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Select item 110146571.

A BMP-controlled metabolic/epigenetic signaling cascade directs midfacial morphogenesis

Jingwen Yang, Lingxin Zhu, Haichun Pan, Hiroki Ueharu, Masako Toda, Qian Yang, Shawn A. Hallett, Lorin E. Olson, Yuji Mishina

J Clin Invest. 2024 Apr 15; 134(8): e165787. Published online 2024 Mar 11. doi: 10.1172/JCI165787

PMCID:: PMC11014657

Abstract Article PDF–16M

Select item 109635802.

Multiscale mechanical characterisation of the craniofacial system under external forces

Marius Didziokas, Dominic Jones, Ali Alazmani, Miranda Steacy, Erwin Pauws, Mehran Moazen

Biomech Model Mechanobiol. 2024; 23(2): 675–685. Published online 2024 Jan 13. doi: 10.1007/s10237-023-01799-y

PMCID:: PMC10963580

Abstract Article PDF–3.6M

Select item 109057463.

BRD4 binds to active cranial neural crest enhancers to regulate RUNX2 activity during osteoblast differentiation

Rachel E. Musa, Kaitlyn L. Lester, Gabrielle Quickstad, Sara Vardabasso, Trevor V. Shumate, Ryan T. Salcido, Kai Ge, Karl B. Shpargel

Development. 2024 Jan 15; 151(2): dev202110. Published online 2024 Jan 24. doi: 10.1242/dev.202110

PMCID:: PMC10905746

Abstract Article

Select item 105916724.

Distinct mechanisms for sebaceous gland self-renewal and regeneration provide durability in response to injury

Natalia A. Veniaminova, Yunlong Y. Jia, Adrien M. Hartigan, Thomas J. Huyge, Shih-Ying Tsai, Marina Grachtchouk, Seitaro Nakagawa, Andrzej A. Dlugosz, Scott X. Atwood, Sunny Y. Wong

Cell Rep. Author manuscript; available in PMC 2023 Oct 23.

Published in final edited form as: Cell Rep. 2023 Sep 26; 42(9): 113121. Published online 2023 Sep 19. doi: 10.1016/j.celrep.2023.113121

PMCID:: PMC10591672

Abstract Article PDF–3.4M

Select item 105772785.

Rhox8 homeobox gene ablation leads to rete testis abnormality and male subfertility in mice

Yeongseok Oh, Maho Kasu, Constence J Bottoms, Jenna C Douglas, Nikola Sekulovski, Kanako Hayashi, James A MacLean II

Biol Reprod. 2023 Oct; 109(4): 520–532. Published online 2023 Jul 20. doi: 10.1093/biolre/ioad077

PMCID:: PMC10577278

Abstract Article PDF–1.9M

Select item 105768116.

FGFR2 is essential for salivary gland duct homeostasis and MAPK-dependent seromucous acinar cell differentiation

Marit H. Aure, Jennifer M. Symonds, Carlos U. Villapudua, Joshua T. Dodge, Sabine Werner, Wendy M. Knosp, Matthew P. Hoffman

Nat Commun. 2023; 14: 6485. Published online 2023 Oct 14. doi: 10.1038/s41467-023-42243-0

PMCID:: PMC10576811

Abstract Article PDF–17M

Select item 105456827.

FGF10 mitigates doxorubicin-induced myocardial toxicity in mice via activation of FGFR2b/PHLDA1/AKT axis

De-pu Zhou, Lian-cheng Deng, Xiao Feng, Hui-jing Xu, Ye Tian, Wei-wei Yang, Ping-ping Zeng, Li-hui Zou, Xi-hua Yan, Xia-yan Zhu, Dan-hua Shu, Qiang Guo, Xiao-ying Huang, Saverio Bellusci, Zhenkun Lou, Xiao-kun Li, Jin-San Zhang

Acta Pharmacol Sin. 2023 Oct; 44(10): 2004–2018. Published online 2023 May 24. doi: 10.1038/s41401-023-01101-x

PMCID:: PMC10545682

Abstract Article PDF–7.0M

Select item 105412408.

Role of Fibroblast Growth Factor Receptor 2 (FGFR2) in Corneal Stromal Thinning

Roy Joseph, Akosua Boateng, Om P. Srivastava, Roswell R. Pfister

Invest Ophthalmol Vis Sci. 2023 Sep; 64(12): 40. Published online 2023 Sep 26. doi: 10.1167/iovs.64.12.40

PMCID:: PMC10541240

Abstract Article PDF–3.2M

Select item 104036409.

Feto-maternal cholesterol transport regulated by β-Klotho–FGF15 axis is essential for fetal growth

Kanako Kobayashi, Kazuko Iwasa, Rika Azuma-Suzuki, Takeshi Kawauchi, Yo-ichi Nabeshima

Life Sci Alliance. 2023 Oct; 6(10): e202301916. Published online 2023 Aug 4. doi: 10.26508/lsa.202301916

PMCID:: PMC10403640

Abstract Article PDF–2.1M

Select item 1039920310.

FRS2-independent GRB2 interaction with FGFR2 is not required for embryonic development

James F. Clark, Philippe Soriano

Biol Open. 2023 Jul 15; 12(7): bio059942. Published online 2023 Jul 27. doi: 10.1242/bio.059942

PMCID:: PMC10399203

Abstract Article PDF–6.3M

Select item 1035896711.

Influence of FGF4 and BMP4 on FGFR2 dynamics during the segregation of epiblast and primitive endoderm cells in the pre-implantation mouse embryo

Marcelo D. Goissis, Brian Bradshaw, Eszter Posfai, Janet Rossant

PLoS One. 2023; 18(7): e0279515. Published online 2023 Jul 20. doi: 10.1371/journal.pone.0279515

PMCID:: PMC10358967

Abstract Article PDF–1.5M

Select item 1031728312.

Spontaneous acinar and ductal regrowth after meibomian gland atrophy induced by deletion of FGFR2 in a mouse model

Xiaowei Yang, Xingwu Zhong, Andrew JW. Huang, Lixing W. Reneker

Ocul Surf. Author manuscript; available in PMC 2023 Jul 3.

Published in final edited form as: Ocul Surf. 2022 Oct; 26: 300–309. Published online 2021 Nov 16. doi: 10.1016/j.jtos.2021.11.005

PMCID:: PMC10317283

Abstract Article PDF–3.5M

Select item 1026824013.

ZBTB20 is essential for cochlear maturation and hearing in mice

Zhifang Xie, Xian-Hua Ma, Qiu-Fang Bai, Jie Tang, Jian-He Sun, Fei Jiang, Wei Guo, Chen-Ma Wang, Rui Yang, Yin-Chuan Wen, Fang-Yuan Wang, Yu-Xia Chen, Hai Zhang, David Z. He, Matthew W. Kelley, Shiming Yang, Weiping J. Zhang

Proc Natl Acad Sci U S A. 2023 Jun 13; 120(24): e2220867120. Published online 2023 Jun 6. doi: 10.1073/pnas.2220867120

PMCID:: PMC10268240

Abstract Article PDF–7.7M

Select item 1023444314.

Niche-mediated repair of airways is directed in an occupant-dependent manner

Handeng Lyu, Rachel Warren, Shan Gao, Kylie Klinkhammer, Tingting Yuan, Jin-San Zhang, Douglas Brownfield, Xiaokun Li, Stijn P. De Langhe

Cell Rep. Author manuscript; available in PMC 2023 Jun 1.

Published in final edited form as: Cell Rep. 2022 Dec 20; 41(12): 111863. doi: 10.1016/j.celrep.2022.111863

PMCID:: PMC10234443

Abstract Article PDF–3.2M

Select item 1012146815.

Loss of Fgf9 in mice leads to pancreatic hypoplasia and asplenia

Sophie Patzek, Zhe Liu, Sean de la O, Sean Chang, Lauren E. Byrnes, Xiuqin Zhang, David M. Ornitz, Julie B. Sneddon

iScience. 2023 Apr 21; 26(4): 106500. Published online 2023 Mar 25. doi: 10.1016/j.isci.2023.106500

PMCID:: PMC10121468

Abstract Article PDF–12M

Select item 1011291816.

FGF signaling regulates salivary gland branching morphogenesis by modulating cell adhesion

Ayan T. Ray, Philippe Soriano

Development. 2023 Mar 15; 150(6): dev201293. Published online 2023 Mar 20. doi: 10.1242/dev.201293

PMCID:: PMC10112918

Abstract Article

Select item 1011042317.

Sp3 is essential for normal lung morphogenesis and cell cycle progression during mouse embryonic development

Alyssa M. McCoy, Omar Lakhdari, Sayane Shome, Kaitlin Caoili, Gilberto E. Hernandez, Nima Aghaeepour, Lindsay D. Butcher, Kathleen Fisch, Lawrence S. Prince

Development. 2023 Mar 1; 150(5): dev200839. Published online 2023 Mar 3. doi: 10.1242/dev.200839

PMCID:: PMC10110423

Abstract Article

Select item 1007983818.

OTUB1 promotes osteoblastic bone formation through stabilizing FGFR2

Qiong Zhu, Yesheng Fu, Chun-Ping Cui, Yi Ding, Zhikang Deng, Chao Ning, Fan Hu, Chen Qiu, Biyue Yu, Xuemei Zhou, Guan Yang, Jiang Peng, Weiguo Zou, Cui Hua Liu, Lingqiang Zhang

Signal Transduct Target Ther. 2023; 8: 142. Published online 2023 Apr 7. doi: 10.1038/s41392-023-01354-2

PMCID:: PMC10079838

Abstract Article PDF–5.3M

Select item 1001765719.

Mesenchyme-derived vertebrate lonesome kinase controls lung organogenesis by altering the matrisome

Salome M. Brütsch, Elizabeta Madzharova, Sophia Pantasis, Till Wüstemann, Selina Gurri, Heiko Steenbock, Amiq Gazdhar, Gisela Kuhn, Peter Angel, Saverio Bellusci, Jürgen Brinckmann, Ulrich auf dem Keller, Sabine Werner, Mattia R. Bordoli

Cell Mol Life Sci. 2023 Apr; 80(4): 89. Published online 2023 Mar 15. doi: 10.1007/s00018-023-04735-6