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Items: 1 to 20 of 30

1.
The pro-survival Bcl-2 family member A1 delays spontaneous and FAS ligand-induced apoptosis of activated neutrophils
Robyn L. Schenk, Lahiru Gangoda, Kate E. Lawlor, Lorraine A. O’Reilly, Andreas Strasser, Marco J. Herold
Cell Death Dis. 2020 Jun; 11(6): 474. Published online 2020 Jun 18. doi: 10.1038/s41419-020-2676-9
PMCID:
PMC7303176
ArticlePDF–571K
2.
Anti-apoptotic A1 is not essential for lymphoma development in Eµ-Myc mice but helps sustain transplanted Eµ-Myc tumour cells
Mark Mensink, Natasha S. Anstee, Mikara Robati, Robyn L. Schenk, Marco J. Herold, Suzanne Cory, Cassandra J. Vandenberg
Cell Death Differ. 2018 Apr; 25(4): 795–806. Published online 2018 Jan 16. doi: 10.1038/s41418-017-0045-8
PMCID:
PMC5864240
AbstractArticlePDF–982K
3.
Epstein-Barr virus ensures B cell survival by uniquely modulating apoptosis at early and late times after infection
Alexander M Price, Joanne Dai, Quentin Bazot, Luv Patel, Pavel A Nikitin, Reza Djavadian, Peter S Winter, Cristina A Salinas, Ashley Perkins Barry, Kris C Wood, Eric C Johannsen, Anthony Letai, Martin J Allday, Micah A Luftig
eLife. 2017; 6: e22509. Published online 2017 Apr 20. doi: 10.7554/eLife.22509
PMCID:
PMC5425254
AbstractArticlePDF–3.0M
4.
Anti-apoptotic proteins BCL-2, MCL-1 and A1 summate collectively to maintain survival of immune cell populations both in vitro and in vivo
Emma M Carrington, Yifan Zhan, Jamie L Brady, Jian-Guo Zhang, Robyn M Sutherland, Natasha S Anstee, Robyn L Schenk, Ingela B Vikstrom, Rebecca B Delconte, David Segal, Nicholas D Huntington, Philippe Bouillet, David M Tarlinton, David CS Huang, Andreas Strasser, Suzanne Cory, Marco J Herold, Andrew M Lew
Cell Death Differ. 2017 May; 24(5): 878–888. Published online 2017 Mar 31. doi: 10.1038/cdd.2017.30
PMCID:
PMC5423112
AbstractArticlePDF–862K
5.
MYC selects against reduced BCL2A1/A1 protein expression during B cell lymphomagenesis
M Sochalska, F Schuler, J G Weiss, M Prchal-Murphy, V Sexl, A Villunger
Oncogene. 2017 Apr; 36(15): 2066–2073. Published online 2016 Oct 3. doi: 10.1038/onc.2016.362
PMCID:
PMC5395700
AbstractArticlePDF–2.1M
6.
Constitutive expression of the anti‐apoptotic Bcl‐2 family member A1 in murine endothelial cells leads to transplant tolerance
L. A. Smyth, L. Meader, F. Xiao, M. Woodward, H. J. M. Brady, R. Lechler, G. Lombardi
Clin Exp Immunol. 2017 May; 188(2): 219–225. Published online 2017 Mar 2. doi: 10.1111/cei.12931
PMCID:
PMC5383447
AbstractArticlePDF–302K
7.
Characterisation of mice lacking all functional isoforms of the pro-survival BCL-2 family member A1 reveals minor defects in the haematopoietic compartment
Robyn L Schenk, Selma Tuzlak, Emma M Carrington, Yifan Zhan, Susanne Heinzel, Charis E Teh, Daniel H Gray, Lin Tai, Andrew M Lew, Andreas Villunger, Andreas Strasser, Marco J Herold
Cell Death Differ. 2017 Mar; 24(3): 534–545. Published online 2017 Jan 13. doi: 10.1038/cdd.2016.156
PMCID:
PMC5344213
AbstractArticlePDF–3.8M
8.
The BCL-2 pro-survival protein A1 is dispensable for T cell homeostasis on viral infection
Selma Tuzlak, Robyn L Schenk, Ajithkumar Vasanthakumar, Simon P Preston, Manuel D Haschka, Dimitra Zotos, Axel Kallies, Andreas Strasser, Andreas Villunger, Marco J Herold
Cell Death Differ. 2017 Mar; 24(3): 523–533. Published online 2017 Jan 13. doi: 10.1038/cdd.2016.155
PMCID:
PMC5344212
AbstractArticlePDF–1.7M
9.
Conditional knockdown of BCL2A1 reveals rate-limiting roles in BCR-dependent B-cell survival
M Sochalska, E Ottina, S Tuzlak, S Herzog, M Herold, A Villunger
Cell Death Differ. 2016 Apr; 23(4): 628–639. Published online 2015 Oct 9. doi: 10.1038/cdd.2015.130
PMCID:
PMC4986635
AbstractArticlePDF–4.1M
10.
Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA
Xiaoyun Liu, Yan Jiao, Yanhong Cao, Nan Deng, Yonghui Ma, Karen A. Hasty, Andrew Kang, Hong Chen, John M. Stuart, Weikuan Gu
BMC Immunol. 2016; 17: 25. Published online 2016 Aug 2. doi: 10.1186/s12865-016-0163-y
PMCID:
PMC4970213
AbstractArticlePDF–2.5M
11.
Selective Impairment of TH17-Differentiation and Protection against Autoimmune Arthritis after Overexpression of BCL2A1 in T Lymphocytes
Marcos Iglesias, Juan Jesús Augustin, Pilar Alvarez, Inés Santiuste, Jorge Postigo, Jesús Merino, Ramón Merino
PLoS One. 2016; 11(7): e0159714. Published online 2016 Jul 19. doi: 10.1371/journal.pone.0159714
PMCID:
PMC4951111
AbstractArticlePDF–2.7M
12.
Lessons from gain- and loss-of-function models of pro-survival Bcl2 family proteins: implications for targeted therapy
Maja Sochalska, Selma Tuzlak, Alexander Egle, Andreas Villunger
FEBS J. Author manuscript; available in PMC 2015 Sep 8.
Published in final edited form as: FEBS J. 2015 Mar; 282(5): 834–849. Published online 2015 Jan 23. doi: 10.1111/febs.13188
PMCID:
PMC4562365
AbstractArticlePDF–899K
13.
Knockdown of the Antiapoptotic Bcl-2 Family Member A1/Bfl-1 Protects Mice from Anaphylaxis
Eleonora Ottina, Katarina Lyberg, Maja Sochalska, Andreas Villunger, Gunnar P. Nilsson
J Immunol. 2015 Feb 1; 194(3): 1316–1322. Published online 2014 Dec 29. doi: 10.4049/jimmunol.1400637
PMCID:
PMC4298126
AbstractArticlePDF–972K
14.
BCL2A1a Over-Expression in Murine Hematopoietic Stem and Progenitor Cells Decreases Apoptosis and Results in Hematopoietic Transformation
Jean-Yves Métais, Thomas Winkler, Julia T. Geyer, Rodrigo T. Calado, Peter D. Aplan, Michael A. Eckhaus, Cynthia E. Dunbar
PLoS One. 2012; 7(10): e48267. Published online 2012 Oct 30. doi: 10.1371/journal.pone.0048267
PMCID:
PMC3484072
AbstractArticlePDF–894K
15.
Targeting antiapoptotic A1/Bfl-1 by in vivo RNAi reveals multiple roles in leukocyte development in mice
Eleonora Ottina, Francesca Grespi, Denise Tischner, Claudia Soratroi, Stephan Geley, Andreas Ploner, Holger M. Reichardt, Andreas Villunger, Marco J. Herold
Blood. 2012 Jun 21; 119(25): 6032–6042. Prepublished online 2012 May 11. doi: 10.1182/blood-2011-12-399089
PMCID:
PMC3418769
AbstractArticle
16.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
17.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
18.
Defective ubiquitin-mediated degradation of antiapoptotic Bfl-1 predisposes to lymphoma
Gaofeng Fan, Matthew J. Simmons, Sheng Ge, Jui Dutta-Simmons, Jérôme Kucharczak, Yacov Ron, David Weissmann, Chiann-Chyi Chen, Chandreyee Mukherjee, Eileen White, Céline Gélinas
Blood. 2010 Apr 29; 115(17): 3559–3569. Prepublished online 2010 Feb 25. doi: 10.1182/blood-2009-08-236760
PMCID:
PMC2867266
AbstractArticle
19.
NFAT but not NF-κB is critical for transcriptional induction of the prosurvival gene A1 after IgE receptor activation in mast cells
Erik Ullerås, Mats Karlberg, Christine Möller Westerberg, Jessica Alfredsson, Steve Gerondakis, Andreas Strasser, Gunnar Nilsson
Blood. 2008 Mar 15; 111(6): 3081–3089. Prepublished online 2008 Jan 8. doi: 10.1182/blood-2006-10-053371
PMCID:
PMC2265451
AbstractArticle
20.
The BCL2A1 gene as a pre–T cell receptor–induced regulator of thymocyte survival
Malay Mandal, Christine Borowski, Teresa Palomero, Adolfo A. Ferrando, Philipp Oberdoerffer, Fanyong Meng, Antonio Ruiz-Vela, Maria Ciofani, Juan-Carlos Zuniga-Pflucker, Isabella Screpanti, A. Thomas Look, Stanley J. Korsmeyer, Klaus Rajewsky, Harald von Boehmer, Iannis Aifantis
J Exp Med. 2005 Feb 21; 201(4): 603–614. doi: 10.1084/jem.20041924
PMCID:
PMC2213063
AbstractArticlePDF–2.5M

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