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Select item 94897161.

Hnrnpk maintains chondrocytes survival and function during growth plate development via regulating Hif1α-glycolysis axis

Yuyu Chen, Jinna Wu, Shun Zhang, Wenjie Gao, Zhiheng Liao, Taifeng Zhou, Yongyong Li, Deying Su, Hengyu Liu, Xiaoming Yang, Peiqiang Su, Caixia Xu

Cell Death Dis. 2022 Sep; 13(9): 803. Published online 2022 Sep 20. doi: 10.1038/s41419-022-05239-0

PMCID:: PMC9489716

Abstract Article PDF–8.5M

Select item 90367152.

Duchenne muscular dystrophy trajectory in R-DMDdel52 preclinical rat model identifies COMP as biomarker of fibrosis

Valentina Taglietti, Kaouthar Kefi, Iwona Bronisz-Budzyńska, Busra Mirciloglu, Mathilde Rodrigues, Nastasia Cardone, Fanny Coulpier, Baptiste Periou, Christel Gentil, Melissa Goddard, François-Jérôme Authier, France Pietri-Rouxel, Edoardo Malfatti, Peggy Lafuste, Laurent Tiret, Frederic Relaix

Acta Neuropathol Commun. 2022; 10: 60. Published online 2022 Apr 25. doi: 10.1186/s40478-022-01355-2

PMCID:: PMC9036715

Abstract Article PDF–17M

Select item 88288743.

The collagen receptor, discoidin domain receptor 2, functions in Gli1-positive skeletal progenitors and chondrocytes to control bone development

Fatma F. Mohamed, Chunxi Ge, Randy T. Cowling, Daniel Lucas, Shawn A. Hallett, Noriaki Ono, Abdul-Aziz Binrayes, Barry Greenberg, Renny T. Franceschi

Bone Res. 2022; 10: 11. Published online 2022 Feb 9. doi: 10.1038/s41413-021-00182-w

PMCID:: PMC8828874

Abstract Article PDF–6.8M

Select item 79387704.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 78936425.

TBX1 is required for normal stria vascularis and semicircular canal development

Cong Tian, Kenneth R. Johnson

Dev Biol. Author manuscript; available in PMC 2021 Feb 19.

Published in final edited form as: Dev Biol. 2020 Jan 1; 457(1): 91–103. Published online 2019 Sep 21. doi: 10.1016/j.ydbio.2019.09.013

PMCID:: PMC7893642

Abstract Article PDF–3.5M

Select item 73989036.

Author Correction: Mutations in COMP cause familial carpal tunnel syndrome

Chunyu Li, Ni Wang, Alejandro A. Schäffer, Xilin Liu, Zhuo Zhao, Gene Elliott, Lisa Garrett, Nga Ting Choi, Yueshu Wang, Yufa Wang, Cheng Wang, Jin Wang, Danny Chan, Peiqiang Su, Shusen Cui, Yingzi Yang, Bo Gao

Nat Commun. 2020; 11: 3931. Published online 2020 Aug 3. doi: 10.1038/s41467-020-17845-7

Corrects:: Nat Commun. 2020; 11: 3642.

PMCID:: PMC7398903

Correction PDF–333K

Select item 73717367.

Mutations in COMP cause familial carpal tunnel syndrome

Nat Commun. 2020; 11: 3642. Published online 2020 Jul 20. doi: 10.1038/s41467-020-17378-z

Correction in:: Nat Commun. 2020; 11: 3931.

PMCID:: PMC7371736

Abstract Article PDF–5.9M

Select item 73367298.

Mutant COMP shapes growth and development of skull and facial structures in mice and humans

Alexander Burger, Jasmien Roosenboom, Mohammad Hossain, Seth M. Weinberg, Jacqueline T. Hecht, Karen L. Posey

Mol Genet Genomic Med. 2020 Jul; 8(7): e1251. Published online 2020 Apr 28. doi: 10.1002/mgg3.1251

PMCID:: PMC7336729

Abstract Article PDF–1.1M

Select item 71011399.

Arp2/3 inactivation causes intervertebral disc and cartilage degeneration with dysregulated TonEBP-mediated osmoadaptation

Steven Tessier, Alexandra C. Doolittle, Kimheak Sao, Jeremy D. Rotty, James E. Bear, Veronica Ulici, Richard F. Loeser, Irving M. Shapiro, Brian O. Diekman, Makarand V. Risbud

JCI Insight. 2020 Feb 27; 5(4): e131382. Published online 2020 Feb 27. doi: 10.1172/jci.insight.131382

PMCID:: PMC7101139

Abstract Article PDF–27M

Select item 687990710.

Potential role of cartilage oligomeric matrix protein in the modulation of pulmonary arterial smooth muscle superoxide by hypoxia

Hang Yu, Norah Alruwaili, Bing Hu, Melissa R Kelly, Bin Zhang, Dong Sun, Michael S. Wolin

Am J Physiol Lung Cell Mol Physiol. 2019 Nov 1; 317(5): L569–L577. Published online 2019 Aug 7. doi: 10.1152/ajplung.00080.2018

PMCID:: PMC6879907

Abstract Article

Select item 642362311.

Upregulation of ADAMTS-7 and downregulation of COMP are associated with spontaneous abortion

Yang Mu, Dan-Ni Zhou, Na-Na Yan, Jin-Li Ding, Jing Yang

Mol Med Rep. 2019 Apr; 19(4): 2620–2626. Published online 2019 Jan 28. doi: 10.3892/mmr.2019.9898

PMCID:: PMC6423623

Abstract Article PDF–1.0M

Select item 641271312.

Novel mTORC1 Mechanism Suggests Therapeutic Targets for COMPopathies

Karen L. Posey, Francoise Coustry, Alka C. Veerisetty, Mohammad G. Hossain, Michael J. Gambello, Jacqueline T. Hecht

Am J Pathol. 2019 Jan; 189(1): 132–146. doi: 10.1016/j.ajpath.2018.09.008

PMCID:: PMC6412713

Abstract Article

Select item 632514313.

Thrombospondin-3 augments injury-induced cardiomyopathy by intracellular integrin inhibition and sarcolemmal instability

Tobias G. Schips, Davy Vanhoutte, Alexander Vo, Robert N. Correll, Matthew J. Brody, Hadi Khalil, Jason Karch, Andoria Tjondrokoesoemo, Michelle A. Sargent, Marjorie Maillet, Robert S. Ross, Jeffery D. Molkentin

Nat Commun. 2019; 10: 76. Published online 2019 Jan 8. doi: 10.1038/s41467-018-08026-8

PMCID:: PMC6325143

Abstract Article PDF–5.3M

Select item 612684914.

Evaluation of potential effects of Plastin 3 overexpression and low-dose SMN-antisense oligonucleotides on putative biomarkers in spinal muscular atrophy mice

Eike A. Strathmann, Miriam Peters, Seyyedmohsen Hosseinibarkooie, Frank W. Rigo, C. Frank Bennett, Phillip G. Zaworski, Karen S. Chen, Michael Nothnagel, Brunhilde Wirth

PLoS One. 2018; 13(9): e0203398. Published online 2018 Sep 6. doi: 10.1371/journal.pone.0203398

PMCID:: PMC6126849

Abstract Article PDF–3.1M

Select item 598676915.

COMP-prohibitin 2 interaction maintains mitochondrial homeostasis and controls smooth muscle cell identity

Yiting Jia, Meili Wang, Chenfeng Mao, Fang Yu, Yingbao Wang, Rui Xiao, Changtao Jiang, Lemin Zheng, Qingbo Xu, Ming Zheng, Yi Fu, Qinghua Hu, Wei Kong

Cell Death Dis. 2018 Jun; 9(6): 676. Published online 2018 Jun 4. doi: 10.1038/s41419-018-0703-x

PMCID:: PMC5986769

Abstract Article PDF–6.0M

Select item 591020516.

Mutant cartilage oligomeric matrix protein (COMP) compromises bone integrity, joint function and the balance between adipogenesis and osteogenesis

Francoise Coustry, Karen L. Posey, Tristan Maerz, Kevin Baker, Annie M. Abraham, Catherine G. Ambrose, Sabah Nobakhti, Sandra J. Shefelbine, Xiaohong Bi, Michael Newton, Karissa Gawronski, Lindsay Remer, Alka C. Veerisetty, Mohammad G. Hossain, Frankie Chiu, Jacqueline T. Hecht

Matrix Biol. Author manuscript; available in PMC 2019 Apr 1.

Published in final edited form as: Matrix Biol. 2018 Apr; 67: 75–89. Published online 2018 Jan 5. doi: 10.1016/j.matbio.2017.12.014

PMCID:: PMC5910205

Abstract Article PDF–1.0M

Select item 564066717.

Lubricin binds cartilage proteins, cartilage oligomeric matrix protein, fibronectin and collagen II at the cartilage surface

Sarah A. Flowers, Agata Zieba, Jessica Örnros, Chunsheng Jin, Ola Rolfson, Lena I. Björkman, Thomas Eisler, Sebastian Kalamajski, Masood Kamali-Moghaddam, Niclas G. Karlsson

Sci Rep. 2017; 7: 13149. Published online 2017 Oct 13. doi: 10.1038/s41598-017-13558-y

PMCID:: PMC5640667

Abstract Article PDF–3.7M

Select item 460562218.

The Angiopoietin-1 Variant COMP-Ang1 Enhances BMP2-Induced Bone Regeneration with Recruiting Pericytes in Critical Sized Calvarial Defects

Hyuck Choi, Byung-Chul Jeong, Sung-Woong Hur, Jung-Woo Kim, Keun-Bae Lee, Jeong-Tae Koh

PLoS One. 2015; 10(10): e0140502. Published online 2015 Oct 14. doi: 10.1371/journal.pone.0140502

PMCID:: PMC4605622

Abstract Article PDF–5.4M

Select item 450136119.

Intermolecular interactions of thrombospondins drive their accumulation in extracellular matrix

Dae Joong Kim, Elena D. Christofidou, Douglas R. Keene, Marwah Hassan Milde, Josephine C. Adams

Mol Biol Cell. 2015 Jul 15; 26(14): 2640–2654. doi: 10.1091/mbc.E14-05-0996

PMCID:: PMC4501361

Abstract Article PDF–6.0M

Select item 420994720.

Pseudoachondroplasia/COMP — translating from the bench to the bedside

Karen LaShea Posey, Joseph L. Alcorn, Jacqueline T. Hecht

Matrix Biol. Author manuscript; available in PMC 2014 Oct 27.

Published in final edited form as: Matrix Biol. 2014 Jul; 0: 167–173. Published online 2014 Jun 2. doi: 10.1016/j.matbio.2014.05.006

PMCID:: PMC4209947

Abstract Article PDF–642K

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