun. 2022; 13: 12. Published online 2022 Jan 10. doi: 10.1038/s41467-021-27609-6

PMCID:: PMC8748958

Abstract Article PDF–3.0M

Select item 824873017.

Complement Decay-Accelerating Factor is a modulator of influenza A virus lung immunopathology

Nuno Brito Santos, Zoé Enderlin Vaz da Silva, Catarina Gomes, Celso A. Reis, Maria João Amorim

PLoS Pathog. 2021 Jul; 17(7): e1009381. Published online 2021 Jul 1. doi: 10.1371/journal.ppat.1009381

PMCID:: PMC8248730

Abstract Article PDF–5.1M

Select item 819131618.

Structural basis for CD97 recognition of the decay-accelerating factor CD55 suggests mechanosensitive activation of adhesion GPCRs

Minghui Niu, Shengzhao Xu, Jie Yang, Deqiang Yao, Na Li, Jie Yan, Guisheng Zhong, Gaojie Song

J Biol Chem. 2021 Jan-Jun; 296: 100776. Published online 2021 May 14. doi: 10.1016/j.jbc.2021.100776

PMCID:: PMC8191316

Abstract Article PDF–3.2M

Select item 818421419.

Erythrocyte CD55 mediates the internalization of Plasmodium falciparum parasites

Bikash Shakya, Saurabh D Patel, Yoshihiko Tani, Elizabeth S Egan

eLife. 2021; 10: e61516. Published online 2021 May 24. doi: 10.7554/eLife.61516

PMCID:: PMC8184214

Abstract Article PDF–2.3M

Select item 816503020.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

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